Document gD3O5qEb75DO5pYe6mGKw941N

lSC't**3T*5Cr ham in ii'Niiimil'*! uml the nimplclt'il relmsed ntfriehcd he t)i<- -lu-uyl.-ilivnyl tlVXA simply fry Marvin-.; (*rjin llj*- rii.o~.j:i.e.iitN'A :>ni|>li'x Jo ubi.di it. is hound for tlireoiiMi.1. tViiIi this ho has luvn iihii' to dtiiiv the fry lint <l:.V,\ iM.bttifc '`iirrvi-.ijj l.hc b-l nn.inu.aei.l cimdirimis ncivsKiry for teniiimiinm; ineiiii.aiiig the (liiorjiitrai-il, There. must. he n mrrlinniMU lor rvndii) complex under suitable conditions with or will: Uierhain (ttvi.in.iling codmi Jtfrmictiihin-i l.'AA, UAO, threonine or supcriintaiit citzynn** showed Hint to tret- iiiid U(/A'end to.|i- for chain termination) tun! i-lmviii" rcleiov it is-uocci .-ary Imt. not suflicionl to complete t lie llie Just jii j.Ji lvl.MJXA build. in liiurkini ft/ajihy*. peptide fry inenrj-orating tliivonino anil that release /.`ts. Com'.,S&. 77J fIhe describe* an exporiiiirntul is not solely dependent on the transfer cn:,\ im-s syshun devised to givu n rapid assay for chain termina required to move the ribowmn* from the thmmyl rtsl.iu tion, and in (ift Xtil. Arw/. fief., 53, Ifril (HKiV) Id tlitt UACJ terminatin'.: etiilon. Release does,however, lu- reports I he dimimy of an enzyme* required for depend upon (lie presence of a supernatant factor. Thir. tcrininalion. - factor, with a imtecuhir weight of hrtnocii -tO.Wu and The oss-ny for termimtliori employs tin* HXA from 5(1,000, Pediments bet ween 3-&S and 4`5-V. Recanre it-' an umber ir.ufrtnl. of the coat protein "one of the KXA . j'eleasiug nativity is not afljrctccl by RXaw, it cannot bae.toriophuge Itn. Tliid ivuiUmt has an amber codon, he n't RXA-protcin complex. Apparently the substrate' UACJ, at I Ii*' position of the sixth airiino-ncid, a gluta .of the release enzyme is the riW'ome-:HX.Vpep!idyl mine residue. in llie 7/17 coat profyin. molecule, Jn n iliXA complex so that it must act directly at tlm rii.o- coll free.system the mutant Ha A directs tin- synthesis some and not cleave the /RXA from peptidyl-JJlXA of a .snail X-lmuhtal peptide of the coat protein with . already released into the supernatant, which was the the ccqucmv N-fonnyIirc!l.u!a-(T-aspii-phc-thr: the other possibility. . ncxt.aiinnii-.nid in the coat protein is "Infr'induo, hot Capccdii docs not yet-know whether the release wiili the mutant RXA tlie amber codon caucus pre enzyme works clone or in conjunction with or her faelore. mature tunain.v.itci of r-ynt Ju ris end the releaxe of the in particular a liypotludioal chain termination /HX.V hexapcptiiJe. The great virtue of tliis system is that which reads the tVriiiiiiatinn codon but iIobs not tarry till' unh.-rminutnl peptide still attached to the jiej>tidv.'- an amiho-arid. Many people, including Gnpcrchi, have /HNA can he distinguished from the terminated peptide searched in vain for such u fllXA species, and although released fmin Die /KXA nnd the amounts of each .negative results can never exclude the possibility that measured. Furthermore, starving the system for any one Midi /HXA exists it is reasonable ii> think about of the six niuino-tieids in the peptide arrests the trans nllcrnativb models in which tho terminating codons lation mnehinwy before it reaches the UA(5 rodon so are' read either by the ribosome or the release enzyme terminal ion can ho controlled, .. or iit which nonsense cr,dun* function-simply because Kxploitinx. this procedure, Capecchi isolated a Ihcy cannot be rend at. all. Further cbnriiderization complex of ribosome, willXA and pentapeptide of the release enzyme could -well decide the issue. Chlorinated Hydrocarbons in British Wifdiifie by 0. C. HOLKFS ' J. H. S/MNONS 1 J. O'G. TATTCN ' Lr.boritory of th* Government CFemitt. Lontfcn Pdychlorobiphcnyl compounds have been detected In Bricish wildlife. In birds' livers and eg^s they are often in greater quantities than organochforino pesticide residues. Polyehlornbiphonyls arc known to be toxic, and their detection in wn'diifc raises the question of the adverse effect they may have, U'wux Mild bin!/ epgs- nr tli- livcrr of I'.ritfrll wildlife aw* cliloriiui in iiiktuu', with u taili-tuidiftl. clilviioc roi:teii>. 'xumiiii'd by f'.i<-liijiiid tliionyilngropliy (til-t.'l using mid coiisi<|Hi'iilly possoau I'ltctivin-ciiptiiiiiig prop(.`Mies. ili'Ction-cnpiine (li'i.-rlinii, jvnkn (riv>,pi-.udii,g to Kiu-it On bitiironc or 'Ajikvot/ OJ.t* e,iluiu>is. tin- acri'-s of OlVunovltSmitn1 p.'sf ir-iilrs irs JSH C, litl-lrlI ill nmi Ul VJ\ /jud pisiks for tbcsi1 compoiu.iN uonnally ik-giusnt tlicjMint thfir n)c|j)t>i.lji,.s iiml litviikih.uii piiMlucts. /.fi..|| at wliiuli /yi'-TDr: and />*' 1)1 IT nro cniiepiij; from tin- n tlw ri>4nU,iii( cl:.-nniiUogmiiK. 'I'ln-w p.-i>)<b Mii.n'i iint-s ciilimms mirl exiciids, in l.-i'iAs uf ivti nti-.in times, to four lypo-ta'iit n;um:iis ttiiicli lire rigiiitfcoiit iron) a tnxictilo- , or live 'tinvs that- of /#//] )DT, which is t lit* last of tls> t'inil pfiint of \i-w, but. tli.. Ki-u-i'ivitv of itunloin imk!ru- commonly sicotining jiesi ieitlcs to emerge.' 'ms nisei i-ii.il.le, i-i.ni]di-ttly fu.-denificiiiil amoimts to lx* Ueforo cxamin.il.ion fry <JLC`, wimples Jmve nainvitly dnti-CN*d. Analysts cnuc.'iIi.'d v.il!i th (Ictr-niliiMlioii of frecn tiibjcct-d to a fitiily rigorous chun-nri j'rnCi.diir.`. i.rgi.iiocliltiiitiv ]>-.(ii;idi'< in v.iMlilV, limvew-r, Iirw king micb n>- Hint ofrfi' l,Viiifr,,it ^i"junder rt/if.!, wfiieh iuHml. liei-i, flivaic tli i) it is run imu/ii-il for nn iidditim.id ru<ii< s n dinn.'tliyir.niii.'miiilo-Jii'xmic iMiiitiun nod jii'.ig.- <`f ns many os leu pi'ul;-, eiirr,..pi.ridiiic tn liiiirfr.-iitf/it-d thiougli n column of prepared ftluiniml. Itisous.* tlirv.. `..nijHMiiiils. id-i to upjM-iir on rlu.* tfntMiiiitogniniN1'4. uiihnmvn con.)ioiit;(U nio similar itt iMtnro ainl pr.|'.-ni.>, J.iMli- is litii.wn .f tin1 Kmir.l.iri- r.i.it orifj's *f tln-sr c>m- to il.ii orgm.i,Jdiirinc p-.sliriiles, they nfro pus through l>uu(Isr b.|t l'.iil.ii:,iil |.,lb]i,ln.d that they wre orgu/m lliix mid Minit5';.>,*k'n*i-tip pintcditre*; conrcipirutSy, they MON-MT-003220 LEXOLDMONOOOQ78 VM* nV5w4rE. VOL. a 16. OCTOBER 21 TSS7 often inl'-flerc seriously with dotermimilinuii if ^/-TDK dint in wildlife ta'Causo of UVOfll>li>ill(J of the chlVIH.-lf-ORrapliio peak*. Suitable pniocdiircs have fovn devin-d to ovufi*ii.i> Ibis iliftiuu'ly of inluiTuritig |*.-uks. Otic ini'llmii is in effect. a bolter icsoluli<m of the.a* puii'-uhii- peaks l,v dinirc of a nuitablu ulut ionary filui::o for (MX.*. Another inoUiod, which til.-- deiiionsuatct, ihn jircfVnco of thcsu euinjmund-i in the sample, is the uro b of n pritlimitiiny thin-layer cliroiniitoa.-uphict iroaluiout.'. 'J'iic clc.iii'd--tip ext roots uro. oxfiinimfl mi silicn gel chromntoplairs using n 1 per e-mil Ktilulinii of iiciionii in hexami is mobile phase*. Spots corresponding to tho compounds etui then be found nt fir vuhios . between O S and 1-0, whereas llio ruin'- _ monly ocr vring organocliltirind i>vstirictoji ' nnd tiicir mvlidmliies produce spots of lower IIr values. A similar .'cpami ion can also bo shown with ivviiisn pharo paper chromuto- grophy* whereby the uiil-nmm compounds mow only a very short distance fiom tho linRB line compared with the pesticides ami their iiv.'iiiWiies. (jf\s-lii|uid chromatography using dual clmtukl (i"tcciiuti systems with srpnatc clixiron-rapturo ntul finme-ioiiiiuttimi ilctcc- tori lias ;d.-o hcen used to dcmonstinln tho presence of largo ntnyuiits of wo-.vkly clut-lron* capturing inateriul, in udditiou to known peslicido I'-sidm-s, in (dm eggs of oyster Catchers llliicn.diopvs Oilniivjii*)*. Experience in this hi)"'i.ilory has shown (hat tin-,a. (..inpeund;' occur irmst frequently nnd in llie Iniui'sl. }iiii|'oi-ii.ms in the livers, fat ntid of biicls, ji.ir! i*'iidinIv* terrestrial 1 irrd.itnit- .-u'-h ns spamw)i-iwlis l.trripilcr lu'si/s) nii'.l h.-siret* I rj.rrr.-s :md marine livders ruvli ns k li!!el)lots [(Win Mid kiitiw.ihca {/.','iii-a trill. 40 they a!,.- cmniunuly occur in f:c-U\\v,tor fish. Vi'e iww (h-u-i'li'd small amt-unt* tisleiitisn tin: (cdn> in human ai.d animal fat sampler, but loss fre.-juciiily and in much t-inalhr proportions fik'. 1. C-Hau!d etirmn.MC'.TSt'.<rlniltitranj)lilIp'.VJR.rOnrIIKfilleos.tiet Uvtr kt>a |U * (cnuain-it! tlniii in nviiiii rumples. " v. A Mii'.ii'ir f..iics or rhrmniitogrtipliie peaks has been properties. In the proscribed extraction nr,d GLC condi nWrved by Holden'''." when examining cxtnwiiN of scab tions, the-ii mixtures pioduee a Kcries uf diioniukigrnphic null fish tnlicii in Scottish uaiera. lie found that (he pecks peaks of the Ij'js* in cjiu-.-tion. - given by iIn' extracts of fie.di nnil rca-wnfci- fish rcpic-tcn- Thu cen.puiiials occin i-iiig in I'lifish w ildlife corretpand (oil fuii-ly l..w cWL.-mln>1 inn -, but tImre given byexlrui-ts Jo tlm in".'e highly cbhiriliatcd biphenyl enUlpnaoch ratbei *>rsent blubber <''ini>|cimlcil to imu'll huger pnipiutinns. tbiVri~'he "indie bph(ly chbii-ituii'd lyy.s, 'j'lvrc bigl.ty of lim iialci' f.nmil by (liis hilmintory in birds' eggs. cbkwinatcd hijibenyls also m-cnr to Kne extent in (lie l)i'ii|ii|r c-*.i^i.!1nt 1 il.i cm ii.silv nlmnt I In-identity uf ilu-sv inmlogae.s palycldori'ieiplienyl pivp.u,iti<i!is which have -<im[ni'ieil>. Jilllu |i|iigii-sB has lieeu luado in idrltlifying commeieia! .* eimilai to tho-so of polycldoiobijihcnyl. them, lull tln-in li.is Inn;' I-n a penorul Mipposilinn timt It is pe>.-ildo i but a uf the compound , with very long limy Wi-ii! eilher furliar l.nvhdnuii nr condensation rc-tciitioa times ncnu'iiuz in rtrilisb wildlife uro lightly proibicis uf the mpanuchlnriiio pe*lieitlus or J'u.vibly clilonuatcd polycIJoroieiiibenyl eompoaiuls. ' ion.o coii.ii.einil.s nf tiicso wiili natural products such ns Pip. lo shows (In* yus-ljniiid eluuin itogram of hii protein lMuitcr. . extinct from :> ki-strel lin-r. The (N-ahs ei-rrcsiiondinj to Jim<on. liownvcr, suroecdetl in identifying a scries nf {'>13 ng), Ix'i.i-Mlli! (11-33 ngl nnd p.innn.i HfiL' siieU jK'ul;< us com-puiKliug to pnlyvMi>iolt;pl:.'jiy! com- (l)-03 ti") .iic labelled. Tito other peaks form tho rc-ii-m pmuids, in >:{i pile, tcl.en in ilitfcrent pail* of Sweden, rofoiTcd to above ui:d until now would hive boon regarded .and in on rnglo,}. Wc h.ivn now hern able to show ilmt eimply ns '`iinhnnn-n oiganorlihniiie cuiupomids not the long iN.iontion time cvmpimnds oeeurring in l.lrilish convsponding to imy known jiedieitlc or its metabolites". wildlifu m also pnlyeliku.,biphenyl compounds. Mr. 16 i l;ow> tho utiuIogoiiK ehrmnatogii.m of a eoiiimv- ^ilyclil.ii-inateil liijdi.-ny) lias la'cu in cummon cuimri'.'r. Cial polyyliliircil.ilpht-t`yl Ivlin. Sn far u* vet.Mil inn tin.ss cial use far ;.iiiic time as n iihv-uiciafT in puiuts, rosins nnd ore enuceriu il and nfau-ti from tin? i*osticMi`o peaks, thcri* plasties, '(i also has (lcetiic.il insula liny jiropcilies uml is oxnet. in iteJung for till Imt a few j\tks in the two ran ho n-<.! foe n jiiuu!a r of cither ptoti'tliva piiipoo. clironut . ' CN.mmcivia! )>vcpamtic:>s of this m.-iniial niv usually pr.-.ded ai-ci.idiitg to thu degrc..> of ebloiinatiun, but nil of thorn mu se.h.-tiintinlly ccv.eihc,- niixturcs of polyrhloro. biphenyl c...iup;iinuls il.nl eouhl lc exp-ctwi to I'escuih'.i. the ej'jj.iiioehhirinr jwv*i ieich-s in (licit cticiuicnl and physical Tim chroinatnTenms shown vein old.-iira-d by use of a silicoan pur.i (t.Hi-SU 62) column, hut. thisptveiso ur.r.i-. fpondence between the re(e;i(i(in times nf ihn pi>..]( for tho ui.kitown compriiiiii! i and tlwsc fruin tfio pnivelitornhiplviiyl ivsin )msalso hecii (IcnioustMt.i! on *A|iii-/cn I' MON-MT-003221 j V. 7 *NATU/<i-, VOU. 216. OCTOBER i.T 1067 .U 229 T*ifl 1. Muslim(KvBiUKirtrt>mr*iiiUsrdu**nf*.*-t ekt*tutwhfthsm**:riMivitWm`)irn 0is ron-ss'rt (luflilririw 1'IKH In which (Icy near u strang nvemhlanre ehentioally rant pliyeiwilly. fi-Mi Vi . t/ Kamo of the samples ofluYd.-iixiiniim-dm thislaboratory iiitiimii Kl. rat ' 1*7:1 VI t \>7* aillMJUH KM> i'Cll *2*3) 'Zbl *Ht> 2-07 <IK-Xti OOmliimu tl.K, l-St l-SI tin vau liavu tavuiml in cniitniii higher proportion!* ofpulyclilnni. biphiHiyt rumjHiimd* than urgauoi-ltloriue p;*ticide*. l-'w example, the punlis <>n tlm r.lirnmuivgnim for tlio kestrel 1*91 tMU I'W 2*S1 a*&4 a*rit if nrt Mfrt ;t o;> ' L-tf, . s-.'li sZ-'tui-.r- 8*11* 2-BU . 8-W liver shown in I-'ijt. I wore caliniaw-d to 1k< equivalent to about 12 lift of. ]iolyi'liliirotii|ihniiyl coinjuniml*. This an 4-CH M2 7M9 iro fW tra Mi *&9 0*ift 300 4-ffit ill %(U\ 4*ca t Vll must l>n emit l asted against the orgunocliloriiu' pe.-lieide residues listed above. Tli-tv total only about 0-S t.R of which 0-311 ng is U'tu-BHt.'. an isomer of BHC which is. *MI, Kcitrrf llvt-fcxtift't; p*>t>'cMototiipti*tiyl ruin. ' gottenilly regarded ns non-toxin to wildlife. Grout concern hit* often lieeii expressed by conservat ion- md cyitnodlieonn column*. Tlio actual retention thnns ista about tho effects nf pesticides on wildlife, particularly ivcorilrd for tlm punk* ok thr-no three type* or column nro 'birds. Tho identification of theso other org.tiioehlarino givnn in Table I. compounds in wildlife prompts enquiries as to tlu- pcuiblo li'urili'T confirmation ns to tho identity of these com* toxic effects they may bo having. That theso compounds pound* lias been. obtained by a study of their behaviour on thin-layer chroniatnpimes, uhunina unit silica god lib&orplioii ciihimns and rovers phase pnjior nhromoto- grmns. In Addition, these compounds have been shown, to rescmblu tho pclychiorohiphonyl compounds in tlieir chemical inertness. 'i'lnu i Imy nro not ca-dly roodified by simple cti'Miiicul reactions to pi educe readily identifiable fihifis in Hair retention times on GI.O ns cun Im done", for are toxio is generally agreed"'**: tho polycliiorobi- phenyls nro in fact regarded ns an industrial hazard and threshold limits for them in oir have been ndvised**. Wo thank tho Mature Conservancy for samples of w.ldlifu and Monsanto Chemicals Ltd. for samples of polychlorobiphenyl resin*. '' . Sereivcd October 3,1067. 1 instiltiro. In p//.J)I)T by hydrolysing it to p;>'-DDl or lo ItMiurii. J,, Ahi!hi>. 06, 4J (tt>55>. oldriu by oxidizing it to dn-ldrin. llrrisn:i, Jt. Jl.. J. Sri. Fnt .t9rir..I7.IOtltKO). A number of livers nml eggs talun from birds in tho I /.Vjitrf tjl'it (ic'rruMrtttCl.rmiil, 10 (HM Stationery Oftloc. Load'in, 1063). Britbh Mrs or their ro.ulol witters have boon examined * Wnlkcr, (*. It.. Ituuiitoa, O. A..Mid H-'inluoa, It. II,, J. Set, IVJ .{fn'e., is, in ti9n.). . in this Inlmratory with results similar lo those obtained dr Kaulicrt Miisadir, M. J., I'cin, K., Cn.ll>'. E. W,, naiMScnd, T.. W,, for thi< best ivl liver ivfrrrrd toenrlior. While t ho ident ifier Kotsrii, J,, nad `i*l.i.nfi/s. 1., M.nl/tl, *6, J6.> (lOtth linn f (huso rornpounih; in British wildlife may salvo the. mysu-tv oT the** pen hi- on CT.O chroinningriirhs, it raise.., * Siiamoui, J. It., und 'Xatlun. 3, <Cin>un!f.,7, HI <10GT>. ' Abbott, I). C.. K;-n. It.Uni Tln.injba, J., J. lit > Kvsbf, it., Anti-j.-:. sr.i' otioci. however, tiuny other tpu-Mions. Why. for example, tin , * Jirp'.rl of tin CV.rnr.iriii C'SimiV, idC (IIM Stationery OCrc, lowloai these ftni!|ioiitiihk Het>nt lo he nccMitmlut.-d. most frequent ly 1P66). nml in the Inrp-st J'lvp-.rlians, in vermin types of wild " Hnlilvn. A. V.. siiJ Marsdcn, K., J. Ptec. Imt. Srir. Purif., CM (lilCO). life Mirh .is I'lnls. mmU nr.d fish, iiud only m th most in very s-i.-'.dl piiipui-t'oiu. ii. ni.ni or hi* d<e,,. ^ieaninin'.ssiivh > UuWtn. a. v.. .t. Amt. A>*!..a.*:i:.>l..4S|i6), ' 6ei.-i.-n, S,, AVir tv'.. SJ, CIS II tin. V. Irrti.r. Iii";-.ii.h i'rI ,/ /.(t.ttfria! Stlrriil>. t'`J <KU- n (why r.r sli-ep? bi lids ro-p-'ct limy Mi nt to lii.Ver :-,ti -w.n a .urrw.'-ti 'v- v-is*., tiw-u n-.urlu.diy from ihe orgum-i-Liiti-iiio jtfiMifi.tes which seem to have invaded nearly .ill .ispecl * of our enviromnent tint! * l:ri n.ll.>1 ..Oi'-ni-i-.t31.mfiotri. u/liCIWBMti-.ii ft 'J l.r,<>.<M Limit 4} (Cosunittec or. TlircihrM Luhii Vitii*. lti**t). Quasi-ste!!ar Sources, Superoovae and Novae by p rnowijt; P, F. Bi'ivJYVNt Univnrnty of ManchMier Inttitute of Science anil Tcctmolo*y ' coni'^erifiS l^c opacity of a surface layer of a star, the author concludes that ijuasi-stultcr sources, stipernovac and novae r,*ay be different maalfestations of the same mechanism. ,. It is usually considered Unit, the outbursts of rtovue ntiil absorptions. It is hnown Hint t//cc>.tV,-f,.YfA*i Mi (ref. 1). Mtpi'rnbvuii nr.- fimd.i;tw-iit.iHy lifii?ivut processus, but I where iudocud omissions are included. Suppose, now, that. shall lien- jirnpnsn u rn' ihunisin wiiirl, c.in nceoimt- for fj is Coiiipiessvd or diluted wit.lmut rllniigiug I J.-- iotut both plienC'iu.-iiii, imd which tit. the ntinc- time can necouiiv wuitbcr* nf ions; that is, Af'is v.-trit-d under Conditions for citln-i' piohlciu* <'.mi'i-riii.d with |u.isi-ste!J;ir sonrees ' which nndntaiii coiotnuL 4n/f!Ai.'A`. so thm fiA'.V,- (tpuisma). Ill |utrtii-iil.ir, f suggest th.it those outburst* voustunt. Evidently t//S,SiA.l! tr.Sirti/A/.'. Thus nrt' liliely lo Im nm'snti>>[iiu (ns inth-i'il they r.ro ohserved compression of L increuscl its opacity, while dilation lo >m Ur (invito). lhx-.iU*o tho oiM-igy uleased during n reduces the opacity. ' mperniivii outliurst is cmnparnbl* with tho stellar rest Of Icoatvo, tho totnl numlrer of ion* will not remain, energy, tin niiis-itmpie pin luust cnuhl mean that the star const unt in practice, hi-catiio tho rccoinbiiuili'm rntc i* is acivler.itcd In icl.uivi<li vrloeity .in mder to co:t*rrvii pro;wrtiiiiiut In ,V,.V{. 'If tie* percentage of atnnw ini/cd momrii-.-nn. tlm* nff-nding n Doppler exjilmintiiin of tlm is liirge. tlio density (if tuikvur.i.-d nttutw. A', will il.ereforo htruu rod-shifts of tin-j:i-t - i-Mclhir sonn'es. bo pi-opoi-tioiml to ,V..V(, Tlii* nv-itiis tlml lie- ruiitrlm- t Ci'iinidi-r the opa-ity of n Inyi r, J.. m llio snrfiu-u of a tion to tin. op.iity inudo by bound-botuid null bi iu.il-frc ulnr. Let A/r be th" tliieliiicxs mul J! t he radius nf J.. i.tid tmtisitiniiK within ut.inuizi'xl atoms is obo pM(mt!i<iital to lot L rnutain phiMu., n(. h-mpontluie. T. with th-nrim S/XtAff. This off-'ct, reciiguizi-il to bn impnrtuiit for mul pod-.ite inn di,n-iti,,-i St mid Si respi-etiwly. /. will Kicli.tr puls.'ilion1-*, fut ther increases tho opacity nf It on ,bi> opiiq-te to ritiliiili'-n i,f wuveli-ngth >. provided th.it t is eomprr-iidnn. . nlmttt 1, tvlu-re 7 is ti.*- uptii-.til,ilepih of A major cou- Some coiiri-'juvmro of this vurinlile surface opaeity will Mil.iiii.Hi to 7 is -t/. the optic.,! thiehuess due to fri-e-li'i-e now Ijo nxnmiia-it. I'juter equilibrium eoitditi-<iu< tho * M0N-MT-003222 LEXOLDMONOOOO8O