Document k6KG1LXEGX0ev9EDKjwD8NngV

Shanghai Health Study December 2006 - Proposal for Path Forward I. Study Objectives o Shell: Partial funding with clear recognition of expectations. o Shell: Reputation, not financial o Shell: Not to be put in this position again in 3 years CC study stops at x cases or by YE07. DP will be a regret ME should focus on lymphocytic effects Data published. A. Where are we today? Activity STUDY Lab Pros Diagnostic services to Shanghai hospitals Tissue bank Database Cons Fudan does not want to sustain lab Staff retention AMLsINHLs Subtypes identified 18t use of WHO classifications Small % BZ exposures Question regarding ability to reach 500 cases Exposure Assessment Disease Progression Sector analysis only NHL Consent forms and exposure assessments missing Will there be a dose response curve or threshold? Molecular Epi Hard to get into factories; not many volunteers Publications BUDGET 7 - mostly methods and literature reVIew New data: BIMDS, nutritional anemIas 1 SH ELL-MCCLU RG-0682S4 B. Where do we want to be? II. What is realistic to fund? (Barriers and obstacles) Activity Fund Lab transition Case Control Disease Progression Molecular Epi Exposure Assessment Irons T&E Analysis and Publication Symposium Closing Ceremony SRP ERP Legal Communications API Funding Level Justification 2 SH ELL-MCCLU RG-068255 III. Controls to support objective A. Prioritize work B. Robust QAlQC process C. Metrics to measure progress reports monthly, bi-monthly, quarterly D. Project management E. Final budget with an end date IV. Path to closure A. Budget B. Time Line 3 SH ELL-MCCLU RG-0682S6 Shanghai Health Study December 2006 - Proposal for Path Forward I. Study Objectives A. Where are we today? B. Where do we want to be? II. What is realistic to fund? (Barriers and obstacles) III. Controls to support objective IV. Path to closure SH ELL-MCCLU RG-0682S7 November.200SConsensus Timeline.for.Shanghai.....eal1:h SludY (J) I m r r sI : () () r C ;a G) oI (J) ex> I'V c..n ex> Timeline for Shanghai Health Study I 20074 I I 200R I Nov 2005 Annual Meeting 2H05 Progress Report I lH06 Progress Report Timeline Considerations 2006 Annual Meeting Benzene Symposium Data collection complete Data analysis complete Final Results - Publications Lab Transfer 2H06 Progress Report I lH07 Progress Report 2H07 Progress Report I SH ELL-MCCLU RG-0682S9