Document k6mkOOwV3Q6vnNwoKod8YymYn
fit 0001660
J u ly 17, 19U*
Dr* H. B. Haag,
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Departm ent of Physiology and Pharmacology,
M edical C ollege of V irg in ia ,
Richmond, Va#
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Dear Dr* Haag:
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I th in k you q u ite ju s tif ie d in your doubt as to the ex is
tence o f any danger asso cia ted w ith the using of in tra
venous m edication co n tain in g le a d to th e e x te n t o f one
p a rt in a m illion# I t should be p o ssib le, of course, to
elim in ate the g re a t r p o rtio n of th is lead from prepara
t i o n s u s e d in tra v e n o u s ly * On th e o th e r h an d , t h i s i s
sometimes a v ery se rio u s te c h n ic a l d if f i tu lt y , and under
c e rta in circum stances, I th in k such q u a n titie s could be
p e rm itte d to be p re s e n t. O bviously, where i t can be p re
vented e a s ily , i t should be done*
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O b v io u sly , some c o n s id e r a tio n m ust be g iv en to th e quan
t i t y o f m a te ria l a c tu a lly I n je c te d / The q u a n titie s o f
le a d p re s e n t from t h i s so u rce in sm all ampule would be
w h o lly i n s i g n i f i c a n t * a 10 ml* ampule would c o n ta in o n ly
10 m icrogram s, w hich, o f co u rse, on any b a s is , is u tte r l y
u n im p o rta n t. M oreover, a t th is con cen tratio n of le ad in
s o lu tio n , no d i r e c t a c tio n ' on th e b lood o f ah^ k in d i s to
be expected* - ' ' . ' ' ,v
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In c id e n ta lly , I should be su rp rised i f m edications fo r in
tra v e n o u s use? c o u ld be found c o n ta in in g c o n s id e r a b ly la r g e r c o n c e n tra tio n of ; le ad than you have mentioned* C onsidering the dosage used by . lair B ell a i^ h is a sso c ia te s, and by
a number of w orkers in th is country in th e treatm en t o f can cer w ithout untoward e f f e c ts , I th in k no one should be un d u ly w o rrie d a b o u t th e s e m inute q u a n t itie s * .. ..................................
I am c e r t a i n l y v e r y 'g l a d to h av e h e a rd from you a g a in , and
I t r u s t th a t mtfcers w ill a r is e to n e c e s s ita te our c o rre s ponden ce. I am n o to r io u s ly b ad a b o u t m a in ta in in g my c o r r e s
pondence, u n le ss th e re is som ething which has to be attended* I am a l i t t l e ashamed o f t h i s , b u t I n ev e r seem to be a b le to do an y th in g about l t * ; However, I do answer l e t t e r s th a t a r e w r i t t e n to me*
P le a s e a c c e p t my k in d e s t r e g a r d s f o r y o u r s e lf and D r. Main*
C ordially yours,
liE t