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nto L. G. S ch arp f, J r . - NlA February 18, 1976 PENTACHLOROPNENOL M. C. T hrodahl - DID cc WJPD.... ASPB.... 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LGS/dc A ttachm ents L. G. S ch arp f, J r . V "dd.n, TI iteeaide3s. nieaCnnaleOdnsted 58 Monsanto * leCATrOf* W. B. B ennet/D . P. Roman - NIA o*rc February 18, 1976 i/tii'-.r PEENNVTIRAOCNHMLOERNOTPAHLENSTOALTUS TO : L. G. S ch arp f, J r . - NIA cc p PsJPJE....... HAPLSEG....... WTMMVHHiaoeireemegintrguecdnnhlraereetrilykf se ------- ABBBTN1227232INANSSF4CCAC0 1. Background dodiCdtPnhnieiiobsbeenmeaesetenmaonnaiszcfzemeehoorc,tlf-a-hifpoplaeaesr-l-ndcoddlrpgitieeoshorva.ahxexdnesiiinsoeanttlslsoec.tpdooheaxannTtvjtithhcoeehoyaensmbltto.epewgesrmoeinimdcdbPoeefeuorsamsrupul.iitnrnfneidetaeoraEnadwdttvotaiapduroldsceiunoeonasxentt)aaifitnncsfagewhincaileosptrswreueooponpoc(ctadhcattoacuhehcpnsloehrl2ooder5lloras0orbce0dopryniddvhpeapiec,bmtnnhiecoolvnohctlezhir.cpitolnokor-oapxrdtei-iendudcdeaciimotteyexadin , hanaTteltaehotttererenbandgbicctahiwidsodliioinebctrhepmon2dnaz,io4obcltd,eeho5inc~eonzTuxcoeliidaansnneristo'd.isxrsteuriinmutTscshmpte(auTeprCmcryreetDorsouDseoftm)nf, ctthoweodexfiabsiincedtondioxmzitshxoieccedmioonibvloseeoe.nxrgrvienyoidrfooinsaftmhs egtehainvneftaenmhifmaaimsilpnyiu,flryoFic2tiyguo,3usfsir,ne7ecdh,8t1lh-,oeri Tdmknihaooewnxunpinfrasoocbrtcauaobrsuilsneludgmmebcodeodenftdoooirftmbioeefndosprmfrreioassmteionshnltoowwionnef r cOinoCcmDhDFlmoiger(iourncrciaetatalec2dph. elopnLrhtaoee-sndasoirloehsx.igisnhho)OlwytunhcneihdrneloirmFripipngeuauntrrteiaetdie3s. 2. Environmental C onsiderations nfTToeriCeCxensDDagplhyDDdeacitsilii(tnysvleaondewsd..stauolkyHspieAplrosnodeswbect hguati.apdberanaeldybalvyeyliydolyspptehiulnsaetbrrnlestitoacsodti,iiezoeledssxsdu.tianwbbsfjii)Detlnhicesdwtshihanpsteigoirttebfsoopiucfthhnipoddelrteeesossesdteosenpfcocbtorhueoemnapndpiiemnorofsmtwaniiteoeriisbolinpldlepee,lbsiffspfienoienTrrChtssDsaVoiDvsiietteloesttnhnb,aaeftmniennnaoednstde Pdieendtawchitlho rosypmh epntooml swoafs ef xi rcsetssiivmep lpiceartiecda r dinia 1l 95f7lu iwdhen(" cmhiilclkio nesdemoaf db irsoeialeser s") 1 ?2 SUBJECT TO PROTECTIVE ORDER. &TJTTZ- O 09-74-6 C1903S FLe.bmG.arSych1a8r,pf1, 9J76r. Page 2 Cc(hfellerotsrahoipninhgefeneogdlrepaf asreetsss)ewrvreearcetoivvimeerspe. ldicfartoemd haniddestratcree adtetdo wb yit-hp rot rdiu-ct antadllpoewn ta - mdrCeioeoannxdtciienblrynsu t rhientadhtsouiscbesedheonaisltoenfxrtopohtrmeebsmespeeeondnretdtahte-oamtrxteoiacOntCseDhtrdDeaxtwe(amdoco.hadljooMprrooeddsaitigosbexergninrizveoepidnoinorpextseginnaottaniivn) emmthifgiiegnrhadettiinonbvngeirsoo. nf 3. Human S a fe ty mdHctstrrhCeheeeoDpldawaoDatitrnrcmiat(anmcheilgnneneexrnteaoatc.nacipnohiremerlrdohaasucrltomiooa-tnannednfdsssilo.tiscIexnntiiMgtndnoa)uogg,nse.cstdwarauinhTaistinocelhhehmci sShiyasPlgnoAiiunrpeafirnascetcehnst-eceeupo.nrrpentardcoRaiuntncecidecptcsieonosusrgms-toesimnafooesefftrhucxirpeaianvmelecaniyipentdaneienonungiftfncaeweI,cwtotsuohoodaofrlosdnwgbneen 4. A nalysis of Monsanto Penta phdAdaLaci sbarinioinbooovmoanaexeuplltianlyittieynentztsroitds1ouitinsi5cfaeguddd,alsblrlaae)yayn2tttaene0toe0iescsnscn.oilt-nheaanopnccanbthNdetvoilerqepouanou1e5rionei0li9rnlna-m0sp7icfbc0roiaoopl.ftreppotudcmemotrruduemT.acxprthttpehaicireooonoIeennnnppGdemeCttruneopesctirnwttssentifhe.nmoeieb"nttrryhapyateHctrnaiebacioeocnrl-oexneuneddnsa'msskiitf-tocon,iiirfnxatoit-muneahtiwenceteahnhsmsncpt"eonitatoslntiasuoqnols(-meuoovbabsTnerf npCeyeDdetpclchDpmcheootorernnaroeafcitsosmnarsstmidaecsap-hsnhtetdpsnoaotltoivro.gesoyoecrrsaxiptfinrpbpiceonhahrnlseosytaccencaodgaaet-ponder eddyxu .irce 5. Dioxin Removal bplDayeitroirxoepinnocsurwnydcosa.utnaldllbibezearethimiogonhvedo( er fsrbtoy.md$8piMes)nt itlaalnad(ttioaodndaep. dp rpCecrooisadtbulocyft,ioalensdsci os ttshitlalnwaot3ui0oldnppbmei n 2tso0t a-t2al5l) 6. B iological Tests pPcsrgsheaheerosmeninpwcattpkoaaetlndeehsrsegdeaniesvot(mhelianaasarnbneLspttphecDaooonesjsdgnutisrsltdiaeopvb.iflneabben2iT7rttt)eh0ahsceaepchmatrooeargnvuC/esknithseegete,sshdrtiionen.hwsofponrcwoaAhrenltivocsbnsewkyeu.rm,eeftrbhodaAeueerrtmneddsodalipefsiovoftteoixenensxrislnsctepisc,tenobrgmpebdimluiromseatwecnsenrdeoretcntnapihpltalaye.lolnysclpdieypteiitrnsvhoittednaai lullwcateehcdaddneoses e pp ee nn ttaa C O h r ijL>iC.i.N" i I A L v'-n ^C T TO PROTECTIVE ORDER -trrjTTT-^ C9039 LF.ebGru. aSrych1a8r,pf1, 97J6r. Page 3 P o litic a l Climate hbrtgddsEIcoeaneuaeienmqoatvrnsvputexlpeeoivteerirsihoebonnstatenntri-tleugihaclmmydsa,otaihnhevntpnrieteitvhlettsatiascheenincilnoneoaecgSeiJtggtnicoeWncraoogofuiitnozneauiirvueonsstpnhhdnmecsaeidoecnlriciftobafgsoAiirnitmntocueitdmdbnias)vdeiieip.pinnnePsragossaoecopHsfbrstsysde(setaiooen,einnoBlf.utncggta1xoettecl..-,airi2bnalrnnodya5tnsehauE,-cd7oePtdtfeioAu6utlvlhyEa,llroelirPbI-neuAsbopfpvgvgoveaaiohcIersergosop.ttwedlbnetyhutnaceePpatnnethcafrdnerrunhehetnienneionisrtcgdagdhneiqphleeredauavil2aoysbeal,lbuort4stiheyi.tstut,voaiep5tcrexht-lrhTbapesEaieceP.ztlaedeAaansnTpFritdCwdbhsuarDysea,n-iDsdodsthsactithonhuhIfdseoxreaerrrigne, d ppDtypdomp.wseeC(mnohofeaxmmp.)ircoaabttleolerhtmiaaasll.i fdcoioOumxstmeihneesirrscpaianrrloedidzsehut rdacisecartsuedrdgfieesdettoillElwPtehAodaodttopttehrrneeetaasctttyihrnpliogcertoofpopfhrroednodioouuxtlcditwnoiosointrhInuto3s0pete.hnitsa Research Flans Ra neaselyarscish wanidll bcioolnocgeinctaral tete os ntintgh eoaf remaisnoor f c Ionndsutistutreina lts haysgiefonelloawnds: th e a . mTphheeeansnuoarle,tus rpereencatonamdmaneedxndteSednant tiofopfhneheneedaeldt1h; upnriotsblewmisl,l bi fe afonuyn, d inandth ep recvhelonrtoiv-e b . oPf ouerrntapinrdwe siivelnildtubaeanl sabelpyioati-rcateatesld/ttionixgnitcoion lpoahgneincaotatlleicmcapontrdrteonlaoctnil-oapnrhisef;nyo lalcnocmoamlipeosneinnts c. sTctaohhmelboptreleeitncsthaentfreoiqdridu edetolnbxoteiiffcnyozliolqomfuugiirnidaconarscl )hcotreomasmnptdoia,nntoegtgno;rtsapthh(epicaersxteitcepunatlraaprtilooysnss"ibpwrleei,-ldl piobrxoevinuidss"eed and d. pDhioenxoinlss caonma lpylseexs wwheirlel bdea tao bntoawin eisd afod mr iattlel dplyro sdkuecttcsh yfr;om the c h lo ro e. Sfroomme terfefaotretd wwiolol dbein teoxpethndeedsuorrno uinndviensgtigs aotiilo; n o f m ig ratio n o f d io x in s f . Manodnspaontsos iwb liell ropuanrdti-croipbainte a inna lgyotvicearnlmteenstticnogm. m ittees on dioxins re se a rc h CONFIDENTIAL SUBJECT TO PROTECTIVE ORDER. 0 33 ir 7 u-- Q4 9 74C3 19040 FLe. bGru.aSrych1a8r,pf1,9J76r. Page 4 Tmishaenuuenfcdaoecnrtouwmreaiycosofnopf aeSnpatanrotocfpreohsmsen"bto1y -lmperasonsdeuunfcatcstthuoirsef bdtheype-penSrodadnuttoocpthaefonmramprkraoetdicoenesxsa.tepnpRtreeocsneiaabrclhy . tf. B. Bennet D. P. Roman / dc v i N r \l r Si-Id A. 1 UBJECT TO ? 7-7EC71VE ORDER. -*3 3+ GO& )7 't4 <PtrP- C19041