Document jgrbORKMnGB6gXo5b612e3Qy

Industrial Hvfllane Digest Aumit, 1961 and cholesterol. The moat miking finding w| an increase In.phospholiptds, rjrtaximum at about 2 week* iftir injection of Quarts* both in Iha peritoneum and the lunge* As a second step, phot- phoUpfde were extracted from pulmonary allfcotlc lesions andre-injected intraperitoneally In other animals, Despite repeated injections for 16 days, no peritoneal lesions mere found, the only abnormality being a splenomegaly. -- AFCA Abets. 754 la There a Relationship Between Silicosis and Histoplasmosis? W. 9. Cortes, et *! Diseases of Chest 41, 645-o51 IJune 19621, 1 "* * It Is probable that there le infrequent coexistence of chronic pulmonary hlstoplasmoels and ellieoeis* Apparently, eilicoele has little effect on benign hietoplaemoeU, since fewer pa tients are admitted to the sanatorium fr6m an araa of high eilicoele incidence than from other . .arena. Jt iettrusAhat^hie Is.xdaaam icrpa.iafjaJ--oao*ate of"hltoplaxmin-akfa> woaetivtiy. bat the rqte is still high. Further determination of 4he posaible effect of eilicoele on t|i progress of chr^onic'pulmonar)* histoplqsmosjs will depend on a dUigntssear.cb for the accumulation of 4 , . f^lldw*Hpd4ia<dh miny more'casey-such ar'erq prrtbQted in this paper. V, . p . 7.'* . lt* /. . .* " \,t \ *............... ` 4* * *'** . ** .* \*.Au*he' seclusions. rtt The.CohaWtufiOnal Factor In.Aebeatoaia, . H.* Bohllg, C.. Jacob and. ft. Muller.' 'Arcb. QfwcrbeprthoU Gewarbahyg. IQ. 596-609`(1961). Carman. The possibility of individual, family et racially conditioned susceptibility to certain dlteaeee haa tong baen discussed. It has been considered in relation |o eilicoeia in a number of papers (Bull. Hva. >0. 378 (1956)) which ere mentioned end discus'ssd in the present peper. In asbestoeie, however, because of there being considerably fewer industrial concerns in which as bestos dust Is a risk, the literature is sesntier than that of silicosis and vary few instancae>of asbeetoais among members of the same family have been reported. There are given here de- .* tailed family bietoriee and clinical particulars of members of 3 families--Z brothers in.each of 2 familiae and 2 sisters In 1 family--all of whom suffered from the effects of exposure to ne- beatoe in the course of their employments. In addition there Is a description with many refer ences oi the morbidity of aebaetcale and Its relation to length of period of .exposure to asbestos duet at work. The records of the 6 patients in all of whom x-ray examination showed definite eabeetoeis werat (I) two brothers died after 18 to 25 years' exposure to asbestos, one of bron chial earcinoma and the other of a pleural tumor) (2) two eietere after 32 to 35 yaara' exposure were alive, aged 84 and 82 years, but had shortneee of breath and bronchial catarrh) and (3) two brother! had only 3 to 4 yaara* exposure to asbestos and were alive,at over 62 years of age* Both of them suffered from some shortness of breath and cough. On this evidence the opinion expressed le that personal constitution plays no part in susceptibility to, asbestoeie but doee in fluence the progress of the condition. -- Bull, Hyg, 3 156 The Effect of Missive Posse of Vitamin B, on the Pevelopment and Course of Experimental Sili cosis in Albino Rate. M. 1. JUsuniov, B. K. Skirko and 1U. Srubina. Arkb, Fatol. 23, 55-62 (1961). Russian, $ < This Investigation is a continuation of the work in which it was shown that only cry stalline forms of quarts are dangerous from the viewpoint of silicosis hasards. The following hypothesis was put forward: dust particles interact with the pulmonary tissue dua to their pleso- electric properties, Ae a result of this, disturbances of tha tissue metabolic processes take place leading to the development of fibrosis. Sinco riboflavin takas an active part in the redox pro cesses, experiments were staged to analyse the effect of large doses of the vitamin (250 micro grams) on the development of experimental silicosis in white rats, As shown, administration of riboflavin In largo doses to silicotic animals accelerated the development of the pathological pro-, cess (the fibrous foci In the lung formed earlier then In control animals), *' * (Authors' tleh Summary) r-APCX Abets, t <