Document gre8LY6ZqojjZ3JJ255gRvLL

TO: Don Wharry, Dan Plummer *66: SWltS: RF XF: DS/Sfi b f//aJ -, Std FROM: DATE: Interoffice Communication SUBJ: Tom Grumbles August 5, 1985 TRACE COMPONENTS IN PRODUCTS VISTA As you are aware, the requests for specific data or statements regarding product constituents have increased. In many cases, this is a result of the OSHA hazard communication standard which requires any carcinogens present at greater than 0.1% and all hazardous materials greater than 1% (if the mixture has not been evaluated for hazard) to be listed on Material Safety Data Sheets. The recent Lubrizol request is a good example of this issue. To assist us in responding to these requests I have enclosed the OSHA carcinogen list. This is a compilation of the reference sources OSHA considers for carcinogen identification. Where reasonable, and with your help, I would prefer the responses for these requests came from this office. ) Thomas G. Grumbles ajo/007 Enclosure cc Carl Kerfoot I VVV 000001024 ' //r,d. - OSHA HAZARD COMMUNICATION STANDARD CARCINOGEN LIST Sources: 29 CFR 1910; NTP 1983 Report, IARC Monographs 2-Acetylaminofluorene Acrylonitrile Actinomycin D Adriamycin Af latoxins 2-Aminoanthraquinone 4--Aminobiphenyl l-Amino-2-methylanthraquinone Amitrole Analgesic mixtures containing phenacetin o-Anisidine and o-anisidine hydrochloride Aramite Arsenic and certain arsenic compounds Asbestos Auramine manufacture Auramine (technical grade) Azathioprine Benz(a)anthracene Benzene Benzidine Benzo(b)fluoranthene Benzo(a)pyrene Benzotrichloride Beryllium and certain beryllium compounds N,N-bis(2-chloroethyl)-2-naphthylamine (chlornaphazine) Bischloroethyl nitrosourea (BCNU) Bis(chloromethyl)ether (BCME) and technical grade chloromethyl methyl ether (CMME) 1,4-Butanediol dimethanesulphonate (Myleran) Cadmium and certain cadmium compounds Carbon tetrachloride Certain combined chemotherapy for lymphomas (including MOPP) Chlorambucil Chloroform bis-Chloromethyl ether Chlorophenols (occupational exposure to) Chromium and certain chrominum compounds Cisplatin Coke oven emissions Combined oral contraceptives Conjugated oestrogens p-Cresidine Cupferron Cycasin Cyclophosphamide ) Dacarbazine DDT 2,4-Diaminoanisole sulfate -1- 2,4-Diaminotoluene Dibenz(a,h)acridine Dibenz(aj)acridine Dibenz(a,h)anthracene 7H-Dibenzo(c,g)carbazole Dibenzo(a,h)pyrene 1.2- Dibromo-3-chloropropane (DBCP) 1.2- Dibromoethane (EDB) 3.3- Dichlorobenzidene 3,3'-Dichlorobenzidine 1,2-Dichloroethane (EDC) Dienoestrol Diepoxybutane Diethyl sulphate Di(2-ethylhexyl)phthalate Diethylstilbestrol (DES) 3,3'-Dimethoxybenzidine 4-Dimethylaminoazobenzene 3*3*-DimethyIbenzidine Dimethylcarbamoyl chloride Dimethyl sulfate 1.4- Dioxane Direct Black 38 Direct Blue 6 Direct Brown 95 (technical grade) Epichlorohydrin > Ethinyloestradiol Ethylene dibromide Ethylene oxide Ethylene thiourea Ethyleneimine Formaldehyde Hematite underground mining Hexachlorobenzene Hydrazine and hydrazine sulfate Hydrazobenzene Indeno(1,2,3-cd)pyrene Inorganic Arsenic Iron dextran complex Isopropyl alcohol manufacture (strong-acid process) Kepone (chlordecone) Lead acetate and lead phosphate Lindane and other hexachlorocyclohexane isomers Manufacture of magenta Melphalan Mestranol Methoxsalen with ultra-violet A therapy (PUVA) 4,4*-Methylenebis(2-chloroaniline) (MOCA) 4,4'-Methylenebis(n,n,-dimethyl)benzenamine Methyl chloromethyl ether Metronidazole J Michler's ketone Mirex Mustard gas VVv Qqoq *02 6 -2- 2-Naphthlamine alpha-Naphthylamine Nickel and certain nickel compounds Nickel refining Nitrilotriacetic acid 4- Nitrobiphenyl 5- Nitro-o-anisidine Nitrofen Nitrogen mustard N-Nitrosodi-n-butylamine N-Nitrosodiethanolamine N-Nitrosodiethylamine N-Nitrosodimethylamine p-Nitrosodiphenylamine N-Nitrosodi-n-propylamine N-Nitroso-n-ethylurea N--Nitroso-n--methylurea N-Nitrosomethylvinylamine N--Nitrosomorpholine N-Nitrosonornicotine N-Nitrosopiperidine N-Nitrosopyrrolidine N-Nitrososarcosine Norethisterone 0estradiol-17B Oestrone Oxymetholone Phenacetin Phenazopyridine and phenazopyridine hydrochloride Phenytoin and sodium salt of phenytoin Phenoxyacetic acid herbicides (occupational exposure Polybrominated biphenyls (PBBs) Polychlorinated biphenyls (PCBs) Procarbazine and procarbazine hydrochloride Progesterone B-Propiolactone beta-Propiolactone Propylthiouracil Reserpine Saccharin Safrole Selenium sulfide Sequential oral contraceptives Soots, tars, and mineral oils Streptozotocin Sulfallate 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Thioacetamide Thiourea Thorium dioxide o-Toluidine and o-toluidine hydrochloride Toxaphene Treosulphan to) yyy 00000^^ -3- 2,4,6-Trichlorophenol Tris(aziridinyl)-para-benzoquinone (Triaziquone) Tris(I-aziridinyl)phosphine sulfide Tris(2,3-dibromopropyl)phosphate Uracil mustard Urethane Vinyl chloride -4- WV 000001028