Document gE2ogg0yZa6aRJqogNxXn0N39

Company Sanitized. Does not contain Tsoa cri, AR226-2847 -- **'*" 'icuiuui a a n a company Haskell Laboratory for Toxicology and Industrial Medicine * ^ acute oral test Results: Dose (mg/kg) 25,000* 17,000 11,000 7,500 5,000 Dose in mit 5.8 4.1 2.5 1.8 1.2 Summary: _______ m ate L e th ^ ^ o s ? Mortality** D - Id. D - Id. D - 4 d. S - 14 d. S - 14 d. Clinical Siens Lethal Doses; Piloerection, diarrhea, labored breathing, prostration, wet perineal area, weight loss and lethargy! jjfonlethal Doses; Diarrhea 1-3 days after dosing, lethargy on 3rd day after dosing and congestion 6-14 days after dosing at 7500 mg/kg. Piloerection on 6th day after dosing at 7500 and 5000 mg/kg. Weight loss for 1 day after dosing at 5000 mg/kg and sporatically from 1-14 days at 7500 mg/kg. ALD 11,000 mg/kg *d"lt O * - TM C in single doses; tt. Approxi- + Specific Gravity = 1,080 * Administered as a divided dose l** ? " S d * = Found dead < ) days after dosing. ( ) d. - Sacrificed ( ) days after dosing. Report No. 723-75 CVF/ldp Date Issued: December 9, 1975 Report by: Approved by: Company Sanitized. Does not contain TSCA CBI Charles V. Frazifer" Research Toxicologist r0\ C_ V v jJ c A Michael Kaplan Chief Oral Toxicology Section