Document gaVy0Op6DOr1b14kVzvxObd5L

Attached for your tnforaatloo ere coplaa of tvo recently leaned artlclei that will be of lotereat to you. *! Tint 1 the report frca the July 3> 19^7 latue of Cb*lcal Eclne*rla{ reporting on the ATI atudy of the cca*.> of rnxrrlng lead frc* gaeolln*. , You vlll raaaafear that durlrg tfca Kurile Hearing* of June, 19&6 the ATX prtmlted definitive etudy would be eade of tha ecooculc* of renovlag laad from jaaollne. Tha ti*iy vu aade for tha API end flrat reported la May of thla year at their Kld-Year Meeting. Second la tha raport co tha VHO tixxfjr of lt*d la blood aa It appeared In th* official VHO Chronicle for >My, l#7. Tou vtll not tea that Trofeeaor Coldwatar locludaa la Mi report tha retulle of blood maple taken froa See Ouinee. Vary truly your*, I MT/jv Attachment* (?) tr*J& Don 0. fwler Director, Health and Safety || i.g; nm ij w .fq^jureengi* s-3'*' -Sit .JuL Unleaded gasoline--boon and burden Lead compounds In gasoline mcy or may not poso health preb* Urn*-; but In any case, an Indus* tor-sponsored stud/ points up the drastic effect on petroleum rcf.ning that would come from a decision to outlaw them. Til/ the future melorUt wrko Ufi unleaded yaaollfie, and the re* tfcrr7 that make* *och a product. U would mean atafireriny rot* to both, accord *&y to a report pro moted at the 2r.d Midyear Meetlny of U4 AnrrlaA IVu^jra ts.t*- tle (ATI) D.t . of rUf.nlr.r. held la L04 AnyrWi ia M*y. The APl-*poo* *e<cd tludy. toe*doctcd by Roarer and Mvre Awi<Uio, Itr, H^.** ton. ttlU what happen If or* Uoe*beoellay Wad add. lire*, loty oe~u*ed of Wr.c a M*rtj *f Um<o* pUf*t ^*eT-*.M.n, rr* tanned frv*a OottrreT^al tsUer y*ohnr*. JWaad rtd.irrt *tud* W* *imd at prvidi*y a rralutie ( ^a IOt v mU picWrt, UMuxr a.'U M*re arrfrr* at a Cr->r of IIS b*oo/yr la added {<*+ (tuU for I'A EMriU. T)a ftluity aWo indl* cau* that nalWawida tM;vrr<iea to VnWaded yaaaEo* wvwld retire the r*nirwtW af 14 2t b*r.ew *f ad* ddWaal prectaaioy oaiU capable af ru*;; hiyb-ceUne yvaoli^e with* 0.1 Wad. Thi# Cy*re more than <*'S of the rarrtot yre* ioT*t.<reot la re***/ tAr^yn-Mrt 1v~# D avS ia a )$ t,>a#* hi;>*r ;>*n !-# aTfr-ir# Tee/'./ *.t *r t-f 'P**47>\. * * >1 y.i.-t'*, K#r* iff *-;V/ fa-?#;* of \be t* f**J, a* Vt Ue * >tw# !// u *+**;<i to r*44* t^# *#v ;**--.;*--* b'-d h`^S ta a^4 U-* i* Tai* * `*r;/ ff* .#fc*at r*;.,*# <r-1 * *.a im/r** >f il`* i* UA. i.fti.M.>* .' trui* *1. The i4V.'-ary p/iy.<i*at that psyi.4* i*.U4 !n<.-uu 4..U (yt>U4iU ,<* r,w (Mil/ U^a Uw r-irt^Cj tA.4 the hlyh per-barrcl coot of amnU unit* restrict* the ut of the at proc cuci to Ur/* rcfnerlaa, thereby putSU/ the email refinerie* at a dlaadronUyt. 11 ii r amount* of platinum cata!/*: .r needed to make un leaded /aaotioe. DUqwletlr.y *a the*e facto arc, there l* a food chance that they rr.ay ftcr poae a real threat. Erea thMfh the old controversy of rUlaf atnwtpheric-Wad leie! aa a reeu't of car <ahaa*t cmitalon* U far from dead, there t now no pecU) urye 04 the prt of yorcramefttal health* A/rneW* r tnd^try to briny about a ma.fct.re v.uh ta nW*4cd fuel*. The f^r thU U that the par- tie* !i<~v*d la the cootroeer*/ rr!iir th-t a fitui wJ canoot be aid ut:d all *pvu of the prob lem hare Um probed further. At auf rate. It aerm* certain that lead y**--`r-e d-!<fc 1o *to/ f^mlWa. to a recent ro* * rmi air po*",<#U ira^ ^ept.:r*cc. p. ^4), Lu l .V Dept, of Health. F.d-catfOft, a&d V/#.fare fl!DW) U<eJ that (MultfiHk e ycar-looy te*U toft* ducted by t>a feat oo tale-mode! pa**#*f#r care t`t&.t.j Waded and WftWaded fl. Bat Waa* Ue le*U Vf,*t iv, corceroed .th dl atpecta of Wad ee an mrimretUl haie/d, Wa-Wd raeodoe o t <%%lte yet a eWaa W* of heeaU. The report it* aelf carried tome dlecrepaBclc* botwoen HEW And Du Pont over lot* (nf methoda. aod called for more research to aetUe the Question. PA >ta**Ire EJTort -- Since the early U'.^a. when rcfncr* aurtod putUr.f Utrathyl Wpd (TEL) Ut* yaaoliAtt, much koowWdye ha* teem accumulated oo the ue of Wad In fuel*, and oa Wad*a effect oo the human environmenL VarlabWa each aa the ooouot of lead in city air, aod la the bWod and wrlr.e of people who work or hre to urban arena, hare b><a mcaaared tia^e &r-d ayaia la the *earrh for meaningful trend*. One *u<h *tu4y, pubi*hcd la 1PSS by HEW. oUUUUJ that there *m no ccrui*tnl trend, up or down, ia the Wad tonudt of the air of three ciuca (CiAclaAati. rhiladtlpMa, Loe AayeWe) durlay the prerioua five year*. Nooe of the coacentrotWoe found were lha*yht capabW of pro* d^ciay Wad intoaicatWa in Ifdi* viduala. D#t |w#itrgver*y w*a ral*od ayalo bit year at Senate PubUe Work* #ub.'.5jn.;ui hearts;* oa air poWuoa (CAr**. E*y, Jaa. SI, 1>SA, pp. IS, 2d), wkWk featured fee* phyaWiat C*atr Patter*09 a* a etar w/.oeaa. PatWroo* aaid hit reeoarth ahowod that Wad la the he* c u a envtrwomeat vu raachlay ertt* ical WrreW. d*ai how erttwa! theee htiii were rttuise ^^*#UooabW, aloeo a i Nxf.rw-j/` hili>t j:j rn i! gj4- n* h-i<J U Ut ia*v iA4 0** -'-j L- Aui# (*** '<* l MlJ Vw.lHlwl^ C** r***i I U. -*4 rf a *4 / #i e# c** -*o *,irt T*U f se*u**fc/,f#. r*V 6*^44 # C*A -a- t.ii .... C. 1 Uh ......... ........ Cl"-....................... .. Tn*i U V.......... . *;a .*/o * 10 .uo *0 w 1!3 to avS ]}0 to I.U4 >0 2.1 M ii -fv- - i Vf : ir'r J. .! t N 500.01 mint rt;>r*<ntAliv rtfincry tonfijr* urAtlo.io that reflected lr^4rl rtrl* Atien* In geographic locAtlon aa4 :-K<?fe! Ii . The*# rcprcwouilvt rcfln#re were the Lxxi for nuthemtticAl modett Out tlrm*Uttd tb manufAC* r' tore of u*in/ lead hull* kne^k &t!i.tSvci. \Yh#u m*Lfl*<L th# ab*V isyw!eU ftbowcU the Inert*** In c/uti when tec.4 odditWe* wer* tUm* IfutcxL Li .v a t programming w aa uted to obuio th rtuItA, Thf rctcorcbcr* iWr!(pc4 two 0/ mor Ttttecy ia4tAUor^ for t*ch rfAgraphk rtgUn (Wet CoA*t Mttt-Coouwnl Arfi. Ea 1 CoAt Aiui Cuif Ccu^l). trui tw^Jro r#/.fvcry - $: roi ickftol for inut/, Alto* fftttor. About Julf at aU UJL ro* Ci.tfM* Wff< icrfiouc*! in tho group* U; t:ut rcfoUc^i U tb* n**cf ,n-. jUtiooo. > of tb# prvr#o*4o Uut w*r (otuiCrroi for toAk^og tbo u&too<io4 ;sr gAwUof ort tn 00V baited Knkl Xa^xf. Howfrtr, tht rtMortWt c<r*ui?k tbit they t#t in <o<n- is ;i iAt mi f^:Ut/. Atr-oAg tb*4 wire: klgb* r<r^.u*.ix. arosutic m* lAtit-n. f-'ffto dlt* ywo;-w;.w-i:.on. kyii/oirArkt^g, aa4 bApklX* AU>B^rorkiAg->4Jl ' yw jn r * 0 * i<WTii^ iy nip;w wy Jit ^OCAAWl, KO M ^4 U 1 ******* U4 >HW4 4;i |/ IM */ OC*T ^4AU) Chcmlcit Industry Draws on 4A) (t-*4 Id '/.oro and .V.oro D^^eec* ttJk}*/ *f*d *f Al lid }+//< U/ i* ,*/>>*>.*/ |?vo *& f t >4 rx^# tr~i bl-o^j/:.*.* J Vti A iw+4 b/ U4 13. fy** ; )>#* .' /<| tbt *. %'t !-ftl W!*o {W *>4 of V-4 `*^ x of *b.-I. ... 4 i\*,,,*r *n*4 f'- M4 |># Cc ;W* W*4 >Yi W . 4 -<>l p T&* #i.J 07*f tVf 4-.' *;'>/ a-*;-.*'* *f '**; w, *},'. *.:*.*.,;_* m \V-*\* #,*1***-*. fft.JU* At--* t'* l**t b**r . *>#, t* A'rA* ^"H-4. T A4 Mv/ O**A. t 0*.A W<3 U v',`t 4 t+A.b~*4 f*V Ht*+fc.4f*l U`a {it lb.* n.ty. A*i it ** of U* 4-s/ * j~*MW of r**4'0*4k+wtk U4*/ AI 1X4 M.-f/otr Xfttiitf, ATI 4 p/t^mt (f>n +* Mvt/tj p?*;*tu t>-oi A/t r)3*rt*J with: t*Uw-kiAjf A it/ *l*r,,i.tfu fo/ UJ (in Ai'i-TIii J>JM pfo/r*sn) ; rr* -ftti-V i> po- ta _l< '. V* <.; t ri ;k A-1 i,*r-^} t<Mtj; dt',4( r-,f..f. >.0 tV . *r , ,/ l **?< to K#>/ J. .1 u{ A V' ft.*..- t-* *.*. /a *. 1 *.-* t>. ; J *' !'* t-+** + hr,-] if **, a i rS> ^ lout**'.*'/ r>lf# |--V' * ^OO/t t. mf Wfcl rr**# 4* pj-lt of i.*4 ovir-kii t.'-ii, trot it *30 tbt fr>i U/*i Am tburowfk IhmlifkiU4 Ia U l>4 o<%#wfnU* of u aUo U<: f^L Tri#b*4< iu;; p.04 tti U Tor rtry Ua <A/to<strA In lb# vlk !Mj*irr a^w , tktrt w>Li b #;< #.' >0 } )7d. Wn*t`i r&ort. i.-t I>T> Wri bt m<rt tbn trio 0-r.i o tV# fcufr-Wr of |t*-o f.vri&4.fct ifci-*i/y jTt t' bfg.AOiog of ik. * -Mf (^it, ;# Vh 4 t n'..k.-.ri i*r rs:rw<*iu ;\<i f.M. a i t% * * it. `-.^' *, ' > > l*rn *.>. 4*5* frr, l -r V 3 Pw* i4< L*v-r it?*5 ', *'* ] tf 4 t-4 l '/,#_>-** jo.fti -/ r.o* T*v* *;,<.Jt'>r *V<v ff'ii* f*/ U-V*i. b0.^0 fir tlr7, > f*r !>?, "bf b JTMf* ?>/H< Ml (*<r.4 i>wj 0*4 iXA, o>,u t?. ror.ki from 3X*v4 t 44 1->X T>-t t(*i* prt* i^u4 f*r 1**4 t* 6i,v. M!LLLi.U^^w*'1** ^*<i *** rtw i 4-^.^ 1 * ' iUtlifclkiaifrf* MillWiMM&'liiii '* / " ....tV rl C 'Oirt.-H' Xi.r t /j f .j r. "NORMAL** CONCENTRATIONS OF METALS IN URINE AND BLOOD 4/ Professor Leonard J. Goldwattr of th< tt-ify. * oonr.il" *a defined at it* 1$ ** W IV //a 7 coeorot'AiiOtri oi thox Ktua pfti-cl ia it* M MM <//kWl Mfctefl i iV /*#*****#, biu* od blood of individual* U h*4 h*4 f*7/0 yut**t+4 m *M{r i/ oo oovpuo.il. 0t*ptut(C, of oOicr dttnoo- `4 vw/ iVf 4/ ^ i*a km^m Uf.S'i npovfa.*c to tel U*f/. ,4 nrrf*V V ^ 1 >4i VI/ * W /4i) mrklt Lmi Kfm j^Yn*J/ ns'* A; fV CUmn /<W <vf**<.vV (V It* ISucc&i-Goxnl of WHO jni|ul(f tif UN>:ioo of it* t>.< .woo of (Xvupot>oiu] S<twuS of r!wc llfhtk *j AdoiuJtiMidlor. Co Cj .t .Va Uoi* vm-ry. at a left.-core Utouatocy for I of ittit Luui. i uurk'oj n.,-port gtuinol TL* cLr.k?J w(u<a!ftj:*a 0/ *r.*A* pr-vips-fy t-.< l i fVi-c Hcaldt ffliiroASVA: kil CiWCffl Vcf>:t >f4 p-'"> fiw WHO. r*Ct&! ):v. Ti-J *vf Ui* MK^J A:. kf iu*J* soil trxUbo- titf ttX Irf W* pr.lN> S fj-,,s; UtvfJWi'o >4 t* lovatii * t tofot i j*/\vm*;. ^r*^rt;r.^ kswJ- cf w.v; i.~ tlo-bd ia *1 w rj te !;.*% A% p-- SX' J-- --'vI cAccvt. b) tx lo Cov'.- v - y SSit U* IAt;bwui 4^2 )>r.; {Kvj<^ bri UrtA S(1C ,V. .\-fBHtl, It* 1-1 /loo cvsvrrv^nJ.*.^ tr>vHf 4*unuia ih& Lay * Uo li* uc-pte BI obu.lwd M WUifH *f U* 0kt cLfTttkC*X bvt lb Ultff a rd^m u/p' of i!* jvpw Cir.r,^ U orJolfiI. U`4T.I to It* f.bi (U (uWtUiO, bvl ttrf) Roc*;tcrLa>. lS 1<t .;v *u j k crft\UKt>tie* io 'Uo 1 BtrSni of both KU1 taS r%tl w*t vf bnw lit* tf< t'< W *4 uiM rrwfola hfi*X IWU!* m L\ l^.Tj^r. UW/. WHO* iA ce^WfA-i-x) *u?i Cfu*tf*ty, t*4 Nr Ye?*, tmUAUt* iA iHi w-Jj of iJ* ftocttil of kxl. N iw/, e4 rmU ii w^.i KJ< fo* :U To obtoia *0 dri of l.Vr Utour i of IriJ pfrwai to humoa Kim. vl-j w p,.o *111 or.*.'; wd- TfO *,--.>jCli pir**! f from W l>-t ) sf t- HI r./ ;-t > f'r* of .>* __ *1 i-f fr< 14 t*..*.'! t p-^n t4yf4 fron a y of Si i'i >',1.1:^ io ^- fco'-.i *. "! of i; i il l.n . Prfo It* t w f iv i`-4 .-< n< 1* si ;s t,rb>.i f-td'/l <4 ;'! t*f *1 *S,ij b-J>0( It mU t`*J pri'plj f:,i f'! t,t 4l i.nlt d-'r.-ioc* Sf.<ro ai.-ri #od W ( >--- - -----U it *_4 v W At * I^Mn oa | -> f is.1.1 vv *- 1 /M I 'n..1 `- >*J'wiW-r^^-VLr!l,~^:irr N 500.02 Ii 4 I % i I .5 i I I "1 The concentration of lead la the blood vii found from a itudy of S16 tirr.pfc*. The value* racked from Itii than J , j up lo IOO^j of lead per ICO ml of blood. 7ho hiphea mean b!oc><l Icivl. 26 ICO mi. UJI found la aaraplc* from HcUi.-.Vi. Haland. anJ if* knelt. 7 j -j /103 ml. in the I'cruvian varr.p'.cv, while the mean for all aair.pk* v 17 ,.$/ 100 ml. A* wilH Ihe urine tlrrplr i, urban level* traded lo be tliphtfy -Ypher than rural, and there ai no appreciable ddfcreooe bet-cm Cm ion. Not included in the itudy ucrc J$ blood urr.vo obiai.ncd from inba'sianti of a znousuiaou* area la New Guinea. Thi* poup Wat tclecicd became of i'.i complete absence of contact u.th motor itl-icie* or other potuhle man-made lourrc* of lead. It ik of conudctablc tnurc*t that the lei ell of lead ia the blood lay between 10 and *0 rli'iOQ mi. with a mean of 22 ;C0 mL. H.d'jer mean value* Cat tin* were found 0*1J la I>j and. Kialand, and Vul'ditta Three *:-d.r* cor ;rr>^c rr; . :t* on tl* uNjatjf of ltd Wtct tie r.kultk are <u., ./id i;j* Ibotc cf *r.n.da *i . C.C* la lndtdael ct*-r;r.rt trade la.r p I-** pa it tC.ni Jceadct. lla, j it t.n--'Value tpirnerot la the tar pr* and rrri.j P.' it* eonceotratiou With repaid to mercury la the blood, tho prevent itudy--bated oo aa analyiit of 112 blood uoiplca--ii the ft/a Urpe-tcale HTort to eaablith a norma! level. A zero reading vii obtained for 7-t *' of (7* aampfe*. and a further 70 V contained lett than i *.g/I00 ml. which Cpuic may be taVta at a rcatonable tipper brnii for mercury la the blood. Agaia. there were no important difference* according to tea or degree of urbanization. Arveate Owing to difficult** |a analytical tech* nupue*. rrf-able mufti foe arurnic ia the blood were not obtained. but arvcnle in the urine wat determined ia AJI tpccienca*. with a acnt-titity of Ir-tT la e6*c \>.< utpln tto ftrvtuc covU b** <U*AVi, *.'4 ia f~j\17 *' iSc k>rl Wi* If** tUa *5 T>-*k Urtft tfut may Uua b CvCi-skr*^ 4i tW Uavt oC Cxcttfii-4 Kaotf, it h La>a that U* 4iv^ o/ O. pvir rr<jZt ia U-rfl* C\' ifin Vfi*^ *a/ i4u;w f;T*x:i. Jun w<. t* f*ct r^we t> *a ICO 0* K**#< jWf Ut* U* tvaj i)0 ^|. of lead in bud* urn* and blood. Mcrcuejr Ana'yur* for mercury *rr pe.-fj.n-.cd by a very Mi-mi metV-d capable of P-cam.-.op at Lt.le -i 0 ) /.; per Ui.-e of ur.-te or per ICO ml of blood. Cc-.vr.!ruoot below if**e 6.r<t are recurdrJ at *ro* lie w tptoi-.xt tef.ed for mercury Oombercd 1101. Of line. 77*' Jute* zero toneerst.-atoo. a.-ij a fat; her I7v eoiva.oed let* than 75 t-p u 71.* fp.r# t-upbt tattoo. ably t> a..<;-;J ai |.`e upptt !.v,i of norm! toivinr-uM, t-1 value* VoulJ |j;;n! an u-.i.ii upv, 7.'era ' ir .put ,* uce .1 .T.r.'an let-1< *. mi et n-J frct-e* or be:*nr* urbaa and tural dathttu S*cc l^ MaspSri ff tx* K.VbW c*a 4 *uui:<*Jy t (>-4 (4f>,Wt bc MtaClUrie'/ lO LU t v x i n4 iSiiSal ffiffjli cChVuTUXb- H*.I l>xjr pyf aa >vV* ^ T3x &( 4 Uri fi Ki t^4 c^t to lh4 ftUfet id fc^vaM ruy K# *Vk >c Sa^ tU ,'iwnj a i.Vt ll i id K*?l mx "4 K>ft o/ Vt (V*:| 5er;Z* If .* *1 t'tf mm ta InOo I mm*> I*f fiM * o of iw>*h* **;>-* v'/4 l*; r*% ir> wf^** l?X; a-b4/ af >*ier* ia 4 f* leadAt. n7t<U- M r ' t--\- -. v ^ ^!gy?.,|J-|J|'i;J'' w|Mi`g5jy**ay.4wi.t J"ll*L i 1 hi,1;*-*- j t.