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E . I. d u P o n t d e N e m o u r s & C o m p a n y
IN C O R PO R A T ED
W i l m i n g t o n . D e l a w a r e 19898
POLYM ER PRODUCTS DEPARTMENT
ex perim en ta l station
PERSONAL AND CONFIDENTIAL
cc: A. J. Dahl - 353 B. W. Karrh - NIIUOO L. J. Papa - 269 Pral File I.C.
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November 3 , 1981
TO: DR. Y. L. POWER - PPD, Parkersburg FROM: S. S. STAFFORD
ANALYSIS OF BLOOD SAMPLES FOR PERFLUOROOCTANOATE (Job No. 810-578; PRAL Nos. 81-^871-^9 1 2 ; Notebook Nos. E22?!1*,E26238,27^3 2 )
As requested in your letter of 10 /20/81 to L. J. Papa, the 12 blood samples submitted then have been analyzed for perfluorooctanoate (Cg) by the usual gas chromatographic method ES-567. Results and sample identification are given ir. the attached table.
Attachment jah
Key Words: Perfluorooctanoate GC Blood Analysis
There's a world ol Ihings we re doing something about
000159
EXP000066
EID713880
TABLE I CONCENTRATION OF PERFLUOKOOCTANOATE IK BLOOD (a)
Sample PRAL Mo. Date Sampled
81-1*371 81-1*872 81-1*873 81-1*87^ 3 1 -1*875 81-1*876
81-1*877
81-1*875
10/6/81 10/7/81 1 0 /7/81 10/7/81 1 0 /7/61 10/7/81 10/7/81 10/7/81
8 1 -1*879 8l-l*880
81-U881 81- 1*882
81-U883 31-1*881* 81-1*885 81-1*886 61-1*387 61-1+988 81-I+889 81-1*890
10/8/81 10/8/81 10/9/81 10/9/81 10/9/81 10/9/81 10/12/81 1 0 /12/ 31 10/12/81 10/12/81 10/13/81 10/13/81
81-1*891 81-1*892 81-1*893 8i_i;89l* 31-1895 8I-I896 8i-l*897 8I-U898
10/13/81 10/13/81 10/13/81 10/13/81 1 0 /13/81 10/13/81 10/13/81 10/11/81
81-1*899 81- 1*900
31-1*901 81-1*902 81-1*903
10/1W81 10/11/81 10/11/81 1 0 /15/31 10/15/61
P.R.No
1952 1*720 1*75** 1733 1*755 1*756 3578 W.S. 953 3519 1*538 ltll+6 1*360 1*351* 3753 W.S. 1*058 W.S. W.S.
1*611 1730 1663 1109 W.S.
IW.S.
1825 I 1760 1 1613 1 1978 1 1530 1 1675 1 1231 1 1290 1
Name
GC Analysis Date Analyzed [Cr ], Ur F*
10/23 & 10/28/81 0 .1*5
10/26/81
0.039
10/26/81
0.021
10/23/81
0.06l
10/23/81
0.0073
10 /23/81
<0 .0 0 7
10/28/81
0.78
1 0 /23/81
0 .3 0
10/23/81
11.
10/23/81
0 .1 9
10/28/81
1.2
10/28/81 1 0 /2 3/ 81
1 .3 0.32
10/28/81
0.1*1
10/26/81
0.18
10/27/81
1.5
10/28/81
0.27
10/26/81
0.11
10/27/81
2.8
10/26/81
0 .0 1 3
10/26 & 10/28/81 0.010
10/27/81 10/27 & 10/29/81
0 .0 3 9 0 .1 7
10/27/81
0.1*1*
10/27 & 10/29/Sl 0.26
10/27/81
n .d .
10/27/81
0.015
10/27/81 1 0 /27/81 10/27/81
0.8" *.5 0.76
10/27/61
1.1*
1 0 /27/61 10/27/81
0 .7 5 0.030
0 >)
*REDACTED*
000160
EXP000067
EID713881
TABLE I CONCENTRATION OF PERFUJOROOCTANOATE IN BLOOD (a)
Sample PRAL No. Date Sampled
81-L90U
10/15/81
81-1+905 81-1+906 81-1+907 8l->+908 81-I4909
10/15/81 10/15/81 10/15/81 10/16/81 10/16/81
81-1+910 31-1+911 81-I+912
10/19/81 10/19/81 10/19/81
P.R.No.
3520
1+226 1+568
1697 11+1+7
w.s. w.s.
596
w.s.
Name
GC Analysis Date Analyzed
1 10/29/81 10 /28/81 1 10/29/81 1 10/28/81 1 10/29/81 1 10/28/81 1 10/28/81 1 10/29/81 1 10/29/81
[Cr ], vr F 3 .6 0 .0 1 0 0.71 0.15 0 .1+3 0.16 0.15 0.069 0.65
<b
(a) Analysis as described in Lab Method ES-56 7 ("Determination of Perfluorooctanoic Acid in Blood, Gas Chromatographic Method"* S. Stafford, 4/3/81-)-, using the packed column GC analysis with perfluoro-n-octanoic acid as calibration standard.
(b) Although the analysis is specifically for perfluorooctanoate (acid or salts), concentrations are given in ppm fluorine for comparison with the results of total organic fluorine analyses. (ppm F = 0 .6 8 8 x ppm perfluorooctanoic acid) Estimated uncertainty is + 10% relative standard deviation. The lower limit for quantitation is 0 .0 0 7 pgF/g. The detection limit is 'V 0 .0 0 4 pgF/g, but concentrations in that range cannot be well quantitated and are reported as < 0 .0 0 7 . None detected (n.d.) is reported for samples with [Cg ] < 0 .0 0 4 ppm. which cannot be distinguished from reagent background.
O O O ib l
REDACTED*
EXP000068
EID713882
