Document gaaRKyRY6wgzRwJ7Bq7rDOa63

V-;* ft 3 ^ *_- ABSTRACT OF THE LITERATURE OF INDUSTRIAL HYGIENE SUPPLEMENTARY TO THE JOURNAL OF INDUSTRIAL .HYGIENE AND TOXICOLOGY VOLUME 20 JANUARY, 193*--DECEMBER, 1938 . PUBLISHED BY THE WILLIAMS & WILKINS COMPANY Baltimore, Md. 184 JOURNAL OF INDUSTRIAL HYGIENE AND TOXICOLOGY (wi. *o, M, Anaesthetized eats were given .intra tracheal insufflations of fine bismuth car bonate, bismuth subnitrate and lead glass powders by means of a powder blower in serted through a bronchoscope. Fluoro scopy and roentgenograms demonstrated that in the dry state these radio-opaque minerals were not earned into the terminal air spaces but remained adherent to the walla of bronchi lined with ciliated epithe number of cancers found is a very high one Of these 6 cases, the site of the cancer in cases was the lower lobes, in five there war a squamous-celled epithelioma. Three ol the victims were less than 43 jv*. old; in all, work with asbestos had begun 15-21 yr*. before. After all, the author seems quite right in seeing a causal relation be tween asbestosis and lung cancer --L Teleky. . lium. The process of removal could be readily followed. The column of dust on Cukicxl consideju.tions ok the oczstion the mucosal surface moved upward with a O IKBUSTKtSi CSKCZa O r SSBZSTOS spiral motion. Neutral bismuth carbonate t/woKEZas. F. Hamit. Zltchr. J. Krebs- was usually completely eliminated in 1 to Jorteh., sol. 47, pp. 331-tST (1933). 4 days, the acid subnitrate was excreted slightly more rapidly and the lead glass had disappeared in from 7 hrs. to 2 days. The reaction of the mineral did not affect the rate of elimination, a result at variance A 35 year old woman who worked in as asbestos factory from 1919-1928 fell ill of asbestosis; in 1937 a sharply defined shadow was seen roentgenologically in the upper lsft lobe. This shadow vaa considered by the with those of other observers. If the par author to be a carcinoma and in the decision ticles were suspended in fluid either saline on the case, a causal relation between the or thin syrup, they were carried into the presence of asbestosis and the development terminal alveoli from which they were -of carcinoma was accepted. Confirmation slowly excreted by the bronchial route over at autopsy of the diagnosis of lung car periods of weeks. No evidence of drainage cinoma is presented in a paper by Nordman to lymph nodes could be discovered. The (preceding abstract).--L. TtUky. authors suggest that inhalation of dust in the dry state might be leas dangerous than if it were moist. The presence of sufficient amounts of water might permit the mineral particles to penetrate beyond the protec tive ciliary epithelium and allow gradual accumulation in the lungs.--L. U. Gardner. ExrxKmr.NT.ii. hcvzsttsatiok or xxx SCHNXSBKRO LCKO CAKCXi Q7ZSTI0K. 3. R. Dihnert. Zltckr. f. KrebsJortcK, col. 47, pp. *09-139 (1933). In a very exact manner, with regard to the pertinent literature, and with careful con OocoranoNAL cakczz ur asbestos woke- sideration of all factors, the author reports ebs. M. Nordniann, Zltckr. /. Krtbt-. on the tumor* found in mice kept in the Jorteh., pol. 47, pp. 333-303 (1933). j Schneeberg mines. In the experiment were The author reports on 2 cases of lung1 48 animals of whom 28 died. Of these, 26 cancer of which he made the pathological- were given careful pathological and ana anatomical examination. He reports like tomical examination; the other two were wise on the clinical aspects of Homig's sent to another Institute for examination case (see following abstract) and on a 55 of their radioactivity. In 7 animals, yr. old man who had worked in asbestos tumor* were found; in two of them, multiple from his 36th to 43rd year*. Autopsy tumor* in various organs. Since the experi showed asbestosis and in the left upper lobe mental animals came from almost tumor- a markedly necrotic, comified squamous free stock, the number of tumor* found is a celled epithelioma. The author mentions high one. In two eases there were true 4 additional cases of cancer with asbestosis epithelial lung tumors, in two, ulcer* of tbs in the literature and one must agree with mediastinum, in the other 3 esses there were him that, in view of the small number tumor-like, more or less generalised changes observed and the very few cases of asbesto of the lymphatic system. After careful sis autopsied (12 cases in Germany), the consideration, the author blames ths re-