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71 f Industrial Hygiene Digest INDUSTRIAL HEALTH NEWS LITERATURE ABSTRACTS MEDICAL ENGINEERING CHEMICAL TOXICOLOGICAL INDUSTRIAL HYGIENE FOUNDATION MELLON INSTITUTE 4400 FIFTH AVENUE -i- PITTSBURGH 13, PA. SC-ALL-06830 SCF-ALLF-01760 ,,*.*. f*;.h ' VvV:> V-the'hand!tag ot thefe'fbr^niLUtto&^r^i -> 1W - bu'sU were conducted tp Orde.|;pjoy|jC " of the eye bUtrdl^httnil(Ui)C tlkodi____ _ _ . -- ...., Voll.'AA second purpose^wia to^ter^ne the natur And eitchtof comeat" 1 prodiiced'by lastillaUdq.of .the detergont^ddlttris into the eye. - ] : The DSP white -pll Ofa* u*ed alone *5 % control and e-5 percentaouB flake'* wu Included for comparison;^ The'detergent additive^apparently-dldnoVi action of the USP white oil 4* iodic*ted by the fact'that the degree of iespopspi the teat substance* compared favorably with thereapooae produced byjthjT^iid^-^, The loatillatioa of the soap 'solution caused ao * than that produced by'the other test materials, recovery.wag completeivhen dosing was ` produced experimental procedure, by accidental <v- hantrtol Hygiene P<gct September, 1956 " *1188 A Study ol Respiration In Pulmonary Asbestosls. H. Bastenier, H. Denolln, A. deCoster, and M. Engleat. Arch, maladies profess. It, 546-553 (1955). French. la order to test the respiratory value of longs affected with asbestosls nine cases were closely studied. The sevea men and two women had been exposed to asbestos dust, 1,000 to 2, 000 particles per cu. m. . for 18 to 30 years. The patients displayed definite symptoms of asbestosls with troublesome cough and dyspnea, and all showed x-ray shadows like ground glass extending peer both lungs. No tubercle bacilli were found in any case. A definite reduction was found in vital capacity, but the maximum expiratory volume was satis factory. Breathing, however, was accelerated by hyperventilatioa. At rest breathing was sufficient and satisfactory, bat on exertion dyspnea appeared, varying considerably accord ing to the pathological lesions in the longs. These functional changes were In no way differ- . eat from those seen in other cases of pneumoconiosis. .Varying emphysema was found, but no special strain was thrown upon the heart. -- Coud. from Boll. Hyg. 1189 Asbestosisr Report of a Case. E. R. Wiese and W. E. B. Ball. Diseases of Chest 30, 229, 230 (Ang. 1956). r The history and autopsy findings in a fatal cose of asbestosls are reported. Conditions described include: absence of the middle lobe of the right lung; greatly, en larged heart; wide spread, sharply demarcated development of fibrosis; and degenera tion of collagen tn^extenslve irregular fields. These and other conditions are described folly. Fine needles representing the original asbestos fibers were seen. Small asbestos bodies were seen tn a few areas of focal fibresId, although they had not appeared in the sputum. 119.0 New Viewpoints on Pulmonary Cancer in Asbestos Workers. H. BohligandG. Jacob. Deal med. Wocfaschr. 81, 231-Z33 (Feb. 17, 1956). German. The following distinguishing features have been attributed to the lung cancer that has been recognised as an occupational disease of asbestos workers: (1) increased inci dence; (2) development at an early age; (3) dependence on duration of exposure to asbestos dost; (4) a latent period between onset of exposure and the appearance of the cancer; (5) the localisation; (6).the histological structure; and,(7) the multicentral origin. The authors discuss each of these points, and show that there Is little dear evidence to support any of these assumptions, with exceptions noted. Women workers in the asbestos industry have lung cancer more often, and at an earlier age than do other women, but Ihe same is.not true of men. Malignant growths of the pleura seem to occur more often in asbestos workers than, in other persons. The multlceutxal development is observed also iu workers exposed to cobalt Sind to chromates. The study of the pathogenesis is still in the state of hypotheses, and the theory of mechanical pathogenesis is given most consideration. Microtraumas and asbestos bodies Me always found la the pulmonary cancers of asbestos workers, hut the authors Ieel ThatThis 'does not necessaray*piwveiate`imgclnheajl-4hecrry> - 3-boy-cite-eowand factors that speak against a purely mechanical pathogenesis of asbestos cancer, but they concede that the development of so-called asbestos warts proves the Irritating effect of asbestos-on human tissues. ' -- Coud. from J. Am. Med. Asset. 1191 Nasal Penetration ot Particles oi Small Inertia in Experimental Animals. Gabrielle Asset, L. E(. Gongwer, and Stella Ryan. Arch. Ind. Health lit, 597-601 (June 1956). Experiments were carried out to determine the nasal penetration of particles of small inertia in dead rabbits, dogs, and guinea pigs. The heads ot the animals, or the entire bodies, were exposed in a wind tunnel to an aerosol consisting of particles of 1.3 . microns with density o( 1.2 g. per cc. and moving at a rate of 2.5 mph. The concentra tions of the aerosol entering the nasal passages and of that leaving the nasal passages were determined. It was found that there was a significant difference in nasal penetration be tween the guinea pigs, on the one band, and the rabbits and the dogs, on the other hand. Wind direction had no influence on the nasal penetration ot droplets oi low inertia. ' -- Authors' summary AFFIDAVIT OF DAVID S. EGILMAN STATE OF MASSACHUSETTS ) ) COUNTY OF NORFOLK ) ss. Before me, the undersigned authority, personally appeared Dr. David Egilman and swore as follows: 1. My name is Dr. David Egilman. I am over the age of twenty-one years old and am otherwise competent to make this affidavit. All of the statements contained in this affidavit are based upon my personal knowledge and are true and correct. 2. I am the custodian of records of the Industrial Hygiene Foundation. 3. I have personally reviewed the documents listed below, copies of which are attached to this affidavit, and can attest that the attached copies are true, complete and correct copies of Industrial Hygiene Foundation documents. Participants in Seventh Saranac Symposium with attached Affidavit dated May 21, 1991 ofMichael Rhode, employee ofthe Armed Forces Institute ofPathology, custodian of original archives ofDr. Arthur J. Vorwald, authenticating the listing. (SCF-ALLF-01290) Industrial Hygiene Digest, Industrial Health News, Literature Abstracts, Medical, Engineering, Chemical, Toxicological, Legal. . January, 1950 (Vol. 14, No. 1) (SCF-ALLF-01180) Industrial Hygiene Foundation, Industrial Hygiene Digest, Industrial Health News, Literature Abstracts, Medical, Engineering, Chemical, Toxicological, Legal. . September, 1952 (Vol. 16, No. 9) (SCF-ALLF-01370) . Industrial Hygiene Digest, Industrial Health News, Literature Abstracts, Medical, Engineering, Chemical, Toxicological, Legal. September, 1956 (Vol. 20, No. 9) (SCF-ALLF-01760) Industrial Hygiene Foundation, Industrial Hygiene Digest. April, 1957 (Vol. 21, No. 4) (SCF-ALLF-01830) Industrial Hygiene Digest, Industrial Health News, Literature Abstracts, Medical, Engineering, Chemical, Toxicological, Legal. August, 1960 (Vol. 24, No. 8) (SCF-ALLF-02040) Page 1 of3 Industrial Hygiene Digest, Industrial Health News, Literature Abstracts, Medical, Engineering, Chemical, Toxicological, Legal. March, 1961 (Vol. 25, No. 3) (SCF-ALLF-02140) Industrial Hygiene Digest, Industrial Health News, Literature Abstracts, Medical, Engineering, Chemical, Toxicological, Legal. (SCF-ALLF-02310) Industrial Hygiene Foundation, 1967 Annual Report. (SCF-ALLF-02836) Industrial Hygiene Foundation, 1969 Annual Report. (SCF-ALLF-03082) Industrial Hygiene Foundation ofAmerica, Inc., Report ofPreliminary Dust Investigationfor Asbestos Textile Institute with attached Memorandums on Plant of (various companies) Supplementing the General Report "Preliminary Dust Investigation for Asbestos Textile Institute" ofJune, 1947. (SCF-ALLF-01000) Members ofAir Hygiene Foundation / Industrial Hygiene Foundation as ofNovember 30, 1937 through 1983. (SCF-ALLF-00470) Air Hygiene Foundation ofAmerica, Inc., References to Recent Literature ofIndustrial Diseases, January 24, 1939. (SCF-ALLF-00565) Foundation Facts, Vol. 3, No. 6 with attached Digest ofIndustrial Hygiene, Literature News - Developments, datedJune, 1941. (SCF-ALLF-00685) Industrial Hygiene Digest, Industrial Health News, Literature Abstracts, Medical, Engineering, Chemical, Toxicological, Legal, Foundation Facts, August, 1957. (SCF-ALLF-01875) An Epidemiological Study ofLung Cancer in Asbestos Miners, Industrial Hygiene Foundation Report by Bruan & Truan; study made possible through a grantfrom the Quebec Asbestos Mining Association (Note: date takenfrom published article), June, 1958. (SCF-ALLF-01939) Industrial Hygiene Digest, Industrial Health News, Literature Abstracts, Medical, Engineering, Chemical, Toxicological, Legal, May, 1963, Vol. 27, No. 5. ( SCF-ALLF-02375) Preliminary Program, 28th Annual Meeting, Industrial Hygiene Foundation, October 23-24, 1963, to Mr. Wagner. (SCF-ALLF-02441) Industrial Hygiene Foundation, 1964 Annual Report with attached membership list. (SCF-ALLF-02468) Industrial Hygiene Foundation ofAmerica, Inc., Asbestos Bioeffects Researchfor Industry, Medical Series, Bulletin No. 11, 1966. (SCF-ALLF-02683) Page 2 of 3  -V Further, affiant sayeth not. David S. Egilman, MD, MPH Commonwealth of Massachusetts Norfolk, ss ^SUBSCRIBED AND SWORN TO ME, on this day of May, 2006, to certify which witness my hand and official seal of office. NOTARY PUBLIC IN AND FOR THE STATE OF MASSACHUSSETTS My Commission Expires Vn\<