Document jyBJrrwzZ3g59JEZ2zpX4VkwR

ETHYL CORPORATION IXTER-OFFICE fORRESTOXnEXCE xo Dp . R. A. J[isk>e a d d r e s s Cincinnati f r om J. S. Boudreau a d d r e s s New York SUBJECT dat e April 18, 1966 Dear Bob: I have your letter regarding the White Horses. Please have no fear that you are in any way being a nuisance to me. In view of the fact that my contacts are in Washington and your date isn't until September., I am going to see my friends there when I am down for the lead investigation in May. This will still give ample time. If that falls through, I now have another lead. On Saturday we in vited some new neighbors to the house for a drink. Both the man and his wife are Swiss and he is a doctor with the Rockefeller Foundation. He is quite an avid horseman, and both he and his wife keep horses at the Hunt Club in Darien. In the course of the conversation he mentioned that they were going to Vienna next month and were particularly interested in the White Horses. I remarked that this was rather a tight proposition with all the tourists today. He said that he had no problem because the head of the Spanish Riding School was a very close friend of his and he has visited them a number of.times. So I am sure that one way or the other, I can^get you, your wife and Kathleen in. I talked with Dick Scales this morning and he said he had outlined to you the nature of our appearance on the 26th. In view of the fact that on that same day they are throwing in sulfur, boron and a number of other things, I am very hopeful that we will be lost in the shuffle. One of the remarks dropped was that all presentations should not be longer than 10 minutes. I don't think that should cause you too much concern for I am sure that George Kirby will be glad to relinquish part of his time if it is necessary. C\, ^ I am attaching a copy of the boiled down version of your original V'i/ ^ paper. Although I understand you are working on a new version, I think that ^ the attached version, which can-in turn be greatly reduced, might give a very good overall background of the situation At any rate, I would be most happy -J to work with you as soon as you let me know. jT : yc C-*- With the kindest regards, perely.  * s\ ; * -u- l'K*'X S: %=`a_s'- .> ,r-- aiS'-r. .-*- -w-.vi " ; /J ;*s ~v\, y* ;-x> - X, VSbi '* .W `VtL nTOififlscif xaciixus or vcci^wtifiHiii maicmii jsepcrtOBSt or isriviyosBffissr&cy, . Health, C&3J& of itodicim, University r Cincinnati, etoeisaotlt^po^:' - - . -::f'' -': ' .". v :' ; ;' ' 1% is the 9(8*9060 ocr thin stoteawt to present ilk brief fft *;. !*$*, -- 1 ** -v- 7-s^^yv^^ ->v>r-_ salient facts concerning the hygienic aspect* of the occurrence and 4i*tri *'' ,V butloa of lead la the tsavlrosasaeafc with particular reference to the contribution . .. _ Jy thS~ SSS Of gaywHtM, ow^-ftlrttng 1A -~ *- , y-*ir> "''Vi A^. -, V 8(6 er^tefl fa ^jtrt&l& clfcX(6 ^g| little lajonKtlot 1 avttllafeJLe a *iihi***it^ ji>m<4*iw Ia to tattoo mlfttit la Wn ^v. safety of thejobhie* ' ,* t * ,* t.'i \ * V The fact ltfj hovevar, that no other hygienic profedUai la the floid of air pollatioa hs hesa ixtyesti^sotsa o ovor ftocfe * period of ttee# aad vlth saeb defiaitiw rasalte. This Is not to there urn m siaifieaat voids la the amllahle laforastloa^ aor t that a_ >ll of the ultlaat aarvexs ers t hand* l^tvorthftlcss, it is elewr that tl k opoclf1c set of prohlsss has hsea hroa^t to sueh ft poiat of unAsrsttwllftg^ ia roUtloo ^ ?'*`T to the pta^Lie health, ft* to rcsoaa it n the rsfths of 'ia&emy: aaki to^mtieft1', >4 ^t5 .* ^ it Into that group'of % 0*, < prohleew sfcteh so *ffSetiv <wrvsilUtnc'-': ' L; **( * r- shonhi W hspt* A otmaidsrftbi* taeesnrs of sssuraiies for tho fetura my slso ^:; be derived froa the fast that mthofis of surveillance have developed, over hj\ the years, vMeh era ehfirfeeterisei by a Mgh a$r of tachnical predslott and 3 , physiological ralsvaaes* /**i J 1V v ' ;f ' <i--i 5< * " ** ?'. ., - .; J-tr Tho results of all those investl@atioos to date, shioh srtesd bach . . ' f over the past forty years, have consistently dcoonstrated ttets Cy*. .'..* ;. K 0018247 A.^'W V ' t 42 N22261.01 rested tests* t tte health Of t >, > '~- ` *,-\, f* *te cenowsfcwfclste of teed froa tH ^*^**"- ' of teerieen cities m te* ,. 3* tte waoiusta of teed to vhieh tte eeaerel population sre exposed f .tep - ; t ,v A U courses, iaeladii^ foods sad teveregee'<* sre tehee tested** Unit*. *u poring the past tsosty-odd yesra* there' teg teen little # Ofttl* x-v'' oftst of the ^Vineries,* s^tnit Anerleast, ^'tr^yy V-/- ' 4 >* fstebis oc* v, -- . of lead, or la the amounts of lead retained la his body* Sate slight * 4`i.* V/.-JJi> s`r?>j< ' V* *i* V/f '^'4Vs3 " eteng*r m tee been observed tes news* la the direction cf decrease is. both intake sod output, test It is not certain ttet this apparent tread . ',' f.'./V;. fS* >*' V v wW* i- * v3 i . .-v-V : is reel in tte sense of being s re^ssotettfoa of getters! sltMiite* ':; .v } . * 'iP-r fte bulk of the iaveetlg&tive work vbtch bears on teed in tte eaviroeaeat of sen te* been carried oat in the Kettering tehars^ College of of tbs University of Cincinnati, usds? the flttuolil ' of tbs ettmafsottsper of 7 Tv***ff aatlteo^c .eoispoends* Btea this cork first began in tte ittaen*hndr^ there f -:< nee- on appalling inch of fkcllltiei for yeecsreJs in these Jfieldaj in KilvenitiM^ la pn^rxsninX eirelee, end in iafiustry* . ->U ' - `I', V V`-' .V. ; ~'U: - .V j! -.'.V; '-- . - '^.th Tn Sh4: grtWttltYi iadnSteiOS* <M>twS4M> tte .fcthMiSle ladSlltrT* " ' 'pPP-; V V'-::r ;: ; 'V twwwd to the tMvfFSity of Cjsef'Wifttt fw ''' ;; ' \f' '.-r taSirriMitiflii sisl '.'^^ ^V/V^Pv--'- ;. '- ' ; ' :'. ' ' i'"-';;V--.yVrV> ; ,,;. sdedLee on *ees*> to **<* hs%.lealc mMumytm in their w*Q* ip i meldlr p*^ >. ^v>' -v/V -- > ` * '^f psadis^ tecteoXopr* fteef tte eatiteecfc ia&smtst provided tte fisenciSl eappert f that ted to tte ee^teilUUtteent tte ghtterl&s tehorstorjr, tte# *xM:v+ * vith tte Board of blrectora of the tfaiversitf sad oith prteery reapeet to tte - .. ' v-0-V,,'U:;,-', ,. ',...: .: ^/r -- -. - , , .. ;/' poUclea of tte Caivcreity. ,v: '*V,' ,;*>.. * 'Os^Sv 0019248 * % >- rJH*;:-I -V. v. The Kettering tobaeotary ha* otoce^'g^bs^to nstorltor toy*tosliar . pm * , * ` , ' AiLUiJ4>^ pd&djU-tS *yf0*'*1 and EfesciesHslly, a& ewer the year* hasgaltod bq toon 100 indueivlfel-- 4||fl **&*' > .........--- ....; ? ~~r in natter* rOusCed to ^ heaXtii **& *# enffidLoffiSttii* ctsrfeottera* * v--. - / f- - >-/x;:'. -.. - * v ''! toe ge^eraXijf# : Wto& toe earliest use of tetraethyllead mi mi eatifextoto vss ifseogalzisS O**^ thi <t<*>>Hni^ q j 'jftftwi ^bt fyf * yips* of it * *> '0X ^ <* vehicles ^ywf4y^- * Mrious |wy.i.o,..f.|...q.....'.y......p......^.....i..^. y . gg this *m,^;f:$m >: : (-./' . ; -" 'V,: - ; -. -v > li^Y"',\i^ Investigation ef the h&sard of ilrksnw ^^ps ron to*# f^^arwi was iiiiitttft to 193# to toe Sam of litoes l&pertoeaiaX stetloa. Aboat two years : - , later, to* first of a series of field investigation# of `too caviromwirtai. 7 , f;-`''^f:; conditions and the imosol involved was designed and carried oat tar <'u'-U:.r-~ ; -^r investigator* in the Oaiversity of Cincinnati* hater to X925, ft 1* elaborate tovsatigatioa vss asde tgr ft group to the United Statems MUr^ : ^-.: Health Service. Others foXKwed in 192T, *9^# X932# X95S sod 18^M$*^*5 throogh the effort* of the gm to the ^aiwmity of Ctootooati* ~T7 =.*.' ..',& i. these fwyyafe^g^t^Aa^j. o^f^*^***^ ooro eyM?*4fd to i. : YUU.g^id ^ . \ . * * t ,,fy-*rK, ; '!. "*'. to the repair aod ^yi of sotor vehidee la the sheeps g^1^, ef-j o`'-*-e' V- "!o` f<J'y-'V aotox fleets sad todiwidoally oesed aster care, as vaXX ns the viK.'*'- car j^rks m& yarhtof garagoa, traffie offiawh, sad taxicab oi deXireri';.. V<* t4^ twdrivers, oho are Mlieved to hare heaa subjected to awrtowt -eagbiagdf^i to the eahausted efflwests of actor wMetoft* >-! ': , ' ,-. -' i;K '''`^vvV'.V'ii' j *. , . r&$*&&:>:- Various marveys eoaeeraod only alto too co&eeatrcttoa of Xe*d"to ;- ' ; -. >- the ataoBChere of iHtiftiwati. Lesi Aaaelea aad fasadmka sera cervtod oot to 1950, 1952, 3^55* aai XS^l, by technical Setterins tohoratory* of toe staff of toft . W fj->/V"- s ;k V'- ::u;j Ooteldo Hm Halted States, farther tovestSg&ttoti* test tseeft ftsSe^ |C5 : v-^' ' -VsV. i `*, .* V, to Great Sritato and toitserlani, ^hieh eoafim toe ftofilsge of toe fiettertof /. tobcaratOKfB 0019249 '- v* ., ' ' . - -j` >;-"u 5 v ,:, ^*v# ; ', ` ' ' '-) ,o j-, .. .z...K`-'~-$ f)$&J'* tJW, %-\v^'.. * , 1 vf Al*" >" m% m *r ,` * - tp i, ' * . ". t; -> if4..**^ ^i .! c ,r V jt - ..iW ** SSuy latrSMfti ftetft. syitB IfailftfQfa*d- ~ta l<^t t IphtlrtflftlTifotftg . *\ ** ItaiUh .p - ^ TSt*afaiaaafe. rtf 3' y,<>$ Jgr & /V ,<'.- ^-.j m*'' <*' *.--, .**=* P<V3r-J >*f the gfrHsdgIpkl& Sealth SiSdrtaeafc# the California ftete -- *0,f- a -feK* gottjiflria* tjAftWltftpy. f r-' .'k* aMMWa) " - ., .. gw^a*MNfc <jf si ^OJrJtiOS fiyCRIJJ trp iyf " <-** Of ib8 A&erldSk f: 0*0 &** . 'l-'''-`. -:' - -:*:/'. v. ;;V-w..' ',. . . - , , , >. .'- "V-*7"^''' >- - ^'.' ''t ' ^ .. ' v ;' .- . ' '1; .44^`'v'/>77'^\' 7' '''.^.*: & -* > tWH&rtaffi&t of Saaltfe. tii* th* Poa!L cScxminr* fitfeyi y.>?*-jw4< - '' - ' :> ' '- : ' 'V- . ' ' - ' > <MTf*.C5 ' .......... ... A ,t ' >-'4; yt*^ t*$ th ^fbSJLc E^tjnriUs# iLs ^wEwwy sjjf f-v Mm Itm ^0 *3 thft ttiriy aiats femfir^a tMrtl# tb 9tfi 'f '.. '* ,'t ? ! - -- ?*' ^'sr- 'fe&ft Kfft-tfliyl,^ <iM*1^tl tiwi fcJwi &t)n*fc4*l hftjjaxrf* of 1m& wml^ ',.. not fe& P*^F^p ' , -. ,-j ;v^,f(i'f%l ;'i/' iv-; ay fisnniistid fe*r artnyfeHtnar afawt af wwa^haiwitii* tr.#jn*4ttfe#jM* p IPp^*p ^^ t P ^*eBW^Brei^ - vj* - - ^ / "* -C , oaoap?ttiag tfe s<mrct of lead is the gerl etsvUoaatafc, ed. the eeiMitiim ^ '- ' -f 1"-' of aaa thereto, Meojfdia^y tSwgr hegoa ft s^flee of imotigftUoMi idtiefe-^ ' . if'^'"' T ,^ir*5 -' :-"i:' ttOalmted to two eerlee of *fealai ea^dtaeftta^ of idd^. the flrt#'flU.v. : ;. ,. i^^fV " ' v X53t# i^^lved kam eafejoets to vho 1^> .fai- '-"T' / ,_____ --' i. p . * -/ v,.' . : ii. t9fd# c% Wth# la esamfailjr graded de$e^ea# aw terfod# pia^i_^m^0> ::4vC; -*>" ' " ' t - 'i' * ' ^v%' rLV k }*?* t, , 1 vW mm&LL fitmtfeo to fear years, la. *$$}, these. Iftgeotioa of lead, wo say to ofesermtloas aa to- the' hfthmiOf..ft^ divided iMgfifff eo^tMs of lead dls^^ 1% the'ftlf -* *. ' ' i* ".H, - ^ v >4 ,* sufe^eets. the. <a$*xims&9 &xsmrm$. vitathtt iahelaUm of dlila $reere^# dad are Wlag corseted to the mximm essweatratloft of re^frft&e lead sfeicfe is <Ma*^m* vitfe the'ftafletgf iffiV .W&S&mm iavastigatlosii we flisaaced, 'oata>9^| ftatfhaoeh iadastxjr .fat: Ha Whited. Bt&tes, they are. aov eostlsalad . flasaslftl s u bnost of tV^wte && otber lsdostrlel OesssdLiatieiiiit. ^E ,0019250., -'- ' \: , .., -.>;, :i.V' '. -^cC 7 >^ ^* -//w u 4 aste. ^ '--*&! -'-l ..*i*i^W5stsX5 - 5- the z&naim mi Air follaties* of tl 9* 3* 3rvi* %: ms f to* Aoag periods of tlae lxnrctibm& la individual eatperlaente, ...- -- ..;, .V.-i' ^ w* * . ;,,? /. V.-i-r.,- \ -. ..:, _, . ;--r , J ' ^ I--.-"' ' * " -". " '> ;.' ^gg. TjssisfjSjjEB&ttS Atrfafc pjjfftVljECgkffj fflf' Of . * : -.- : ; V.: . .' rfrftUltS , < .if ijgg i*im t* yaywft-pi^ -fqftl Interpreted* HT(IHllt1f| nn ahja^visto^l ?tas3s^fft^4s* u$ la iy?t $ la 12a foxs (rf* reprints of three leetareu, the tehea Lectures of tin Segal Society of JPohUc Health *a Wg&em* gives. imUeSm la 1$6&* ' ./.v;-/- :- ., :, . :................. * t - ^arfcwMyf-^ytl Wff4 ttKt '* ; '* r -V , tstrSOMtliylliaft :OHft . ? C^'*>`'<9&^*j4 OtitSXT Heyty fntO ytft# in X9^0 averego yifwyytypefoi q lead ta ^sjolia la the salted States during 1965 a* 2*1*3 grow pei `^1*48 r ; ivi,T*j*V ' <5" ' &is eooeeafcra&iaa mg 1m: &&&***& for slsgUelty es 1 fart hy valuae of . c i *' ^ S ^<a<^ jt 1|500 P*iT*tB Of ge$aXJns ,- .I#RkJk*MJk. C88wS39S nCva1T*' SXt ONJL| MSfeHTkUOk. WgMMMfMBkrtiUai MwgJXAwVl Atfctfed0fc 00019jf1l 00 IB tQO fnglflti ,' y>p4y C6ffihU^tiel 3^0^0010 OJ^BeOX* la tbs SXbSUSt gpiff SS 9LSS?gtUll0 OCMK ' posetSo of load* Galy oooaato of the f&tegi& &vsKpt the euginQ so cs to ho discbarged Soto the etxaospbere. la - v?'" Only a poritou, raaelag feat 2$ per ooat* tipnr& to 15 per coot* of >.: ' ?' ' " -- v.' '' v. - Sx*'**:' **u , tte l&ttd i^tert tit ttsdiui In tl# fiM&e is dlsthm^ fm ths tsidLdsft <'rif . of the o^caeMlo* " Of the loud which oat la the j^yton of; f* - '4;. ..V ,, / v,,-v;' the e^dLae at Zoo opoo^e of operation, nods Is <iiy^tnrgaii la iOM - ' seariod cef a^eAt^atod t5srtttioa la msd cbssdte too t** to ry--; -. \&r- ;H airhofos* 55iese say he to scout tireficatly tvwVw^ato estsat ul''Vf>- .-, ...................... '.. . rdicpered la tlbo air# % the tiros of tehiolS|> hut most of then coatima m ys&its&w too lore* for suah diepereicai. ..;/- \^%v;I '.4 : -y-:^'!-^MVBv-i:..vV .I--':' ' '&t 4i fhe cmcos^mtlcio of lead la the srtooephsre of cities imrleS frm : ' ' -^" : < Z7-:-.:*`. . - ;:; >. .. , '.,V::V ' '; , . < _ - \ \'V f^U;.'~, city to eltyf fmi one ores to soothe? is tt. city* saX trea tlos to ties dorlaa > ^<.V '' .. ? the dey, wdt, aosfth. or year. la Clnclnagti, where InfcosHrldloa has beta Oh* ft- -ij, J tslwk rre 19>i6 tlsaaeit X$S tin eoacaatnitloB tiagm troa l ntcrena ta H'e Ch S251 .' >.*V* *-:- . i36L>i- mm0<tf *to# imtemsim** m* . soaa ttWiiaal to eitatosi *m# a# totoofeeer M to&totol&l *** ' ' .'. "... -y. - . '-,1 -o ,`v-- . r,.,..., Sto total art tasr Mwatotew tot tad** M Stoat to y ' - .: ' %.. : - hr tto iMrntML msmm ee tot tor* m^aiftasfc tofitaito* ta* eta toea /tvr:- $m&& to to&eitael m&Um itos eloeg estorto* ..' - .- ...:. . ... . : : -,v V to torrdtoloa . .- .. t \ t'.r- ,H - ...... ,.w.'.. VTT vtto tto weySag torisiSy of treffto* : .'VW:-' 'V'. - !'*' :' ' > 'Y-yy';'-y:, v^;' -Vv:'y-yyy/: -y-;.yyy/' y) / .?" y-*'7^-'7> - *% -i* # n**fc* frfrwfe ttor* to* toffft ft t - &7.? totaft. to tto cN^e?toMtic to toto to tot totoegtat to Ctoetoatoi toto 4- ~ "I *****S2?-K <*T.- y- period to yeese etooe tto tofidto forties, to acsostoUtt* vito ucceifto tottoto lotto a'tottosto to tosl tosto e& to veli to etagto to' hoaetof tot irtofto j^tttoto* ' tfeto ta toe&tot ttopito It pregtotolto .to*.''- crmsQ toipitotol'totofia* j- * " *,_ -. ' / 5b!! mm: ustiKjt of o^orwtios im toto esettotot to tto n&xarn& to to. tto '^gtoa o to to partrujr, oa & ....st isroet ta% tto gensrsX s^Nwswtortotica tout to- tto toMshtn f ear eitto8*.y ^/Yy' tot to. eto^ei* toe ...... itot tototo ^ yto of remtito' toast taWtoto totetooi oier toe , yy'yyy ................. , , Y^Yi$ toferto&toa cd? toils mctm? too tosKasitovtot /'Yy ;`r.y >- ............. '*: ya ..'- ;-y , ... 'yy:^ -ttot* aidto tot tototoge totototyetito of toNt to toe etoostocre vsrtos tons1 - X*t 'ator^raas paf'a&to aetor la Cimtoasti # 2*5 si<3Wee. to toe itatoe* y ,j 2Lf-V' -.'.jffv' '-5..`.Jv.; ...;'-. rf-'V-'V-:'!" . ' ; . .:. . , r'. . -.-'. :X-. -- ..-.>. ,>..-?YTr. ... _ mSlftomce ta tan reStoetet to&&tto to2to v' ^ ' ..' .. Yt\\ `Y; ................ . , ^*-W"i; '--> -, , ;;S.;.;: eassertase of iares&tostom of toto sssttor toe tooto* ^; .^Xvi-'S &$&& ^ctoerls' ttot too eastoito of toe etoeyftore lotto r<n$e@t to iM- met to toaito#t attoto- est efetwfcttoaOJly aaier tot i#to of .. # - gOMBe ds| JlL!^v>Oa`i^' CKF Omi tiipif ifci uk t w JSvVlfii -*- *----- -- -- pitoare toto roetott to tto ^ of toto# `.jIf jSSwmMw# s&S M 'hMt Vfcif k1>' -- . - Y ^ 't- too reto eat^tireetito#'- r '* ^iV*' , ;,v i` ' ^v toair etotot tiseitobieis ere to no -. eis^si#, mu. . ,f4V.# eetoattai.^;^ mM frm e<ttet '*ai' *' tote ere 3to3Ly to to gretoiy toertoe* m..j : ; j l `r.'i * .wtM A turn starrsat mmlt& te&m tata ektaiaag ftm %im to ilae* ' '*;*' sta axsesaiTO sieoiftesae* tae Istate Mgb ' ^:f|A| .talae# Mxy ta tta *tateit el tta tatamsta* **f tastaal condition, tafe'ttajr . Vv;'-:;'| sr* sere ttfcdr to ta tta result cff agftaW'tbr^& setae fault la tta procedures ;` of seaplisg r teaO^sie* ' Of & jpfeg&ef tretk stfttiaUat&ly sal . ^^oloslcnUsv is tta fmsftiita of reo*&t of a lf n5*r of se^altade J.:.:'.' , \ . .* ` AgfaMtiiy gti of -tli ^baarvaA M<y%i rcoalta hsve tarn Iter taint tta ?&&& ttat 1* <51* tm-iU*lKpr 1*$ la any ifclvduaX SMOOt '-`-3K4 `>`-r." f- after jaany ssoatta of sspofttre* >-. a*-'. S' *.*3& It is oftaa ttat tta pat ptafsataraaee of tta lead la tat. ~2i *>;'< ataosptare* .eqpMtiiiar ttat of cities* it derived itae tta etatastioa of,-. ~,-vA|-f'-l^l-Kr " rf;; leaSs^ isaeollae. tat tta tatter la not fcHw^ eiasl* eiai aye ttat iSort f} ** - ore assy &Mttt&t fta vhicl; Iota is ^iatritatad lata tta eias^ttei'Ml^U .. V$hi)1&Z%`.'- .i'~ '.-. aost of these result ftaa tta tatititi* of ssaa taita m eotaeattata& 3tt-;' 'b^"Kl mtaa tat*r tata tat to ta foysad la nsifetiife^ ioolatta sad cpses2^ |6foi8t4 J&tatata* .tatawt .imestistaita tas fsUta to tata**sita tta' ta^slttae c*f tta- eoatritatlosio atae tgr tta na# "'If dost ftact tta earftae of tta eartb, % tta statas Sm5s of iaitatay# tad ta tta iaclaeratloa of vast* satarieie* M v4.>> ' ' '. \> A;/-;; : ;,; A ' . -. . . - ` ~'p- ' aoyice ttata to tata staistatiota ta tta tasis of tta &xm mi&m ta* mtarioXs ttat *&& to ta sotiect ta distritatim la tta tao^tae> 'vil^t., tsSdag strlet &eo>BA ^ -^s asdtl3^e tatarota* tad tta fteetors ttat 1ijftinwe ^ bygieti testa felstta to tta total coaemtartaiso ^ of load ia tta tetwa^tata frott all fioareetf la tautaUta vltb ttat ^iete is .Vs- _ - ' v7*> ' ' !& ( <. , / ^ s. * **./* * '* _- * *5*?$ VJ AU i *k4f>..,A -*&; rK `-- '-> / ' 7- "! . ..;^, ` *-- . T` 'v < .v'V-.r" : V-..'. i`~. l tbs HcmMI 4 baretfsgis eai. is say tb*p is&erial tM sjr 1## ewollowod* **,V *bie teia**. wf ssJeMsew * *&*** ywed* to tftt beetle# fplA .' *' - ... .> .. >' > : -7,'.-*. |pf%..: ' :- ` by load la tbs air tMelst they bsNsstiie#. * dejKmae&t not saSy ^oa the * i. - * &*&&* of Isaft la their astir test else t.5 tbs es&efib to; "/Vj. - VA. . .. tAldfc wh 3ss$ slss feciraac to tbs in&srsa& mS^m of tlaelr tisvse**-' It .'V. is not ay the lead thick enters the respiratory tract, tm*week at tbit la carried oat la ifc* ex&Oad air* ood It is set tbs Isaft eaters ..} Mm '- .......-. .5. ..,.,:. > 1 ', - . Aj-fc&mCy&Af* utoacysh |ftst tbat <# .... ..... - ....... _.-, f' : .. ., > . .:. ...; ISsa srars or Ifliffwlt: la Hia aaviiNixEBiKit 4sd~la frf ta^Sy la not* 3? ita^tU* a JJljg OatOCSSO to oiscSciiid# o? ftJ&S fawa is a rtliKtla# tya- .' afy^>yi<t tuya* tt#'" jgjt@ la th& <B3Et<KJfc* yi %|yf <1* rwWi<Minn9.<a aWt odP 4^tftf*Vfl*f^*1*^ *"* ' ;. .. .-. .... - i ' Si-. . istot OS' tiw *namii1 - f wwr. In :.- tiie body vlth tixaa* fteat art atltcsfi aast bs knom aad ttodontood balers oaa sgo^ca of dsagoF* . Isal la latfas^ tbo body la rirtaall)r Ixms^ea* 2ba qtiscxsittos of load ttiteea lato tbs body 'is this mams* droatly t^3 t8^3! in ith tfe<3 *><<[* la l^PISetbtB* ' - - '^ ,- i,. . ' the ttgaattUea tata is dally vitJi tbs impixiA air ars not so - k- i Ur % vail daflaad* slaoa they nost be oaealsted m tbs basis of tbe aseMse '-v - - . 1 ^^4 ; r< oGaooatratios of loed in tbs air broatbod la by tbs isdiridaal 4bal^ easb ,Vr^v 1 l " . v-r; .V'AS^I^', pieioft of 2b boom* , ; /# . -, <. ^asatitiss of lm& abuorbcd late tho body frost that tabes iato tbs adlssattayy sad. re?piyatory traots any bo detvmiaed vltb a V-A/ l\ -"s ! fs. ' ,, s^^oaabls jujc^arosy* SfersaetlssffiQtaX evldcjicys sbfiVB fiOGssMb&t f--. ''. :. .' - . A ., - ` f , .' oapw -'-'i/- -.- .i<:.:-,:^-'-"K-- *^*"` `'1. Id par oast* of that lasosted (awaUswed)* oad e*swlsat lose tbaa $0 $r aat> f7#r5 ^?-5- i'v..3r>*EVi.J T-'*-... p of tlfft iabelsd* are absorbed* 0019254 - A vi'' > ' - ***,? V t* 7- -V>.--v?; -- V-VjJ*1* --` ^*r , i*V v&vs*. - - a -"-. -.*; yw ^^aKfflfcttie# of 1***n f ffipfafa ty Mt ' : - .-;. - . " e%*dt*$nsfc -% -l~^af: 4e4*t ' ' ' " ' :. *',, :; : <- - ...'I'jf-t1' >.": : '> -r^-:.;.. - oatssst of Inal Im the t*esa a taiae, ** * |etM of atatatijr ttiwally * ' mi -nmniAn# sSi^b&y, the iaMte In ii*e ffcoi a& %#*** tMtftfgr IndlcaUBg, ".;' . / ' .. - ';v - - ; >. icfiiiSCtlSV t$S &t?ttfcQ5KlSiSSt &?&& Of /-.. .' . . , v . \ . . *i: ;.' : # fetwife '. .; - > . .vsi*.-,--... ", ..,, < / ;-- v ' rm$i?*t&c tx&st* ^ \ ,; ` r' ;*V'"Y.. " .' ... - * .; : v v ' ' . . "..jr . . - - W&sat tls& d&&itiOt& tlaat l&b & &&& isrg<tst tibs* fa* &tffiafe&fer - of lm& &bmtf3G& dollgr p ti 9jrtge Miat ot siggsgtsd -i# tskt^tal t$p6* - of lead es^a^t In M *01 ^ractlcfil Igr t&t menUotl of g ^anssii^r of b&&* msd^Mtm &tmt or <&m* rnfaztomtim, In ' osS# tisat 1^136^ I3Ues o twstwsca listaks crhi 0^9^ asy aot Imi ttg&efc* v- i' ';' -: '-i - . . *5s*ar w *t noao eUg^t, prc^&sntva *<?cssuieU4m itli tlao* ^ fms %hQmtim& -fefei mm& TJ&&1&, tmt it in tcvliMr awali In to to ^^iole^icnliy ineiijaifi^aafc* .. M to ^tenalne tfea tetnX *fcSy of iend^ ofedim- culty Xlnn la t3m fast i&sfc Xo@4 ^-gfrfcyt2m o^rfudat ottaiy ^aasattt* in # mw >. ** timt t&k .' 0|-ja<o>m^ ^ iivi^ jarfe cf tto csnssnli^f oaxidoo 00 iti BRtfilKUiS .-< X" .: -7 :'-' -' . X' '. */. . ,.X .:', . ,'- '}'" k . < .4 - <i- -' . v-t> -'V'^ anti-rttr a *2tiwly ie snto* . Scovrf the ". . mU&km to eiisar tt^na of tho oaoa t aN^ee tfa* oootost of . -X->;.^^>r:,.;---^.V ^-;V..;.^-X ..... - ...................-.-< ' .' - ' 3&sS* m&m t&Mamg GlTi^mtoxtiim to tOsast msUfi^^L* propccrtlcaa* thus ^ <*f Xoiki is the of tin * h mk . ~- <^ti -4 , r'&V1 .10/' G|>p^rs to hi. of tho ofte hoot 2 pptn 9&1* adllloa, i^l^i in aat fur -> txm the cca^eatratiani of jU&g In. ..'V' . - < *'* - ; fi ';. ' ' ;. ' tod C5?al. ms the iyEpehsXalt . ' -x;:^, X ^.:'X:' '-' -rX -- ' ' ' v\ f the Xesd in. tht ho^sr of ikm edalt' in in thet z. sort of the' hofy tiast lie M Xilseiy to he effsetei har It# a& In in lev .. otasft^Ejtpotlion is^ea theaf#* -.: . .V . y 4v . Kf 0019255 ... v' ,. >.. *'J*" ' ..: .;:.SV: ,, ^4',' *; '-*-* ^ > viSu -' - - hot it is this partial reaoval off the lead off the fco% fet <& : 'to its WtKfe8 1b vtbdtia&tii# its mamsmmtetimk&tSM. 4 <t1w soft 4Lffeg*!K* aa*# is*2y fluids* less in distcibisfeed ia the ia mmz&msm with * regcsar' . o4 S` ,i i'K .:!*,' .'c* " *. * * ; .** pabtesa ia. which ell of the tiaauest sha*o*vX& alaftfc he siopeM* therefore, ; that the eoamtretioa off loot. 1st the ceUular tJssc dctesatead ' t&roseh bloM sasSyst*, wooia M* it possible to prefect the car*Mart*ti<3a vhieh is to to ffcoadia all ether tisanes* to arrive at ths total <n*ntity la its satire body* AM so it MI| bub for tha foot tfc&t tat etsletoa, Itself* is 1y f^ thst the box'd Shafts OfthS 1*g IKMM9S <3fi gsttwdf iM<y^ it Mood autyoiy. sod la their ei&iceeftfceat s s m ' ; '; ._ '; v - -. i1, ; :.. ' ' . in tiasa in the bodily watoboitsw* This physiological iahceegeaMty pose* the ' obstacle to the dotaraiaation of the body bsrdea of load 13 the liTing . t 'V./: ;j _ _ . -; {.- * r. f v~?`.` *'*. t ,';-'l'- ;*V;* , * /. ^ ;v U r`fN"t' i'>aVl3sV*f.^- fh t yf ^*xa in the b&SOd#' 1|K WN&SS QXdlS&ry dltisns, varies to mam extent with the current arete of the abearptica of lead, bet it tends to j&$zmms the epgrcaclmte state of the body generally# with - reference to Its wstwell hordes' off lead* . .* * {, Wa&mt the oonSltlo^ of occupational ex^oeuro to lead# it '-'''. ^ 4. ./ / ,-fl -, '. ^+ ". ,.i : -r . k _... ;. .?.. .. fosaihle to devela^ criteria for the eaffefcy of voriaaa# ia of ^s rte . of the urinary' eaccatsticat of leed# on the ons hftndf end the caacentrstica of . r K > lead ia the bleed* ost th oth^r* ao threshold values indicative of . dividing lias between definitely safe and iacipieatly dangcatwa decrees Mf. t \ oc<msaticinsl abeorpti^t of lead ere* approximtely* the eoaw&atn&tioo of 1JQ aierogmae per liter ia ths taiae* and that ef $9 mieto&f&m per 100 jpeas la the wi^ hioM.^ 'v\"''/\ ^ She coaecatratioc of lead ia the blood of pereoes of all' sees is ea edeqmte criteria to dletit^uiah hotveen those vho ere threitcasM idth ^ .'/:; *fc5S< KF 0019256 Jsfc* ****<****** * " * sTJ~hJar * ** * threat*. te& in tho mm of Siifsst* sad$te& children, the eased of ted , ' A,*5 ;\ !?LS poteste hue sot Imm tmxA to <ar ia aosoeletlcaa vith level# of Iced; - eeacantcatte is the blood sate 60 teteft** per 340 gtsas* of shale - - fctesi* A* to that is site by the tra* ted poisoning# or whether there ., W sot ho mm subtle os occult effect erf* iter teatratioa* oat ted la - ; ' '^ ^^ 4.t the body* generally# r Is eerisi* ttesi*a cte * the heels* thsfcteffl^%;- * f -' -^`[oA*t4v. * ^:. set bo Isolate s n o the ayggtoga of eoesiled "classles!1* ted golgCTdsg* so tebt Mtl Mcpsr Is sy *tad* Os the bests of ell accepted evidence there Is little justification for apprehension eeseexalsg s passible haste " ji `rrM.fc of presently ia^s^eehe^lhle type* 0a the other head# these Is jt^tiflcatioo for the coattesA.^ .c es^stoettca of as cs^terasRtal tetar as cesses aad vsriafelft as that of ,- .: > ted* Shis isetal sad Its sees seed to he kept taste sarveiUsaoe so that -:. they er raatlt&e rlth baat&a safety* as specified % seaslngfttl criteria* . M criteria are available ith revest to food aad bcvertitge## ss& euefc * > criterion is being dsrelced vith respect to the s&sosjtee* . It Is possible that fredoab loft tear# criteria sill need refteaset fros ties to that* and if so*. tMs t* ea expected, pro&wt of th* exteaire reseeatetfeat hod to. - , 4 * tt*^ ease to the efforts of aodem mm to tesrstaad end to coated the eavirceawiat .} /' /^ *'VH > '*.1 vhich he Is altering# dr&attelly# to his oim ends* ., T;& astet# of ted lagested vith ted and beverages and the aaount / inhaled ftm the fitaosphare eocistitut the total threat* If aay, of ted- to a huasan fetes* Sower# stee these seate* differ is their tea* sad ease of jeaatmtioa iter' th body* sad* to erase slight extent, is their sftet ; Cpoa the iistrtette 4sd tedli&g f ted ia the body* they wost he essssted*' seBaratelaf* as to jriaatftwBWf, AwtrfiW, the UMt of safety* with msoeet to *v* jjwwmtiwB ct load ***** tfc* ., ntst he estahHahad** *^f ^pj ^pp^p^p p p b ^^v b v `peep mmp p ^p^^f ^p t ^p ^^Pp ^p - ^p ^p . pp^p h MU the fri&fty 1* belns. h*1S aflttetipfttL: b p * *&** *&**.* OM tetp )ufiB the ' object of two greats of steeiisl exsiariaanis &t Kttteriw SiebotAtor?* :^^FBj^^pPP TPBB ^FF pji ^^R^P"PiP^PPPf ^PQPH^Pp^BP^MPlP BPF^HlP TpW^^^B ^PB^BPIPb P ^P ^^P^p f S, ^p X one set of experlacnta, grasps of people v*r .glvas a attasurad - < 55 * d*f7c gusgt&ty of iad $&? day, in #jp^t,^}'f-^fft <j fof* ingestion of good. ocotaadn&ted 1 vtth lead. In brief, they Bata sat sp the criterion ftr safety. 6a the 1 8 < cf thfi&a *>* flrfctyffy jmerlaaiii. It; is jMt.tii*i pteftwMa ffait * wm&ft.m p lp'BF^PlW^BP PF^B^^b p ^^Fpspp^ppp ^^F^^.gE^pPP. P^^PPPPPp Pc ^^PWp P^^^P^P^PjHflk^p Wr C^^B^P wPPPP^^^r PP^^PP j |k healthy feSult can bs expected to lngeat, rtgaljurly, an average quantity of 4 ? '1 ^ft56ss#|fi|ftfe ItffijfifrSH 'i^h^PHPL 0a& ftST* ^t&ST* ft^%l&fiS$t&> ftfifiT Sf'jtjdE, ft? ftCftt2ttkXft&JLfi ft significant <ju5mtity of lead in e life tine. A diffortst sitmtioa arisos, hamar^ S seaanrlng th oaooat of lm& eCmmrtd alo Haar tofiy ty ^a*Efcblag* 9Ml|r to bcgitt vith# cannot be J / *- ^ - ", f*. ? -Ar dirstly, bat taart be calculated froa a waaiber of factor*. Tbe ^eet atisfs<rtory ^siol^icai criterion lies in tbs recpat** effardefl by the i*bapp; In tha cftttfewife ef T<Wf* la the urine aae Mood* Kotfow. while pwftltfpjtp ja*iMde definitive evidence of tbe safety or tto potential riak at the tiae of the analyse*, th^y cannot yield Isfoxnatioa on vhich to preilot the prcbable ifV? estest of the Ohtapticei that vlll ultlmie^ oetttsr vhen ioed ia toiaa absorbed '%? - *J... ^ '--. ,'/ -;'::,;^' into the body at a constant, ai^nifioaat rate* This is the difference, and it ,< , ; 1" 1 a fuadaaaatal pbgreiol^ical difference, batseao occupetlcoal eapoenre on ^ *-/ ' ' ',, //" 8 hoara ^r, 5 days per seek, and coo&mity easpoenre, vbi^ is eontinnoae '. throat the 2b boom a day on f d^a a se^t* si W .!>/ '4| * f '. v-i *;,,S These facts asa&e it mceaoary to sgpjjarooch the oriterioa of peblle, safety, ia relation to lead in the ataosphero, on a different $slaoi$&* than that of the safely of aa^lcyecs in the le&d*eins Indastrles* It is also ,>^4> necessary to esg&cy a different Method of bce*v*tloti froa that ecocoreed with f N'%'-> the ingestion of lead. '-..Cf? 001 258 ...%r ' . Ca ^ - . $` , , V* > -: M m&m way at the Bettaring labcretcary, toe bnaaao stfc^ocied to atsogpbciile lead cettceatraiiocs ef l# nii^pMi|ir: satar^ Stesae ., 1$ l&m'Jmi'taaderisy for a. parted.*^' ' <&.Uv^ Ifcc ^t ^J7 ths saSd subjects hove been1 stadias elaoct half their tlmoJ$ tv?* A veeh la the 'V,<l.;1r` -^ ^*1t U ' 3 *r^- ,, t-.. * 'J*. .~ -i * O-* Mace this oxperisaeasfe has wy nearly ran its eearae* with negative -j* a "tf* . i.'v -i-V'V^W results t far, it msm noeassoar begis tgnln at a high*r local of the ,, . , :7/;-|J ' T -. '. ; '',V c2icestr&tio& of lai la tfea efeaa&er, so as to Obtain barely positive reaeits ' " '; :`V"':- fey which to describe, fey 3ctra^oiatioo caadttlomi* which n potentially -si- -rjt dar^erotts* Seh conditions wilt ho in advsaea of the threshold, of safety, . V::: ,,:; ^ Jt , 7 '' which tb&a will fee located at a lower level* Shit is % -tfc ' ' . . -' hat through ayah wm&kst m mtlefaetcery eriterioa .of jpAU safety cae -ho . ' -. : ;-i'/'' ' .' . *\ P^SgUtL^ , f'V " .. established on a physiologic basis, with snob Margin <ailiBar ho considered . . twt' hc^mUml- m& eagegod ia ii^laaitpiol hysieae aai :'' , '.J ; 1 '. C0tXjO^^ smk aoemotoa tfeKssalve to tho ^ o^ativity is the roowltO Of eto^iar ;lfo oao io lao?ea4 l^ a^sttiv# flMia^i# fact that tl ptfhlic health smt bo (iotorihoi/ la practice, la otieh' tlpai^oad V -.; k e-^ that cafcty mst bo defined as the absence of b&aard, 1 arc (wdtlagfk this Ingtsnco, t a disability mor a diiteo# bat a threat# So each throat has bi ".' . > - --' . 'V/v,. ,-. 1 tsmSt, aithooeh tho setheds ftr di^ostibs it havo timir scnsltivitar* la toms of preeoat iaiNiOi^loa, H-v1 .^*;r '?r.'4 w* f 'ffS vfeich feas bv^a sou^t sy^et^tlc&Uy, tha fact is clearJ> t y.^1 Iareaant bajMird to the public health is reproscatoi thread! ' ' '. -v * dispenwd is the air is association with tho coo of leaded ^aselias* t^ tottvoss ^V v^T- 'r **> : Kr 001S259 -t6iVft*<, i *.- .-' '4 . , ists&e of .'%m& hy pezsooa In the toN:ffepl|* - Ws&smtst, the atrthode of iareatigatton e'raiie&Xe at t eet-amfe-llNfl *& or la %&'V*ad it of the atmosphere, r, for that setter, la tin intake cad absorption jf r, ' '**/. -. sf^portioaa* M F;'- sMttim to this It should % possible, before long, ,to impgil? criteria for reae'caa'blo ctaadarda of air ftssXlty, with respect to lead contest, laUfe will t&fce 1st account the physical and physiological factor that influence the rccplrability m& the abaorl^ility of the eon* peaafi* of lead feasd eomcaly ia the atmosphere# Truly, thia l* natter vhica is esaspler la Itself, a& one which amt be fral/wood ftgalast tb* other stereos of load sSmerptiaeu . A acre satlafaetory |ffocdra ia relation to ps&He safety, sod cm which asset he esglcyed, is that -of making hsermtloes free tins to ti repareseatetiw groups ia the population, by methods which trill. ladiest# .1^ ',' . K" 0019260