Document gbNLrZXJvQb58pbR15krxadye

y-*7 ICO Hedloal DepertMknt - St. Louie October 16, 1967 rmuui. 290 -- acut* toxicitt testino J. 8. Davidson W. R. Rlchard/L. R. M. HcSsen C. 1. Ctrl? R. Okvis I, . ov J;.: ' ', ; ,- I ' ' i I Undiluted fydraul 230 mi classed as practically non-toxic when------adslnletered orally to Mind sex rats. Tbs acute oral Ltfcg ms 10,900 at/kg. N>st deaths ooourred in two to throe days. "Toxlo aigna were loss or appetite and increasing weakness. the undiluted oenpound was eleased as Mildly toxlo when applied to the clipped intact akin of Mixed sex rabbits, the acute Minimi lethal dose was creator than 1260 but less than 2000 mg/kg. Tim to death was 5 to 7 days. Toxlo signs were lethargy and weakness and within 2 to 3 days tresnrs developed. The undiluted oonpound was classed as a slight irritant to the clipped Intact akin or Mixed sex rabbits, following rcaoval of the ocapound after 24 hours contact with the akin, the skin was neansal within 4 days. The undiluted oenpound was classed as a Mild aye Irritant to the rabbit, mere was asm irritation luuedlately after application as evidenced by blinking. WstImimi irritation (alld) ooourred within the first hour of contact, following ncuoval of the oonpound after 24 hours of contact the eye was norual within 7 days. All rats survived a 6-hour exposure to the saturated vapors of the oonpound at anblent tiapomturc. The only toxic sign observed was aild lethargy. Zt is adviaed that repeated or prolonged akin contact be avoided. Mnove with soap and water. Xn case of accidental eye contact flush out with water. If Irritation persists consult a physician. . for eenparatlve purposes, Z an tabulating the results or this studyrffdraul 230 with those of Pydraul 312 and 135. The table is attached. Ml lien H. aunt, fit. D. MOtfaah Mloeursi Copy or report to Hr. Davidson ' MOWS 098025