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ARARG -- 1452 L Lo ean J.C, LEITINGER - WW * E. 1. bu Pont oe Nemours & CompaNY WILMINGTON, DELAWARE 19898 PLASTIC PRODUCTS AND RESINS DEPARTMENT `PERSONAL&CONFIDENTIAL , August 9, 1978 - ' . W. A. BOWER - WASHINGTON WORKS . `MEDICAL SURVEILLANCE PROGRAMS Fogle The attached letter response of August 3 from Dr. Karrh s3utmWmaasrihziensgthoinsWorrekcso.mmenCdopaiteisonsofaptpheliJcualbyle2t4oa`nbdotJhunCe-8 16andleTtetelrosm,er-A ptloawnhtipchhyshiecireafnesrsw,illareconatpapcetndeDrd. aKlsaor.rh Idtiriesctlaysswuimtehd athnayt qutehestions and in connection with medical record reviews, R. M sl HERD : ENERGY & ENVIRONMENTAL AFFAIRS MANUFACTURING DIVISION RIS: 1db ' Attachment 32 2 : EID080236 E bern Tes ron BETTER LING'. TuReUH SXEXETIY 000130 CT E. 1. bu PONT DE NEMOUR&S COMPANY. WILMINGTON, DELAWARE EMPLOYEE RELATIONS DEPARTMENT - : August 3, 1978 R. M. SHEPHERD PRSR . D-12019 . C-8MEDEIXCPAOLSURSEURV--EILWLAASNHCIENGTPORNOGWROARMKS Reference R.M.Shepherd to B.W. Karrh, July 31, 1978 Dr. FoderarIohhaaddrceocnetiavcetdeda Dcro.pyAlofvayroaudro laettWtaesrhitnogtH.onMoWnocrkusr.e, Tahned Ara+, || pSleacnondtsheyofaegmrpeledoyeteoswawshofohradDrb.eeAnlviadreandtoiftioedreavsiepwretvheiomuesdliycahlaving w#a3e4 | bfeienndinegxspostehdattocouC-l8d pcoomspsoiubnldys.be rHeelwaoteudldtobeocsceuapracthiionngalforfaactnoyrs. 4 | We have not heard from Dr. Alvarado nor have we followed up. sy} tially expTohseedMetdoicCa-l8 aDtivitshieonWasrheicnogmtmoenndsWortkhsathaevmeplotyheeessampeotmeend-ical #81 WE `| Surveillance program as was outlined in my July 24 letter to F. E. French. You will note this is our regular periodic examina- TM ttihoenCoamnpdansyh'osuldpebreiodciocnduecxtaemdinaattiotnheprsoagmreamf.requTehnecrye, arceonnsoistent with . > orfecoemxmaemnidnaattiioonnss ffoorr esmppelcioayleesteswtoirnkgingnorwitfhorC-a8n. inTchreeasoendlyfortehqeurency 77{"))| proetceonmtmieanldateixopnosuirse ftoor tthheossee ceommpploouynedess &idxentotihfaiveed tashehbalvoiondg htaedst for 77"i4 ||hfa1vveo:roechsenticaalsb. tlhHeoiwbeasvcekrhg,reotuhdnedseletveestlsofshfoluulodroncohtembiecadlosnepruensteinlt.we (#7. ) |iMnetdihcealbDliovoidsiofonnoansexspooosnedaspJerascoknsso.n LWaebowrialtlordyocatnhistakien otuhre blood FoH e | specimens. : You also inquire regarding my June 16 letter o F. E. G1 FfrorencDhu Paboonuttemtpheloyaepepsliwchaobsielitjyobsandhavsetatpuostenoftiatlheforrecoemxmpeonsduarteisontso Fluwvbodysimilar fluorochemicals. I recommend that Washington Works follow 2 melw=tyhoeuswaimlel rseveenc.aoctigonnize thaptoiAncttsioansPoouitnltin4edwiilnl_tbheatdolneettbeyr.theHMoewdeivecrayl ivision. Cust wed FTor fr Ly _ o.r commentsP.lease contact me should you have additional. questions . .BK/ag BD0ss7 pA ar 2 BRUCE W. KARRH, M.D. . THERE'S A WORLD OF THINGS5 WiEe AREane DOING SOMETHIN, G ABOUT00|0131 E. I. bu Pont 0 NEMOURS & COMPANY WILMINGTON, DELAWARE EMPLOYEE RELATIONS DEPARTMENT Bi . - k . July 24, 1978 F. E. FRENCH cose + . MEDICAL EXAMINATIONS FOR FLUOROCHEMICAL WORKERS exposed to3uf'lsuorpohcyhseimciaclalesxawmaisnatsioomnewphratogrlaemssfeoxrtweonrskievrestphoantenotuirally remopultoiyneeesp,erisoedlieccteedxabmeicnaatuisoentwhietihr ojnoebsexhcaedpttihoen.greAatefsetw 3pMotential ' tfoordeftleuromrioncehemiifcatlhereexpowsausret,hircekceeniivnegdofspetcheialboxn-ersayCsonosfisttheentpweilvtihs fluorosis. Incidentally, these x-rays were negative. workers shOouurldmebdeictahle rseugruvleairllaDuncPeonetxampienraiotdiiocnsphfoyrsicfalluorexoacmhienmaitciaol: consisting of . . aanheeaxlatmhinahtiisotnorbyyqourestuinodnenraitrhee, supervision of urinaalpyhsyissician, - 12 ballokoadlicnehemphiosstprhyattaesset,s b(iglliurcuobsie,n, BUtNo,talSGOpTr,oteLDiHn, wi aclrbeautmiinninaen,d gurliocbulaicni,d,caclhcoiluems,terpohlo)sphorus, 7 hehmemaotgolloobgiyn,tesHtesmat(ovchriitte, anadndrrededblboloooddceclelllcounts, . indicies, . vauidsiioognratme,st, 14 x 17 Height, wpeoisgthetr,iob-laonotderiporresscuhrees,t xa-nrdayp:ulse, . SEclreecetnrioncgarpduilogmroanmasryatfutnhcetiornouttiensetsin(tFeErVv1alasn.d FVC) I recommend we not include special x-ray examinations. BUK/2g Ls, karrh, #.D. - EID080238 : THERE'S A WORLD OF THINGS: WE ARE'DOING SOMETHI"NG ABOUT 000132 o fa m apn . pr E. 1.g'ou Pour ozNewouns & Company . WILMINGTON, DELAWARE EMPLOYEE RELATIONS DEPARTMENT HT. MWo.ncHuarnea,vanP,rihLegal SJI. PFeoldle,raErRoD,.D. B. C. McKusick, CR&D . June 16, 1978 Fc.osEe. FRENCH . B 17264 FLUOROCHEMICALS IN BLOOD : fluorochem3i4calhsasinreptohretebdloofdinodfingpoFtCe1n4t3i,allpylusexoptohseerd wuonrikdeernst.ifieAsd . 2ynedt', thneo sadivgenrisfeicahnecaelthofetfhfeescet hfaisndbiengesn diesteucntkneodwni.n tThheseesewocrhkeemriscals choarvreelaaltsioonbeweinthdettehcetebdloobdy tteessttsreonsultthse wbourtkeirns'veruryinsem,allwitqhuagnotoitdies Saimfielwartesttesstshavheavebeenontdobneeenondonpelanotn othfeficgeenweorraklerpso.pulation, although action forThDeu MPeodnitcaelmplDoiyveiessionwhorseecomjmoebnsdshavtehepoftoelnltoiwailngfocrouresxeposofure to Telomer A and its non-polymeric derivatives. : 1. poet 2+. Qi(3. aE . br 4. 41.%..7) ,8* hx #740%As 5. 4 y+ 4 1 cRoenvtireowl-salltocuirnsruernet tohpaetrattihoenspotanedntiianldsustfroiralexphoysguireense are properly controlled. wIodreknetdifyjobasllienmwphlioycehesthwehroe cisurrorentwalsy wpoortkentoiralhavfeor exposure to fluorochemicals. eRmepvlioeywedthebymeDduicPaolnt,recloorodksingoffaolrlcosnuscihstpeenrstonosr usntuislulal health occurrences or trends. Onbetvaeirnhabdloopdotefnltuioarlochfeomricoaclcuplaetveilosnalonepxeprossounrse wthoo have aElbuaosreolcihneem.icalTshesteo teessttasblicsahn bbeackogbrtoauinndedloenvelWsilmfiorngton eofxfaimcienateimoplnlosoyy:egeisvenasian ptahretNeofmoutrhse Mpeedriicoadlicfpahciylsiitcya.l eObmtpalionyeebsloowdithflvuaorrioocuhsempicoatlenlteivaellss ofnorreepxrpeossuernetsatitvoe various fluorochemicals. If this is done at the same EID080239 - = THERE'S A WORLD OF THING"S WE ARE DOING SOMETHING ABOUT 000133 pal --2- time as the employee's periodic physical examination, a "comdporcuemheenntastiivoen eofxamthienatriesounltssh.ouAldubreindoensepewciitmhencasrheofuulld "ibne_-tohbeetavineedntfo--rtlhateer-abplaioyoaiids--folmraerFkvieuedfllryocehleenviaeteld]:TToevveel - : 6. Rfeorviecwonsthiestepnhtysiocralunufsiunadlinghseaolfththoeccwuorrrkenecresseoxramitnreendds. "1 -l When such occurrences or trends are found and appear p4o57nd ctoondbuectsiinggnifsiicmainlta,r cphoynssiicdaelratainodnblsohooduldexbaemingaitvieonnstoon non-exposed controls for comparison. 7. sIfuffthiecipeenrtiodduraoftiopnoteanndtiatlhereexpoissuraeshuafsficbieeenntofnumber of be employees, an epidemiologic study of the mortality of qu 4 the cohort identified may be considered. A determina-. 1.hn" shut, EtnigoFnulcanstbuedymaadfeterof thtehenulmibkeerlihofoodpreofviohuasvliyngeaxpmoesaend- . wowntyl`be,nt employees is determined. : thoivsPusttsudSy48in MoerddiecralasDipvreisseinotnedr.ecomHmoweenvdesr,prwoeceweidlilngnweeidthat least ttuhoe dsatyusdytoandobthaoiwntporodpiesrcusssuppthleiesstuadnyd wiintfhormtheouremptleocyheneisc.ians of BWK/ag . pn oLL MREUDCIECWA.L DKAIRRREHC,TOMR.D. i . EID080240 LE . 000134