Document ga0kV3b6M19XdOBLa1oMRmVG

N-` * FLU -0)0' Part VJ (7/6B) -15- Prot1cct; * Electrical Fluids - Part VI - Air and VJater Pollution Control Objective3 : 1, Follow developments in analytical chemistry leading to more sensitive and specific, methods for identi fying Arociors in oar environment. 2 . Keep in touch with laboratories doing research on environmental contamination by Arociors including Universities, FDA, USDA, Fieh and Wildlife Service, 2. Study present methods for disposal of Arociors and if necessary develop safer ones. H. Assess possible toxic effects on humans. Justification: T v * ^ < 4# 1 4 A ^ ^ A ^ * 4- V ^ ^A.V J V. W i;^ a VA % 4. ^ i M 4 % i l f u V W U V A ( ^ U U X V 14** Ecctioid.es, bicchemists have isolated unknown chlorinated hydrocarbons which they have tentatively identified as chlorinated biphenyls. These have been shown to be present in some fish, birds, and vrild animals from certain areas at concentrations in the part3 per million range. Public health authorities have therefore felt that it v:as necessary to determine whether cr not environmental contamination by chlorinated biphenyls io a hazard to human life or health. It is vital that wo cooperate in these studies so that we can be sure that the results are valid and no that we can assess the impact of the findings on the Aroclor business. V/e may need to cooperate in developing disposal procedures v/hich will not result in harmful contamination in order to avoid restrictive legis lation. Status: ` At present, we are collecting all available information on this problem, The Medical Department is following the toxicology ar.d will start a test program at Calandra Labs to dofor:,ine biological effects of trace Aroclor. Res earch will evaluate the validity of the published analyti cal identification. c.m?2ec of Arociors, and in come NfcV 031106 780644 )' kp'" ... . ` : : i y i\ o-:\t -?-. ^ijyrsr I -- / /,/;j, r ^ | (I J _ i | * *r-- , l / / 0 r / K! ' " / T f *A. * {1'' c!:'"V -- VI (7 / 6B) - 1 6 - "*<*yJ-/U>- '`v.t[.{s-cLI'iIc.iV-'.J, Tf- 0 .-w.. !., Status :__^ontinuodj^ cases of pure chlorinated bipker.yl isomers are being made available l;o government and university laboratories working on this problem for use aB calibration standards. Plans: Responsibilities ^Job Target Date REK/ST t.'\. !r:i)rC Assess validity of analytical 'S 5/69 iy methods used by workers in this field. WRU/EV.'/ST . Collect information on all % work being done by others In this field. Continuing 1 / PB/JB/PH REK/ST Elmer Wheeler Determine present disposal methods for Aroclors. ;A Toxicology * Review v;ith govorrnent agencies, Research Institutes, (y,Start outside test program* 5/69 8/15/6 8 Manpower Assis:Rents: S.v 1C.<--Z Total Man-Years 1968 1*. " T i f . R. E. Keller/Scotfc Tucker VJ. R. Richard Elmer Y/heeler/P. Hodges P. Benignu.s/J. Bryant 1.1 #1 .5 `Estimated 1963 Costs; #25,000 (Calar.dra Labs fo r *68) #25,000 (Metabolic Study) Job Ro, Applicable 1650228 Sponsors: E. V?heeler/Scott Tucker P. Boni gnu s/E. K. Munch J u ly 18 , 1968 NV 031107 780645 (i r%k.. n ' t . * *1, p,, jor - . ].ouVs September 1 1 , i960 . ce Ur. K. Ii. K e l l y 1)2*. 5`joLJt Tucker V2..i preposea Protocols f o r /Toxicity . ... r*.* ... ^ : y r ; S t Iciloo a t Indus t r i a l B i o - T e s t , 1 / 2 0 . __ iir. Cm..:..l ''ion TO Ur. V/. R, Richare' Attached Is a copy of a letter from Industrial Bio-Test and proposed protocols for Aroclor tcxicity studies. This arrives just as I an leaving for two weeks. I will take this material with me and if possible send you my comments before the end of next week. If it appears desirable to have a session with Ur. Kelly and Bill Hunt to discuss this matter before I return, I am sure Ur. Kelly will be happy to see you.