Document jNE93GjmprKg9oJX5VYjdp81Q

 National gasotine lead use is not a valid index of exposure at NHANES HI sites Over 50% of the apparent blood lead decrease is attributable to demographics v 5 to 10% of the apparent blood lead decrease is attributable to gasoline lead exposure The blood lead decrease of 0.3 to 0.6/ig/dl attributabte to gasoline lead is consistent with the observed air lead decrease A significant blood lead time trend remains after accounting for demographics and gasoline lead exposure TEH 0532601 i DUP050033869 Gasofine Lead and NHANCSH Wood Lead Levels TEH 0532602 DUP050033870 mr-*nrr$ None OEM DEM. GPb DEM. GPb. GPbao DEM, GPb, GPbgg, Gf%s DEM. log GPb DEM, log GPb. teg GPbjo DEM. log GPb. tag Pb^D- log GPb log GPb Blood Lead, fjg/dt Remaining four Year Attributable Darrein tO ^ 5.80 1.62 127 0.35 1.21 0.41 1.19 043 1.48 0.14 1.10 0.52 1.09 0.53 5.17 4.93 i 0.53 059 0.59 058 0.57 0.60 0.59 0.20 021 `Dependent varuibte Pb. siautsw*igMea by t.'S>noBPt> weight*. <1:; . . ; TEH 0532603 DUP050033871 TEH 0532604 DUP050033872 TEH 0532605 DUP050033873 TEH 0532606 DUP050033874 i;liivA ft:ftif!ftftftftftftIftiiiftsfts 1 ! 1 50 ine Lead Density ////// National OasoUfte Lead Uaa Lead Density TEH 0532607 DUP050033875 lAtei Hwcim Sampled and NHANESI Mood Lead Levels TEH 0532608 DUP050033876 NHANESII Assessment of National Health Status February 1976 to February 1960 64 Sampling Sites 6 Months to 74 Years of Age 27,801 Persons Selected -- 20,322 Examined 9,936 Venous Blood Lead Levels Determined Not Designed for Chronological Trend Analysis Apparent 37 Percent Reduction in Blood Lead TEH 0532609 DUP050033877 I f Analysts__J Adjust for Differing Characteristics flndtvidual Subjects fitter Adjust for Differing Site Characteristics -- With and Without Gasotine Lead ftMMty Unexplained Hm* fiend Compare Unexf^MlfMl;l^Mi With and Without Exposure j TEH 0532610 DUP050033878 anasop"*TM WtewidtfiBPb 2 iTmI iVQ*kif: #P WwsCJ Pm|Xib} kjkjij4:^frif^iiriiilHi:irt',ifivit Wpumff wJlpi.lrTr.AwMM4l <mVmtf gMiy dnd their logarithms With and without BPb weighting factors Residuals Weighted according to 1/S* and N 2 2 Number of models = 2 x 27 x 2 x 2 * 216 Consisten t results regardless of BPb weights, residual weighting, and BPb or In BPb TEH 0532611 DUP050033879 0012 j$ lead Contribution TEH 0532612 DUP050033880 TEH 0532613 DUP050033881 QwoHne Uaagl lExpoiW'g National iSite Density 0.8850 0.0022 0.0019 <0.0001 S 0.0001 twm*. TEH 0532614 DUP050033882  Water MM Oust Characteristics TEH 0532615 DUP050033883