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JxX cb.bn5. rPerceivaml - win. Ee S3D:eBI3::: -- SpEooomnmee E BRT REe. mow: eau ism April 7, 1981 de 226-15F ARBORS C-8 CONCCEETNITARTXIEOINONh24p0 ORGANIC FLUORINE She ateashed sable vas prepared to answer a question by I. A. Lundgaard which was relayed by Lance Percival 4/3/81. He asked if there was a correlation between airborne C-8 and organic fluorine in blood. There is not a direct correlation as with some materials where an exposure one day may appear directly or as a metabolite in the urine the next day. C-8 accumulates in the blood and is not readily eliminated from the body. Therefore, organic fluorine in blood samples is usually the result of exposure over an extended period less She data for nononer eperators illustrates the deilfifmeirneantcieosn wihnicbhodymaychveamirsytrbye.tween individuals depending -on persistence of C-8. Seven long-servic monomer operators who mfalyuohraivnee bleeevnelexofpos0e.d35 tpopmairibnortnheeirC-8blohoadd wanhicahverisagetohregsaanmiecas the background level for organic fluorine given in the answer to question 17 (". . . organic fluoride blood levels ranged up to 0.4 ppm."). We do not know if this was naturally occurring o2rgyaenaircs mfolnuoomreinre soerrvCi-c8e. preThcreedeedmboynom1e5r yoepaerrsatfoirnse. wphoowdehradasebrovuitce had an average This must be a coragrarnyiocverfluforroimneexploesveulreofin 5.t9hepirpmfiinnetphoeiwrderblood. assignments. The level is similar to current fine powder operators w0h.2o htaod2o1.r7ganpipmc. fluorine in their blood : samples ranging from BE ones Z PT/nsw g 3 > EID080710 000048 ! TEFLON DIVISIONS . - AIRBORNE C-8 CONCENTRATION AND ORGANIC FLUORINE IN BLOOD SAMPLES AREA MONOMER SAa MPLEy S AVERAGE C8 mb `ORGANIC FLUORINE IN BLOOD smpre(s2) . . AVERAGE : MMER YEARS | RANGE AVERAGE SAMPLED IN TEFLON Pm _pm 99 0.4 @) ( 3 2% 01-05 0.35 17 5.3-6.7 5.9 FINE ROVER Polymerization 0.7 18 10 0.2 -21.7 7.0 Finishing 1.4 14 7 0.5 - 5.0 2.4 FE Polymerization 0.7 13 2 0.9-50 2.8 (1) Taken between October, 1979 and March, 1980. @) TakeninAugust, 1979. (3) ong service monomer operators. (4). 1S5ho-r1t 6syeervaircseimnonfoimneerpoopwedreartaorrsea(.1 - 2 years); previously worked (5) Mote - thesearetotalyearsinTeflon. Many peo hap dselvereal assigments with different C-8 exposure potential. . o> . . 4/7/81 = 1000049 EID080711