Document gbgGgaaBdb60zMdKyDZQbm3OJ

3M Corporate Toxicology and Regulatory Services 3M Center, Building 0220-06-E-03 St. Paul, MN 55144-1000 651 733 1773 Fax Certified Mail pi *7 r - *r t p January 8, 2007 NO CBI Document Processing Center EPA East - Room 6428 Attn: Section 8(e) Office of Pollution Prevention and Toxics US EPA 1200 Pennsylvania Avenue NW Washington DC 20460-0401 RE: TSCA 8(E) SUBSTANTIAL RISK NOTICE ON: PFHS and PFOS; Supplemental to Sulfonate-based Fluorochemicals, Docket Nos. 8EHQ-1180-374; 8EHQ-0381-0394; 8EHQ0598-373 Dear Sir/Madam: In July o f 2006 3M notified the EPA that preliminary data had been received from a study suggesting an effect of perfluorooctanesulfonate (PFOS) and perfluorohexanesulfonate (PFHS) on body weight, food consumption, and serum cholesterol in 15% dietary fat fed E3 Leiden transgenic mice in vivo. The final report for this study is enclosed. If there are questions, or if additional information is needed, please contact me at (651-7371374). Sincerely, Deanna J. Luebker, MS, PhD 3M TSCA 8(e) Coordinator Enclosure CONTAINS NO CBI 89070000087 90 U 0 U 0 0 t'