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Since the U.S. Surgeon General's Office has raised no objections- to the marketing of TML as a substitute for tetraethyl lead (TEL) in motor gasolines, several, questions related to commercialization were discussed in turn. " Pump Markings Dr. Kehoe believes, and others present agreed, that changing the wording on pump markings from LEAD (tetraethyl lead) to another form which would cover both TEL and TML was not a problem of immediate importance since the same cautions concerning use of the gasoline will apply and both compounds contain lead. There are no state laws regarding the signs. In addition, there is no worry over so-called "antisubstitution" laws since a product of superior value is being substituted; and there is no intent to defraud. It was concluded that the changing of the signs is an "industry" matter and will be carried out gradually as a routine "maintenance" operation. The Surgeon General's Office originally designed the current signs and has been asked by Dr. Kehoe if it prefers any special wording on the new ones. No reply has been received as yet. Conferences with State and Local Agencies Dr. Kehoe planned to visit the Los Angeles Air Pollution authorities on March 14 and the State Director of Public Health on March 15 to review the Surgeon General's decision regarding TML and answer any questions which might be raised concerning its use in motor gasolines. Dr. Kehoe also plans +- n>gd-aa- .a-- r-jpf snfr Spring., Tp^hUtfud? Long-Range Studies-for the U.S. Public Health Service j 7 The Public Health Service has suggested that "one year after initiating the substitution of TML for TEL, a report be prepared on the impact of TML on the contamination of- the atmosphere in a major metropolitan center, as well as clinical and environmental data demonstrating the safety of controls in manufacture, use, and handling of TML and of gasolines containing this compound." Dr. Kehoe is preparing what he considers to be an adequate program for this purpose and will meet later with members of the group to discuss it. In general, it will involve quarterly physical examinations and blood and urine analyses of company employees involved in blending and bulk handling of KE 0003048 leaded gasolines. A number of field personnel, such as station employees dnd garage workers, will be examined and sampled semiannually. Dr* Curtis and Mr. Spence in cooperation with Messrs. Porter and Houser will determine suitable locations for the studies. At the next meeting, a program to obtain additional environmental data will also be discussed. W. L. RICHARDSON :lra j r m -6 File-5 0003047