Document jkmOb9q53z6dbw62q29gvKE2

R & S 113003 BIO-MEDICAL-RESEARCH DOCUMENT DESCRIPTION FORM Duplicate in all cards: 63 68 69 0000401* year as-1961- File number [Right justify [Numeric only] Author(s), as Last Name FS (No Punctuation) and coden for journal as JAMA preceeded by one blank space 1 20 21 M/M TJ-, M7 40 41 77 78 Sub-Index Code 60 61 62 11 12 13 Title of Report; end with space-hyphen-hyphen-space. Follow with Index Terms, separated from each other with comma-space. Avoid other punctuation; do not abbreviate. 12 ^ _ 61 62 21 22 Z-. tr7 7- /?#/#->------------- 23 W/ TWM^I-/)/^ CSVHLC/f. /MrS' 24 Source (Journal, Vol., Number, Pages,Date) 12______________ 61 62 31 32 Brief Summary 12 10 SUMMARY: 61 62 61 62 63 64 frooeu s*u I. A ir . .*_ THE WASHINGTON TOST ___________ ___________ Vinyl Clilorlilo Linked to Cntteer Chemical Hazard Kept Qtriei By Morlun Minis er* of rats breathing vinyl Malionl observed (hot tumors Mny 10. He> disclosed Dial In W,hu>tUn mi Hull Wimr chloride in a ratio of 250 parts were continuing to occur In rats ha had fount) ono liver on- For at least n jwr, chemical H r million (ppmt. rals At 250 ppm, firms In Iho United Stales and That was In August. 1073. At magaxinc says, the trade losarmms nt only 50 ppm, Europe withheld significant that time, the permissible Tho first public disclosure along with other types of tu scientific findings linking level for workers Allowed by of his findings came on Feb. mors. . liver cancer to got used to the Occupational Health and 19, 1074. This was 34 (lay* af For some nine months, a make one of tho commonest plasties, tho American Cheml* cal Buddy's weekly news mspuine reporta today,''"' The gas la vinyl chloride, used to mnko the plastic poly* vinyl clilovltle. The trade association of Iho Amorlrnn chemical Industry, the Manufacturing Chemists Association, ]olncti In holding the findings In confidence, Chemical nnrl Engineering News reports in Its May 20 tv sue. Safety Administration (OSIIA) was 500 ppm, or twin as much. In January, 1079, five months otter Malionl found tho first rat Angiosarcoma, a teixin of three U.S. chemical Industry scieiilisl) visited him In Bologna to learn about his work. The visit Yum preceded by months of ncpnllfltlons with the Europrnn* firms In add) Hn lo Maledlson that Intel JelfW'd Ih; sponsoring lit* ter H.F. Hoodrich Co. am nounred that since 1071 three workers at 1U polyvinyl plant In 1g)Utsvltlo lind died of an giosarcoma of Iho llvcrr Since then, the total or con firmed victims of anfltosnr- enma At (he Goodrich facility snd aI other polyvinyl rhloride plants In tho United Stales has titerensod to 15 and Innthrr countries lo six. Two nf the AmcrlcAn workers sur vive. AH of Hie others have House-Senate conference com mlltee has hAd a blU before It that would require manufac turers to test new eliotnlcals under rules laid down by tho Knvlronomrntal Protection Agency (KPA). The stalled legislation Is the proposed toxic subitancos con troll bill. Senate conferees hove hern wMtlng for llep. Harley O. Bloggers (O-W. Vn,). clinlniian nf llw House rotifer rex, tn onnomire Ids readiness The Italian scientist who studies: Imperial Chemical In died. tn meet, Brnsto sourrrs any. made tho findings M(d that al- dustries, Bolvny and Hbone On April 8, OSIIA an The House but would re- though preliminary, they were Prngll. nounced an cmergoncy rule quire pre-produrllan testing of 'prcdU'tiVQ'' of the fatal can* Out "CJi. chemical Industry drastically lowering tho per only those new chemicals that tors recently rccognlxcd In sources say they were bound missible concentration of vinyl arc Hslod as potentially dan several workers employed in by an agreement under which chloride from 000 ppm to 00 gerous. with results to bo re converting the gas litlo polyvi (thrl four European firms con* ppm. Worker* engaged In ported to the 1CPA DO day* be nyl chloride. trolled any release of animal manufacturing vinyl chloride fore production is to bogln. The sciential la l*rof, Ccsare lest dam obtained by Prof. and polyvinyl chloride number 'Die stronger Senate version MaltonI, director of the lusti Malionl,** Chemical and Engl 8.500 In the United States and would require* In addition that tuto dt Oncolwda In Hologna.t peering News says. II did nut-20 000 elsewhere. companies noilfy the agency IInn aS satltukdiluy IInStiltlliaalle^d.l tInn dS&cnplikeam. -IiuMnnumaaci annuyll of IthLeu. AI meric.a. n1 IE'tHvSenn IthKojf 0R0A Mplpm luvel may of all now chemicals consid bcr. 1071, by one of tho Euro- llrtns. be hasardous, Malionl told ered Tor production, so that pean firms* Montedison, ho A key second experiment at meeting of the New. Vork the EPA could order testing cl 3 tdicovefed a rare fern of ean* levels of 200,100, and 100 ppm Academy of Sciences and the chemicals that are not on the ? car,'. anjlorcomi; in th* llv- began aboutJuly 8,1872, whtn American Cancer, Society on list but that may be suspect .ailf It ! I W-.