Document jNjqMV6EKGYwOGgkkEdNLQZB5

DOW CHEMICAL U.S.A. 1803 Building 22 January 1985 MIDLAND. MICHIGAN 48640 W. Clark Cooper, M.D. I. Tabershaw, M.D. C. Tamburro, M.D. . 0. Wong, Ph.D. ANGIOSARCOMA REGISTRY Dr. Brian Bennett of ICI has revised the angiosarcoma registry as of ' 14 January'19851 See copy, enclosed. There appear to be- no major surprises. It will be interesting to see if the apparent reduction in numbers since 1981 continues in future years. Sincerely yours, Theodore R. Torkelson, Sc.D. Health & Ehvironmental Sciences . 517/636-5197 cc: Dr. Bennett, ICI Enc R&S 103074 AN OPERATING UNIT OP THE DOW CHEMICAL COMPANY i4 DOW RESEARCH tM*J t'ACK SZO0OI- S9U NllWiAUXittlEHTS,* SIGNIFICANT CilANUFS AND CUHHWJ'i'S *' i , 4. Tito uuu cases in 1 lio Register uru the following : BelgiumV 02 UK * 10 usa' - 37 usa` ; 38 A. . ***' . * It should be no led tbut there are corrections from the previous Register ugainst the following canes : , '' *, * *V Prance* ' 16 UK *' > 07 i USA- v 1*., 13, 3*t, 33 I would like to thunk John Barr for the. Plant corrections 'that are in that Section. 1 uutild like to thunk Or. Be Sloover, Or. U. H. J. Williams and Ur. M. N. Johnson, together with Mr. John Barr fur informing me of new cases. . . - * Por tho cuse corrections, 1 would like to thank Dr. J. C.Oontassot, Dr. U. *Ji. J. Williams and Ur. M. N. Johnson. . t: '* * 1 would especially like to thank Ur. Joyce A Salg for.the great deal of effort which she jiut into clarifying USA l1! ond 13, which hud previously been .documented as dubious fabrication cases. . * 0 1 should be very gruloful if all the recipients of the Register could coutiiiue to keep me totally informed of uny now casus or, if they should hear of other Companies whio have acquired a case of ASL, it would be much uppreciulud if 1 could he informed by the appropriate person. With rufurence to the Hugister format,I* will be continually trying to iwproVe it. r * 11`I- ** * . jinutt Jan i*j8'> jiiiikj.u. untili:ai. j ami n.tatict division I.IVEH Augtti**r.:uaa* C*** - (K*vl*w 0*1 *l .1 Ja 1495) Mum I 1 ' I I---------- 1 I r ahii | haiik im r.MCE j IHITUIS uArae oa I I MW j I .I I.. I t I IS.II.ti | I I ........I......... I la llb.UI.lt I I I I---I til lb.IIS. 1* | 1 I I ..............I US.<14.14 ( I I I I....... I------1 u> III.US.II I I I I.....I 06 IS.12.14 j ui I IM* ---------- 1 il4.ll .14 | I I I IS.US.Ill I 1 --I 0!# 1 I4.ul.il | II l l.._. .i ...............J... (Air by l*r fr UfcMUtHK Ih Aimaile* i* 1i lS14 I - h1 I 11 FACfUHY |11 1 tl*sr vc KKFOSIIM HATH. IIT t AUK At Ilf ARNUSM j 111 ARHUS IS 1 t M11 llWW t \ I I1 . I 1i 1 l | 1944 1 I 11 l41 1411* 14SJ 41 41 ifam inr mhwoke m DIACMS1j t 10 i M r i u h--[ MAK* IN' | DATE (If j HMTIlUKilCAI. KXTObllME | IHIATH l CflM'MHAflON II t-t I lI 11 II |01.09.55 | lM It t-" 14 14 111. II. 51 | I.. I t it 14 IS lb RST1HATF0 I i omit KIHUUflte I OCCUPATION | CAkEKK UtVtL | j B1CHUCHT9 j | | OTIICH CdtWEHTS I I Ituctw jitaauar II I\ |0|Hflor |9ulii jpolyMi I Allan | iHclnloMiic*, |Opur*tur jalllvrl|lit, jplp(lttr jlfarkad jovarlla* jlKilir I mi I I I- I| !I I I--I,l 1441 1444 1461 1461 I46S 41 41 II It 10 21.01.61 j I 11 22 jll.Ill .40 ) II I1 II --f------V 14 05 |U5.01.69 | Iw Ii I (uparator, i jtlurkaj IiiimIIm INoh-mdUi llliEliu |danr | | laactur lUaur joiiiKlu, |Uurkad |twr*MU, |uvartlaa |u( cMlIni jBaukac juJlIA i I----------------1----------- |ll<lf cuollup jHuikad |unlt jnaartlM 15a.uk at 1441 1411 II 14 11 j10.04.11 )M I I Kaactar jclauuar ( HaJt a.imuea, jalllurl*hl | (Uorkad jaaaillaa llaakai 144S 19)1 1) -I--I I mi 144b 19)1 -----------------------1- 14)4 S) 1) _L .L M IS 114.11.11 | II II i---------- 1 II 01 in.ot.n | II 44----------- 1 19 I 24 (04.09.14 | I II I II J_____ J_______L la* la* la* |(ti*dui jcttoaor | jHrchlai <bof |WorfcJ |ufrtor juNrtlM Jpoljr unit jsukir j ( | 1--------------1-------------- 4------------ 1 |onetor clanr ftaltttoaouc* |)a plant 1 |McUn olutp |25 yt*l SwAwrl -i-------------- -i---*I Furuoco op* | lUurkaJ | plpo liur J jlaafllaa | uitotitnouco | (Sawkar | _______ L .1__________ I iuU tMrl#, 1!I7 Vol 21 No t ppt05-|16 cloltpo tHU cnao tm4 both bopotuM vnj ML olnoltoottwoolp* 9JL0S0V SSH ZZOCOl SSfcl table 1 (Review flats - 1 Jan 1985) fun I deuce uf AS). Caeca I'ur Annum 1 *J?>5 6 7 0 9 1960 1 2 3 4 5 6 7 II 9 1970 1 2 1 4 5 r. 7 8 9 1980 1 2 3 4 N.Bj Ity tinte* of death 1 '0 1% 0 0 . ft 1 1 0 2 ft 1 J 5 3 2 3 5 7 C 11 11 0 10 .5 11) 4 1 7 __ 3 Total _1_0_9 * ** I lines mil I nr. 1 inle Italian 01 Imt does tncluile German tl3. ** 2 Ttie 1977 total Includes 119 ease 24 which is a Choi a ng;l osarcoma. I The 1982 total iloes not Include 118 33 who is al.ive and F 15 who is alive. 4 T 983 t oi. 11 tinea not Inc I ml o 118 36 who la alive* Page 29 Dlstrlbut 1 on of AS1. Canon by Country USA W Germany Prance Canada tfK Sweden Yugoslavia Italy Czechoslovakia lapan lie tg turn Norway 35 .*** 21 ** 17 **** 10 9. 5 **** 4 ***** 4 *` 2 2 .. 2 l T.ABLB (Review Date - 1 Jan 19R5) t t Page 30 \ Total 112 t. * * Omit ItOl - atypical case of PVC bdg extruder. ,, -* * *' ** ** Includes CKO3 aerosol can filler. ' *** Includes case US 24 which was diagnosed as Cholangioffar^oma* & US 33, and 36; and F 15# who are alive. **** Include*! one monomer worker. ' * ***** includes two monomer workers. L.e Western Kurope 59 . p * ** , * North America 45 "J. Rest of World 6 Total 112 ` 8Z0&0l S9U attorn of ASL Cases by Factory a) W Europe 6ZO0OL S'SH * * *. r tabLe 3 * 4 (Review Date - 1 Jan 1985) Page 31 Of the cases, 59 IB cases have ocIncuWrreEdurIonpec, lu4s9tehrasveaot c4cufrarecdtorIniesclus te* rs.at 11 factories. Of the 21 German * *l ASL Cases * Dynainlt, Trolsdorf Chloe Chimle (Formerly RPX- St Fons BP, Barry Kemanord, Sundavail \* * .*% . * * ' , % 10 * 8 7 5 PCUK, Brignoud .5 Hacker, Burghausen \\ 4 CWH, Marl 2 IC!, lllllhouse .. 2 Solvay, Tavaux 2 Lonza, Waldshut 2 Solvay, Jeraeppe 2 - * l1*f*".. *9 *4 * li: There ure 11 pre 1962 PVC plants In W Europe; 18 of these*have had ASL coses (Ref Table 8) b) N America * * * 3- Of the 45 cases In N America, 38 have occurred at four factories out of a total of 49 factories - in N America 3B plants have not had ASL .cases . .* * ' ASL Cases BFG, Shawlnlgan BFG, Louisville IJCC, S Charleston Goodyear, Niagara ** t*1, * t 10 14 10 4; 38 4 B: There are 29 pre 1962 PVC plants in N America; 11 of these: have had ASL cases (Ref Tables 9 & */ 10) c) Rest of Uorlil . ; V', The B ASLT.iiriuti are hel teved to lie hi 1 cluster ol 4 arid 3*clusters of 2 castes. - I .. | i| '- I J \ 1 ! : -