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FBOM 1918 SO 1922.
la the spring of 1918 Harvard University received gifts* largely fro Hew England issirafaotiirers, In order to develop the subject of health la industry* Si subscribers to this fund understood that the Uaiveretty would employ the oeney for research md publicity mrk of each type a ses@fi desirable* sad fox* the training f industrial j&y&loiaas md other directly connected with health wotfc in industry* t&e work aceijlishd through this fund since 1918 is as follows*
A* ^SSSMSsJ^aMSSf*
1. Ludlow investigation.
2h# laboratory of .Applied Biysiology has collaborator with
th clinical section of tho division of industrial Hygiene* under
the directioa of Sr* Wade Wright* in the investigation of conditions
ia the Ludlow sill*' She Ludlow Associates are large producers of
jut products aai mm anxious to 4rt&is. whether working with
jut resulted la beans to the.tr es&loyeee* She jaaaofss tuning
processes subjected the workman to dust'vfcicrs* in. the sals consisted
f fin partiel of jute* but which als contaise^|y^rtaiu amount
of dirt accumulated when tbe juts was baled ia Xa&ia^ Sh^'Twu^i^
f this establishment reouired the work of Dr* c* ?:* ri|sj^D@aa| .
r'?M>y
, " ^ AV !r* H M* Thomson* who measured dust concentrations uslag such d^paratus
as was available at the time (1919h Dr. t?ade Wright* who.made
shysieal examinst ions on a number of tbe employees wfeonihad been \;
aoss mi throat condition of tIm.&mm group of ejaployessj and
Sr* (Joorg Kolw* of the igassiiolragetts Qeaorsl Hospital* who made
X~y photographs of th chest of the individuals soleoiod for study*
fh entire invest igatioa required ahui a month* tiw and
rtuit#d la establishing that prolonged work la Jut does rosu.lt la
certain ehroaic fibrous hangs la th lungs*. apparently not of very '
serious haraotor* fhe Ludlow Associates were advised a the basis
of thee -fladings* In order to he assured.? their position* to
Install hotter ventilation in certain parts of the sills, and m
y@cte the duet to * great m extent' as possible,
publication of the invest legation for the. Ludlow Associates .has
Men withheld until the fall of 1922, when a second survey of th
Mils will he sad following improvements which the Company has
ffeeted, and the finding of this Survey will h contrasted with
those ef the earlier ones to he iesnod*
.
2* Lead Investigation*
the desire of th Lead institute that the attack upoa this problem should follow whatever line the University belloved profitah 1 m& that the investigator should feel free to go over wojflc prev, tously done* In order to aooonpllsh this new task it became seoossary to remodel the laboratories to sow stent sad to appoint
additional personnel. ft investigation was placed to charge ef
Dr* 3* 0# 4b# and h tags msM Assistant Professor of Applied
Physiology. Dr, 4ub secured Dr. , T. Fairhall, Dr. J. 4*, K^t
Mrs. Marion' D .'Fraafcfwrter* Miss &mie.3 Htoal,-Miss Dorothea Smith,
-and Dr, 3* -W,.- S.''Brady as as is feats. Bib first necessity in the whole problem of lend poisoning
resides in absolutely accurate methods for-, lend detection. Dr.- fair- V
ball and Miss Minot'have spent the -past year la reviewing-and testing'
out published-methods -for. lead determination in animal tissues, and
Dr* Fairhall has.demised and.-has published m mthod far superior
to any-a* yet available, ft,is method, while useful for refined
laboratory worJe, is too. difficult for ordinary clinical .purposes*
sad Dr. F&lrfaall Is mm developing a shorter sad stapler method for us
la ordinary hospital, and industrial practice. Mss Minot ha bom making studies on the distribution of lent
to chronically poisoned aainais. sad has beoosa particularly interested
in the fact that lead is stored la the bosses - mt to-to#'marrow but
In the hard bone. Her results upon, the subject areextraordinarily
interesting and have baoos so positive that the laboratory is- now
iQMkt!ti j a :)u ]3M J^AVH^h
in a position to search for human autopsy arterial "to refer t^^|i..ea~
fira&tioa. Apparently lead is invariably to some
bones ad aay raaato there for long periods of tiae* ft subject
for inquiry to this investigation i naturally the mean's .by .which this
load &ay be liberated frea the bones .and so oause poisoning.
Dr. 3* '/ R- Brady has been studying the elimination of lead throng
.the bile and the .efforts of potassi iodide upon this eltedb&tioa.
His worh has not shown that potasslm iodide is f service is this-' -
orrlc is this particular
Dr* J A* ioy has hmn tsskta# oxteaoivo morphological studies
apes the bla-eils ia lead poisoning sad has gained valuable
'imoudedg upon the esosation sad value of stippi lag
5r. iub sad aim .Salth haw booa iatoreatob is the etse of
sao&la la lead poisoning, sad'hay discovered that th' lead ia is
o^paroatly capable of *o*y peculiar offsets upon the awbraaep of
the rod cells Sieir results are of importaaco aot only la
explaining anoxia in lead workers but ia disclosi&g the actual
physiology of the red blood-cells
ffeo single-publication to date a the lead ^ofls- les
bead Studies? 1 The Ssttmt.loa of Iginnte paomats of bead ia Biological Material 1 l* pairfesll* Jour* lad* Hyg, 1922, 1*
Projected publications covering' -experiffleats mw ia progress
are as follows*
Lead Studies* II* fh Isic Concentrations of'-fcead ia Body
nmmm* L. % Fairhall
Load. Studios* III* fh Clinical petectlon of 'ftad ia Chronic Lead Poisoning L* * Palrfcall*
Effects of load oa Bod Slood-Colls J. C Aub and * Salth
'v^ASi0fu --''ip Sxoretl^1^
4b, J. * S* irady, and sc.' p* -
Acute bead poisoning and the Probable Bsplaaetlca of stippling ia Bed Bleed-Cells. J. A Hoy*
fh distribution of Lead ia the poisoned Ani&al A* 8 Minot