Document j6RGjMgnbkn4N7eV3LZJw52k

Fe-129 : Jo Submitted to: - BIOSEARCH INC. pTeoe. lbeopx h8o55n8ep:hilade[lp2hi1a5. ]penns8yl4va8n-ia441991091 project Number = 77-1127 3 Company 3SMt. CePnatuelr, Minnesota 55101 Haterial: Sample Received: DateofReport: Test: Qbjecs of Tests Hethod of Test: 31 Company - T-2001CoC 11/21/77 Study Initiated: 11/22/77 Study Completed: 1/25/17 1/6/78 primary Skin Irritation Study = Rabbits eTToieldneetdetrhmetoi"nseutbhjetehceitndtemagactrteereainaodlf miaryritpartoidounc,e abraded skin wihf eanny, of albino rabbits. hnoeeemtedhteehsocsdrcioebrmeipdnlgoiyonefdSethcientiotrnheesu1lt5te0ss0t.i4wn1ags,=seiHvmaaizllaaurradtoiutoson oSNot.cta1en67cn,estP.anR2d7e0g1Au9rl,taitci2lo7enssS,,epAtFdeemdmiebnreairlst1rR9a7et3gi.iosntera,ndVol. 38, oInbicautrrserdyiwnaeg2reosuuctplpilptihpeeedd.stouvdeAyrgrtaoheuwpiedxeofpearrsieimaxe.natlabOlinneosample [S2ineI5O}Tihhes She stratum acTnoainrmcnaeeltusn'subbuftafcikcnsioetnwateslnytaebrdreaetdpheedtdoaetrpmeoanneettroate rBNaeSOdluocvewieabldlecdwtiaonsgr.aepmpaliThnieedisnkttiaoncta.onf abtAhraea0ud.ze5oedthmpleaarntdpcsohireadtsneiowinenrteact hTinSt tloalecewdoansovwterhreapsptaehmede strrnaeubagbtlieytd.aarroeGuansd atnhde atnrunikmspervious animals to hold the patches in place. TTnheeowrrsaapepiwnipgreerwiaoasdlsaornedmmaovdteehdeaaftttreerattheesdeevnaedrnetaoysf-twwteoherehotueerxnsa.mtiyned: Trad braze method of scoring was employed. 000187 34 Company - T-2001CoC, Primary Skin Irritation Study. Results: Conclusion: = See Table 1. Btahseedsuobnjectthemaatcecroimaplanywionulgd tnaobtle,be callabsisniofireadbbiastsawpirtihmianrytheirdrietfainntititoon oTfc) th(e4) Acatn-dRerfeeqrueinrcees: noSecctaiuotnion1a5r0y0.3 Tabeling with respect to that section. Karl L. Gabriel, V.M.D., Ph.D. Director 00188 TABLE 1 primary Skin Irritation Material: 3M Company - T-2001CoC, as supplied. Reading Erythema and Eschar Formation (Hours) Intact Skin 2 Intact skin 72 Abraded Skin 24 Abraded Skin 72 1 Rabbit 23 Number 456 Average 000000 000000 000000 000000 subtotal 0.00 0.00 000 000 0.00 gdema Formation Intact Skin Intact Skin Abraded Skin Abraded Skin - 2 000000 0.00 72 000000 0.00 2 000000 0.00 7 000000 0.00 subtotal 0.00 Total 0.00 primary Irritation Score: 0 600189