Document jBbEDKqm153z5JRqxab8Ekp92

DownloadRandom document
AR 226 _ 0763 TOXICITY TO AQUATIC PLANTS IESTsuBsTANCE 0000 Identity: MreifxetrurreedctoonatasiPniFnOgSp,erFfCl-u9o5ro,oocrtaansesaulcfoomnaptoen,ewnhtiocfhFmCa-y20a3lsCoF-bXe or FC-203CF. (1-Octanesulfonic acid) (CAS # 2795-39-3). Remarks: The 3M production lot number 203CF. Current information indicates it is a was 101. mixture of The 1% test sample PFOS, 20% is FC- dsioedtihuymleoncetygllyscuollfamtoe,no1b%uttyrlieetthhaenro,l7am0i.n2e%, 2wa%tesru,l2fo.n7a5t%edAcarlkyyllicetfhoearmesrai,ts3,%and 0.05% tolyltriazole. The following summary applies to a mixture with incompletely characterized concentrations ofimpurities. Data may not accurately reflect toxicityof the fluorochemical component of the test sample. METHOD: 000 Method: OECD Guideline 201 Type: Acute Static GLP: No YSepeacrisetsu:dySepleernfaosrtmreudm:ca1p9r9i1comutum Source: In-house culture. Originally from the Culture Collection of Algae at tEhleemUneinvterbsaistyiso:f TAelgxaalscaeltlAcuostuinnt,sT(ecxelalss./ml), growth rate Exposure period: 96 hours SctoamtpiusttiecralpMroegtrhaomdso:f SStteaptihsatni,cal19a8n3a.lyses were performed using the Analytical monitoring: pH, conductivity, and temperature Test Conditions: - Algal Nutrient Medium: Nutrient medium per U.S. EPA, 1978. This nutrient `medium provided all mineral nutrients essential for algal growth and also smeerdvieudmaswatshe8.d0i.luent for all algal operations. The pH of this synthetic algal wSatoscpkraepnadretedsitnsaollgualtimoendpiruemp,araantdioand:deAdpdriirmecatrlyy 1to00t0hemegx/pLossutorcekvseoslsuetliso.n _ Exposure vessels: 250 mL Erlenmeyer flasks containing 100 mL test Asgoliuttaitoinona:ndCconatpipneudouwsi.th inverted glass beakers. Number of replicates: 3. Initial cell loading: 1.0 x 10 cells/mL. Number of concentrations: five plus a blank control @GUT2ZSS Lighting: Continuous lightingat 44 Ein/sec/m? using cool-white fluorescent lamps. Water Chemistry: PH range (0 - 96 hours): 8.0 - 10.8 (control exposure) 8.2-8.3 (1000 mg/L exposure) Test temperature range (0 -- 96 hours: 21.9 -22.3C (incubator) RESOLTS 0000 Nominal concentrations: Blank control, 62.5, 125, 250, 500, and 1000 mg/L 96-Hr. Algal Growth Response values Nominal Cell-Count Avg. Specific | % Change from GEoxnpeo-s{umrge (cells/mL) Growth rate Control 45B10,2000000 | o0o.04l0 || [[21520s [|feoroo ||_oooomr ||2 __] 95| [f[ oe5 [ 0 0 || ooom 0 w | >to] Element values: 96-hour ECs = 143 (130 -- 156) mg/L 96-hour NOEC = 62.5 mg/L. Element values are based on nominal concentrations. Reversibility of Growth Inhibition: Not conducted. Remarks: Testing was conducted on the mixture as described in the Test Substance Remarks field. The values reported apply to that mixture and not ~~ _ the fluorochemical proportion alone. Conclusions The test substance exhibits a 96-hour E,Cso of 143 mg/L with a 95% confidence interval of 130 to 156 mg/L. The 96-hour No Observed Effect Concentration (NOEC) was 62.5 mg/L. Submitter: 3M Company, Environmental Laboratory, P.O. Box 33331, St. Paul, Minnesota, 55133 DATAQUALTY 001259 tReesltiianbgi.litHyo:weKvieirm,istchhe rsaanmkipnlge =pu2r.itTy hweasstnuodty pmreoeptersltyhcehacrriatcetriearifzoerdquaanlditythe study in the lacks analytical solution. confirmation of the amountof fluorochemical proportion REFERENCES 0000 `ITnhciosrtpeosrtawteads, cofonHdaumcptteodn,byNEHnvaitrtohSeysretqeumesstDoivfitsihoen,3RMesCooumrpcaenyAn,alSyt.stPsa,ul, MN, Lab Request number J1884-3, 1991. oR Last changed: 6/28/00 0000 001260 I on : gr : ps BEST COPY AVAILABLE ; WaTete of ree - p----" Be i SRhGEiooBnOLT EE ae, 1,ORL aaa a ; as Lol Rn ee St SE , SOO Sh AE { i Ae BET I erS a R RE . Bae % eo Eo e i B - lq" - 3 o BEST COPY AVAILABLE ET SRle TETSL in iEECcooOrmotTreEororTSmhirennueoenksvac1auStseTaeohceote,m"opoxGeT iaecnnai,ttyoetts 2or 4fToa2rbeTFSCso-se2a0eJtCioFseeniEitoneTnp1toEht5Seete,Looae1l0gaEa0,onLSEeknleenuseest2Tr0ues R CcoonmcmmreaL rB tatrieonsoelsitalTiYeoEsw Nr iTienr,tmTyhtdas aaeinlte is ire ee ieteesee,--i,F8See--ronennr TLiiGeI 1`vas SaUMdjusted Iton44lbhiol/eec/a? rwiith a phoptoosptereidod2of214vmeerts eCsomrrmclAilgeoteniLuers"eedkeTRien51Stn$he1E8tSeLstL13w0TaHmsHartfroomm a eaon Reint-haon unserceulbtuare2 etaheastnevtats gs a Lae e & a R a G 9 i = ik og l Be eds 0 oo o ER ER a E 3 an GE p ma eres aw-e E Lv Tmdea Bn le ac o al a iE Bl J fE e e E 4 E laE o a ean aed j ay 1 fbr AE RHA J " \ ny 001263 C T R TLTE rRaSRREEeeory RIAILABLE :g E02 aon 3 Summary 2 . 3 TT nen ot mien - . _ wo ---- Eg . ve wt eri . } 652 vn meterees in Lom A A FeEL E a EE ln i se Ge nd bia Bei aa E re Go. ol 4 5 Bl Ea | Gadeady nant a JE | Ee | a eo oh oa B - } . .g Lo BEST COPY AVAILABLE i se"anin ` LL ett ed TT mai 7. acon ae tom ote toe , lo ommemmesin * : et ptcecoin " | 5 Table A.1. Temperature seasured during toxicity test 1 Eo En B 08000 rien.on seiruces ductog sontetey tome 1 i og Fen S ShS edE UR sie a a HE SAR @etaes ede a Peae ee |j a iy SE i f EEcetith d SiLeEs | ES gas. i 0 { pn 3 Ed E PRT BEST. COPY AVAILABLE B cbtarcitiaTvheeitsoef"wahtsltohysswtu"unhdls "sEeretpwnov.oSSttnbreaysrrsc3oaexnCoicomvnremhrsnpestaoinnsoayn,bsi8tn.Seouvpsitee,taWotitnsa1PseoIetslT,ero2Tee. r oereedTons tii on: rosteoeenreeisemaeis5res cto"ehnheaen:e s3o SSpa Tpentts Cok pErensehnt S170 } } STnvimcoasFyel oamaisteoino(noe mvyiuck3ot,ohyi9t"9ea3s"h,s clSBhaoimopoeluiesogci Womtetbeeotraetd291e3a704)4W RwoaRrs ApdeL enleTiIveereTedeetto = g 32 SShhe GSish Nuc roo EtacerTatur,e. AA reservessale. (tpnpiiesniaesttatyy tro seam x Gbais | tmnorneitnTgaYtaethelnsyeBs"ae5met5e5tatornTWeEinsEuccEichtleieneotmfioaniR eoshfetni(eeoe sist.raBgmoueonta eiayeodhmfaoshceeE nma1etaotxceaiisceyh FDEaViEkRdBL ERED stwehelamtrAagritassd' Ghani uCSslaidneeaoorrnithneostteehstMpovweaneyshfrtShoemLam DcaLublrtnuraetTy toonriofFgiBneaelaeltyoafprtoMhRceeuterceiundbneifnnrenoedm mn iee dr e LI a VB WiRal EE eRen NLET ESAREeEeRE me SReey 2 B E REee sB00 mC 1, 100T mor Cua oionmsaan ElaEhLAAIUEfREfeoeSu0bc6oeb ntdS eiaasc vstatesmhes CBuoombrne. rdee omuefctsceu`rticsToelai2ocdo4/sptto,or. ECIUEA NR REgEeEaIrReGdS E L SURERn T a Ee Sale ElliREeiE 1 SS eacRl Soe E E cE E eRTE RERR hoe an | gL a ; ae : er Rl Ed ) Ny 001265 fe; ; TILL cShmlient BBcuEcsStEmTissCItiOoPn,Yof AL +VAepIrmLemAtaB, tLivEe seeteoot -- eed TERT EI . ii<s fms Organochlorine w/e 2 w ic A:hi icine nwoig oo * on } gid Hote: MD = not detected at or above the reporting limit. La 2 3 i: Se 1 a fBR Br t algee adin e 0ines Ln DL eR RE iE | 1 L wm Id r SRE a eer 1a cii28 E70MantelCiE o Srl SI2 RR i; possi wel Ey en 3 Ed ) CAA ~001264 : BEST COPY AVAILABLE : ETTThooeoonlLteesmthRTwoasstaa c2chkon},duLcotteIdIiEopnaatt eaefsLteeaFmregeeioteattebmnphaeereE asisttueraeh,scofe c3tnm2cs+oci2euCnoSwcnihsteohfcktfcieevoe : UE npn as otis aw wey gine oor tee pr A SA e Co N os a op AS MLL Lr . SDETy The imatneroToIfeJalSu cloinLtnaitnHnsoEate bSapsrsee)nseeadsaveamacdtnetieanrdneobnod | fort Sor he J ; Tawits ot On sonioty tot wash Incrpeaced by stantcs | ins Fo R LSSE%iEstRoE atRisnticala,oe teBcO3.h.ni|tqu,nes",iTehp(eSrretepmheana,m Se19c8U3tn)T.fa-slaThaeorcbnienofstmwitat yl cwaoredimoccevhaiiincT nrgvtnlaeaecvdhe,sragowiefng ] i hi Ti LS ahieneiadneidnebys th1e3.0 arSphoeruerseh. ealeuiatentiny mbtractiog phoepeJrEfAiospToarcSednt Tchhatnis. frtohmr cont0esn9i Chalsasus Averays specliis, proven recefrom' BJEFaloLppoI itnhcihaoRo0nn0.teeft"eThderpeaecrucg,ee.ntr schapngee fcoe iGmtroSueotnrithaisoeol aiy,fiasatinvwaiedeiidne ntggo.Stcahvatetpvuacelvvieceeb5ib0ceiahnaea'. . 8[B0s betatme i en T mma RE TT hadh ML eaida E SEE Rhee GVrE SE a 0ois c ai E eE gd) 5R E Ecl i oa n Sa ee ee ERE gEels:LS ngn Sea | ps Ei [= Sree ; RA ; fo nd] - PB - No Ee SE ae y . . [BEST COPY AVAILABLE B i BEBlSoloR giAcal TaEnd wEater EEquality TdatRs BE geesrsted by the acute . ; Pt, sBBre RpTTroeeyR'10, T1sa, 5c; tnt7e0rS ueTseenso . i stso8o,wnr8srpoeenss<mt0e 2c2tee07n3 da 5. Sih gain LLei ae gSaiEeiSs E a aa Si5s # ukhee ELE Lisy E fe a aRe Ena a I Fi ae wBiyne EE f !i ; BE ]i I Ee era Te er pToai EeC arTR Ra " - I 001268 SEER 5 wy B BEST COPY AVAILABLE Nominal Nusbes of Cells per NillLliter x 20 (hour) KN a we oa wm ww arf "as 1 10 20 " 52 220 ros p08 Sas 43 & 401 i. TENSE EC B ! "soo 32 10 12 . bierop= Mid 10 Lx io lena Sek) : s 9 sg 8 Ge Re eg, 8 Si PLE y ano: a ERE Ea R aEallRee o > ) rT he f 001265 T : ge E% *7 i; Ties] paces dake ree sted a sea section ute mm mmm mmm i er Te ane me ve ne sone Te oom ) Loe -- F000 : ; 3a otis oi oe on 0.000 -0.009 ~0.009 0.000 0 ian win io 100 >100 >100 >100 BEST COPY AVAILABLE FORE AEE He Li i La aE CooterBE a BE aa 14 as, if fires pilelee LO REISEDo foRLraia ng L Rsg T leee ao) ; In . R EERE 001270 " : Tuble 4. Nedian effective oncentraions'(RCE08)fromtoxletty tent -- TT i mee o-- hren-- od : awn HEE ems mmo # 24 hours. 22 sg 102 = 244 mrt Noving Average BI 72 ours 130 mg/L 12 - 10 41 mg/L - Noving Average ; RACE0 A, Ei Eo a BEST COPY AvaILABLE CU INF amin z} [RE co) Ee oa 8 | BE | L Snr bogiesaSt ER TE 5 (A id ] -- Agar EEE fama So Sa EL i T Ra ae hl : id J j ; # LE een : vi. armen aTi,p o0mr.eeevIdeEnS tor uninLofRTmca sucetinon 3tsokc a0 Se Cn. coer en fo sneiaion 8 450 rau, Slt Bloir -- : 3 BEST COPY AVAILABLE ET ER Laie VGogesa RE v rob a plod ge ;; h> r bas a 0 GE Ea ae EF 2 Ee JO 4T Sg a oa 5s EL E C Ta a N Es l TE]J t 8 Ey ie w - S---- 7001272 % Fr. ER CELE pe BEST copy AVAILABLE MataAun consi an hoseize sz Coie foo as HE iia gu Bil EREa RSE bL r aaB a eOR Sy Tbea ha ad e 54 SENG TG we GT a B fbrole iaaes ir a FE 48 4 ig See Foie p bound 3 . - A fe ---- a 001273] IRIE pe i . TAB Ak. Separate sedeured daring onto Sort To|t ewee sof mess es Day of Exposure Teaperature of Incubato*r,C ) N -_ ; Spt : BESTCOPY AVAILABLE ; SER Ek Ae Se A ba He HEE aaeege 3 Headl F ae ha e Sa a B bBess i4 fee B ba al al e TEE faz SE Pie nec PfE i j : ; _ E Ee o [Ea El EL B LP i : BEST COPY AVAILABLE Fle Ak 8 samen ain Sot on n _-- en we ees Se a } toro : ww wa 3 2 . 3 ol 03 = : i; os a J bbla ooam dlls ao os Ee SBeS 1 Erciasy BoFR lA hle A SRSO y CH By rE SE BEEFe I x Ce Bat 4 LEBi i PR a = ition SE Res = * Pa ) - = ee, i } i 00127!