Document jmZ9YR1JK53OVbaDgpZaVpbx5

FILE NAME: Saranac (SAR) DATE: 1948 Nov 3 DOC#: SAR157 DOCUMENT DESCRIPTION: Memo from the Medical Dept of the American Brake Shoe Co in Response to Vandiver Brown's Comments on the Saranac Report rv .AMERICAN BRAKE SHOE COMPANY1 C 0 P I MEDICAL DEPARTMENT 2501 b lu e I s la n d Av. Chicago 8, 111. N ovenbjr 3, 19li8. I have read c a re fu lly tha rep o rt you forwarded and an retu rn in g i t w ith ay constants. Mr, Brown's remarks on th a "q u a lify in g a d je c tiv e s " in the a b s tr a c t and c o n c lu sio n s. ------ While adm itting th e a d v is a b ility of re co n cilin g th a two. i t a u st ba remembered th a t any animal experim entation canr.ot be a b so lu te ly co n d u c iv e . O bservations on th e t i s s u e re a c tio n s to v a rio u s substances can maan nothing more th a n reasonably a c c u ra te su p p o rtiv e evidence t h a t th e e f f e c t noted i s what i s l i k a l y t o occur in nan a f t e r s im ila r exposure. The re p o rt n c te s t h a t tb s easts r e s u l t i s no t always obtained I s each sp e c ie s of experim ental animal u se a . i t i s in u ro fu *e o nly p o s s ib le to rp lo y such p h raseology a s , " th e d u st apparently does net a lte r sig n ific a n tly the course of experim ental tuberculosis in guinea p ig s," e tc . P ossibly a sim ilar experiment carried over a longer p e rio d of tim e could produce an e n t i r e ly d i f f e r e n t r e s u l t . There are to o many in ta n g ib le s to allow dogm atic o r more d e f i n i t e statem en ts. T h is i s tr u e o f any ex p e rim en tal work i n animal s o r hunans. The v alu e o f th e experim ental work l i e s in the fa c t th at i t fores a reasonable b asis fo r study of c h a ra c te ristic tissu e changes which are s im ila r to those seen in humans. * Y - -.i > I g ain th e im p ressio n from Mr. Brown's l e t t e r t h a t be i s concerned w ith p o s s ib le re p e rc u ssio n s from th e l e g a l p a i n t of view b u t -I e a s t co n fess I dc not , sea an y th in g in the r e p o r t in i t s p re se n t fo r a which oiaflC cause, undue concern, j i l - l l a r r e r e r ts are f r e iu a n t i n 't h e lite in iC ire 'no t only in tfais*~counOy ~bat c l z'ro:r. aboard. . . . C ertain im p lic a tio n s have been made i n th e r e p o rt such me t h a t r e f e r ring to incidence' of pneumonia among th e experim ental anim als and th e su g g e stio n t h a t a sb e sto s d u s t m igntTiave acme degree of r e s p o n s i b i l i ty f o r such a d evelopednt, fcxrt, th e s e are e x p lain ed and disco u n ted i n t he ensuing t e x t . Ferh ap s th ese im p lic a tio n s rdght~be stodTfled wtmsrwhat pending f u r th e r factu al'* d ata." I f e e l t h a t sin c e mpat _pf J .he b a s ic f a c t s w ith th e ex c ep tio n o f th e more d e t a i l e d e tu d ie s m entioned in th e r e p o r t arm alre ad y known and have been pu b lish ed i n o th e r s tu d ie s on a s b e s to s , no u n fav o rab le r e a c t i o n need b e a n tic ip a te d . I th in k the id e a c l review ing th e m anuscript p r io r to p u b lic a tio n i s a good one in o rd sr t o achieve mutual understanding w ith S aranac, but I f e e l th a t t h i s can ba accom p lis h e d q u ite s a t i s f a c t o r i ly w ithout Mf presence. 1 7N' - 2. Mr. 3rown h u s ta te d t h a t i t would ba ad v isab le t e r u s to d esig n a te a re u re se n ta tiv e of another ooacany to a c t fa r us in connection arit> ths d e c isio n s to be Bade. I th in k t h i s would be a s a tis fa c to ry a lte r n a tiv e and wool-.' l ik e t o suggest t h a t we re q u e s t him (U r. Brown) to a c t f o r u s . I t would be Best d i f f i c u l t f o r wo to a tte n d p e rs o n a lly a t t h i s t i a e because of th e eatings I nentloned to you over the ohone. I as sure our in te r e s t in the a t t a r could be a d e q u ately p ro te c te d by Ur. Brown. / / L* E* Medical Director \t7->-