Document gb9a07k5En153zZnw1Er7x7aa

Internal Correspondence * I BACK TO MAIN Conmclrcial Chemicals Analytf cal Report 6245 TO: M. T . Pike - 236-2A From: L. 0. Wfnter - 236-28 subject: CS-2070/CS-2151 P a r t i t i o n Coefficieiqs Dale: A u g u s t 3, 1981 Reference: Comnercial Chemical Analyttcal Request #I6565 1 ) The method reference i s Chiba, Twnoda, Haraguchiad Fuwa ."Determination o f Fluorine i n Wine and Blood Serum by A1uminum Monofl uoride Molecular Absorption Spectrometry a n d nf t h a F1 uorlde Ion Sel ectlvc! E l ectrodt!" Analytical Chmist r y , 1980, Vol me 52, pages 1582-1 58!i. 2 ) Environmental laboratory protocol f o r the d e t e n l n a t i o n o f the d i s t r i b u t i o n c o e f f i c i e n t of s o l i d arid l i q u i d substances f n n-octanol/water. Introduction: A l l g h t yellow l i q u i d labeled CS-2151 and a l i g h t yellow s o l i d labeled CS-2070 were received from V. Pothapragada November 18, 1980. The CS-2070 was reported t o be the dried s o l i d from CS.~2151which I s 25% s c l l d s in water. The samples were sutmltted f o r PM. c h a r a c t e r i z a t i o n . The CS-2070/2151 was p a r t i t i o n e d between water and n-octanol t o determine the distribution, -E x p e r l m e n t a 1 : CS-2151 uas d l l u t e d w i t h water t o give a concentration o f CS-2070 o f 10yg/ml o f d l s t i l l e d water. Equal a l i q u o t s o f t h i s sample and prc-mter s a t u r a t e d n-octanol (99+% Aldrich) were shaken slowly f o r 8 hours, t h e n allowed t o stand f o r 24 hours. The phases were separated and analyzed f o r t o t a l orgairic f l u o r i n e by atomic absorption (1 ). Standard was made u s i n g CS-2070 i n water and in n-octanol t o match m a t r l x and rccoverles, CS-2070 i s so'lublc i n n-octanol. BACK TO MAIN M. T. Pike Comnercial Chemicals Analytical Report 11245 August 3 , 1981 Page 2 II Results Distribution Coefffcfent (D) = - C_ oc n_ centratfon fii n-octanol . Concentration fii Uater - cc: J. 0. LaZerte, R . J. Seffl. R. A . Prokop 236 - D. R. Pauly 236-28 - W. H. Ptarlson 223-6SE - Y. Pothapragada 236-3A - E. D. A. A. Rciner Rfcker - 21-02 53-4N