Document gRvpzmmObdZn765055zn2w8V

Federal Department of Home Affairs FDHA Federal Food Safety and Veterinary Office FSVO 21FIPF Trace level analysis of per- and polyfluorinated substances in fish in Switzerland - preliminary results PFAS-Austausch / November 9th 2021 Alexandra Jaus Federal Department of Home Affairs FDHA Federal Food Safety and Veterinary Office FSVO Objective Determination of per- and polyfluorinated substances in fish muscle samples from various lakes in Western Switzerland and Engadin Comparison of the results for the different species, lakes and regions Trends over the recent years 21FIPF Per- and polyfluorinated substances in fish - preliminary results Alexandra Jaus 2 Background Legacy PFAS (Examples) PFOS PFOA PFHxS F F F FF F F F O S O- F F F F F F F F FO F F FF F F F F OH F F FF FF F O F FF F F F O S O- F F F F F F FO Federal Department of Home Affairs FDHA Federal Food Safety and Veterinary Office FSVO Emerging PFAS (Examples) F F FF F F F O F NH4 FO O O- FF FF ADONA Cl F F F F FF F O O F S O- F FF FF FF F O F F FF F F F O F F OH FF O 9Cl-PF3ONS HFPO-DA 21FIPF Per- and polyfluorinated substances in fish - preliminary results Alexandra Jaus 3 Federal Department of Home Affairs FDHA Federal Food Safety and Veterinary Office FSVO Fish muscle samples from 2020 (Western Switzerland) and 2021 (Graubnden) 18 3 19 30 (Lake Sils) 21FIPF Per- and polyfluorinated substances in fish - preliminary results Alexandra Jaus 5 Analytical method Federal Department of Home Affairs FDHA Federal Food Safety and Veterinary Office FSVO Digestion with NaOH Extraction with acetonitrile Solid Phase Extraction (SPE) ....followed by HPLC-MS/MS Sadia, M. et al., Environ Pollut. 2020, 263(Pt A): 113721 21FIPF Per- and polyfluorinated substances in fish - preliminary results Alexandra Jaus 6 Federal Department of Home Affairs FDHA Federal Food Safety and Veterinary Office FSVO Fish from lakes in Western Switzerland: General PFAS detected in all samples! PFBA, PFPeA, PFHxA, PFHpA, PFOA, PFBS and PFHxS only present in traces Emerging alternatives ADONA, HFPO-DA (GenX), 9CL-PF3ONS (F-53B) or 8:2 FTS not found in any sample 21FIPF Per- and polyfluorinated substances in fish - preliminary results Alexandra Jaus 7 Federal Department of Home Affairs FDHA Federal Food Safety and Veterinary Office FSVO Fish from lakes in Western Switzerland: PFNA, PFDA, PFUnA 21FIPF Per- and polyfluorinated substances in fish - preliminary results Alexandra Jaus 8 Federal Department of Home Affairs FDHA Federal Food Safety and Veterinary Office FSVO Fish from lakes in Western Switzerland: Total PFAS PFOS largely dominant! 21FIPF Per- and polyfluorinated substances in fish - preliminary results Alexandra Jaus 9 Federal Department of Home Affairs FDHA Federal Food Safety and Veterinary Office FSVO Fish from lakes in Western Switzerland: Total PFAS Median 17.5 g/kg 11.5 g/kg PFOS largely dominant! 21FIPF Per- and polyfluorinated substances in fish - preliminary results Alexandra Jaus 10 Federal Department of Home Affairs FDHA Federal Food Safety and Veterinary Office FSVO Fish from lakes in Western Switzerland: Assessment of the PFAS-results EFSA 2020: TWI 4.4 ng/kg bw per week, with bw = 60 kg Lake Geneva: 16 g fish/week Lake Neuchtel: 24 g fish/week Further data from Switzerland (Lake Geneva): 2007/2008: n=19, PFOS 100 % pos (7-94 g/kg) Ortelli et al. (2009) 2011: n=17, PFOS 76 % pos (16-74 g/kg) Bugey et al. (2012) 2012: n=37, PFOS 86 % pos (11-140 g/kg) Edder et al. (2013) 2018: n=14, PFOS 100 % pos (2.4-19.3 g/kg), PFDA 100 % pos (0.1-1.3 g/kg), PFUnA 100 % pos (0.03-0.6 g/kg) Valsecchi et al. (2020) 21FIPF Per- and polyfluorinated substances in fish - preliminary results Alexandra Jaus 11 Federal Department of Home Affairs FDHA Federal Food Safety and Veterinary Office FSVO Fish from lakes in Western Switzerland: Total PFOS concentration versus Species Hecht Felchen Rotauge Seesaibling 21FIPF Per- and polyfluorinated substances in fish - preliminary results Alexandra Jaus Flussbarsch Egli 12 Federal Department of Home Affairs FDHA Federal Food Safety and Veterinary Office FSVO Fish from lakes in Western Switzerland: Total PFOS concentration in Coregonus sp. 21FIPF Per- and polyfluorinated substances in fish - preliminary results Alexandra Jaus 13 Federal Department of Home Affairs FDHA Federal Food Safety and Veterinary Office FSVO Fish muscle samples from Lake Sils in Graubnden 10 x Salvelinus umbla, 10 x Salmo trutta, 10 x Thymallus thymallus PFAS concentrations were approximately in the range published for other alpine lakes Graubnden will inform on detailed results in January 2022 21FIPF Per- and polyfluorinated substances in fish - preliminary results Alexandra Jaus 14 Federal Department of Home Affairs FDHA Federal Food Safety and Veterinary Office FSVO 21FIPF Per- and polyfluorinated substances in fish - preliminary results Alexandra Jaus 15