Document gbJML1D9pEKd51nNmRXR1N8a9
**
Hr. 6. B. Bellly Director of Safety Bational Tub* Division
IDILDIIC
Kenneth N. Nkm, Dirac cor Industrial Bygiene
Toxic
As per your request, nay X sum*sc you consider Ineluding tbs following information with your transmission - of tbs onclossd tables of Threshold Limit Values for 1950."
The enclosed list of 'Threshold Limits" are loaoim under a variety of names, such as "maximal allowable con centrations," "toxic limits," ate. They are not exact delinea tions between baxard and non-haxard conditions, slnee they are derived from a variety of sources. Some are based upon studies with human subjects, others upon opinions derived by interpo lating from animal experimental data, while still others are based merely upon unsupported opinions from industrial medical and hygiene authorities. Bowevcr, the fact remains that these limits are often incorporated into state codes or used by state inspectors as exaet numbers above which a condition is dangerous. Therefore, in actual practice, it is important to maintain air concentrations of these gases, vapors, dusts or mists within such levels where possible or protect workers by approved respiratory devices.
Thase data are the maximum degree of air contamination to which one should be exposed upon a continuous t-hour daily and 40-hour weekly basis. Thr data, therefore, are degrees of air contamination which will prevent the development of chronic poisoning arising from continuous day to day exposures. Xt is our opinion that short-term exposures also should be maintained within such limits where practicable, because of the absence of good data on safe concentrations for preventing aeuts (sudden) poisoning. This approach is considered to be the best course of action because the human body does not respond in a dirset arithmetic relationship with the amount of contaminant in the air. Xn other words, it would not be prudent to expose an individual for one hour to eight tines the values shown in the enclosed table without respiratory protection, furthermore, state inspectors would no doubt consider such exposures as* hatardous to health.
mf USEI000106
Threshold limit Values for 1958
Adopted at Ike 20tk Annual Meeting of ike American Conference of Governmental Industrial Hygienists Atlantic City, April 19-22, 193d
Mtpriued fnm tit A. M. A. Arckua *1 Iniuurial Httlik ' Aufutt ItSI, VtL It, 0p. ITt-lt2
Cepfrifki ItSt, h Ameriem MtAietl Auodmia*
USEI000107
i
Threshold Limit Values for 1958
Adopted at the 20th Annual Meeting of the American Conference of Governmental Industrial Hygienists Atlantic City, April 19-22, 195&
Threshold limits should be used at guides in the control of health hazards and should not be regarded as fine lines between safe and dangerous concentra tions. They represent conditions under which it is believed that nearly all workers may be repeatedly exposed, day after day, without adverse effect. The values listed refer to time-weighted average concentrations for a normal work day. The amount by which these figures may be exceeded for short periods without injury to health depends upon a number of factors, such as the nature of the contami nant, whether very high concentrations even for short periods produce acute poisoning, whether the effects are cumulative, the frequency with which high concentrations occur, and the duration of such periods. All must be taken into consideration in arriving at a decision as to whether a hazardous situation exists. Special consideration should be given to the application of these values in the evaluation of the health hazards which may be associated with exposure to com binations of two or more substances.
Threshold limits are based on the best available information from industrial experience, from experimental studies, and, when possible, from a combination of the two. These values are based on various criteria of toxic effects or on marked discomfort; thus, they should not be used as a common denominator of toxicity, nor should they be considered as the sole criterion in proving or im proving diagnosis of suspected occupational disease.
These limits are intended for use in the field of industrial hygiene and should be employed by persons trained in this field. They are not intended for use. or for modification for use. in the evaluation or control of community air pollu tion or air-pollution nuisances.
These values are reviewed annually by the Committee on Threshold Limi's for changes, revisions, or additions as further information becomes available. The Committee welcomes-the suggestion of substances to be added to the list and alto comments, references, or reports of experience with these materials.
Submitted for publication May 5, 1958.
RECOMMENDED VALUES * Oates and Vapors
SVSSTAHCZ
PPM*
Acetaldehyde .......... ....... 200
Acetic acid ...........
Acetic anhydride ...
S
Acetone ................. .... 1.000
AcroWa ..................
Acrylonitrile ...........
Aflyt alcohol ......... AH)-1 ehloridr.........
S
s
Approx. Mr per Cu-M.t
360
25
20 2.400
\2
45 12 15
SvasTAMcc
PPM*
Ally! prop}-) disulfide Ammonia ................... Amyl acetate ............. .. Amyl alcohol
(iaoarayl alcohol) .. .. Aniline ....................... Anine ......................... Bmzene (baruon ....
2
200
100 5
Approx Mff per Cu. M.t
12 70 1,050
360 19 02 to
A t t
t usEioooioa
i
THRESHOLD LIMIT VALUES TOR J9M
StlMTAXCt
PPM*
Beruyl chloride ..........
1
Bromine .......................
1
Butadiene
(13-butadiene) ......... . 1,000
Butanone
(methyl ethyl lcetone) . 230
Butyl aeeute
(n-bntyl aeeute) ... . 200
Butyl alcohol
(butanol) .............. . 100
Butyiamine .................
5
Butyl celloioivc
(2-butoxyethanol) ... 30
Carbon dioxide............ 5400
Carbon disulfide ......... 20
Carbon monoxide ....... . 100
Carbon tetrachloride ... . 23
CtUotoivc
(2-ethoxytthanol) ... . 200
Callotolve acetate
(2-cthoxyrthyl acetate) 100 .
Chlorine .......................
1
Chlorine trifluoride ___
0.1
Chlorobctucne
(monochlorobenxene) . 73
Chloroform
(triehloramethane) .... too
l-Chlors-l-mttopropane , 20
Chtoropicrin .................
1
Chloroprtne
(2*chloro-13-butadicnc) 23
Cnaol (all itomert) ... 3
Cyclohexane ................. . 400
Cyclohexanol ................. . 100
Cyclohexanone .............. . 100
Cyclohexene ................. 400
Cyclopropane ................. 400
Dacaborane ................... 0.05
Diacetone alcohol
-
(Miydroxyd-methyl-
2-pemanone) .............. 30
Diborane ....................... 01
e-Dichlorobeniene ......... so
Dkhlorodifluoromcthane 1,000
1,1'Dichloroethane ......... 100
12-DichIoroxthane
(ethylme diehloride) .. 100
12-Dichloroxthylcne .... 200
Dichloroethyl ether....... 15
Dichloremooofluoro*
methane ..................... 1,000
l.l-Diehloto-l-mtro-
ethane ......................... 10 Dichlerotetrafluoroethanc 1,000
Diethylamine .................. 23
Difluoredibromomethane 100
Diisobutyl ketone ......... 30
Cu U t 3 7
2200
740
930
300 . 15
240 9,000
to no 160
740
540 3 0.4
330
490 100
7
90 22 1.400 410 400 1350 690 03
240 01
300 4.930
400
400 790 90
4200
60 7,000
73 160 290
i
SmstAitc* Dimcthylaniline
PPM*
Approx. Me per Cu.M.*
(K^hnethylenilinc) . Dfcncthylsulfau ...........
5 1
25 3
Diexant (dtcthylaDt
dioxide) ................... . 100 Ethyl acetate .............. . 400
360 1.400
Ethyl acrylate .............. 23
100
Ethyl alcohol (ethanol) 1.000
1,900
Ethylanrine................... 23 Ethylbenatne ................ . 200
45 870
Ethyl bromide ............ . 209
(90
Ethyl chloride ........... 1.000 . 2.600
Ethyl ether .................. . 400
1200
Ethyl formate ............. . 100
300
Ethyl silicate .............. . 100
(50
Ethylene chlorohydrm .
3
16
Ethylenediamine ........... 10
30
Ethylene dibromide
(12-dibrumocthanc) . . 2$
190
Ethylene imine ............
3
9
Ethylene oxide ........... so
90
Fluorine .......................
0.1
02
Fluorotrichloromcthane .. 1,000
5,600
Formaldehyde .............. . 3
6
Furfural ........................ 5
20
Gasoline ........................ . 300
2,000
Heptane (heptane) .... 500
2.000
Hexane (hexane) .. . 500
1,800
Hexanone (methyl butyl
ketone) ..................... .. 100
410
Hexone 'methyl itobutyl
ketone) ...................... 100
410
Hydraxine- ..................... 1
1.3
Hydrogen bromide......... Hydrogen chloride.........
5 5
17 7
Hydrogen cyanide ......... 10 Hydrogen fluoride ......... 3
11 2
Hydrogen peroxide, 9091
1
1.4
Hydrogm sdenide ......... 0.05
02
Hydrogen sulfide ......... 20
30
Iodine ............................ 0.1
1
tiophorone .................
25
Isopropylamine .............. 5
140 12
Mesityl oxide ................ 25
100
Methyl aeeute ........... 200
610
Methyl acetylene ........... 1,000
1.630
Methyl acrylate ............. 10
33
Methyl aleoho!
(methanol) ................ 200
260
Methyl henoidt ............. 20
(0
Methyl ctllotelve
(2-methoxyxthxnol) .. 23
00
Methyl callotolve aeeute
(ethylene (lyeol mono-
methyl ether acetate) .. 25-
120
Methyl chloride ............. 100
210
1
USE1000109
AM. A. ARCHIVES OF INDUSTRIAL HEALTH
lAftrAHCK
PPM*
Methyl*! <4mmhoxy-
methane) .................. IM
Methyl chloroform
(1,1.1-crichloroeihane ) 500
Mcthykydohexane .... . 500
Methylcydohexanol .... . 100
Methyleyclehexanone .. . 100
Methyl formate........... .
Methyl iaobatyl carbinol
(methyl amyl alcohol) 25
Methylene chloride
(dichlofanixthanc) ___. 500
Naphtha (coal tar) ..... 200
Naphtha (petioleum) ... 500
Nickel carbonyl ............. OlOOI
Nitric add...................... 10
f-Kitroaniline ................
1'
Nitrobemene .................. 1
Nitroethane .................... 100
Nitrogen dioxide........... 5
Nitroglycerin.................. 05
Nitromethane ................ 100
2-Nitropropanc ___
50
Nitrotoiucnc .................. 5
Octane ........................... 500
Otone ............................. 01
Pentane........................... 12)00
Pcritanone
(methyl propyl ketone) 200
PercMomhyienc
(tetrachloroethylene) . 200
Phenol ........................... 5
Phenylhydradne ............. 5
Phosgene
(carbonyl chloride) .. 1
Approx. Me. per Ca.M.t
3.100
2200 2.000
470 460 250
10C
1250
too
2400 0007
25 6 -5
310 9 5
250 130 30 2450
02 2.950
700
1450 19 22
4
SuaiTAHcc
PPM*
Fhoepliirte ....................
Phephonte trichloride .
OS
Propyl aerate ............. . 200
Approx. Me per Cu. M t
0.0?
3
340
Propyl alcohol (ieopropyl alcohol) . . 400
900
Propyl ether
(ieopropyl ether) ... . 500
2,100
Propylene dichloride
(12-dichloropropane)
75
350
Propylanc mine ....... 25
60
Pyridine ....................... 10
30
Qdnone .......................
0.1 0.4
Stibine .........................
0.1
0.5
Stoddard solvent ....... . 500
2.900
Stymie monomer
(pbenytethyknr) .... . 100
420
Sulfur dioxide .............
5
13
Sulfur hexafluoride ... . 1,000
600
Sulfur monochloride ...
1
6
Sulfur pentafluoride ...
0025
045
p-Tcrtiarytmyltolucne . 10
60
1,122-TctrachIoTuethane
5
35
Tctrihydrofaran ......... , . 200
590
Tetranitromcthanc ......... 1
8
Toluene (toluol) .......... 200
750
o-Toiuidine ...................
5
22
Trichioroethylme ........... 200
1.050
TriAuoromonobromo*
methane ..................... 1,000
6,100
Turpentine ..................... 100
560
Vinyl chloride
(chloreethylate)......... 500
1400
Xylene (xylol) ............. 200
870
hn> #f ar r u far milieu pmt f if ty fhww.
t Awnum MiUiruu ter atfctc atttt < nr.
Twrfe Xtott* Fmes, and Mixti
Mr per
SvtsTAMCt
Ca M4
Aldrin (144.4.10,10-hxxachloro-
l,4,44444ahexahydrol,4,5,8-
dimethanenaphthalcnc) .................... 045
Animate (ammonium nlfamatc) .... IS
Antimony ............................................. OS
ANTU (alpha-oaphthyi-thiourea) ... OJ
Amnic ................................................. 0.5
Saritm (eoiaMe cemposnds) ............. OS
'Cadmhm oxide ftane ........................ 0.1
Cakrtxs inanste ................................. 0.1
CMunfant (U44A7A8-
octaehloro-3e,422e-tetrhydro-
42-raethanoindane) ........... ......... 2
Chlorineted camphcne, <0%................. 05
Chlorinated diphenyl oxide ................ 0.5
Chierediphenyl (42% chlorine)......... 1
CWocodiphenyl ($4% chlorine)......... 0.5
Chromic add end chromate* (as CrO) 0-1
Mg. per
Sumtaxm
Cu. M.t
Crec herbicide (tedium 2-12.4-
dichlorophawxy] ethanol hydrogen
tulfate) ..........................................IS
Cyanide (a* CN) .............................. 5
2,4-D(2.4-diehlorophenoxyacetic add) 10
DDT (24-bit[p-ch)oropheny))-l,l.l-
trichioroethant) .............................. 1
Diddrin (144.4,10,10-hexaehloro-
62-epoxy-l,4,4a4.62.8.8s-octahydro-
1,44,3-dimethMio-naphthalene) ....... 025
Dinitrebotrene ................................... 1
Dinitrotoinene ..................................... 1.5
Dinitro-o-creeol ................................. 02
EPN (O-ethyi O-p-nitrophcnyl
thienobcnaencphocphonate) ............ 0J
Fcrbam (ferric dimethyl
w
in Vtl. Jt. Amo.. BX
THRESHOLD LittlT VALVES SOU Iff!
Svmtamck
PPM * Mi. nr
Cu-M.t Farrevanadium dull ........................... 1
Fluoride .............................................. U
Hydroquinone ..................................... 2
Iren oxide ftxne ................................ IS
Lead .................................................... 02
Lead aracnite ...................................... 015 Linduie (hexichloroeyclobtixne,
mm* isomer) .............................. OS
Msfnciiixn oxide fame....................... 15 Matathion (O.O-dimeihyl dithiophot-
prittc of diethyl mcrcapcotuccmate) 15
Mantwcre ........................................... Mercury .............................................. Mercury (orfanie compound<) ......... Methoxychlor (22*ii-y-methoxy.
6 Ol 001
phcnyM.l.l-trichlorocthane) ......... 15 Molybdenum
(reluMe compound!) ....................... 5
(inioluble compound!) .................... 15
Nicotine .............................................. 0.5
Panthion (O.O-diethyl O-p-
nitrophatyl thiophoephate) ............. 0.1
Pcmachlorenaphthalcnr ..................... 0.5
PeniacMorephenol .............................. 0.5
Pbotphorua (yellow) ......................... 0.1
Photphorui penuehloride .................. 1
Phosphorus pentuuUide..................... 1
Picric arid ......................................... 01
Pyrethrum ........................................... 2
Rotenonc.............................................. 5
Selenium compound! (u Se)............. 01
Sodiian fluorencetatc (10M) ............. 01
Sodium hydroxide .............................. 2
SUMTAHCT
PPM * Mr per
Cu. m. : Strychnine .......................................... 0.15
Sulfuric acid ..................................... 1
TEDP detraethyl
dithicnopyrephofphate) .................. 02
TEPP (tetraethyl pyrephoiphate) .. 0.05
Tellurium ............................................ 01
Tctryl (2.4.6>trintropl)cnyl>
meUiyfatitramine) ............................ 1.5
Thiram (tetnmcthyl thiuram
dimlAde) ......................................... 5
Thallium (aolubic compound!) ....... O.i
Thanhan dioxide ................................ 15
Trkhlorenaphthalene ......................... 5
Trinitrotoluene ................................... 1.5
Uranium
(ioluMe compound!) ................... 0.05
(insoluble compounds) .................... 025
Vanadium
(YiOtduit) ..................................... 0.5
(V.O fume) ................................. 0.1
Warfarin (5-|e acetonylbentyl]>4>
hydrexycoumarin) ........................... 0.5
Zinc oxide fumes................................ 15
Zirconitan compound! (ai Zr) ......... 5
PaeMammy: Per wrwi--iSh --niitiinw tl radm.
iSMSfMI hi Mt, SM **11ITTHI PtmiMlbk AMUftU Oi
m tfct H--in SWy tM Mtxiaram Ptrmis.
tM Cwinintii m Atf aM Wtur," HsndMt 52.
V. S. Dianwn pi r--nifti. Nati-->1 Burtiu (
liiwdirrfi. Mirck. 1955. la tdiitmu tst 'P'rrtmmWs
Dm* itpm txwrnpi Iwrm pi
JUdistisn/' Hsnd-
fcak 59. U. $. Dawn if C--ams. NsiisasJ Imiu
pi Sttafcr*. UpL 24. 1954.
Bfmtoa pi tfct t*a paMmtwni wadaavd aW* is in
Wtrtu.
S Minify-- pi 9mm. ham. r ansi ptr cate amtr sf sir.
Mineral Duata
Suistaxci
MPPCPI SwaPtAxet
MPPCF |
Aluminum oxide ............................... 50
Silica
y'Aibeitoi ........................................
5 hifh (above 50*5 free SiO.) ... 5
Dust (nuiianet, no free lilicm) -- 50
medium (5 to 50% free SiO.) .. 20
Mica (below 5* free tilka)......... 20 Portland cement ............................... 50 Tale .................................................... 20
low (below 5% free SiO.) .... Silicon carbide .............................. Soapstone (below 5% free SiO.) ..
I Millim. *1 nnda ftt mSk Imt / tir
50 50 20
SuartAxa
(x) Acetylene tetrabeomide .............
(x) Allyl ftyodyl ether (AGE) .............
(x) Beryllium ............... (x) Boren trifluoride .. (x) -Butyl ilyddyt
ether (BGE) ..
TENTATIVE VALUES
Approx. Mr per Cu.M.1
14
45 27/01* 3
270
StUSTANCt
ppmh
(x) Butyl mercaptan .. Chlorine dioxide ..
(x) Gtloreacctaldehyde (x) Chlorebrecnomethane
(QBrCH.) .... (x) Diflycidyl ether
(DGE) .............
10 0.1 1
400
10
Approx. Mb. per Cu. M.5
35 0.3 3
LlOO,
55
181
USEI000111
AHA. ARCHIVES OF INDUSTRIAL HEALTH
StntTAHa
PPM I
(x) Dimethyl formamid* 1,1-Oinitthjrl hydrwin* ....... .
(*) Dipcopyhntglycobacthytothar
(x) Ethyl marcapcaa .. (x) Forlwyl alcohol .. (x) Glyddol ................
tec-Hexyl acetate
(x) laoproppl glyddyl ether (ICE) ...
(x)Uthiixn hydride .. (x) Methyl mercaptan (x) Methyl styrene .. (x) Monomethyl aniline (x) Pandichtoro-
benient ............. <x) Perchloromethyl
mercaptan ......... (x) Phenyl (lyeidyl ether
(POE) .............
20
OJ
too 2S0
SO SO too
so
so 100
2
75
at
so
Approx. Mg per Co. M.T
0
I
too
*40 200 ISO $90
240 2Sr/m* 100 400 9
4S0
as
310
Sdmtaxcx
PPM II
MriWuap>O|>|Pu|nnCta KulmJ -Propyl nitrate .. (x)Prapyime oxide .. (x) Tertiary butyl
ttotol ...............
(x) Totytaoe-2.4. diiaoeyanate ....
13-Trichloropropane..
(x) Triethyl amine .... Triorthoerayt
2S too
100
ai
so
25
(x) Vinyl toluene .... 100
(x) Yttrium and inorganic compound*
(x) XyBdiae ................ 5
(x) Total decompoiition pradueu.............
(x) Pantaborane (BaHa)
Approx. Mg. per Cu. M.tf
1 110 240
300
0.7 303 103
0.1 460
S 25
I Pam tt no ar (It far mlbaa fun a< air *r aalwaa.
I AaumuRua aulluraaaa far <*t aaatar W jur.
(x)Tkaa* *Utm uhmW an tka aanaanaa lot (u Its?.
L'rm! i
4au art fartkca<nif. h * manual tku ataaaaaWm i
, af lima uaaariala ta atfeiak warLm
William L. Ball W. Clam Coortx
H. . Snxtxcxx Kuril H. Jacoosoh
Havtv B. Euan* W. H. Ruxmn Allah L. Comma*. Ckatrmn
1(2
USEI000112
n. `.`UK