Document gakNobwBr3ZZeK9y9yBz3LrNq
Benzene Health Reseach Consortium Budget as of April 20, 2005
A BC
D
E FG H
1
2 BHRC Overall Program Budget Approved April 12, 2005
3 (draft)
4
5
Approved
Approved
Requested
16 Dec 04 OC Increase 12 APR 05 OC
6
Item
mtg APRIL 05 mtg
7 UCHSC DP & ME Studies
$14,508,000 $3,824,769
$18,332,769
8 Irons (field expenses)
$1,413,428
$0 $1,413,428
9 AHSciences Case-Control Study
$2,283,095
$647,746
$2,930,841
10 Fudan University
$230,000
$76,062
$306,062
11
Total Research Costs
$18,434,523 $4,548,577
$22,983,100
12 Scientific Review Panel
$300,000
$0 $300,000
13 Ethics Review Panel
$64,000
$0 $64,000
14 External Pathology & Cytogenetics Workgroups(Cost in UC cost)
$0 $0
$0
15
Total Panel Costs
$364,000
$364,000
16 API Seed Monies
$0 $0
$0
17 Outside Counsel
$100,000
$40,000
$140,000
18 Public Affairs
$300,000
$0 $300,000
19 QAJQC Activities
$50,000
$0 $50,000
20 UCHSC Interest
$0 $0
$0
21 contingency
$590,272
$260,000
$850,272
22
Miscellaneous Costs
$1,040,272
$300,000
$1,340,272
23
Subtotal
$19,838,795 $4,848,577
$24,687,372
24
API Admin.'
$1,245,205
$200,000
$1,445,205
25 GRAND TOTAL
$21,084,000 $5,048,577
$26,132,577
26
27 * API administrative costs for one extra year (2007)
28
Page 1 of 15
4/20105
SHELL-MCCLURG-066010
Benzene Health Research Consortium Program Budget as of April 20, 2005
A 1 2 3 4 5 6 7 Cost Centers 8 9 Income 10 interest thru 12/31104 11 TOTAL INCOME 12 13 Cost Centers 14 UCHSC 15 Irons-Field Expense 16 Applied Health Sciences 17 Fudan University 18 Scientific & Ethics Panels 19 Communications 20 Outside Legal Counsel 21 QA/QC Support 22 API Administrative 23 Contingency** 24 25 Total Expenses 26 27 Fund Balance'" 28 29 totals may be off due to rounding 30 31 *ConocoPhillips paid full amend #2 in 2005: BP pay full remaining commitment in 2005 32 **not zero out because a mix of actual and estimated expenses match proposed budget difference due to a mix of actual vs projected expenses 33 *** Fund balance as of 12/31104 reflects program interest to date. Interest for years 2005-2007 is not reflected due to changing rates.
B C DE
BHRC Proje
Project #
Cumulative Actuals Inception Thru 4Q04
Proposed 2005'
16,715,000 50,692
16,765,692
4,395,097
X8105 X8106 X8107 X8108 X8109 X8103 X8104 X8110 X8100
10,137,850 788,486
1,391,014 124,090 166,772 294,161 64,529 0 871,150 104,473
13,942,525
2,823,167
3,367,208 262,000 534,843 80,563 79,250 1,946 30,031 16,667 184,995 159,933
4,717,436
2,500,828
Page 2 of 15
4/20105
SHELL-MCCLURG-066011
FG
H
I
1
""2 ted Expenses and Income Requirements
3 (draft)
4
5
Prior
12 APR 05
6 Proposed Proposed Program
Program
7 2006
2007 Budget
Budget
8
9 3,500,000 1,522,480 21,084,000
26,132,577
10
11
12
13
14 3,812,002 1,015,709 14,508,000 18,332,769
15 262,000
104,714
1,413,428
1,413,428
16 548,231
456,475
2,283,095
2,930,841
17 55,490
45,918
230,000
$306,061
18 74,250
47,396
364,000
364,000
19
1,946
1,946
300,000
300,000
20 30,031
30,032
100,000
140,000
21 16,667 16,667
50,000
50,000
22
184,995
200,000
1,245,205
1,445,205
23 222,933 362,933
590,272
$850,272
24
25 5,208,545 2,281,790 21,084,000 26,132,576
26
27 792,283
32,973 **
28
29
30
31
32
33
Benzene Health Research Consortium Program Budget as of April 20, 2005
Page 3 of 15
4/20105
SHELL-MCCLURG-066012
Benzene Health Consortium Budget as of April 20, 2005
1 2 3 4
Member
2-
~
A
BC
D
Consortium Agreement Amendment #3 Schedule A
(draft)
Original Budget Amendment No.2 Amendment No.3
$16,500,000
Revised Budget $21,084,000
Additional Member Contributions1
7
""""8
9 BP 10 ChevronTexaco 11 ConocoPhillips 12 ExxonMobil 13 Shell 14 Marathon3 15
16 GRAND TOTAL' 17 18 19 20 1 BP's increased contribution reflects $1,644,000 for amendment no. 2 plus $924,430 21 for amendment no. 3.
22 2 The share distribution has reverted back to the allocation specified in original agreement
23 3 Marathon was invoiced for its contribution, and is not a signatory of this agreement. 24 Marathon's earlier payment of $15,000 was not reflected in previous calculations.
25 ' Totals reflect rounding
$4,500,000 3,000,000 1,500,000 4,500,000 3,000,000 15,000
$16,515,000
$4,500,000 4,096,000 2,048,000 6,144,000 4,096,000 200,000
$21,084,000
$2,568,430 616,287 308,143 924,430 616,287 0
$5,033,577
EF
Program Total
Revised Budget $26,135,577
Maximum Financial Contribution per Member
Amount Paid as of 12/31104'
$7,068,430 4,712,287 2,356,143 7,068,430 4,712,287 215,000
$4,500,000 3,000,000 1,500,000 4,500,000 3,000,000 215,000
$26,132,577
$16,715,000
Page 4 of 15
4/20105
SHELL-MCCLURG-066013
G 1 2 3 4
5
H
6
Remaining Original #
Amount to be of Shares
Paid
7
8
9
$2,568,430
3
10
1,712,287
2
11
856,143
1
12
2,568,430
3
13
1,712,287
2
14 0 --
15
16
9,417,577
11
17
18
19
20
21
22
23
24
25
Benzene Health Consortium Budget as of April 20, 2005
Page 5 of 15
4/20105
SHELL-MCCLURG-066014
Benzene Health Research Consortium Budget as of April 20, 2005
A
BC
DE
FG
1 Sponsor Shares and Payment Schedule
2 (draft)
3
4 Approved Increase by Share & Co.
5
Approved Increase
$5,048,577
less BP amend #2 amt
6
& MAP $15K*
($1,659,000)
amend 3 share
7
calculation total
$3,389,577
Amena :.!
8 commitment
9
1 share
$308,143
$4,500,000
10
2 shares
$616,287
$4,096,000
11
3 shares
$924,430
$2,048,000
12 $6,144,000
13
BP (amend. 2 + new)
$2,568,430
$4,096,000
14
Chevron Texaco
$616,287
15
ConocoPhillips
$308,143
Total
16
ExxonMobil
$924,430
Marathon
17
Shell
$616,287
Grand Total
18
19
Total
$5,033,577
20
*MAP $15K seed money included in share
21 calculation resulting in a reduction of $1366 per 22 share
23
24 Sponsor Potential Payment Schedule
25
2005
2006
2007
Total
26 BP
$2,568,430
$0 $0 $2,568,430
BP
27 CVX
$365,333
$911,959
$434,994 $1,712,286
CVX
28 COP*
$548,000
$308,143
$0 $856,143
COP
29 XOM*
$548,000
$1,367,939
$652,492 $2,568,431
XOM
30 Shell
$365,333
$911,959
$434,994 $1,712,286
Shell
31
$4,395,096
$3,500,000 $1,522,480 $9,417,576
32
33 2005 pmt schedule unchanged from current schedule except for BP
34 * 2005 commitment paid as of 3/31105
35 36
H
lotal Commitments
$7,068,430 $4,712,287 $2,356,143 $7,068,430 $4,712,287 $25,917,577
$215,000 $26,132,577
Calc Amend 2
$0 $1,096,000
$548,000 $1,644,000 $1,096,000 $4,384,000 Paid through 200 MAP contribution
Page 6 of 15
4/20105
SHELL-MCCLURG-066015
I 1 2 3 4 5
J
6
7
8
9 10 11 12 13 14 15 16 17
18 19 20 21 22 23 24 lation checks
25 Amend 3 26 $2,568,430 27 $616,287 28 $308,143 29 $924,430 30 $616,287 31 $5,033,577 32 33 34
35 36 Program Total
Total $2,568,430 $1,712,287
$856,143 $2,568,430 $1,712,287 $9,417,577
$16,500,000 $215,000
$26,132,577
Benzene Health Research Consortium Budget as of April 20, 2005
Page 7 of 15
4/20105
SHELL-MCCLURG-066016
Benzene Health REsearch Consortium Budget as of April 20, 2005
A 1 2 3 4 5 6 7 UCHSC Expenses 8 9 EMBSI subcontract expenses 10 11 Fudan subcontract expenses 12 13 Histology consultant expenses' 14 15 Cincinnati Children's Hospital expenses" 16 17 IPHS expenses 18 19 UCHSC 12/31104 bank balance (subtract from expense projections for 2005 payment to UCHSC 20 21 Projected Expense Totals 2005-2007 22 23 Current Payment Schedule/budget 24 25 Total budget increase 26 Total paid to UCHSC as of 12/31104 27 Revised UCHSC program budget 28 29 30 Histology consultant included since this service is a subcontract for the DP/ME studies. 31 32 33 2007 costs for Cincinnati Children's Hospital did not appear to be included in Jan 2005 progress report figures
Page 8 of 15
4/20/05
SHELL-MCCLURG-066017
Benzene Health REsearch Consortium Budget as of April 20, 2005
B 1 UCHSC Projected expenses 2005 - 2007 and Revised Program Budget 2 3 4 5
6 7 8 9 10 11
12 13 14 15 16 17 18 19 20 21
22 23 24 25 26 27 28 29 30 31 Payment for 2006 & 2007 should be made by UCHSC (2005 pmt already made by API) 32 33
C
DE
FG
H
(draft)
2005
2006
2007
TOTALS
$1,217,148 $1,108,178
$406,114 $2,731,440
$ 862,823 $ 931,939 $ 407,700 $2,202,462
$1,676,855 $1,651,285
$159,600 $3,487,740
$3,000
$3,000
$6,000
$112,000
$117,600
$39,295
$268,895
$12,000 $0 $0 $12,000
(513,618)
($513,618)
$3,367,208 $3,812,002 $1,015,709 $8,194,919
$1,748,060 $1,748,060
$874,030 $4,370,150
$1,619,148 $2,063,942
$141,679
$3,824,769 $10,137,850 $18,332,769
I
Page 9 of 15
4/20105
SHELL-MCCLURG-066018
JK
L
1
2
3
4
5 API revised payment schedule
6 Apr-05
$874,030
7 Oct-05
$2,750,000
8 Apr-06
$2,500,000
9 Oct-06
$1,500,000
10 Feb-07
$570,889
11 Total
$8,194,919
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
Benzene Health REsearch Consortium Budget as of April 20, 2005
Page 10 of 15
4/20105
SHELL-MCCLURG-066019
A 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Benzene Health Research Consortium Budget as of April 20, 2005
BC
UCHSC increases EMBSI subcontract increases Fudan subcontract increases (new) Histology consultant* Cincinnati Children's Hospital** TOTALS * Histology consultant included since this service is a subcontract for the DP/ME studies.
** 2007 costs for Cincinnati Children's Hospital did not appear to be included in Jan 2005 progress
Page 11 of 15
4/20105
SH ELL-MCCLU RG-066020
Benzene Health Research Consortium Budget as of April 20, 2005
D 1 UCHSC 2005 - 2007 Increase by Category 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Payment for 2006 & 2007 should be made by UCHSC (2005 pmt already made by API) 21 22 eport figures
E FG H I J
(draft)
2005
2006
2007
TOTALS
$843,080
$843,080
$406,114 $2,092,274
$238,150
$562,550
$407,700 $1,208,400
$159,600
$159,600
$159,600
$478,800
$0 $3,000 $3,000 $6,000
$0 $0 $39,295 $39,295
$1,240,830 $1,568,230 $1,015,709 $3,824,769
Page 12 of 15
4/20105
SHELL-MCCLURG-066021
Benzene Health Research Consortium Budget as of April 20, 2005
A 1 AHS Case Control Expense Projections 2 3 2005 and 2006 4 Because of the need for much greater involvemnet of project supervision and QAJQC in Shanghai, we need to increase our level of effort. 5 Basically we have added 3 weeks of the PI's time and support from the others. We have also added one more trip to Shanghai in 2005 and 2006. 6 7 2007 8 Assuming that patient enrollment will be completed by end of 2006, final diagnoses and patient interviews completed by March 2007 and exposure assessment 9 completed by May-June 2007,we will be doing the following tasks in June-September 2007: final QAJQC, statistical analysis, presentations, discussuion with 10 Scientific Review Panel and Technical Committee, and report writing. 11 At this moment, there is no budget for 2007 at all. An estimated budget for 2007 is provided below. 12 13 14 Labor b~ categor~ 15 16 Category 17 Chief Epidemiologist (PI) 18 Biostatician 19 Statistical programmer 20 Research/Administration assistant 21 Consulting industrial hygienist 22 Total labor for regular activities (2004 $) 23 24 25 Meetings/working tri[!s (time & ex[!enses) 26 27 28 Meetings in China (10 days @) 29 Meetings in USA (3 days @) 30 Total for meetings/working trips (2004 $) 31 32 Total in 2004 $ (labor and trips) 33 34 35 Yearl~ budget estimates with a 5% annual adjustment 36 37 Additional budget by calendar year 38 Total additional budget (with 5% annual adjustment) 39 + original 40 TOTAL REVISED AHS BUDGET 41
BC
Hourly rate in 2004 $ $324 $162 $139 $104 $232
Hours 120 40 20 20 20
Unit cost in 2004 $
$34,000 $10,500
No. 1 0
2004
439,242 439,242
Page 13 of 15
4/20/05
SH ELL-MCCLU RG-066022
Benzene Health Research Consortium Budget as of April 20, 2005
D 1 2 (draft) 3 4 5 6 7 8 9 10 11 12
13 14 15 005 16 Amount 17 $38,880 18 $6,480 19 $2,780 20 $2,080 21 $4,640 22 $54,860 23 24 25 26 005 27 Amount 28 $34,000 29 $0 30 $34,000 31 32 $88,860 33
34 35 36 37 Year 2005 38 $93,303 39 441,540 40 534,843 41
EF
2006
Hours
Amount
120 $38,880
40 $6,480
20 $2,780
20 $2,080
20 $4,640
$54,860
2006 No. Amount
1 $34,000 0 $0
$34,000
$88,860
Year 2006 $97,968 450,263 548,231
GH
2007
Hours
Amount
400 $129,600
320 $51,840
360 $50,040
160 $16,640
100 $23,200
$271,320
2007 No. Amount
3 $102,000 2 $21,000
$123,000
$394,320
Year 2007 $456,475 0 456,475
IJ
Total
Hours
Amount
640 $207,360
400 $64,800
400 $55,600
200 $20,800
140 $32,480
$381,040
Total No. Amount
5 $170,000 2 $21,000
$191,000
$572,040
Total $647,746 $1,331,045 $1,978,791 1,978,791
Page 14 of 15
4/20105
SH ELL-MCCLU RG-066023
A 1
2
3 4 5 Blue: Fudan budget reanalysis, through 2Q 2007 6 7 Labor (time) 8 9 Category 10 Physician epidemiologist 11 Data Handler 12 Total labor (US$) 13 14 Exeenses 15 16 Fee for Shanghai CDC staff 17 Fee for AML patients 18 Fee for NHL patients 19 Hospital coordinators 20 Fee for controls 21 Fee for NHL hospital coordination 22 Fee for office supplies 23 Transportation for local and long distance 24 Total expenses (US$) 25 26 New Exgenses 27 Add transport for annual mtgs 28 29 sub total 30 5% Annual increase 31 Overhead Fee (15%) 32 33 Grand Total 34 Current 35 Increase 36 37 38 [*Annual Salary includes salary, bonus and benefits.]
39 40 41 42 43
Benzene Health Research Consortium Budget as of April 20, 2005
B C D E F G HIJ K L Fudan University Case Control Revised Expense Projections (contracted directly with API)
(draft)
Annual Salary* US$
16,900 5,850
Unit cost
30 30 30 30
2004 52,170
2005 (Year 5) Time Amount 0.15 2,535 1.20 7,020
9,555
No. Amount 6,000
150 4,500 150 4,500 150 4,500 600 18,000
5,000 1,800 1,200 45,500
15,000
70,055 0
10,508
80,563 58,356 22,207
2006 (Year 6) Time Amount 0.25 4,225 1.16 6,786
11,011
2007 (half-year) Time Amount 0.15 1,268 1.20 3,510
4,778
No. Amount 3,000
130 3,900 130 3,900 130 3,900 460 13,800
5,000 1,700 1,200 36,400
No. Amount 1,500
65 1,950 65 1,950 65 1,950 230 6,900
2,500 900 600
18,250
0
47,411 2,371 5,709
55,490 49,015
6,475
15,000
38,028 1,901 5,989
45,918
45,918
Yrs 2005-2007 (est) Yrs 2001-2004 (act.) Revised est. budget 11/03 budget budget increase
$181,972 $124,090 $306,062 $230,000 $76,062
Total 8,028 17,316 25,344
Total 10,500 10,350 10,350 10,350 38,700 12,500
4,400 3,000 100,150
30,000
155,494 4,272
22,207
181,972 159,541
22,431
Page 15 of 15
4/20105
SH ELL-MCCLU RG-066024