Document g2ROE7dBgB1jK9o5m1Zyw9avL
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Copies Co;
AR226-2882
Material Tested
E,, I. du Pont de Nemonrs and Company Hasktill Laboratory for Toxicology and Industrial Medicine
Elkton Road, Newark., Delaware 19711
HASKELL'LABORATORY REPORT NO. 56-80
Haskell No.
13,1'97
Ocher Codes
Study Initiated/
Completed
8/21/79 -
8/27/79
Mate
Chemical Jackson
EYE IRRITATION TEST IN RABBITS
Procedure; One-tenth mllllliter of the undiluted test material, was placed Into the right conjunctlval
albino rabbits. After 20 seconds, 1 treated eye was washed with tap water for 1 minute. The treated
was not washed. Observ.aclons of the cornea, iris and conjunctiva were made with a hand-slit lamp at 1 2, 3 and 7 days; Fluor-i-strip stain and: a blomicroscope were used at examinations after the day of
Results;
Duse
O.i mi
Treatment
Not Washed
undiliiCfcd
teal- matelrial
Cornea
Small arf of slight opacity
1-3 day
None
Ocular Effec:ts
Iris
Redness;
Swelling: Discharge
Con
none none none
0.1 ml
Washed
undil ui;ed
teat. male rial
Localized area of slight opacity 1-4 hours. Small area of slight opacity 1-3 days.
None
Redness: Mild 1Swelling; Slight Discharge :None
cr'rnea i.ipycily with no conjunctiva or Irlticeffects.^AncyedosedMith^heconipoundand promptly was area or slight cornlia opacity and transient very mild conjunctivitis. Both eyes were normal within 7
Although only very mild tempoiary ocular effects occurred, good hygienic practice would be f-o flu of waler ^{r.nr any eye contact with this material.
JEH;jr& Date Issued;
February 5, 1980
Report No. 56-80
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Report by; Approved by:
| J o lii^L.^ i.
h n U^H^-__ EB. Techni
____ Henry cian
JB^JH rf. k^Guer^aUl_B _______
L. Kennedy Chief, Acute Investigations