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Sr aD E. 1. 0u PoNT DE NEMOURS 5 COMPANY WILMINGTON, DELAWARE 19898 (carbon copies Listes on page 5 AR R86 1494 - TOXICOLGGY AND INDUSTRIAL MEDICINE May 6, 1981 g5 g33 PERSONAL CONFIDENTIAL &H 38 3 55 MEMO TO: HP.PD,E. MOSNETRCEHNABNEITNZ 642 Z5 7 3 FROM : BC.. WF.. RKEARIRNHH,ARDMTD,, MEDR,D", CNRE-D1,140H0ASKELL :CAA Yi FC-143 . Tp KReafme.o:nriCuFnFReilnhaurdct rBoWKacrrch ttCo 3HaE;SneCrAecSm-b3ea8t2zt5,-7e6-;1) "EC-143," dated 4/10/81. - FC-143Thecaurseefdereanbcneormmaelmoeydeesclreinbseess ianpirlaott festtuusdeys.by T3hMeimnemwohich jroebcsommwehnedrse i"tthahtaswobmeeenn dofemocnhsitlrdabteeadrintghatcaptahecrietyisbeporteemnotvieadlfrfoomr bexapcoksgurroeundtoleFvCe-l1s43 (a0n-d0-4bloppomd).leAvrelesasowfheFrCe-14t3heareemplaobyoeveesdehfaivened wblhoeorde tlheevelasirobfornoergacnoinccenftlruaotriinoen oifn FthCe-14b3ackigsroiunndcomrpalnigeancaendwith pourresepnrtovinosiosniaglnifaicccaenpttabrlieskextpoostuherefleitmuist."of 0.01 mg/m should an imOprriegciisneallmyeasweureemsetnitmatoefdtbotlaolodocrogannciecntrfaltuioornisne.of TFhCe-14b3ackb-y , ignrgounitd cionnctheentbraltoioodnofofWiolrmgianngitconflouofrfiincee,wdorekteerrsm,inewdasby0-0m.e4asuprp-m l(easvelflouforineFC)-:143 Situsbeslefquweanstlydevaelmoeptehdo.d foIrt miesassuernisnigtivtehetobloaobdout 0l.e0v0e4lsppnby e(i4tphrebr),metsshodflwuooruilnde.giveItvwaalsuespreisnumtehde sthaamte braacngkeg.round cHaotweevetrh,atitnhietiablackmgeraosuunredmelnetvselofofWibllmooidngtFoCn-14o3ffiicsebweolrokwertshe indihlaesvelaroifsendewthecettihoenr, thtehataccise,ptalbelsse bthlaonod0.l0e0v4elppfmo.r fTehmealequeesmtpiloonye(es200(40.4popnpym) - should be lowered to the detection level of FC-143 EID095478 g TEN THES FOR GETTER YING cru TRS SHERI = 3 . PERSONAL CONFIDENTIAL ] H. E. SERENBETZ -2- May 6, 1981 limiteWde. advise against this step because our information is 1. rTahet eisvidienncconecltuhsaitveF.C-14T3eraistogaentiecrattoegstesn mienettihneg acunrdreDnutPosnttandaanrddsreasrueltsbeisnhgoulcdarrbeiedavaoiutlabblye IbHy Q3-81. 2. dEveemnonsitfratthee ptreerlaitmoigneanriycit3yM, sittudyisisinaasdseuqumaetde tfoor rseentttinagnimaaclcepsttaubdlieesezsphoosuulrdeprsotvainddaerdas.basiTshefocrurTehsetabhluimasnhmednattaonfovacbceeipntgablceollwoercktpeldacsehousltadndaalrsdos. help in setting standards. 3. aBnedcaufseemaloef rtahtesuninusutahleirdirfafteerenocfeebzeotrweeteinngmale mPaCn-.143,A btehetterratmomadyelnoits bbeeintghesobuegshtt.model for : 4. tWehatneethdemabnayckgmroroeundmealseuvrelemeonftsPC-b1ef4o3reinwethecapnopsua-y lation of the U.S. women is leas than 0.004 ppm. 5. eFnCt-14a3dvehrassebeeefnfecitnsusien fhoumrandae.cades without appar- not beWe crhaencgoemdmenudntitlhawte ouharveacmcoerpetabdleefinbiltoiovde leivneflormoafti0o.n4. ppmWe Tshheoulddepahratvenenetnsoughhaveinaflorremaadtyiontakfeonr aSigdneicfiiscieonnt insteapsferwomotnotwhesr. epxopsosuurree, toshFouClMd3n.ot Asigfnewifimocnatnhtsl,y peaxrtteincdultahrelyhawziatrhd olfowearesdubstance that has been in use for many years. i: our cJo.nclRu.s.iGoinbss.on, Director of Health and Safety, concurs with CER/BWK/bjd - i EID096479 3 a-------------- 4 Co PERSONAL CONFIDENTIAL H. E. SERENBETZ -3- cc's to: JW.. RE.. TGaitbusmo,n, AdAmdnm,n, D-D9-0960458 F. A. E. L. DFardeen,ch,F&FJ,r.,B-C22P0,%.B-17249 A. G. C. A. Haven, Hapka, LInetgla,l, D-B3-01437373 C. J. C. T. SGmriitfhf,ithP,PD,PhoDt-o1,300R8SQ-210 J. R. L. L. RShtoodweesl,l, FiPbAr,, DN-8-1414248 H. B. E. C. MSciKmumsoincsk,, JrC.R,ED,CREHDa,skeDl-l6036 J. G. Aftosmis, CRED, Haskell May 6, 1981 . To. og z EID096480 s