Document goabZXKG98jyBJKG6qN9Ov6Q

Nr. Nerls Hughes October 11, 1965 Past 2 surfaoee, vapors of the fluid and possible daeonpoaltlon produet* (depending on the temperature of tha haatad surfaee) may be irritating if inhaled to the degree that workman will not voluntarily expose themaelvee to taxis concentrations. No haxardoua exposure should result during the Interval required to shut down the system and obtain suitable respiratory protective devicea during repairs to the system. Ve would not anticipate any greater hasards during routine maintenance of a system containltg( Pydraul A-200 than would be present if the system contained a phosphate base fluid. It would appear to be good practloe to wipe dry any equipment before doing any welding on surfaces which might be "wetted" with or have a film of either type fluid on them. If the above Information does noti answer your specific questions pleas# let me know directly ^or through Nr./ Miohols. Very truly yours. n e k. . Klmef Ba wheeler Manager, invlronmental Health Nodical Department SPWimjb eei K. Oaston, Safety Supervisor, Chevrolet Dr. J. J, Srandl, Nedleal Division, Chevrolet J. NsMell, Plant tagineer, Chevrolet Prank DlSlacosw, Purchasing Dept., Chevrolet Neck Nichole - Monsanto, Cleveland CC - O.L. lio m -v \ C 1 l-O; ^ Wl t O / HONS 09117^ Ootober 11, 1965 Mr. Marl* Hugh** Chemistry Supervisor Chvrol*6 torg* riant Tonawanda, N*w York D*ar Mr. Hugh**i 04~ 1-K.y -- Maek Niohol* of our Cleveland office ha* asked m* to forward toxicity and *af* handling information for(Fydraul A-goo.g Animal toxicity atudiaa with thi* produot hav* indloat*d)that th* oral l*thal do** (U>sq) to rat* l* 10,500 milligram* pr kilogram. Th* lethaldo** wh*n th* material waa applied undiluted to th* unbroken *kin of rabbit* la approximately 1250 milligram* par kilogram. Wa oonolud* from tha abov* that aooldental ingaatlon on th* part of human* i* not a particular hasard in view of th* nigh oral lethal do** in rat*. Similarly, *lngl* massive akin axpoauras should not b* immediately haaardou*. Th* lethal do** obtained in skin penetration atudi** i* uoh, however, that prolonged and repeated akin eontaot hould b* avoided baeaus* of poeaibl* ayatmaio *ff*ot*. In addition, prolonged and r*p*at*d *kin eontaot may lead to *kln irritation. 1 ! < 1 ; w* al*o f*al that vapor inhalation ahould b* avoided whan \ th* fluid la heated to elevated temperature*. Suoh exposure t again relate* to prolonged or repeated exposure* rather - . - \ than *hort-t*r* ma**lv* or aoute *xpo*ur**.Jih th* oa*e of 4 V r thV~IAtt*r.Wor1B**n *uuld~not voluntarily txoo-- th*n**lv** to~~ione*ntrations that are haaardou* beoau** of irritation of 1 y ' th* respiratory traot. / Th* use of Pydraul A-800 in industrial hydraulle fluid appllcation* should not present toxicity hasard* during th* transfor of th* fluid from original container* to th* hydraulle yatma. Obviously when th* fluid 1* within th* hydraulle system, there ahould be no exposure and consequently, no hasard. In th* event of rupture of hydraulle line* and subsequent splashing or spraying of th* fluid on th* h*atd I MOMS 091173