Document gE3V8aRKKzwJeQE50pXBXrV7V

FILE NAME: Chemical Abstracts (CHAB) DATE: 1942 DOC#: CHAB023 DOCUMENT DESCRIPTION: Abstract Originally Published in 1941 by Nordmann 3 Co ' 2 . ^ ^ 1942 2005 11G--Pathology 2006 many diseased states it remains substantially the same ' hemolysins) under the influence of Cl were investigated. as in normal serum. L. E. G. Therapeutic doses of Cl were used for the expts. (1: Chemiluminescence of alcaptonuric urines. Lynn D. 200,000). Chlorine-treated rabbits immunized with anti Abbott, Jr. Proc. Soc. Exptl. Biol. Med. 49, 14-15 diphtheria toxin produced a higher titer of agglutinins and (1942).--Alcaptonuric urines, as well as soins, of hon.o- preeipitins than did the control rabbits; in rabbits im gentisic acid and Pb homogentisate, give off light when munized with sheep erythrocytes considerably smaller made alk. with NaOH and shaken with air. L. E. G. differences between the control and chlorine-treated ani Intravenous administration of bovine serum albumin as mals wereobtained. Chlorine treatment had no appreciable a blood substitute in experimental secondary shock. . effect on the production of hemolysins. The absence of Harry A. Davis and A. G. Eaton. Proc. Soc. Exptl. any changes in the titer of the hemolysins during chlorine Biol. Med. 49, 20-2(1942).--Bovine scrum and plasma treatment indicates the probable existence of a different and bovine serum globulin arc very toxic when injected reactivity of individual physiol, systems of an organism intravenously into dogs. The toxicity of the whole crutn or to the same action. The immunobiol. stability of guinea plasma seems to be due to the globulin or one of its related pigs against diphtheria toxin under the influence of chlorine fractions. Bovine serum albumin is harmless when in changed very little during immunization with anatoxin and jected and is effective in raising and maintaining the blood without immunization. - Fourteen references. pressure of dogs after severe hemorrhage. L. E. G. W. R . Henn Effect of renal and systemic bloods from normotensive 3 The content of bromine in blood during the various and renal hypertensive dogs on arterial rings. M. R. Salk phases of tuberculosis in children. E. M. Mondini and G. E. Wakerlin. Proc. Soc. Exptl. Biol. Med. 49, Pediatria (Riv.) 48, No. 5, 320-31(1940).--The blood 22-4(1942).--The vasoconstricting effects of heparinized content of bromine was found to be normal in the initial renal vein and femoral artery bloods from 3 dogs before stages of bone and pulmonary tuberculosis. However, in and after production of renal (Goldblatt) hypertension tuberculosis of the large serous, pleural and peritoneal were studied on arterial segments from mesenteric arteries membranes the amt. of Br is always high when the process of beeves. No significant differences were found. is of an exudative type. It is normal in the active type. L. E. Gilson To judge from the detn. of excess of Br in exudative tuber Changes in antitryptic power of the blood associated with * culosis of the pleura and peritoneum it is believed that anaphylaxis in guinea pigs. Kenneth L. Burdon. Proc. concomitant disturbances are related to the chlorine metab Soc. Exptl. Biol. Med. 49, 24-7(1942).--Preliminary. olism. R. P. E. Hopf L. E. Gilson Lung cancer due to asbestos dust in animal experi Encephalitis virus antibody in serums of experimentally ments. Martin Nordmaun and Adolf Sorge. Z. Krebs infected animals by agglutination of virus-coated cells. forsch. 51, 108-82(1941)--When 100 white mice were E. C. Roberts and L. R. Jones. Proc. Soc. Exptl. Biol. exposed to asbestos dust for a total of 07-80 hrs. over a Med. 49, 52-4(1942); cf. C. A . 35, 4831, 5177'.--Pre 0-week period or for a total of 72 hrs. over a 13-week per liminary. L. E. Gilson 5 iod,Gl survived for examn.20 weeks later. Of these 01,20% Experimental necrotizing arteritis. II. Mercuric chlo showed a keratinized multicentric squamous epithelial lung ride as effective as uranium nitrate in its production. Rus- carcinoma and 42-57% showed epithelial lung neoplasms scll L. Holman and Willard C. Hewitt. Proc. Soc. Exptl. in all stages. This finding supports the authors' view that Biol. Med. 49, 58-02(1942); cf. C. A . 35, 8089.--HgCIj asbestos dust may cause primary lung carcinoma in work produced the same effects as U nitrate when used as pre ers. Marion Horn viously described. L. E. Gilson Observations on the blood of rats with implanted Jensen Experimental atherosclerosis and soybean lecithin. sarcoma. Hans v. Euler and Inga Pettersson. Z. Krebs- Homer D. Kesten and Ruth Silbowitz. Proc. Soc. Exptl. Jorsch. 51, 193-8(1941).--The abnormally high pyruvic Biol. Med. 49, 71-3(1942).--Feeding soybean lecithin to 6 acid content of the blood of rats with implanted Jensen rabbits receiving cholesterol restricts hypercholesterolemia sarcoma (av. 50 y/cc. as contrasted with the normal and diminishes arteriosclerosis. L. E. Gilson 12 y/cc.) is considerably reduced (to 20 y/cc.) within a Electrophoretic identification of antibody to tuberculin few hrs. after injection of 1 mg. nicotinamide. The protein. Florence B. Seibert and J. Walter Nelson. pyruvic acid content, however, does not drop com Proc. Soc. Exptl. Biol. Med. 49, 77-80(1942).--Antibody pletely to normal even if as much as 4 mg. nicotinamide is to tuberculin protein was identified in serum as a compo given. An action similar to that of nicotinamide is ex nent with an electrophoretic motility close to -globulin. hibited by cozymase, insulin and adenosinetriphosphorie This component increases in serums following sensitization 7 acid. Marion Horn to the protein, and is removed in part with the specific Cleavage of d-Ieucylglycine by serums, blood and organ ppt. produced by adding antigen to the immune serum. extracts. I. Hans v. Euler, L. Ahlslrom, B. Hogberg _ _ L. E. Gilson and Ann Marie Lilja. Z. Krebsforsch. 51, 248-72(1941). Characterization of milk influence in spontaneous mam --Ability to cleave d-leucylglycine appears more often in mary carcinoma [in mice], Maurice B. Visscher, Robert the serum of cancer patients than in that of normal human G. Green, John J. Bittner, Zelda B. Ball and Heinz A. subjects, but the difference is not sharp enough for use in Sicdentopf. Proc. Soc. Exptl. Biol. Med. 49, 94-0(1942); diagnosis of cancer. Serum of rabbits with metastatic cf. C. A . 36, ISO5.--Preliminary. The active carcinogenic Brown-Pearce carcinoma showed regular ability to cleave agent or agents in the lactaling breast from high-cancer 8 d-lcucylglycine. In the scrum of a rabbit refractory to mice appear to be coned, in a fraction obtained by ultra transplantation of Brown-Pearce carcinoma, ultraviolet centrifugation of homogenized tissue. This fraction is vir irradiation elicited ability to cleave d-leucylglycine. tually free of matter above colloidal dimensions and Marion Horn contains a large share of the sol. material of high mol. wt. Complement fixation in rickettsial diseases. Ida A. L. E. Gilson Bengtson and Norman H. Topping. Am. J. Pub. Health Pancreatic calculi. Mangaldas J. Shah. Indian Med. 32, 48-5S(1942); cf. C. A . 35, 75171.--The complement- Caz. 76, 516-19(1941).'--A clinical report is given of 2 fixation test tor endemic typhus is of value in the detection cases. There were no symptoms typical of this disease ,, of active or past infection. Titers of 1:128 and 1:250 alone, except the radiological findings. Glucosuria and 9 may be reached on the 9th or 10th day of illness and hypcrgluccmia were present as well as increased and un 1:4,090 and 1:8,192 on the 14th or 15th day. The com digested fat in the stools. Helen Lee Gruchl plement-fixation reaction is a better criterion of past in The effect of chlorination on the production of immunity fection with endemic typhus than is the Weil-Felix test and the immunobiological stability of the organism. G. A. as complement-fixing antibodies may be present in signifi Ionkin and M. N. Khanin. Vcslnik Mikrobiol. Epidemiol. cant dilns. up to 5 or more years after the illness. The Parazitol. 18, No. 3-4, 254-f.5(in French, 2G5) ( 1939).-- complement-fixation test may probably be used to differ The method of sp. immunization of an organism and the entiate between endemic typhus and Rocky Mountain production of immune bodies (agglutinins, preeipitins, spotted fevers. Spotter! fever serums tested against a