Document g270QvODYYR5Rpkj72adeepMe

FILE NAME: Chevron (CHV) DATE: 1961 DOC#: CHV021 DOCUMENT DESCRIPTION: Proceedings - 13th International Congress Occupational Health Proceedings THIRTEENTH INTERNATIONAL CONGRESS ON OCCUPATIONAL HEALTH LIST OF DONORS 1003 The following corporations, governmental agencies, labor unions, professional societies, and individuals contributed to the financial support of the Congress: AFL/CIO The Alcoa Foundation AMF Foundation Addressograph-Multigraph Corporation AAlllliesg-ChehnaylmLeursdluMmanSutfeaecltCuroirnpgorCaotimonpany AAmmeerriiccaanFBorreakLeoSyhalotey CGormouppany American Can Company American Cast Iron Pipe Company American Cyanamid Company American Industrial Hygiene Association (Northern California Section) American Medical Association American Metal Climax Foundation, Inc. American Mutual Insurance Alliance American President Lines Ltd. American Telephone and Telegraph Company AAmrmecroicaSnteVelisCcoosrepoCroartipoonration AArtlmanotuirc aRnedfinCionmg pCaonmy pany J. T. Baker Chemical Company Bausch and Lomb Optical Company Baxter Laboratories, Inc. Bayuk Cigars, Inc. Bethlehem Steel Company Boeing Airplane Company BBruidstdolC-MomyeprsanCyompany Burlington Industries, Inc. Burroughs Wellcome and Company California Texas Oil Corporation Campbell Soup Company The Carrier Foundation, Inc. CCaartesorpn,illPairriTe,raScctootrt aCnodmCpaonmypany CCehlaamnepsieonCoPrappoerratainond oFfibAremeCroicmapany CChhaanseceMVaonuhgahtttaAnirBcarnafkt, Inc. The Chemstrand Corporation Chesapeake Corporation of Virginia Chrysler Corporation CCilteiveisteSeCrvoircpeorCaotmiopnany Colgate-Palmolive Company Columbian Carbon Company Consolidated Edison Company of New York, Inc. CCoonnttiinneennttaall OCailnCCoommppaannyy, Inc. Com Products Refining Company CCroorunsine-gHGinldasss CWoomrpkasny Crown Zellerbach Foundation CCuurmtims iPnusbElinshgiinneg CCoommppaannyy Deere and Company DDeotdrgoeitMEadnisuofnacCtuorminpganCyorporation Douglas Aircraft Company Dow Chemical Company E. I. Dupont de Nemours and Company Dupont, Mr. Irenee EEaassttmOahnioKGodaaskCComompapnayny EEnledcitcroicttSJtoorhangseonBaCttoerrpyorCaotimonpany Equitable Life Assurance Society of U.S. Esso Standard EEsthsoylRCesoeraprocrhataionnd Engineering Fairchild Camera and Instrument Company Fawcett-Dearing Printing Company Federal-Mogul-Bower Bearings, Inc. FFeeddeerraaltePdaDpeerpaBrotamrednCt oSmtopreasn,yI,nIcn. c. FFoiroedsto8cneDrTuigreRaensdearRcuhbLbearboCraotmorpiaens,y Inc. Ford Motor Company TGheneeGraalrrAetmCeroircpaonraTtiroannsportation Company GGeenneerraall ADynnilainmeicasnCdoFriplmoraCtioornporation GGeenneerraall EFoleocdtrsicCCoropmorpaatnioyn GGeenneerraall MMioltlos,rsInCc.orporation GGelonbeer-aUl nTiiorne, aInndcoRrpuobrbaetredCompany Goldman, Sachs and Company 1004 LIST OF DONORS TThhee GB.ooFd. yGeaorodTriirceh aCnodmRpuanbyber Company Gulf Oil Corporation Gulf Research and Development Company Harnischfeger Corporation HHaelzmle,toMnr.LaHbaorroaltdorDie.s,HI.nc. Hercules Powder Company, Inc. HHeinyed,enC.NHe,,wpMor.Dt .Chemical Corporation Hinman, Mr. John H. The Hoover Company Hoffman-La Roche, Incorporated GHeoop.eAN. aHtuorraml eGl aasnCdoCmopmanpyany Hughes Aircraft Company Humble Oil and Refining Company IInndlaunsdtriSatleeMl eCdoicmapl aAnsysociation IInntteerrnnaattiioonnaall BHuasrivneesstserMCacohminpeasnyCorporation InCteorrnpaotiroantiaolnMinerals and Chemicals International Resistance Company International Telephone and Telegraph Corporation Iranian Oil Consortium JJoohhnnss-oMn aannvdillJeohCnosropnoration JS.onCe.sJ&ohLnasuongh8lcinSoSnt,eeIlncC.orporation MMiilnees SLaafbetoyraAtoprpielisa,nIcnecs. Company Monsanto Chemical Company National Biscuit Company National Dairy Products Corporation National Institutes of Health, Public Health Service, Department of Health, Education and Welfare National Lead Company NNeewwpOorrtleNaneswsPuSbhliipcbSueilrdviinceg, &IncD.rydock Co. New York Life Insurance Company New York State Natural Gas Corporation TNhewe NYeowrkYSotarkteTSiomcieesty of Industrial Medicine The News, New York North American Aviation, Inc. Norton Company OOhliino MOialthCieosmonpanCyhemical Corporation OOwtisenEs-lCevoartnoirngCompany Owens-Illinois Glass Company Pan-American World Airways, Inc. Paramount Pictures Corporation Pennsylvania Railroad The Peoples Natural Gas Company PPeitptssbi-uCroglha CStoemelpCanoympany PPrroocvtiedrenatndLifGea&mbAlceciCdeonmtpIannsyurance Co. Kaiser Industries Corporation KKiemnnbeercloyt-tCClaorpkpCeroCrpoorrpaotrioantion Koppers Company, Incorporated LaSalle Steel Company LLeegTgoeu, rRn.eaTu.-,WMe.sDti.nghouse Company Lever Bros. Company Liberty Mutual Insurance Company Life Extension Examiners Eli Lilly and Company Thomas J. Lipton, Incorporated The Magnavox Company The Mead Corporation MMeeidgisc,aJl .SWoc.i,etMy .oDf.the State of New York Metropolitan Life Insurance Company RRaaydtihoeoCnorCpoomraptiaonny of America Republic Steel Corporation RReeyvnloonldsFoMunetdaalstioCno,mIpnacnoyrporated R. J. Reynolds Tobacco Company JRoihchnfiAel.dROoeilblCinogrspo&raStoionns Corporation Joseph E. Seagram & Sons, Inc. Shell Oil Company Simplex Wire and Cable Company Sinclair Refining Company ASo. cOon. ySmMiothbilCOoripl oCraotmiopnany SSpoenrorcyo GPyrroodsuccotpseCCoommppaannyy SSttaannddaarrdd OOiill CCoommppaannyy ((CInadliifaonrna)ia) LIST OF DONORS 1005 Standard Oil Company (New Jersey) and affiliates Standard Oil Company (Ohio) Standard Railway Equipment Company StaFnoduanrdda-Vtioancuum Oil Company Stauffer Corporation Studebaker Packard Corporation Sugar Beet Products Company SSuunnstOrailndCoCmoprpanoryation SSwylivfatnainadECleoctmripcanPyroducts, Inc. Tampax, Incorporated Tennessee Corporation Texas Company TTiedxeawsaItnesrtrOumil eCnotsm, pInacn.y The Michael Todd Estate Trans World Airways The Travelers Union Carbide Corporation Union Oil Company of California United Artists Corporation United States Atomic Energy Commission United States Rubber Company United States Steel Corporation United Steel Workers of America Universal Oil Products Company Upjohn Company VAW--International Executive Board WWeaisrhtionngtSotneeSlteCeol mCpoarnpyoration Western Electric Company, Inc. Westinghouse Electric Corporation Wilson, Mr. Charles E. Wilson & Toomer Fertilizer Company Wiremold Company Woodard Research Corporation Win. Wrigley, Jr. Company Union Bag-Camp Paper Company Zenith Radio Corporation THIRTEENTH CONGRESS ON July 25-29, i960 Copyright 1961 by the U. S. Executive Committee of the Thirteenth International Congress on Occupational Health ALL RIGHTS RESERVED Library of Congress Catalog Card Number: 58-32683 Public Health GIFT DESIGNED BY HARVEY SATENSTEIN MANUFACTURED IN THE UNITED STATES OF AMERICA BY BOOK CRAFTSMEN ASSOCIATES, INC., NEW YORK /AfCi AJbi b3s ' b (cD 'HP euaLb (! H> oo L i b r a r tj EXECUTIVE COMMITTEE Chairman .. .. . L. W ade, M.D. V ice-C hairm en...................L. G reenburg, M.D. S. E. Miller, M.D. Secretary-General . R. E. Eckardt, M.D. Treasurer.......................H. E. T ebrock, M.D. Executive Secretary ............ J. W . M uckell E. R. A ston, D.D.S. C. U. D e r n eh l , M.D. T. Ely, M.D. B. S. Fox J. L auer, M.D. H. L. M agnuson, M.D. H. B. N ach tig a ll, M.D. N. N elson, Ph.D. M. N . N ew q uist, M.D. L. T. R obertson, M.D. I. R. T abershaw , M.D. S. P. W agner, R.N. 340 10 REPORTS OF ORGANIZING COMMITTEES In addition, many others visited points of interest to them either before or after the Congress. When the debris had been cleared away and the hubbub had subsided by Saturday, July 30, the paid registrations figures for the Congress were as shown in the following tabulation. NUMBER OF REGISTRANTS -- BY COUNTRIES Country Total Afghanistan ........................................ 1 Algeria ................................................. 1 Argentina ........................................... 19 Australia ............................................. 3 Austria ................................................. 8 Bahrein ............................................... 1 Belgium ............................................... 2 Bolivia ................................................. 1 Brazil ................................................... 5 British Guiana .................................. 2 Canada ................................................. 54 Chile ..................................................... 4 Colombia ............................................. 9 Cuba ..................................................... 5 Czechoslovakia ................................... 1 Denmark ............................................. 4 Finland ............................................... 62 France ................................................. 39 Germany ............................................ 36 Greece ................................................. 1 India ..................................................... 5 Indonesia ............................................ 1 Iran ..................................................... 2 Ireland ................................................. 1 Israel ................................................... 2 Italy ..................................................... 21 Country Total Japan .................................................. 20 Luxembourg ...................................... 3 Mexico ................................................ 6 Morocco .............................................. 1 Netherlands ......................................... 16 Netherlands-Antilles ........................ 2 Northern Rhodesia .......................... 1 Norway .............................................. 13 Pakistan .............................................. 1 Peru .................................................... 4 Philippines ........................................ 5 Portugal .............................................. 5 Romania ............................................ 1 Spain .................................................. 5 Sweden ................................................ 29 Switzerland ........................................ 6 Thailand ............................................ 1 Trinidad ............................................ 2 Union of South Africa.................... 9 United Kingdom .............................. 94 United States ......................................1040 Uruguay ............................................ 2 U.S.S.R................................................... 1 Venezuela .......................................... 7 Yugoslavia .......................................... 4 Total ........................................... 1568 One hundred and ten people paid and registered but were unable, for one reason or another, to attend. Thus the total actually present, exclusive of wives or guests, was 1458. It is the impression of the Organizing Committee that the Congress was an overwhelming success. Certainly the number and quality of tho scientific papers delivered was outstanding. Dr. Irving Tabershaw and his whole Program Committee deserve a special note of thanks for the hard work entailed in bringing such an excellent program to the Congress. It is the hope of the Organizing Committee that all those who attended, especially those from foreign lands, not only learned much from their attendance at the Congress but found our land and our people friendly and hospitable. We hope that new friendships were made, new understand ings reached, and that the memories of the Thirteenth International Congress on Occupa tional Health will linger long. Speaking for all members of the Organizing Committee, it was a pleasure and privilege for us to plan the Congress and welcome all who attended. KIVILUOTO 311 ml of the buffer described in Appendix 1, and continue afisnailn wAapspheinngdixmu1s.t-Nboermpearllfyormfoerdblfoooudr stipmeceism, einnsstetahde of thrice as for urine specimens. APPENDIX 3-- COPROPORPHYRIN ESTIMATION tubTeo a5ddm0l.2fremshl ly3 pveoridecdenturhinyedroingena psteorpopxeidreedsotelust tgieonnt,ly,1 rmelleagselacpiraelssaucreet,icanadcidplaacned in3 amlligehthtperro.oSfhbaokxe overnight. Observe the red fluorescence under ultra violet light, and grade the specimen 0-4-+ + + by degree of fluorescence. APPENDIX 4-- HEMOGLOBIN DETERMINATION wiTthake0.40.0p5ermlcbenlotoda,mamndonmiuamke huypdrtoox9idem. isMveoalusumree a(EbEsoLrpt4i0o4n), oannda ccoonlovreirmt etthere, ruesaindginga tsotanhdemarodglfoilbtienr ppaerrceedntcaagleibrtaotiothnegrnaepahr.est even number from a pre APPENDIX 5-- PUNCTATE BASOPHIL COUNTS thiMckankeessa, ftixhinforblaoboodutsmoneaer moinnuatesliindemoefth0y.l8-1a.l0comhoml, a(1llogwmteothdyrlyeneanbdluset,a6ingfsoord3iu0msebciocnadrsboinnatSeelilnars10s0taminl daesieoanigzeredenwactoelro)r.. Wash in tap water until the slide is eyeUpsiiencge saet dtoarak 6-gmromunsdquacroen,dceonusnert thanedpuannctaEtehrcliecllhs ipnuntcetnatecocnesllescuartieveclafsiseilfdise.d (aAs lltahrogue,gmh eidniucmo,usnmtianlgl,, vtehrye cfienlelu, loarr psotlryucchturorem,e,thaicscodrdififnegrentotiathtieonsizies offotrhefuirntthrear rteoftearlenccoeunotn iasngiinvdeniv.)iduCalolsceasteh,eanedyenpoiercmealtloy oanl2y-mthme sbqoutharec,ouanntds cfiovuenttimthese oRn.Bd.Cif.feirnentthpisartssquoafret.heRespliedaet, tRo.Bg.Civ.e caoupnut nocftatfeivecosumnat llofon5e0s. laCrgaelcufliaetleds paunndctaatne per 1000 R.B.C. NONOCCUPATIONAL ASBESTOSIS R aimo Kiviluoto Roentgen Department of the Central Hospital of Northern Karelia Introduction InPtlheeuraaldvreaanccteidoncaissesveoryf tohfitsenpnoebusmerovceodniinosiassbpelsetousriasl. cfiobrrroesliastiohnas bbeteweneenalmploesutraallwcahyasngfeosunadn,d atnhde saevcelreiatyr oinfvtehsetigpautolmrso. nOabrysefrivbartoiosinsshoans tbheeenococbusrerervnecde boyf psleevuerraall coaflcpifliecuatriaoln cinalcaisfbiceasttioosnis ahsavea arlsooenbtgeeennomloagdice. sRigepnorotsr cboymtphleicaGtieornmaonf aasubthesotrossis(1)h.avIne easdpdeictiioalnlytobeaednvamnacdede wcahseicshofplaesuberastlosciasl,csifpieccaitaiolncahseass hbaeveen bteheen cphrieesfenfitneddinign b(2e)e.nEoxbcseeprtveidn aamsboensgtoswiso,rkpelresueraxlpocsaeldciftiocattailocnahnadsmailcsoa a(3s,b4e)stoosr (t5o).various dusts including a short exposure to onTohcecudpiaagtinoonsaisl oexf pponseuurme otcoondiuossti.s Oisnplyrimvearryilyfewbasreed pmoaryts boef pfnoeuunmdoicnontihoesesliwteirtahtouuret o(c6c,u7p,8a)t.ioInnal Nexoprothseurrne bKeaerneliaat,traFcitneldanbdy, tdheurhiniggh fienwcidpeanscte yoefacrsaseisntoefrepslteuhraasl rcoaelcnitfgiceantoiolongsichowpiicntgurae,ravthereyr csiumriiolaurs atondthchaatraocbtseerrisvteidc ianmponnegumthoecorneisoisdeesn.tsThoef caasceesrhtaaivne abreeean, manadinliyn fothuensde cpalseeusranlodipsreeavseioucsouhldistboeryeloifcitaedde. qTuahtee opcuclumpoantiaornys oorf othfe tphaetiepnattsiesnhtoswheaddnonounciflionrimcailty,syamndptothmes moafinpnpeaurt mreovceoanleiodsitsh.aAt thsetuydwy eoref gthroeuapreedalroduinstdribtwutoioannthoofpchaysel-s leixtet-earsnbaelstofsactmorinesso.ugAhstb.estEovsenconfrsotimtutead stohleelycomromenotn gbeenenolocgoincsipdoerinedt othfevimewos,t apsrboebstaobsleduestitolionghya.lation had tubPelrecuurlaolsisc, alocrifiecmatipoynemraesuusltuianlgly forcocmurs huenmiolattheorraallxy, manadrkiesd siptuleauteradl otnhictkheenivnisgcearanldpdleisuprala.ceImn emntosot fcatshees isnutlrtainthgorfraocmic dourgstanisnhiaslaotbiosenrvuesdu.aTllyheocccaulrcsifibcialtaitoenralrley aadnvdaniscemdosctasoefstencalsciituumateddeopnositthse apraerieftoaul npdleuinra.thIne Tlahteeraclalpcaiurtms odfeptohseitschteaskte, bvaasraiolluys afnodrmms--edlaiarsgteinaclolyn. fluent plaques, bizarre figures, or roundish spots. The Roentgenologic and Clinical Picture of Cases Observed in Northern Karelia bilIantertahlely aidnvatnhceedcecnatsreasl pcaalrctsiumof dtheepodsiitaspharraegmfo;unodn cahnedstown atlhlse, mesepdeciaiasltliynaalnstuerrfoalcaetse.raIlnlythbeutinaclsipoiednotrscaallsyes; tlhateercaallccihuemst dwepalol,sitmtoarkeesofptleanceoeniththeer olenft,thoer ainntetrhoe coenntrtahle parirgtshto. f Ptheericdairadpiharlagcmal,ciafpicpaatiroenntlyis msoormeeotifmteens preTshenet.calcium deposits are located on the parietal dpelepuorsai.tsIwn earesoebriseesrvoefd.15T0hecapseasrinetoalinlotecraltoiobnarhcaaslcbieuemn dtieomnso,nasntrdatietdhabsyalsdoiabgeneonstnicotepdneinumsoomtheoarauxtopesxieadmainnad spuarrgieictaall cloasceast.ioUnsionfgsoalittaarnygepnltaiqaul ersoemnatgyenbeboeabmse,rvtehde, tchheesset wpallalquoerstohwaavridngthethdeiiarphbraasgems .toInwaarddvatnhceedicnanseers the lack of soft tissue mass between the calcium deposit 312 MEDICAL PRACTICES aanpdpariennnte,ranchdesdtiawgnaollstdicuael ptoneuthmeotphaorriaextalexloamcaitnioantioins pasublemstoonsarmyinfeisb.rosis among residents around the two is Tsehledommanjoeeridtyed.of cases of pleural calcification de attSriobmuetiningvetshtiegactoalrcsifhicaavteionpoitnoteidnhoaulat titohne ddiaffmicaugltey ionf sscerriiebsedofa1b5o0vecasheasvtehebeoerndincalrinyiccahlelyst sroymenpttgoemnleesxsa.mIninaa voibeswervoefditsinpatrhieetalul nlgocaotrionth,efevwi,sciefraalnyp,lecuharange(2s,5b)e.inIgt tfiiobrnosbiys, Pc-oArraenspdonladtienrgal tporotjheectiaonntseprerivmeaalreyd oprulpmriomnaarryy slueenmgsapnodssivbilsecetrhalatpltehueraasbinestoreslaftiiboenrs tmo otvhee wpiathrietthael scteangte. Eovfenputlhmeonmaaryin apsabretstoosfisthienseocnalysesabhoaudt n1o4 spuebr ponlelyu,ra,asthpursevcioauussliyng prceaspeinlltaerdy bhyemtohrerhaaguetshoor.n Tthhies jective respiratory symptoms. The series mentioned above has been selected solely lhaegmenoorurhsagpelaqcouaeguwlahteicshansldowolrygacnailzceisfi,esf.orTmhinisg tahecooryl atoccootrhdeinrgfatcotortsh.eTrhoeenctognencendtiaragtnioonsisofwtihtheocuatserseaferroeunncde cinohualdlateixopnlaoinf stmheallcoquurasentiotfietsheofprfoibcreosussremsuinlteirnagl fdruosmt. tcwoommasubneesstohsasmainseysetinbeKenuuthsjearovnilyanwdayittso nceoingfhirbmoritnhge seeTmhse tcolinbiecaslligsihgtn,iftihcaencmeaojofritthye opflecuasreasl schaolcwifiincgationno roouetnsitdgeenthidsiaagrneoasihsa. dTphreevimouasjloyritlyiveodf th2e5rec.aAsecscolridviinngg colnintihcaisl proesinptiraartoeryneesdyemdp. toms. Further investigations ftoicutlhtestoe fcarcetdsi,t.anIny voethryerfeewtiolcoagseys waopurledviboeusveorcycudpiaf pleFuroraml craolceinfitcgaetnioonlogisicofpsooimnte soifgnvifiiecwan, cet.hiTs heenrdoeemnitc twiohnicahl leexnpdossusrleightto sauspbpeostrotstodutshte hraosenbtgeeenn doibasgenrovseids,. gdiefnficduilatg. nEosairslyis pinleutyraplicaclhacansgeesseaosny bthuet inansteormoelactearsaesl Tmheethoddiasg. nIonsitshehasspuastuymet onfo2t0bceaesnesconnofiarsmbeedstobsybootdhieesr cphlaeqstuewsalml amyaycasuimseuldaitfeficinulftiyltriantioinnste, rapnrdetalatirogne coaflcipfiueld awmeroeunftouonfd,anatnhdophasyblleistteosasfbiebsetrosinwaosnefoucnasde. inSmtahlel mvooltnaagrey cthecanhgneiqsubey hcaidningheirnefbiyltrabtieoness.pTechieallhyighreckoilmo- lfuronmg othfeavnicainuittoypsoifedthecaassebeasntods imninteh.e lung of a cow masebnedsteods.mIninecsheisnt Nrooernthtgeernn eKxaarmeliinaaatinodnsofofOwutoorkkuerms pouf Discussion Cbeopppaeirdmitnoesthloecatfeadct inthtahte seavmene aerxeatenastitveentiobnilamteurastl *,` pleural calcification does not have to be a sign of aroTuhned ttohteal twnuomabsebrestoofs cmasiensesofampoleuunrtasl tocalocvifeicrat8i0o0n, sdeuvsetreexppuolsmuroen.ary changes resulting from occupational acsasepsrewvaiosufsolyunrdepionrtaedmabsys tshuerveayutohfora.bTouhtis10n,u00m0baedruoltf REFERENCES ipnahtiaobniatalnetsxpaonsdurme atyo inascbluesdteoscadsuesst.wiItnh pthreevihoiustsoroyccouf 1. JKaocmobp,liGka.,tioanndenBodhelrig, LHu.n:geDniaesbresnttogseen.olFogoirstcschhern. pthietalmoafinNporatrhteronf cKasaerselieaxathmeinleadckaot fthoeccuCpeanttiroanlalHeoxs posure has, however, been apparent. Some of the 2. RMunltlgeer,nsHtr..:, 83b:5e1r5,sc1h9w55e.re Formen der Asbestose. Die Staublungenerkrankungen, Band 3, Wissen pcoatuilednthsahvaevehanpoptehnaedd;antyheidseaamheowcasthese hdauvset ipnrheasluamtioend Vscehralfatg!., DFoarrsmchstuandgt,sb1e9r5ic8h. te 66. Dietrich Steinkopff 3. Siegal, W.; Smith, A. R.; and Greenburg, L.: Study ItnhaNt othrethdeurnstKriasrienlgiaotnhethreoardosad(shimghigwhatysb)edroespnoont shibalvee. o19f43ta.lc miners and millers. Indust. Bull., 22:434, pcoauvresme,enimt.pWossiitbhloeuttomdeinceidraelowghicetheexramthiensaetiocanlscifiitcaitsi,onosf 4. eSxmpiothsu, rAe . tRo.:cePrlteauinralducastlsc.ificAamtio. nJ.resRuolteinntggefnroolm., adruestreosruigltiinnagtinfrgomfroimnhathlaetioasnbeosftoasntmhionpehsyollritef-raosmbesstuors 5. 6F7e:h3r7e5,, W19.5:2. ber doppelseitige Pleuraverkalkungen afascbeesdtoesp,owsihtsichofisotahevrerfyibcrooumsmdounstsm, insuecrahl aisn tNreomrtohlietren- Rinfonltggeensbter.r,uf5l5ic:1h6e,r 19S5t6a.ubeinwirkungen. Fortschr. aKbalere.lia. The first alternative seems to be more prob 6. Emiasnen, bLu.dT, .M; ,H; aWrriasn, tWa,. RB..; Ca.n; dDWusotlafn, ,BC. .S;.:SNteoand occupational berylliosis. Am. J. Indust. Hyg., 1 caIllnedocacttuepnattiioonnatloptnheeumabosceonncieosiosf spoumlme oanuatrhyorsfibhroasvies 7. 3G1o:2y8al2,,R1.94K9..: Pneumoconiosis in the non-industrial bfiecsaitdieosn th(2e, 5p)r;oomnintehnet oapthpeerarahnacned,ofa tchleeaprlecuorrarlelcaatilocin p30o:p7u9l,a1ti9o5n8. of Rajasthan. J. Indian Med. Ass., hfiabsrobsiesenanodbpselervueradl bceatlwciefiecnatitohne (9se).vIenritnycnoof cpcuulpmatoinoanrayl 8. gKeinvoilluoogtioc,siRgn.: ofPnleounr-aolcccuaplcaitfiiocnaatiloenndaesmiac arnotehnot- aoscbceusrtowsisithitoiustapanpyarernotentthgaetnoelxotegnicsaivlley cadlectieficctaatbiolen mpualy monary fibrosis. It seems possible that even very small 9. pBhoyhllliigte,-aHs.b;esJtaocsoisb., AGc.;taanrdadMiolu.,llesru,pHpl..: 1D9i4e, A19sb60e.s tose der Dngen. Georg Thieme Verlag, Stuttgart, amounts of asbestos fibers may cause pleural calcifica tions. 10. V19o6r0w. ald, A. J.; Durkan, T. M.; and Pratt, P. C.: Experimental studies of asbestosis. Arch. Indust. InAanntihmoaplhytellsittse bisritmtloeremsintieffratlhafinbesresrpheanvteinneotascbaeustsoesd. 11. HNyogro.,, 3:L1.,: 19O5n1. the histology of asbestosis. Acta pinulwmoornkaerrys efixbproossiesd(1to0),anbtuhtopfihbyrollsiitse-haassbebsetoesn doubssterv(1e1d, 12. PWaetgheolli,use,t Cm.i:crCohbaionlg.eSscianndth.,e23l:ubn%g,s1i9n461.26 cases of p12o)s.sibFluyrtphlearyesdtudbyiesasabreestonseeadsedantoetiorelovgeaicl ftahcetorpairnt a1s9b4e7s.tosis observed in Finland. Acta radiol., 25:139, 326 MEDICAL PRACTICES A REVIEW OF RECENT DEVELOPMENTS IN OCCUPATIONAL PULMONARY DISEASES OTHER THAN SILICOSIS L eo Noro, M.D. Finland tioAntalthHeeaTlwthelhftehldInitnernHaetlisoinnakli Cthornegeresyseaorsn aOgocc, utphae sFurbenjeccht mPreonfteisosnoerdMinarcthheantdit.lep,reaselanrtgeed aandrevcioemwporefhtehne sTivhee bOirbgliaongizrainpghyCobmeimngitteaettahcahsedat tothishistimperesaesnkteadtiomne. stoevperraelseynetaras. rIetvimewustofatthoencseambee ssauibdjetchtaftrothme tchoemlpaislt einasgy otfassku.chMoarebitbhlaiongreavpehricberfeovriee,wrehsaesarcnhot wboerekn haans bperoebnlefmocuhseads obneeonccduispcautsiosendal aptulnmatoionnarayl dainsdeasienst.eTrnhae taigoonailn mMeeiltainng. sF, rtohme ltahset ltiimteeratbueriengwhoniclhy htwaso bmeeonnthast rmeycednitspyoesaarsl, dIeahlaivneg fwoiutnhdthailsmsousbtje3c1t6, aarntdiclyeest fIrocmannthoet lhiashveedhaind athcceesws otrolda.llI thshealalrtficolleloswf,rowmiththissomfieeldexpcuebp tioTnsh,erMe airschreaansdo'sn ctloasssitfaitceatiaotn.the onset that the con sbteacnotmiendmusotrriealiaznindg misorceauspionlglutthede. aiGrrewaet bmreaasstehse otof cpoeuonptlrei,ese,veanrethechpaenogpilnegs otfhethire bsorecaatlhleindglesasi-rdetvherlooupgehd Ithaemir mheorveemtheinntkifnrogmspaegcriifcicualltluyraalbotoutintdhuesthriuagleceinndteurss. tarniadliCzahtiinoan. Bpruotcemssanr'sigbhrteantohwingtaokrignagns,plaancde eisnpeIcniadlilya fhliusenlucensgso, ndlyo innotthceomweorinkincgonetancvtirwonimthenhta.zaTrdhoeusmoinst --coims mraopnidployllutrtiaunmt pohfionugr ablrleaotvheirngthaeir--wotorbldaccwoitshmothkee drioscintogrssttaankdeatrodwoafrnlimvinangk, inind ospf iittes doafngtheer. Tefhfoertasutwoe mpoolbluiltee itnhdeusatirry oifs pthreodturacfifnicg rcoaardssi.nWairthapitdhetegmropwointgo ppoowpuelratiaonnd cehnetaetrins,g,anmd otrheeirpoinllcurteaanstesd eunseteorf tfhueel afiorr. Bhaavceternioast,dvisiraupspeesa, rsepdonegitehse,r.anTdhuost,htehresemnavlilroonrmgaennistmosf Wmahnil,ewtihthe rgerfeeraetnceenetmo ylunogfs,thies clhuannggsi,ngtubcoernctuinlousoiuss,lyis. gnreawduiamllpyodrtiasnacpepetaorintgh,e naeiwr idmispeausreitsieasr.e Carhirsoinngic, gbivroinng mchuitcihs, amstohrme a,imempoprhtyasnetmdai,saeansdeslunthgancantcuebreracrueloalsriesadiyn cliovuinngtrisetsanwdaitrhd.highly developed industry and a high enMviraonnmhimenstelaflsaondretqhueircehaantgteinngtioonf. hAisllreeragcietisonarteo othnee pinrgobloermga,nifsomr sextahmropuleg.hTthhee draenspgierratoofryallaenrgdendsigaefsfteicvte omregdaincsineasn,dfotohdes, sckoisnmeisticcso, netticn.,uoaureslycominmcroenasianllge;rgneenws. Abrleleartghiicngreaocrtgioannss aarnedimthpeoirrtaonbtvwiohuesn cwonenceocntisoinderwtihthe tdhiseeaasiers iomf ptuhreitileusn.gsMoacncyurofontlhye acfhterronaiclooncgcuepxaptoiosunrael otifmet.heWsee dairseeagserasduaamlloyn,ghotwhoesveer,ococbusepravtiiongnalthegrsoiugpnss which have been exposed for some length of time. is Oaulrreakdnyowflaeidrglye ocfommapnleytef:actIorsaminfltuheinnckiinngg thoenllyungosf ainsbjuersiteoss,is;sutchhoseasmcahnlyor choerminciatlrsoucsaufsuinmgesa; cuatned lutnhge doiusreaksensowclaeudsgeed isbystibllacvteerryia,ressptroincgteeds,, aonrdvitrhueseisn.teOrpftreen tthatiisoniss tirnuemoafnyallienrdgiivcidduisaelasceasseasnadrechdrioffnicicultbrtoonmchaikties:, alunndg escpaencciearl,lyemofphthyesermoale, oafndnofnipbrroosfiesssioonnatlheandwhporloe, fheasvseio, nwalithensvpiercoinaml eanptpsreicniatitohneirtooGccruerartenBcer.itaYine'ts ewxe cpeolslaelnt ovfitatlhestarteislatitciso,nsimhipporbtaentwt eeevnideonccceupaattioonur adnisd ceArtaftienr puthlims ongaernyerdalisesauservs,eys,ucnhoaws clhetronuisc bstruodnychitthise. dcoetnanilesc.tioSnin, cIeshsaillilcobseisginwwillithbeasbdeisstcoussiss.ed in another Asbestosis asbTehsteosmisajiosrcpoanrttaionfeodurinprtehseenetxkcneollwenltedGgeercmonancerbnoinokg LthuantgeanppbeyareBdohsloigm-eJacmobo-nMthisillearg.o,ThDiise bAosobkesctoosnetaidnesr, ipnracatdicdailtliyon thtoe 7e0n0tiroef wthoerilrd olwitneractausrees, irnefetrheinscesfieltdo (asboomuet 6th5e0 preaftehroegnecnese)s.isT, hcelirneic,ispnroogthnionsgis,baasnidcalplyrevneenw otibotnainoefdthaibsoduitsetahsee. frFeuqrutehnecryinofforcmlinaitcioaln siysm, phtoowmesvears, wfroelml atshreoaeunttgheonrso'locgaircefaunl dexbarmoninchatoigonrapohnicthoebirsemrvaatteiroinasl olufn7g00cacnacseers.isTshteillresltaattiiostnicsahlilpy binedtweteeernmiansebdes.toIsnisspanitde othfetihrios,w"nassbpeesctiofiscactaionncetro" iet.xists, and the authors give affDecotesas,asfboerstoexsamdupslet, hbaevryellisuimm?ilaTr hinsonisocacuppraotibolenmal nthoantochcauspbaetieonnaelxpopsleedurathl rocuaglchiftihcaetioobnsercvaasetison(sso-ocfal1le2d6 nlaetiigohnbolirvhionogdacroasuens)d thtwaot hoapdenbeaesnbefsotousndquinarrtihees,poppuub lsitsuhdeyd, tbhye tdheetaFilisnnofiswh hDicrh. Kthievialuuothtoo.rAwcicllorpdriensgenttohtihmis stieolfn actastehsisweCroenfgoruenssd, imnotrhee tmhainnut8e00x-praleyuirnavlesctailgcaiftiicoan oanf yfaromcceursp,atwioonraklmeenx,poasnudre.theCiar lcwifiviceast,iownhowansevuesruahlalyd olocccautpedatioinnaplaarisebteasltopsilse.urIan, amsositt iisnsatlasnocemsoistt oocftceunrreidn absiltaintearlallcyalcoinficathtieoninwnaesr cahlseost owftaelnl. oBbassearlveadn,d ampeudli mcaolcniafircyatfioibnrowsiass bneoitnicgedfoutondapopnelayr oslnowalyf.ewThceasseesr.oTenhte giceanlolsoygmicpatlolymns.otiTcheaebsele ochbasnergveastigoanvse imnsaikgenifiitcanevt icdleinnt ttihoant omfetahseureensvmirounstmbeentstaskuernrotuonpdrienvgenthtethfaectaoirriepsoallnud aarsebemstoostivqautaiorrniefso.r TsihmeilraersiunhvsesotifgaDtiro. nKs iivnilouothtoe'rs cwouornk tries to certify these observations. NORO 327 Ocotnhieorsiisi"brotiucseludnbgydissieliacsaetsesa,nmd i"xbedenoigrnnponne-usimlicoa cdaursbtosru(Gndlausms ,wocoelm, esnetr,iaFteu,llesirl'lsimeaanrtihte,, cthailcn,a aannthdrabcoalll, mclaicyas,, Tghroapmhaiste,(bagsyicp)susmla,g, keatco.l)in, limestone, marble, talIcossihsalalndpasgsratphhisitegrlounugp, wwihthichaarberiesftillmoebnjteioctns ooff dcoonutbitneudolyus, trheesedarucshts. Wofitthhisgrgeraotuepnhoauvgeh tehxepior saufrfee,ctuinn wthiethocicmurprreonvceedofhyfigbireonseis. tHheosweevteyrp,eist iosf evpiudlemntontahrayt changes will become more and more rare. Pneumopathies due to toxic chemicals and metals deGsmasoedsu, r,F uhmydersocaanrdboVnsa,pooirlss, (kCerl,osNen0e,2,etSc.0) 2, borans, cadMmeituamls, c(hArloumm,incioubma,lt, afnltuiomr,ong,oldb,ariiruomn,, mbaenrgyallniuesme,, ntiitcakneilu, mo,smvaiunmad,iupmla,tiwnuomlfr,amse,lezniricuomn,iusmu,lfeutrc,.) tungsten, ingThteheamlouunngst oifs tocxoincticnhueomuisclayls garnodwimnge.talVs ainnaflduieunmc, ecshpreocmia,llayndinbeSrwyleldiuemn ahnadve inbeeonursuhbojescttscoouf nrtersye,artchhe, cUr.eSa.sAin. gT. hIet iims pnoerctaensscaeryo, fhvoawneavdeiru,mtoisbeesapreciinallymiinnd othilatcowmitihngthferoemxpvaanrdioinugs upsaertosf oofilthheeatwinogr,ldthceonctrauidnes vacaincadsiuulmfurincovmerpyoudnifdfesreinnt atmheouansths.esThise arlosloe otof thbee wreomueldmbreerfeedr. yoFuortoathdeetpariolecdeedsitnugdsy ofofthbeercyolnlifuemre,nceI Hheeladltha)-t, tahecomMp.Ir.eTh.enisnive19l5is8t o(Af .Mref.Aer.enAcerscho. nInbdeurystl. ilniugms. WisecionntEauinreodpei,ntoa mpyubklnicoawtlieodngeo,ndothnesoet hparvoecetehde bthige Upr.So.bAle. ms with beryllium which seem to exist in allItthies inmewposcshiebmlei,cainls twhiitshsihrorirttanptreesfefnectattioonn,thteo lnuanmgse. Wteme pitnindgusttoriaelvaplhuyasteicitahnes ahftaevreeffsepcetscioalf adcifuftiecuiltrireistanatts wtoiththerelfuenregnsce(nittorouetsiofloumgiecs,diCffle,reSnOti?a,l etdci.a)g, neosspteiccsialilny chronic bronchitis and emphysema. pPnneeuummoompaytchoiseessdu(eActtoinoomrgyacnoiscis,duasstpse, raglillelorsgise,nscoacncdi ddyioeisd,omfeyactohseirss,,cofrlkou(sr,ubegrroasiins,), cgoutmton a(cbaycsisain, oshisa)i,r,druhgasy, b(foasrims),er'slinleunn,g),mohnisitloiapsliass,monsoisc,ardjuiotesi,s, lesapthoeror tri(cchaonsnias-, sugar cane (bagassosis),- tobacco (tabaccosis), tropical woTohdse, eatgcr.)icultural population has received increased oafttethnetiorenladtiuorninshgipthbeeltawsetefnewwoyrekarasnidn htehaeltihn.ve"Fstaigrmatieorn's ltuunreg"haanvde optrhoevredpuslmuropnriasriyngdlyiseacsoems mfoounndupinonagcrliocsuelr ipnovweestrisgatotioinnsv.eUstingfaotretutnhaetseelyc,osnodfiatirotnhserien htahveecnooutnbtreieens where the agricultural population works under the wedogrest ahbyoguitentihcecopnudlmitioonnas.ryWdeisheaavsees no6ft tehneo uwgohrkkenroswiln theThoeldeAffseicatnmrieccehamniisllms, foofr mexoastmoprleg.anic dusts is still buancctleerairo,loagnydanwde aallreergaollsoogyinwiall dbieffiocufltmuficehld,hewlpheirne --sevaecruatle,cassuebsa. cWuthe,atchfarocntoicrs; epfrfoetcetinins,dailfcfaelroeindts,ciornridtiattiionngs imncelcuhdaendic--afarectoqrsu,esttoioxnics, tahlaletrgairce, sbtailclterwiaa,itinthge tosilibcea wanisthwebryedss.inIonsisaidsdsittiiolln,cofnotrradeixcatomryplei,n tdhieffeerexnptercieonucne torfieEs.ngTlhaendinmtearkeestionnge rethseinakrchthraetsuthltiss odfisDears.eShcahsillninogt ymeyt dowisnapcpoeuanretrdy.as has been contemporary thought in aInncfheycltoiostuosmaosnids, paanrtharsaitxa,ibpilnheaurzmioosipsa, tbhruiecsell(oAsmis,ebhiyadsias-, etittco.)sis, leptospirosis, ornithosis, tuberculosis, tularaemia, difWficiuthltiethseindiseetaioselosgoicf tdhiiasgngorostuicps:thwerheenareisctohnetininufoeucs qtiuoensttioonbeiscovnersyideirmedpodrutaentt,o fwoorrkexaanmdplwe,hewnitnhot?tuTbehre caunldospisn.eOumf ococuornsieo,sethseisreulnatdieornschoinpstbaenttwseteundyt.uberculosis cLhuronmg actaesn,ceirsodpuroeptyol ocaclcuophaotliomn anu(Afarcsteunri,nga,sbneisctkoesl,, radTihoaectSivecerestuabrystaGnceense,raeltco.)f our Congress, Dr. Eckardt, hreanncdeleosf thcaencroerleinofhwisorbkoionkg Icnodnudsittrioianls Cinarctihneogoecnceusirs smuospstecvtaerdietdhlyat ainndinwdiuthstrgyoomdacnryitioctihsmer. sYuebtstiatnicsestoalbsoe fhiaevlde, ahowcaenvceerr,ogisensetitlilc veefrfyectl.imOituerd,kannodwleadltgheouignh tehxis pineripmraecntitcael cnaencceessrarryesefaacrctsh. Ihtasisgohnoepefdar,thwate tshtiellwlaecllkewnidllowmeodrecatnhcaenl obregfoanreizactoionncsernandthermesseealvrcehs winistthitutthees ocTcuhpeatiroensualltsasfpreocmts itnhethienveetsiotilgoagtyioonf bcyancUe.rS.. Public Hmeinaeltrhs Sareerviecxepeccotnecderwniinthg tghreeaht aiznatredrsesot.f Wradhieatthioenr sthtoe icnasetsheofveSrcyhnweiedbeesrpgreaandd uJroaancihuimmstmalinwinilgl gisetasuqcuceesstsioorns that will presently be answered. Pneumopathies caused by radiation alrTeahdeyinbfeluenencreefeorfreradditaotiaobnovase. thOeucrakusneowoflecdagnecearbohuast sthmeallo.thIenr ceofnfencetcstioofn rawdiitahtiothneroapny,thleargluengdsoseasre(1v0e0r0y 2in000thre.) fhoarmve boefepnnfeouumndontiotiscaaunsed cfhiabnrogseiss.inFrtohme luEnagsst Gmeornmiaancyasethoefrea ccohmemesistt,hwe hriecpholretdotfo adecahthro; ntihce pcnaeuuse odfusdteoatvherbaeinpgercioodnsiodfer2e0d ytehaers.breathing of radioactive Conclusion daTtioonouforrprtheseentteckhnnoicwalledpgree,vwenetiaolnreaodfythheasvee daisefoasuens. Wpreevaernetioasn:yewteinknaowweatokoerlpitotlseitiaobnouast twohytheoinrempeedriscoanl gmeutschthreemseaarcnhd. one does not. This question requires diaWgneoshtaicvseoaflrtehaedypulrmeaocnhaerdy fdairseainsest,haendroethnetgreenwoleogariec mofakthineg dcioffnicsutaltnitesprtohgerreesisn. Wase taoreseavlseoralawoafret,hehodwiseevaesre, ggeronuoplosgircefeexraremdintaotioanbowvee. mTuosgtedtheevrelowpitohthtehre clrioneicnatl 328 MEDICAL PRACTICES efuxnacmtiionnatidoinagmnoestthicosd.s,Inespitesciamlloyst thaedvpahnycseidolofgoircm,luwnge halal,teintothaeppfliyeldit enxoatmoinnalytioinns ltaobotrhaetoreixeasmbiunta,tioabnovoef poApubolavteionallg, rwouepsneeexdpoaslesod itno dthifisferfeienltd ekxepeonsuirnest.erna ttoioneaxlchcaonllgaeboinraftoiromnattoiosnolsvoe tohuart ceoamchmoonf upsroibnlehmiss oawndn caolruenadtryy pcoosusledss aptoplythein bpertatecrtimceenttheofknoouwrlewdgoerkiwnge population. BIBLIOGRAPHY General 1. Pneumoconiosis Abstracts, Vol. Ill, London, 1959. 2. pSaathnicees spprocfiaelsesiocnoenlsleacsr(Sl ilicol'setudexecedpetsep).neAurmcho, mal. prof., 75:253-354, 1957. 3. Almlbeasharpyo,sCs.: pLoeusr alsethumr erspparorafteisosnio.neAllrecsh:. pmroabl. 4. pArlotsf.h,u1le5r:4, 1,B6.3;3,Y1a9r5m7.us, L.; Palmes, E. D.; and Nreeslpsiorna,torNy.: trAacetr.osAol.Md.Aep. oAsirtciohn. Iinndutshte. Hheuamltahn, 5. A15n:2d9e3rs,, 19W57.:. Soziale Probleme bei allergischen EOrfkf.raGneksudn. gdeiennastm, 7B9e:4is8p8i,el1d95e8r.Asthma bronchiale, 6. oAfnddeirssaobnil,itWy . iHn.,caonadl Smcihnmerisdt,wWith. F.c:hErovnailcuaptiuonl 7. Amnotnwaeryiledr,iseHas.e:. JM.Aa.sMtz.eAll.e,n77u7:n1d45,H1i9s5ta9m. in nach pInajtehc.t,io7n6:6v0o7n, 1S9t5a9u.bsuspensionen. Arch. Gewerbe8. bBeapaadtehro,loEg. iWe .(:LuEningiegneemnepuheysPermob, leKmaedmdieurmG, eDweesr mstaoddtu,r)1.95B6e,iph.. z1.72Z.bl. Arbeitsmed., Heft 3. Darm 9. Binegrksaonnd, Jc.:anTcehre osftattihsteicalul nign.vePstriogca.tioSntafoff Msmeeotk., 10. MBearyloin,ClRina.,g5n4a:r2:06Y, r1k9e5s9p.neumokonioser. Svenska 11. LBekrnaarrtdid-Gnirnifgfeitnh,s,55:M31m5.7-3C1.-;71,Ch19a5m6.peix, J., and dBeasldim'nio,isAis.:suAressth(ma epprroopfoesssiodneal2p4arobcosenrtvaacttioanvse)c. 12. ABrucghy.i,mBa.:l. Bperiotfr.,g1e8:z2u,1r2.F, r1a9g5e7.der Staubretentions fhigkeit der Lunge. Munkavdelem, 5:49, 1957. 13. CFraonuccehlltam, aLn.,DRe .;C.;LBfafaledre,r,WE..; WW.;oCrthho,uxG,.;J. aDned; Zmoernnt,arOy.:oInndcuusrtrreinatl pdrisoebalseemsso.fDtihse. Cchheesstt:, a52c:6o8m3, 14. C19a5r7s.tens, M.: Die asthmatischen Reaktionen der Bergleute. Arch. Gewerbepath., 15'Ab, 1956. 15. CEmarpstheynsse,mMu.:ndZBurronFcrhaigties ddeerr BKeragulseaultiet. t Arvcohn. Gewerbepath., 75:285, 1957. 16. Dhoarusttr,eWba.n:dLe,unLg.;deBpeocskitmioannno,f fHin.e; daunsdt pWaratilckleens. A.M.A. Arch. Indust. Health, 76:179, 1957. 17. Dphayvsieicsa,lCp.roNc.e:ssD. eIpnostihtieonSyomfpdousisutminotnheInlduunsgtsr:iaal. PLuolnmdoonna, r1y96D0,ispe.as4e4s., ed. by King and Fletcher. 18. nDtianldniearg, noLs.e: dKelrinLisucnhgrenntkgreannoklhoegiitsecnh.e StDutitfgfearret, 19. D195n8n, epr., 3L62.:. Emphysem bei Staublungenerkran- kkuranngkhne--it. EZmblp.hAysrebm. maelds., s7e:l1b3s7t,n1d9i5g7e. Berufs -- 20. kDrannnkeurn,gLe.n: PdneeruLmuoncgoen?ioKsernitioscdheer SBtaeutrbalcuhntguenngeern umnedd.,V9o:r1s2c,hl19g5e9.zu ihrer Entschdigung. Zbl. Arb. 21. Freeirniing,unJ.g, daenrdLuUnlgehelovvon, SVta.:ubUuenbderihdriee BSeesltbimst m19u5n9.g in Tierversuch. Arch. Gewerbepath., 76:630, 22. Fchlertocnhiecr,brCo.ncMhi.t:isDiinsabreilliatytionandto mduosrttaleitxyposfruorme. A.M.A. Indust. Health., 75:368, 1958. 23. Fmloectcohneior,sisC.. InM.t:heRaSdyimolpoogsiicuaml doinagInnodsuisstorifalpnPeuul mdoonn,ar1y96D0,ispe.as7e2s., ed. by King and Fletcher. Lon 24. GanedrnVezo-iRsiine,uxC,.: CA.;n oBfatelgnaiurinerse,coEg.n;izFedoumrnaineirf,esPta.; tfiaocntioonf ponfeupmseoucodnoitousmisorianl mfoinremrsa:tioansse.ptiScemliqauinee Jh.oAp..M.AP.a,ri7s6,7:25144:01,08119-5180.89, 1958 (in French). 25. aGuefrsivnegr,scRh.i:edDeniee fSrtahuebnartReneakitmionveenrgdleeirchLenudnegne 26. 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IBnodbuislet.vaM, eAd..,X1.2:e4t3,at1.:955T.h e A m o u n t of D ust in RtheesiCdehniltdiarel nDs iHstreiaclttsh.ofGiAg.sbiesLtanan.,d27i(ts9),Ef1f9e5c8t. on 8. ABsobhelsigto,seHd.;erJaLcuonbg, enG..;StaunttdgarMt (Tllherie, mHe).,: 1D96i0e (166 pages). 330 MEDICAL PRACTICES 9. SBchowhleigrs,pHat.m: Slclehrw. ePreroMc.isXchIsItaIunbts.iliCkoosnegrb. eiOecicnuepm. 10. HBreiadlgteh-,DHaveilss,inSk.;i, a3n:3d10N,a1g9e5ls7c. hmidt, G.: A report oinn tphuereablsiemnecsetoonfep. nBeurmit.ocJo.niIonsdisusatm. oMngedw.,or1k1e:r6s, 11. D19j5u6r.icic, I., and Savic, V.: La microhematurie des oPurovcr.ierXsIIdaInnst.uCneonmgri.neOcectupu.neHeuaslinthe, dH'aeslbsiensktei,. 12. 3E:h32rh4a, r1d9t5,7W. ., and Heidemann, W.: Zur Klinier rubnedpaPtaht.hoGloegwieerbdeehryOg.c, k1e7r:s5t0a4u,bl1u9n5g9e.. Arch. Gewe- 13. kFuehnrgee,n Win.:folgUeebbererudfloicphpeerlseiStitgauebePinlweuirrakvuenrgkeanl. Fortschr. 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ZKbole.lsAcrhb,.Fm.: eDd.i,e9S:t1a5u3b-1g5e7f,h1r95u9.ng durch Flusspat. 22. gKeinvoilluoogtioc,siRgn.: oPf lneounra-ol cccualpcaiftiiocantaiol nenadsemaicroanetnot- p(6h7ylpliatgee-ass).bestosis. Acta Radiol., Suppl. 194, 1960, 23. TLalckhutrmacuhnt,d SHt,,eatiat,ndihreScBhemziiedht,ungKe.n zGu.:m AUsebbeesrt svoewrsiuechiharen WRaitrtkeunn. gBebietrim. Siilniktorasterfaocrshcthea.,le6n1, T19ie59r. 24. LNobrldimcha,nnH, .-JM.;.: KDocieh, RWe.s;orpStifofnge, eiKn.v-eHr.l;eibatnedn 5S0ta:1u,be1s9.5F7.einkrnige Stube. Beitr. Silikoseforsch., 25. RMoassss.iomneed, .RI.n,daunsdt., L(Tuvoorinnio, ),R.2:5:S1i,li1c9o5s6i. da Mica? 26. PMreoick.leXjoIhIn,IntA. .:CoCngarr.boOnccuapn.d Hpenaeltuhm, oHcoenlsiionskisi., 3:335, 1957. 27. mMoenssairtye, Jt.a;lcRoseisd,dina, cGl.i;niacnald aKnldeinefenlvdi,roMnm.: ePnutall study. A.M.A. Arch. Indust. Health, 20:408, 1959. 28. Mpoolvnegreelli-dSicicaenmnaemnteoo,rilNie.v:i Sculinilcao-rpaadtioollooggiiaci dsua 350 cementisti. 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AS..;Ma.An.dAMrchac.MInadhuosnt., 37. SHeepakleth, , 1G9.::392Z, u1r959.Talkumstaublunge. Tuberk ulosearzt, 34:247, 1960. 38. sWchamtsoidnt,, AG..:J.P;nBeulamcok,coJn.;ioDsiosigin, AC.aFrb.;onanEdleNctargoedle Makers. Brit. J. Indust. Med., 16:TIA, 1959. 39. VLuysnkgoecnilf,unJk.t:ionDenynabmeiischZeemVeenrtanrbdeeirtuenrngendurdcehr wseine.dPerrhaoclotvenUi nletke.r,su8:c8h5u,n1g9e5n6. nach 5 Jahren erwie Pneumopathies due to toxic chemicals and metals 1. hBeelrdyllaiutmMDasissaecahseuseatntsd IIntsstitCuotentroofl. TCeocnhfneorleongcye S19e:p9t1. -3206-7O, c1t.9519,. 1958. A.M.A. Arch. Indust. Health, 2. Agumindeuar, pMigsaryto Osu.:lfuTrhice arceisdpimraitsot.ryA.rMes.pAo.nsAercohf. 3. IAnrdcuhsatn.gHelesaklatjha,, 1L8:.40N7,. 19&58.Borisenkowa, R. V.: vUonnterIsnudcuhsutnrigeesntaubberaudsie Mhyegtaielnl-iLscehgeierBuenwgeenrt.unJg. H19y5g7.. Epid. Microbiol. Immunol. (Prague), 3:441, 4. BMaeadd.eSr,acEh.veWrs.t:.,L5u2n:1g2e8n,sc1h956d.en durch Isozyanate. 5. bBlauandgeern, eErk. rWan.k: uHngaertnm, eBtaalln-dLu3n.geEnd.. Ibny DJietteSntau& mKelods.t,e9rk:33tt,er1,95D9.armstadt, 1958, p. 531; Zbl. Arb. 6. Bfsakardanerk,heEi.teWn,.:SNicehueeres Abrbereitd,ie3:w23ic, h1ti9g6s0t.en Beru 7. BAalurtmh,inGiu.m; Flurnikg,e.WD.; tsacnhd. SMcheedi.deWmsacnhdre.l,, #H3.::11D1i5e, , 8. B19e5c6k.lake, M. R.; Goldmann, H. L; Rae-Bosman, eAx.;poasnudre Ftroeckn,itrCo.usC.:fuTmhese. lAonmg.-teRremv. efTfeucbtesrco.f, 76:398, 1957. 9. wBietnhoiastr,gCon. -Pa.r,chandweFlrdainngt,. RP.:roMc.edXicIIal Ienxtp.erCieonncgers. 10. OBicsctuerp,. FH.;eaKltlhav, iHs,elGsi.;nkKi,o3h:l3e8r,7,H1.9;57a.nd Wittgens, Hau.:f ZZiunrkcGhreowmearbtbeatosixsi.kAolrocghi.eGveownerAbenpstartihc.h,s1st6o:f5f6e7n, 11. B19l5o8o.m, G., and Swensson, A.: The reaction of the sthioronsmboofcytseusbmtoicrionstcroapviecnoupsalryticliensj.ectAedctasusMpeend. 12. SBcoacncdia.,, 1D6.2:A2P3a,to1l9o5g8i.a de la soldadura elctrica. 13. MBoendn. eTilr,aJb.ajAo.,; 2K3a:1z6a,nt1z9is5,8.G.; and King, E. A.: A fooxlildoew-fuupmes.tuBdryit. oJ.f Inmdeunst.exMpeods.e,d16t:o135c,a1d9m59iu.m 14. Bpirctcuhrenero,f Lpn. eu&moMcoanuitonseirs, inB.:weBldreornsc.hPograracpohvniei lekarstvi, IV.233, 1959. 15. NBoedot., TAs.chCr..: GVeenregeisftku.,ng101m:2it12V4,an1a9d5i7u.mpentoxyd. 16. Btiorensliinn, bAe.ryJl.l,iuamndfaHcialirtriiess,. WSu.mBm.:aHryeoalfthtenpryoetearcs o19f:5e9x6,pe1r9i5e9n.ce. A.M.A. Arch. Indust. Health, 17. cBhuieaslse, uHn.d, aasnthdmLoeidrneeBr,roRn.c:hiUtiesbinerdAerstchhmema isbcrhoenn 18. ICnadmusptbreiell., ZI.rePnrevRe.n;tivCmasesd,.J(.ZSu.r;icCh)h,ol5a9k,, 1J9.5;6.and MKeahno.e,AR.M. .AA..: AArlcuhm. inIunmdusitn. tHheeaEltnhv,ir7o5n:m40e4n-4t0o6f, 1957. 19. CPuelmmboenr,arHy .; eWffeacttssonf,roJm. A.r;adainodactGivreucctih, aTll.iumB.-: ' Hacetiavlathte,d75:c4l4ay9, p19a5r7ti.cles. A.M.A. Arch. Indust. 20. AC.hMol.aAk., AJr.:chT. hIneduansta.lyHsiesalotfh,tr1a9c:e2s05o,f19b5e9r.yllium. 21. pCohirsiosnteinnsge.n,A.FM. .CA.., aAnrdch.OlIsnodnu, sEt.. CH.e:aClthad, m1i6u:m0, 1957. 22. wCoitthter,edLa. thHa.m: iTl reacatmlceiunmt ofdicsaoddmiuimum. pJo.Ais.oMn.iAn.g, 23. 7C6r6e:p7e3t5,, M19.5,8.and Gaffuri, E.: A proposito della mnaafltaat.tiLaavdoaro nea.vmadedis., 1n0e,i 19p5u6l.itori di caldaie a 24. anCdurtiRs,asJm.uKss.e;n,BaHue.r, KH.:elePnue:lmLoonoamryansd,ifSfuasliloien: ccaarpbaocnity msotundoixeisd.e Ib. reaaths-ihmoplldifiniegd. Atemch. nJiq. uMe eodf. 25. DSeai.l,h2a5m6n:5,3T, .1:9C58h.lorine dioxide toxicity in animal Ienxdpuersitm. Henetaslthan, d75:i1n0d1u,st1r9i5a7l. risks. A.M.A. Arch. 26. DG.eicEh.m: aAncnu,teWe.fBfe.c;tsKoefplinnigtreor-,oMlef.inLs.; uapnodnLeaxnpieerr,i 7m5e:3n1ta2l, 1a9n5i8m. als. A.M.A. Arch. Indust. Health, 27. DdernschSei,nteHr.a:nlZagurenFrasgaearldenrdiSsctahuebrgeEfisherdnuhngtteinn w19e5r9k.e. Arch. Gewerbepath. Gewerbehyg., 76:666, 28. Dnonn-npenre,umL.o, caonndioHticarlduyn,gRl.e:siPonnesudmuoecotoniiontihcalainndg xd-ursaty anadndSO, mfuomrbeisd-farnoamtombuicrnalingstcuodkiee.s.CliAnirccahl., Gewerbepath. Gewerbehyg., 76:644, 1959. 29. uEnhdrlicahrebre,itHsm., eadnizdinPiisbczh,eWM.: aIsnsdnuashtmrieehnygbieeniiscdheer Vscehruwtze,nd27u6n,g1v9o5n6 I&so7z,ya1n95a7te.n (Desmodur). Arbeits 30. FCiasdchmeiru,mR,.QEu.e:ckGseilwbeerr,blAicrhseenVuenrgdifithunregeVnerdbuirncdh u1n94g6enb.is U19e5b6e.rsCiclhaut sthbael-rZedllieerfeVlde,r1f9fe5n8.tlSicchhurnifgteenn dB.ergGleeusteellsec.Vha.,ftHeDfteu6ts(c20h2erpagMese)t.allhtten- und 31. rFeriineebmel, PHh.t,alasnudreGanrohsysd, riEd.: uZnudr RToohxpizriotdtukvteonn aGueswedrebrepiantdhu.,st7r4ie:4ll6e5n, 1P95h6t.alsauresynthese. Arch. 32. Fderinebedlu,rHch., anneduaLrtigcehtrLaathc,keH.u: nGdesSucnhdahuemitsstsocfhfe. Dtsch. med. Wschr., 54:980, 1956. 33. Feirniefabcehl,e HC.,heamndikaSltieeinn, hAe.r:vZorugrerGuefneneseen dAesstdhumracsh. pVaetrhs.u,ch76e:6m20it, 1p9-5P9h.enylendiamin. Arch. Gewerbe 34. Fmriiubmerg,poLi.s:onEindga.thaAm.Mil.Ac.alcAirucmh-.diIsnodduiustm. Hineaclathd, 75:18, 1956. 35. Fmriiubmergi,n Lm.:anDienpocshitrioonnicapnodisodnisitnrgib. uAt.iMon.Ao.fAcrcahd. Indust. Health, 16:27, 1957. 36. AFrricbhe.rgIn, dLu.:st.CHhreoanlitch,c2a0d:m40iu1,m19p5o9i.soning. A.M.A. 37. vGaapgoeu, r.J.BriCt..:J.TIhnedustto.xMiceitdy., o76f:1e1p, o1c9h5l9o.rhydrin 38. FG.a:lyP,nPe.u;mRoonciehe,chLr.o;nBiqouueviienr,teJrs.;titaienldle Pdeirfrfiuns,e L. Aevrochlu.timonal.mproortfe.,ll7e5:c3h0e1z, 1t9in57.metalliseur au zinc. 39. fGrolmmmceh,lJo.r,inaend dLiuonxdidger.enA, .KM.-.DA..: HAeraclht.h hIanzdaursdts. Health, 76:169, 1957. 40. GUlntmermsuec,hJu.,nagnedn Swbeenrssdoenn, AS.:taTuibereinxpdeerirmAenrtbeelilte sluatnmgeonsperhkrraenkuvnognen,FeBraronsdili3z.iuHmewraeurksgen. .JtStteanub& Klosterktter, 1957. 41. aGlulmmiomseis, Ja.,ndandpnSewumenoscsoonn,ioAs.i:s Ciansesthoef stiudnegrostseisn, ccaurpb.idHeeatoltohl, iHndelussitnrkyi., P5:r1o6c6.,X1I9I57I.nt. Congr. Oc42- bGaormiubmos,duBs.:t. PPurlamcoovnnairyLenkoadrustlvait,io9n:39b9y, i1n9h5a9l.ing 43. rGernacye,, Et.oxLiecBit.y:, Ohxaizdaersd.ofAn.Mitr.oAg.enA: rtchhe.ir Inodccuusrt. Health, 7P:479, 1959. 44. PHraogcl.inXd,II OI.n: t.LuCnogngcr.haOngcecsupi.nHeelaecltthri,c Hweelsldinekrsi,. 45. 5H:1a6m9a,,1G95.7.M.: Symptoms in Workers Exposed to I1s9o5c7y.anates. AM.A. Arch. Indust. Health, 76:232. 46. H19a5m9.lin, L. E.: Siderosis. J. Oceup. Med., 7:79, 47. oHvaemr lainp,eLri.odE.o: fSeiidgehrtosyise:arasdodnitisoixntayl-noinbesefrovuatnidornys c1l9e5a9n.ing room employees. J. Occup. Med., 7:79, 48. sHeaasred.yJ,.HC.hrLo.,n.anDdiseSatsoee,c9k:le1,52J,. 1D95.:9.Beryllium di 49. nHoassiesgaovfa, cKh.ro(naincd Tsuelipsihnugrer,dJio.,xdidisecusinsitoonx)i:caDtiioang. 5P:r2o7c1., X19I5I7.Int. Congr. Occup. Health, Helsinki, 50. HGuewsteernb,epKa.t:h.H, a7r6t:m72e1ta,ll1-9F5i9b.rose der lunge. Arch. 51. Icaanzinoanceonaec,utAa.,daandanMhiadzreildlae dmiaBleoisccao,inMl.:avIonrtaotsosrii 52. Jdoehl npsotortnoe., LRa.v.Tu.:mTaonloue(nNea-2p.o4l-iD),ii5s:o4c0y4a,n1a9te5.6.clin 53. iKcaalrpfoeva,turBes.. IDn.d:usAt.nMgaebde.n, 26z:3u3r, 1to9x57ik.ologischen 2C2h:1a4ra4k:7te4r,is1t9ik57v. on Methylchlorakrylat. Gig. i San. 54. dKearspHareorvs,teAll.uAng.: PvroonblVemulekadneirsaAtirobnesiatskhzyegleieranteorbeeni 55. K(Tlaiuvrisa,mG, .:KaApmtakmso).niGakigv.ertrguifdtuan, g7e:2n4,u1n9d57i.hre Fo Algrecnh. uTnotxeircolB.,e7r7:c1k5s5i,ch1t9ig58u.ng neuer Kasuist'ik. 56. UKlrasvaicsh,e Gd.;er KThholemr,assHch.;lacaknednpnBeiusmtero,nieF.:unDteier mbeasnognadnehrearltigBeenrcSkcshilcahctkigeunnbgestadnedrteVilea.naAdrinch- . uGned 57. wKeleribnefpealdth, .M, 7.,5:a3n5d5,G6i0e7l,, C19h5.6-P1.9:5C7.linical manifes otaftieoxnpsoosufroez. oAnme .poJ.isMoneidn.g:Scr.e, p2o5r7t:6o3f8,a 1n9e5w6. source 332 MEDICAL PRACTICES 58. kKaoreblisdceh, uFn.d: GHeasrutmndehtaeliltes.schZbdl.enArdbu. rcmhed.M, e9t:a3l3l, 1959; ]. prophyl. Med. Soz.-hyg., 3:1, 1959. 59. SKtuanbkileel,, DA..E.M; .S; auMnduerrths,a,J. EP..; Fa.;ndDWikielmls,usJ,. HH..:; ASormche. pInhdarumsta.cHoleoaglitcha,l 1e3ff:3ec4t6s, o1f95d6i.borane. A.M.A. 60. fKtuuntsgchdeurar,chW.D: isEsionusegiagse.nMartiitgt,erosFtaelrlr.eiSnaenr Vveerrwgi., 61. 5L7a:c2h2n8,it,19V5.6:. Zur Therapie der Reizgasvergiftung. 62. /L.beli.chAerrb, . Fm.:ed.Z, u8r:17D7,if1fe9r5e8n.tialdiagnose zwischen ARolunmlgienniustmr.l,u8n-g1:e571u,n1d956M. orbus Boeck. Fortschr. 63. DLeisvtirnisbkuatsi,onG. aJ.n;dPoelxlics,reAti.o;nanodfNpoovriacnke, sW. .AJ.,,MJ.rA.:. Arch. Indust. Health, 14:346, 1956. 64. ALe.Mwi.sA,. CA.rEch.:. TInhdeusbti.olHogeiaclathl ,ef1f9e:c4ts97o,f1v95a9n.adium. 65. iLnisnkdagrseynn,pSu.nkAte.,r apnad fSrawmensstsollnn,inAg.: oYchrkebsemaerbdeict-- ning av plaster. Sv. Lkartidningen, 55:2227, 1958. 66. fLirngnednr,inMgaarrie-iaLkotutaisgen,aanedftSerundinealln,dCn.inGg.: aLvunogl-67. jLeohwalet,igHl.ufJt. ,NaonrddisFttreMemedainc,in,G5.:8:B19o7r4o,n19h5y7d. ride (dbuosrta. nHe)eailnthto, x1i6c:a5t2io3n, 1i9n57.man. A.M.A. Arch. In 68. TM.acGh.a:beCli,linMic.aEl .;pGicdtuzerledzea,ndE. wGo.;rkandcaMpagceitlyadzien, manganokoniosis. Gig. Truda, 4:48, 1960. 69. lMunagn.n,BrBi.t. TM.,eda.ndJ.,L2e:9c2u1ti,er1,95E7.. R.: Arc welder's 70. Mtoxarickist,y Jo.,f daunsdt wNiathgelusscehmofidtth,e Gin.: vSittruodydeohfydtrhoe g2e0n:3a8s3e, t1e9c5h9n. ique. A.M.A. Arch. Indust. Health, 71. Mbaesrsmdainen,biWolo.:gisEcxhpeerWimireknutenlgle vUonnteVrsauncahduinnvgeern 72- Mbinasdsumnagnenn,. WAr.:chT. ieTroexxipcoerl.i,m1e6n:t1e8ll2e, 1U9n56te.rsuchun genen, dbieer bdeiie tSocxhiwkoeliossgeinschme iWt ikrakluknbgasvisocnheRnauEclhe k1t9r5o6d.en entstehen. Arch. Gewerbepath., 14:291, 73. Mbioalsosgmisacnhne, WWirk.:ungUdnetserPsoulcyhauenryglennitrils. bZe.rexpdeire. 74. MMeadss.,m1a2n7n:,40W7,.,19a5n6d. Pilgrim, K.: Das Verhalten dveosn LMunanggenagne-lwVe-bOexsyndacuhndinCtrhartoramch-lelIa-lOerxyIndj.eAktricohn. 75. GMecwLearubgehplainth, .,A1.5:2I.03,G.1:956Ir.on and other radio PopualmquoenadryustDs.iseInasetsh, eedS.ymbyposKiuinmg oanndInFdluetscthriearl. 76. MLoenikdloenjo, h1n9,60A,.,p.an1d46.Posner, E.: The effect of the uosne tohfe chalecainltehd oaflutmheinawoirnkmchainn.a Bbriistc. u]it. pInladcuinstg. 77. MMeedln.,ik1o4v:a2,29E,.19A5.7:. Angaben zur Bestimmung des zLuulftssiingeInndKuasdtrmieirumu-meunn.d GViga.ntadsiaunm., g2e1h:a2l5t,es19d5e7r. 78. dMuosztreinatlseavear,osNo.lsVo.f: wHoylgfrieanmic. Gchiga.raicStearni.s,ti2c2(o4f):2in5, 79. 1M95in7d. en, H.; Bruckner, Ch.; and Simon, J.: Bei tGraegwezrubrehCyagd.,m1i7u:m53v1e,rg1i9f5tu9.ng. Arch. Gewetbepath. 80. wMoitrckheer.ll,BJr.i:t. P]u.lmInodnuasrty. Sfiabfreotysi,s1i6n:1a2n3,a1lu95m9.inium 81. oMfitotlzeorn,eS..;AK.Min.gA,.MA.;rcahn.d IBnudruksht.arHdte,aBlt.h: ,To7x5:i1c9it1y, 82. M19o57g.ilevskaya, O. Ya.: An experimental study of ttohrey eoffregcatnso.f Graigre. imseatna.l,s2o5r:e30d, u1s9t60o.n the respira 83. LMuonsgcehninvsekri,nGde.;ruJnugreisnch,beAi .,SainndteRrehianlr,tmWe.:taDlile Arbeitern. Arch. Gewerbepath., 76:697, 1959. 84. MH.o;liatnodr, PLe.r;inMet,osGin.:geRre,chMe.r;chBesarsthuerl,lesJ.p; ouHsesyiarrets, sdiedrloasmesinopiurlmeotnalieruesr. cLaupaxceimtbopuargth, og19n5e7. (L12e7s pages). 85. LMuonsgcehninvsekri,nGde.;ruJnugreisnchb, eAi .;SianntderhRaeitimnle,taWll.a:rbDeiietern. Arch. Gewerbepath., 76:697, 1938. 86. eNraskaenxipsoksie,dS.,toanidsoNcyaamniaktei,s.S.:RSdymkpatgoamksu,in37w:9o8rk0, 1958. 87. sNuelfbaetl.unAgic, hW. .G: ewAekrubteepaVther.,gi7f5tu:5n8g1,m1i9t57D. imethyl88. SOtyananngosuirse.n,BeHni.g; n Hpandeduamd,ocoRn.i;osaisndowMinagasst,o Hin.: ahnadlatieoxnpeorfimtienntadlussttuadnides.fuImned.usIt.. eMnveidr.o,nm27e:4n2ta7l, 1958. 89. gPaennesleveri,ntRox:icaDtiioagnn.osRisepaonrdt otrfeaatmceanste.ofA.mMa.An. A:ch. Indust. Health, 76:64, 1957. 90. mPoorntealiar-eGomeqsu,elFq.u: esLaprreoadcutiitosn idneduls'tarlivelso.le Pproucl. X19I5I7.Int. Congr. Occup. Health, Helsinki, 3:311, 91. vinohnalPaotisot-nLinavgeno,ljaMaerlliee-rLoouljieshe:altLigunlgusfkta. dNororedfitsetrt Medicin, 59:290, 1958. 92. mPootneyryapeevnat,acGh.loEri.d: eT. hGeig.toTxricudpar,op2e:2rt2i,es19o5n8. anti 93. QKuloitlilnig,aPn.,: JT.hJe.;toBxoiccihtye,oRf .ozDon.;e Ffoalrky,oLu.ngHc.;hicaknsd. 94. AO.eMtt.eAl,. HAr.:chG. eIsnudnudsht.eiHtsegaelfthh,rd77u?n:1g6,d1u9r5c8h. Kunst 95. Rstoefifnel?, AWr.c:h,Ueexbpeerr.diPeatEhr.kPrahnakrumnagke.n, 2d3u2:r3c1h, T19h5o8. mbiansdsuchnlgaecnke,unVd ainhardeinUsrcshalcahcekne. Sutanudb,V7a5n:1a4d3i,nv17e7r, 96. R19o5b8e.rtson, A. J.: Pneumoconiosis due to tin omxoindae.ry IDnisetahsees,Seydm.pboysiuKmingonandInFdluestctrhiearl. LPounl 97. dRoong,er1s9, 60W, p. . N16.:8. Chronic beryllium poisoning 98. Rtreoahtresd, Lw.iCth.:cMoretitcaol-tfruompheinfe.vLearnfcreotm, 2i7n3h:a2l6i1n,g1z9i5n7c. 99. oRxoisdceh.tsAc.hMinA, .I. AVr.c: hD. aIsnVduasnta.dHiuemaltahls, i7n6d:4u2st,ri1e9ll5e7s. 2G:4if9t.2,].19H5y8g. . Epid. Microbiol. Immunol. (Prague), 100. oRfostchheinaac,tioTn. oAf.: thAenchexropmeroimmeagnntaelsitienvaenstdigamtiaognnTersuidtoac,h3ro:2m8,ite19r5e9f.ractories dust on the body. Hig. 101. RRoesspmiraantiotrhy, Jd.;iseVaoslef, iJn.; wanodrkeKrsnppfreoldmuaccinhegr, sEu.l: 102. Rphousmricanaicthid,.JP.,raacnodvnKi nlokpafersimtvia,ch9:e4r1, 1E,.:19A57.case of 103. RBaoSuOsh,,pnGe.,umJro.c: onTihoesis.toPxricaocl.oglyk.,of9:1t4h0e, b1o95ra7n. es. 104. ]R.oOwcec, uVp.. MK.e, de.t, 7a:l4:6,T1o9x5i9c.ity of propylene oxide dAertcehr.mIinndeudst.oHn eaelxthp,er7i3m:2e2n8t,al195a6n.imals. A.M.A. NORO 333 105. pRouriz,quRe.roFs.,n.andThIeribMarerdeinc,alRB. uRl.l:etiNneu(mStoapnadtaiards 106. ROuilmCyoa.n,tsNe.vJ,.),G2.0T:3.:5,O1n96t0h.e question of barytosis. Gig. i San., 27(4):17, 1958. 107. vSiaerwais, oSf.,duasntdprUodenuoce, dKi.n: eElelecctrtriconstemelicmroeslctoinpgic. 7P:r3o2c5., X19I5I7.Int. Congr. Occup. Health, Helsinki, 108. SAc.hBep.;erRs,edGli.n,WA. . HJ..;; SDcuhmrkiadnt,, JT. .GM.; .C; rDeeedlaohna, nFt,. bTi.o;loJgaiccoalbsaocnt,ionJ. oWf f.;ibearngdlas-Bpalailsetyic, dDu.st.A.A: MT.hAe. Arch. Indust. Health, 75:34, 1958. 109. 7S:c1h4n2e,i1d9e5r7, . H.: Ueber Siderose. Zbl. Arb. med., 110. fSucehlse?chNteart,. WSa.fetHy.:NeHwos,w77t:o2x8i,c19a5r8e. high energy 111. ISncdhuslet.r,MPe.d,.,e2l 7a:4l.3:2,S1ta9n5n8.osis. II. clinical study. 112. mScehntlaelr, aPn.,detmael.d:icMalansgtaundeyse aptoiasonCihnigle. aEnnvmirionne. Indust. Med., 26:167, 1957. 113. Seteraeln.:koS,aAni.taSr.;y Sctoannidsiltaivosnksy,ofY.wMor.k; Kanhdazapne,cuGl.iaLri., Atiegsloomf eprnaetiunmgopcloannitoss.isGiing.wTorrukdears, a2t:1t7h,e1I9r5o8n. ore 114. SSeomri.anho,pM., .7:4A:3s2t1h3m, e19e5x8p.rimental par l'acroline. 115. sSmimo,gV.irrMit.a,natsnd oPnattlheu,mRa.nE.:suEbfjefecctts. ofJ.pAo.Mssi.bAl.e, 765:1908, 1957. 116. aSnjdberpgo,sSs.ibGle.: Vrisaknadoifumemdupshty, scehmroa,nicAbctraoncmhietdis. Scand., 754:381, 1956. 117. Slujftbvergga,r Sm. .mG.., haonsdsoRtairgeniro,ljKee.ldGn.i:ngBsaensvlgrgnfrianngar. Nordisk Medicin, 55:1973, 1957. 118. Surminitahr,y J.caSd.m, iaunmd Kanednchp,roJt.einE.:exOcbresteirovnatiionnsmoenn Je.xpIonsdeudstt.oMceadd.m, i7u4m:24o0x,id1e957d.ust and fume. Brit. 119. SCmheimthi,caJl. aCn.d; hKisetnocrihc,alJ.poEst.;-maonrdtemSmstiuthdi,esJ.onP.a: woxoirdkemfaunmee.xpBorsietd. Jf.orIndmuasnty. Myeeadr.s, 7to4:2c4a6d, m1i9u5m7. 120. Ttheebrmocakn,agHem. eEn.t, oafndchrMonaicchlbee, ryWlli.:osiAs.dvParnocce.sXIinI Int. Congr. Occup. Health, Helsinki, 7:167, 1957. 121. VTheorgmifatsu,ngD.inL.tieGr., IannddustSrtiiee.brMise, cK. .:J.VAaunsatdriaulima, 47:607, 1956. 122. TanhdomCarsit,chMlo.wD,.;J.:HePnrdorliocnkgse,dRe.xHpo.;suGreunonf, gFu.inDe.a; Hpiegaslttoh,s7u7lf:7u0ri,c1a9c5i8d. aerosol. A.M.A. Arch. Indust. 123. iTnimoekmhpinlo,yDm.enI.t: Proofblemmsagonfesiinudmu-sttorriiaulmh-ycgoibeanlet catalyzer, Hig. Truda, 2:42, 1958. 124. T19u5r9,. J.: Liderosis pulmonum. Med. Pracy., 70:33, 125. AV.aMlle.Ae,. BA.rcLh..: IZnidnucsta.nHdeiatslthb,io7l6o:g1i4c7a,l 1s9ig5n7.ificance. 126. Vorobjeva, R. S.: The question of the toxicity of Icmadmmuinuoml. o(xPirdaeg.ueJ). , 121:J24.4,E 1p9id58e.m io l. M icro bio l. 127. Zthaapnpe, Jf.oaAm.: Hplaazsatircds porfodisuocctiyoann.ateAs.Min.Ap. olAyrucrhe. Indust. Health, 75:324, 1957. aPnndeupmnoepuamthoimesycdouseesto organic dusts, allergens 1. CBorihnegnh,urJs.t:, LR.esSp.;iraBtoyrryne, dRis.eaNse., oafndmGusehrsrhooonm2. wBuogrkyei,rsB, .,faarnmderM'sollnunrg, .L.J:ALMun.Age.n, sc7h77d:1e5n, d1u9r5c9h. Reisstrohstaub. Beitr. Silikoseforsch., 57:37, 1958. 3. B70u:g2y0i0,, 1B9.5:8.On Conionmycoses. Prac. lekarstvi, 4. Calhvienoalcarhomtii,crNol.i,thiaansdis aTsasnogcicahteadi, wPi.t:h tPhuelminohnaalray t1i9o5n7. of snuff in Thailand. Dis. Chest, 72:687, 5.' EDxapSeilrviameHnotertlale, J.,KaonrkdstDauebkCoanrivoasleho C(Eanxcpeelrliam, eLn.: telle Suberose) . Arch. Gewerbepath., 75:319, 1957. 6. DGetnrneiedre, Lun.:d PSnaeautmeno.koInnioSsteanubdluunrcgheneSrtkaruabnktuonn gDeanr,mBstaanddt, 139,58e.d.p.b5y41J.tten and Klosterktter. 7. aDnickaiceu,teH.graAn.,uloanmdatoRuasnkininte, rsJt.i:tiaFlarpmneeur'ms olnunitgis, o1c0c69u,rr1in95g8.in agricultural workers. J.A.M.A., 167: 8. cFornanioks,isRd. uCe.: toFaromrgearn'sicludnugs--ts.a Afo.]rm. Roofepnntgeeunmolo., 79:189, 1958. 9. LFaroesgt.,, J7.7,5:a1n3d83,Ge1o9r5g6.. J.: Taerskerlunge. Ugeskr. 10. eGrrsoeatsncheAl,stHhm., aandbrTonrecniaslee, En.:acThodUemingeasnDg rumckit N37a5s,sz1e9r5s8t.ubemitteln. Arch. Gewerbepath., 16: 11. GOxuypgtae,n Aco.nsSu.;mFpteirornis,ofBm. aGle.;Inadnidan Rjuatoe, wMo.rkeNrs.:. A.M.A. Arch. Indust. Health, 20:96, 1959. 12. oKgleunnekseer,deWs .s:ogZeunranFnrategne dBearcherti-oluongdieMunldlerPaasithh- mas. Schweiz, med. Wschr., 57:714, 1957. 13. eKtiyoulnogg,icVal. fAa.c:toDruosft oocfctuhpeatkiounkaklerpsniteeumshoacleonaiossaisn. Gig. Truda, 7:44, 1959. 14. dLioswearsye,"--Ta., syannddroSmcehucmauasne,d Lby. nMit.r:og"eSnilod-iofixlliedre's. J.A.M.A., 162:10%, 1956. 15. M.:urrAayn, oRu.;tbrDeiankgwoafll-Fwoeradvyecre's, Ic.o;uagnhd aLssaoncei,ateRd. 7w4i:t1h05t,am19a5r7in. d seed powder. Brit. J. Indust. Med., 16. ePiensetarlozMzio,dCel.l:scFhreebirnielereiGrduuprpcehnerIknrhaanlkautinognenvoinn mwaitsseSrch(iBmemfeeulpcihlzteernfiekboenrt)a. mScinhiweertiez.mMBede.feWucshchterr., 89:710, 1959. 17. EPoxlpiaekri,mKen.;teGlleiithUerntt,erHsu.,chaunndgeSnchzaunrzenFbraacghe, dHe.:r Gbeehtyregi.d, es7t7a:u5b1l9u,ng1e9.59A. rch. Gewerbepath. Gewer18. aRnodache,nvSi.roAn.m, aenndtalScshtuildliyng,ofR.bySs.siFn.o:siAs cinlinitchael L77a:n1c,as1h9i6r0e. cotton industry. Brit. J. Indust. Med., 19. sSics.hiIllningth, eR.SySm. pFo.:siTumhe oenpidInedmuisotlroigayl Pofulbmyosnsianroy Dp.ise1a8s5e.s, ed. by King and Fletcher. London, 1960, 20. sSics--hilalidnvge,nRtu.re5.aFn.d: mThiseadevpeindteumreio. lJo.gOy cocfupb.yMssiendo., 7:33, 1959. 21. Sertso.ttB, rHit..: JP. uIlnmduosnta.ryMeddis.,ea7s5e:2a3m, o1n9g58st. sisal work 334 MEDICAL PRACTICES 22. Scemnetrtaantiionn, Nof. tIh.:e Tloheess mduaxstiminal thpeermaiirssoibflecocttoonn 23. sTpiilnlenri,ngJ. pRla.:ntAs.nGiingv.esTtriguadtaio,n5:o5f3,by19ss5i9n.osis in a r1a9y5o8.n mill. Trans. Ass. Indust. Med. Off., 7:157, 24. TMootrtaenn,, TR.. JS..:; FRaerimd,erD's. lHun. gS,.;reDpaovrits,oHf .twDo.;caasneds Jin. Mwehdic.,h 2l5u:8n0g3,bi1o9p5s8i.es were performed. Amer. 25. Tinuvfefsntieglal,tioPn. iGn.t,o atnhde aDciuntgewraells-pFiorardtoyrcye, reIa.:ctiAonn Btoritth. eJ.inIhnadluastito. nMoefd.t,am14a:r2i5n0d, s1e9e5d7. preparations. 26. SW:assReercmhaenrcnh, eMs .; eBxupgeeriamg-eMntiahlaeisl, Gco.;nacnedrnalonstub"alsa, Pmraolca.diXeIIdesIntf.ileCuorsngert. dOecscutpis.seHuresaldthe, cHhealusvinrek"i,. 27. W5.3e7g4m, a1n9n5,7.T.; Galletti, P.; and Amrein, H. P.: SBia:u4m37w, o1ll9s5t8a.ublunge. Schweiz. Med. Wschr., 28. ZAanpnrionpio, sDd. e(alnad"FWiavsrseermdeasnnc,erMea.l,esD"isdcuesssitorna)v-: aHlleeaulrtsh, dHeselssiinloksi., 5P:r3o8c6., X19I5I7.Int. Congr. Occup. Inf1e. cDtioraunskiann,dDp. aI.r,aasnitdaiGpenraesuimmoovpaa, tMhi.esM.: Brucello 2. sGisroassn,dP.o;cWcuepsattriiocnk., MGi.g.L.T; rMudcaN,er2n:8e,y,1J9.58M. .; and pPnitetusbmuorcgohn,ioMsi.s. P.A.HM.:.A.ExApercrihm. enIntadlusTt.ubHerecaulltoh-, 3. 1H9a:r3r2i0s,, H19.5J9..: Treatment of Brucellosis. J.A.M.A., 4. J1u7n5:a7k0,9,G1.:960L.eptospireninfektionen bei Kanalar 5. bKeittheren, .J.A: rcDhi.e GLeewpetorsbpeipraotshe., a5ls5:5B6e5r,uf1s9k5r7a.nkheit. Arch. Gewerbepath., 57:316, 1959. 6. mKioncgo,niEo.sisJ..:PRroecc.eXntIIRIenste.arCchonginr. IOnfceccutpiv. eHPeanletuh, 7. HKienlgsi,nkEi,. 5J.:;283Y,og1a9n57a.than, M.; Harrison, C. V.; aPnndeumMoictocnhiiososins,. DA..MA.A.:. EAxrcphe.rimInednutaslt. inHfeecatlitvhe, 8. 5R6a:m38s0a,y,19J5. 7.H., and Pines, A.: Results of treat mcuelonstis.ofBrpint.euMmeodc.onJi.o,si2s:34c5o,m1p9li5c9a.ted by tuber 9. Sskcrhanpkpheeritt, bRei.: MLetuznggeernntuubnedrkubleoisein alLsanBdweriurft 5sc2h:4a1ft7,be19s5c8h.ftigten Personen. Z. rztl. Fortbild., 10. Sbrpuincekl,losWis. inW.h: umCuanrrebnetinsgtsa.tuJs.A.oMf .Ath.,er5a7p2y:69o7f, 11. T19e6r0z.in, A. L.: Psittacosis--ornathosis--mam' mmaamliamnalspneaunmd obniirtdiss. (JP.OHMyPg). Evipriuds.esMiincrombiaonl., Immunol. (Prague) , 2:129, 1958. Lung cancer due to occupation and radiation 1. C19a5u8s.ation of Cancer. British Med. Bull. 14(2), 2. Awsokrk-Urpsm. Dariks., CE.h:eBst,ro2n7c:4h,ia1l9c5a5r.cinoma in printing 3. Afezrhinbgel,frSo.mI.: tOoxniccapnnceeurmdoiascglneorosissesi.n Hpaigti.enTtsrusduaf, 4. 5B:a1r1b,o1r9ik5,9.N. et al.: Carcinoma of the lungs in e5l0e:c4t1r3o,ly1t9ic58.chromium plating. Prac. Lkarstvi, 5. dBiasetrtijberu,tiAo.nMa.n; dDaremteronnti,onC.;oafncdhrBoumdiaucmz, Vin.: mThene a1n95d9.animals. A.M.A. Arch. Indust. Health, 20:136, 6. BBuaedtajcezr,, AB.. AM..:; ELfofewcnteyo,f Jc.hFro.;mSiutemffeeo,nMin.Dci.d; eanncde oInfdluusnt.g Mtuemd.o, r2s0:in124m, i1c9e59a.nd rats. A.M.A. Arch. 7. Bcaindcsetrru. pT,raPn.s. LA.s:s. OIncdcuuspta.tiMoneadl. Ocaffu.,se9s:2,of195l9u.ng 8. LBuonhgliegn,krHe.b,seasndbeJaicodbe,utCsc.:heDnie AHsbuesfitgarkbeeititedrnes. P5:r3o0c8., X19I5I7.Int. Congr. Occup. Health, Helsinki, 9. hBerravuonr,geWru.:feKnredbusrcahn HArasuetn.unDdtscinhn. eMreend.OrWgascnhern.,, 83:870, 1958. 10. dBiraotwionnisn.g,ElEsethveiel:r HMaornmofgurlapehfsfe:ctIsndofusitorniaislinTgoxriac 11. CAgemenbtse.r,AHm.:stBerrdoanmch, o1g9e5n9i.c carcinoma from radio afecrteivnecepaorntictuhleatePse.acSeefcuolndUseUsnoitfedAtNomatiiconEsneCrogny. Geneva, 1958. Paper A/Conf. 15/P/900. 12. CMheiduirccion,a MG.utuAa.:listLicaav,or5o:Veol.t1u4m, o1r9i5.9 A(3r7c2hipvaogesd)i. VHiedlesinaklsio, :14P7r,o(cF.r.X),II139ln, t(.EnCgoln.)g,r1.9O57c.cup. Health, 13. rDealavtiieosn, sDh.ipF.b:eAtwereenvieswmookfintgheanedvidleunncge ocannctehre. 14. JD.oCll,hrRon.:. ODicsc.,up1a1t:i5o7n9a,l19lu60n.g cancer. In the Sym pKoisnigumanodnFIlnedtcuhsetrr.iaLl oPnudlomno,n1a9r6y0,Dpis.ea2s0e8s., ed. by 15. DBroiltl., JR. .I:ndOusctc.uMpaetdio.,na5l6:1lu81n,g19c5a9n.cer: a review. 16. D4(v3i)z:k3o, v1,96P0.. P.: Occupational cancer. Gig. Truda, 17. EancdkarLdot,ndRo.n,E.1:9I5n9d. ustrial Carcinogens. New York 18. Efilellidn,g1e1r1,.,F1.9:57M, epd.ic2a2l4 Rffa. diation Biology. Spring 19. Enisopsiinso. sM-Peedr.ezy, sDeg.:. tCraanbcaejor,p5u:5lm, o19n5a7r. y neumoco20. Finidnkueclt,ioMn.iriParmoc.P.:InItn.teCrnoanlf.emPietatecresfualndUsteusmoorf A19to56m, ipc.E1n6e0r.gy, Geneva, 1955, Vol. 11. New York, 21. Gpaatlhleiegso,duJ.e tDo.:duPstu.lmProonca.rXy IIleIsniotn. sCoinngrp.nOeuccmuop. 22. GHoealdltbhl,atHt,elMsi.nkWi, .5::3O78c,cu1p9a5t7i.onal Carcinogenesis. 23. BGrroits.seM, edH. .B: ullM.,i1sc4h:1s3ta6u, b1i9n5d8u. ration der Hilus6ly7m:2p2h0,kn1o95te6n. und Lungenkrebs. Frankf. Z. Path., 24. BHualdl.d,o1w4,(2A),. 1(e9d58.).: Causation of cancer. Brit. Med. 25. aHnadrrisW, eWin.steBi.n;, BMre.sliSn.,: AE.nvJ.i;roGnmlaeunbtearlmhanaz,arBd.s; aAs.sMoc.Aia.teAdrchw.itIhnduthset. Hmeialllitnhg, 20o:f36u5,ra1n9i5u9m. ore. 26. Hcaunecpereirg,enWes.is.C.X: . Ecaxnpceerriimgeennitcalefsfteucdtsieosf icnhrommetiatel ocarevitryoasotf deraptoss.iteAd.Min.Am. uAscrlceh.tisIsnudeuasnt.d Hpleeaulrtahl, 18:284, 1958. 27. InrimscshcehrerP, nGeu.:moLnieiebernaecihneInnhTaoladteiosfnallvoann alcphhrao- urunndd 2b0etJaashtrraehnle. nDaakstivDeemutsc"hIendGuessturinedshtaeuitbsw" esveonr, 52:1732, 1958. NORWOOD 335 28. WJamaleess, cWoa.l-wR.orLke.:rsPwrimitharpyneluunmgoccoannicoesris.inBrSiot.ut]h. Indust. Med., 12:87, 1955. 29. Kexeongneanwoauys,faEc,,toarsndinLtihnedsceayu,sAat.ioJn.: oSfolmunegpcoasnsicbelre. Brit. Med. Bull., 14:124, 1958. 30. 5K:o12el9s,ch1,61F, .:195D8e. r Arsenkrebs. Zbl. Arbeitsmed., 31. MthecLSayumgpholisni,umA.on1. IGnd.:usItrroinal aPsulamoCnaarcriynoDgiesena.seIsn, 32. ePdu.ccbiyni,KiCn.g: aLned Fplreotbclheemr.aLodneldloan,ca1n9c6r0o,-spil.ic1o6s2i.. Med. Lavoro, .51:18, 1960. 33. BReinruckfs,erkHr.a:nkDunerg. CMherdoimziantiksrcehbes, 3d4e2r, 1L95u6n.ge als 34. ASerpbk.eM, eGd..:, Z7:u1m14,S1c9h5n7e.eberger Lungenkrebs. Zbl. 35. JS.miItnhd, uRst.. AM.:edL.,un7g6:3C1a8n,c1e9r59in. Coal-Miners. Brit. 36. SanudndeKrminacna,idF, . JW. .F; .:DoNninceklelyl , pAo.isJo.n; inWg.estA, .MBo.Ab;. Arch. Indust. Health, 20:36, 1959. 37. JS.u; ndaenrdmaWn,esFt,. WBo.;b:KiNncicakide,l Jp. oFis.;onDinogn.neAll.yM, .AA.. Arch. Indust. Health, 16:480, 1957. TREATMENT OF PLUTONIUM DEPOSITION IN HUMANS WITH DTPA -- EFFECTIVENESS OF LONG-TERM ADMINISTRATION AND ORAL ADMINISTRATION* W . D aggett Norw ood, M.D. Manager, Health Operation, Hanford Atomic Products Operation, operated by General Electric Company for the Atomic Energy Commission Richland, Washington solTuhbele repcloumtomnieunmded(Pmuax2im39u)minpetrhmeishsiubmleaanmbooudnyt oisf 0a.r0e4 nmeciecsrsoacruyriteo--li0m.6it fbigody(1)d.eRpoigsiitdioncotnotrothlismeexthteondts. Fbyorainfsatcatnocreo, falmloiwlliaobnlse tchoanncetnhteratcioomnspainrabalier aarlleowloawbeler cTohnecreentrwaitlilonbseofincmreaansyinogf pooutrenmtiaolst ftoorxiecxpchoesmuriecaltso. isnucihndisuosttorype, sdwefiethnceth, eanexdpmaneddiincginues.eHoefnscuechitmbaetceormiaelss vmeonsitenitmpmoertthanodt topohsasvibelethfeosrafterseta, tbinegst, tahned imndoisvtidcuoanl wwhhoichhaesxcaececdisdetnhteallmyaaxcimquuimredpearmdeispsoibslietiolnimoift. Pu 239 boTrerdeastmmealnlt,quhaenreti,tieosf offivePuem23p9lofyoeressowmheoyehaards ihnadri cmaitneedpetnhtaatacienttircaveacniodusly(DTaPdmA)iniwstaesredmudciehthythleenemtroias-t eufrfiencatirvyeelaigmeinntatdioisncoovfePreud23to9 d(2a)t.e for increasing the ofTthhee perfefescetnivtesnteusdsyowf aDs TmPaAde into eimlimprionvaetinkgnoPwuled2g3e9 rviioad thoef umrianney wmheonnthtrse.atImt ewntasisaelsxotenddireedcteodvertoawapred deleitmerimnaitnioinng otfhePueff2e3c9tivveinaestsheofurDinTePAandin feicnecsrewashienng administered orally. Long-Term Administration of DTPA sitAionn eomfploabyeoeutwh.4o hmaidcroaccucirdieentoafllyPurece2i3v9edsoamdeep3o0 omuoslnyt.hsInpirtieavliloyustlhye wdaasilytreautreidnarwyithouDtpTuPtAofinPtruav2e3n9 wspaesciambeonutof66u5ridniesin(tTegarbalteio1n)s. Ipterwamsincountesidpeerred24a-dhvoiusr pabelreiotdo cuanuletisosuselvyidceonncteinuoef tkreidantmeyenitrroitvaetrioann eoxrteontdheedr untoward effect appeared during the treatment. This D*Tr.heMuDrrTaPyAWfeoirnetrh,isGesitguydyPhwaarsmakcienudtliycalssu,pPp.lOie.dBobxy f4u3l0,inYocnokoerrsd,inNaetiwngYsoarmk.pRle. cHo.lleWctiilosnonawndasamssoissttinhgelipn ptheerfoirnmleetdprethlaetiobnioasosfayrsesoufltst.heG.maDn.yBsraomwpnlesa.nd staff wamouoludntseorfvePuth2e39daunadl ipnudripcaotsiengowf heelitmheirnaotrinngotathfearier wovaesr.aancheaxntgenediend epfefericotidv.eness of this agent when used T able I EAFDFMECINTIISVTEENREESDS DOTFPAINITNRAINVCERNEOAUSSINLYG URINAGRIYVEENXCFROERTIMOANNOYF MPOUN2T3H9 SW HEN TWreeaetmk eonft Doisne--GrDamTPs A Per Week 21 21.6 Nopetrrieoadtmoefnt5 fworeeks 1113--1124 21.6 Nopetrrieoadtmoefn5t wfoereks 2276 22 4336 22 50 2 ADvaerilayge ExUcrreitnioarny of ExpPruess2e3d9 as D iPseinr teMgirnautitoens 666150 48112 495 49165 423466 112950 EExffpercetsivseednesass E%ffeocftiIvneinteiassl 19020 7742 6764 2397 19 preAcveedriangge adnadilyfoellliomwiinnagtiotnheofabPouve23t9reaftomrenpteriwodass 12 disintegrations per minute in 24 hours. emEpxloceypete fwoarsmgiivneonr 1chganogfeDs TasPAshoinwtrnaviennoTuasblyle, iIn, tthhee M1 agnuofnactTuhriunrgsdAayreaofMeeadcihcalweCeekntefor,r otnhreMeonsudcacyesasinvde wpeereikosd.sSoufchthpreeeriowdesekosf otrfeantomternetatwmeernet.alTtehrinsawteads wcoitnh- 610 SOCIAL AND LEGAL ASPECTS wdeomrke.nt above the loss of wages the longer he was off peTrpheistractaessehiilsludsitsraabteislityhoown aansuibnjdeicvtiidvueabl adsiesliibneroartdeelyr to increase Case N o .th3e--sizAe o3f7-hyiesarm-ooldnettarrayinmseattnlemweanst.injured wwhhielne hsitsanadrimngwatosostrculcoksebytoa agraslbowirloyn,mcoavuisnigngtrhaiimn taocsapr.inHaeroreucnediveadnda s5t-rcikme vheisrtihceaaldlaacgeraaintisotnthaecrossidsethoef mmaidindeled oofnhhisis ffoereeth. eTadh.eTlahceermataionnwwaasssrteupnanierdedbautt trhee pTlhaenrte dwisepreensnaoryo. thXe-rraivnsjuorifestheexcsekputllfowr eareslingehgtatciovne. ttuiosnionwaosf enthtiererlyighnteguaptipveer anardmr.emNaeiunreodlogsoic theexraemafitnear. cNaotiotnreaftomrenptaiwn.asTihndeicpaatetidenotthdeirdthnaont awnaolrgkeshicismneedxit otuursn naingdhtwahseseheandagaainmtihlde fhoellaodwaicnhge dabyu.tTwheasprneovwi apsaytimenpttomwaastics.eeEnxaamgaininatifoonurwdaasysagaafitner nethgeatiavcec. idTenhte. aTphpeliesdu.turHesiswoernelyremcoomvepdla,inant dwaadsheoscicvaesiborniadlgefsrownetrael hreetaudrancehde two hwicohrkw; aasndrewliehveend qbuyestaisopnieridn.asHteo hwahdy,nhoet gaarmve asnodmeupvpaegruebaccko.mEpxlaaimntisnaotifonsorweansesasgianinhnisegraitgivhet ftohre ombajenctbiveeliefvienddinhges.coIut ldseeamndedshtooultdhebephwysoirckiainng tbhuatt faoprprsoovmede froearsownorhkadandnotwadsonsoe asod.visHeed. wTahsefopramtiaelnlyt rweoturkrnededfortosevweorarkl hsoiuxrsdbayust tahfetnerretphoerteadccoifdfebnetcaaunsde ocof mhpelaadinacinhge. oHf ehewaadsacsheee,n daizgzaiinnesst,heanfdollsoowreinngessdaoyf, thheealiunpgpewrelbl.acEkxaamndinartiigohnt raesrmult.s Twheere lanceegraattiivoen owncaes atrgeaaitne.dHesymappptaormenattilcyaldlyid annodt inseteennd atgoaiwnorokn;ehewweeaks lloatweirn,gatthwishicvhisittimhee hwisasconndoittiosenenwaasgauinnchfaonrgeadn.oFthoelr two weeks. It was then 24 days since the injury. The wpahtiicehnt hehadhadtakreenceihviesd vvaaccaattiioonn ipnayt.heHeinoteffreimred, fnoor cTohmeplmaiannts,finaanldly threetuerxnaemd intoatiwonorkwa3s0 adgaayisn anfetegratitvheis. liintjiugraytioanndagreaminastinethde actowmopraknyt,hebreecaafutesre. hHee dienmstaitnudteedd ceoarmnpinegnss,ataionnd tahbeocuotmspeavneyn retifmuseesd htoisgraacntut atlhelocslsaimof. peEriaocdh ittimseeemtheisd ptahtaietnthewarseasleleyn bdeulireinvegdthhee 3c0o-dualdy wicoalrlky aanbdle thaantd hewaasctnuoatllycownsaindteerdedtoa.sHheavwinags pphoysst atrpapuemaraetdic tnoeubreossiesv. eWrahl yretahseonns.diWd hhielenothtewpoarkti?enTthweraes bdeeinntg, tareacteodmpinanytheredpisrpeseennsatartyivsehorretlmyaarfkteedr ththeaatcciit wgroouulpd hbaedggooodneiffohreandidunnuostuamlislsenwgothrko, fsitnicmeehwisitwhoourkt atielnotst-atnimdehaisccifdelelnotw. Twhoisrkewrass aisntceorpmrpeatendy binytetrheestpian aRveosiednintmgenlotstwtaims einrcaittheder atnhdan lethde teompdleolyibe'esrawteelfalorest. tbiemcea.usTehhee phaadtieanthewaadsinajlusoryewnchoicuhrargeeqduitroedmsiusstuwrinorgk. Amneontthefiry cfaecrttoairn wphaircthiespltaoyeddeliaberpaatertlywpaesrpeentcraotueraugne ncleaciemssaarygailnosstt ttihmee cfoomr ptahney pfuorrpoisnecoomfeesgtraebaltiesrhinthgana hisThreisguclaasreeialrlnuisntrgast.es how management action, work ginrouwporsktangdroaurdpss fionrtelrofsetretimwei,thantdhelitmigeadtiicoanl pmraacntaicgees mdiesanbtiloitfy tlheeadiinnjgurteodexecmepssliovyeemaonndetcarreyatgeaiunn. necessary Summary facItnorssumthmatarhya,vIe haavneegoautitvlieneindflcueerntcaeinonsoctihoe-edcoisnaobmleidc seumcphloyfaecet.orTsheintdeirsfceursesiownithhasthdeealitndwiivthiduwahly's arnecdovheorwy fcrloemareranuoncdceurpstaatniodninalg inmjuusryt , pwreicthedteheantyhoeufgfohrtt tthoatdoa anything about them. BASIC PRINCIPLES FOR PRECAUTIONARY LABELING E dward J. H ogan Vice-Chairman, Labels and Precautionary Information Committee, Manufacturing Chemists' Association, Inc;; Packaging Coordinator, Allied Chemical Corporation, New York, N. Y. asIta isreparnesehnotnaotirveanodf athepriMvilaenguefactotursipnegakChtoemyiostus,' Aufsascotcuiaritniogn, Crhegemaridsitns'g Aonsseociifatiitosn acistivaitnies.inTcohrepoMrataend n18a0tiocnoaml ptarnaidees eonrggaangeizdatiionn thceommpaonseudfacotfurme oarned thsaalne othfanch9e0mipcearls.cenTthoesfethecocmhpeamniiceasl parcocdouucnttionfocrapmacoirtye ofFtrhoem UintsitefdouSntadtiensg. in 1872, the MCA has been gcoronwcetrhneodf wthiteh cthheemmicaanly ipnrdoubsltermy.s Pacrocmominpeanntyinamg othnge cthiaetsieonhaiss bpereonudthoefpirtosmcootniotrnibuotfiosanfsetyto, atnhed rtehceorAdssoof cthheembiceaslt minanuaflal ctiunrdeursstriyn. thTishirsegaarcdh,iewvehmichenits aismotnhge mofortehenointadbulsetriyn'sviperwoceosfsetsheanindheprreondtuchtasz.ards in many thaTtheofAsistosciamtieomn'bseirns'tereemstplionyeseasfetytogoiensclfuadrebetyhoonsde torbajnescptiovretsinagr,e hparnodmliontge,d ainnd aunsiunmg bietrs opfrowdauycst,s.buTtheI swhiathll tdhiesculasbsealitngthoisf cthimemeicoanlslytothiantstrpuhcatsethocosencherannedd linIgn otrheuseianrgly tdhaeyms ohfowthetoindduostsroy sbaofethly.the chemicals dinistnruibmubteedr aanndd etahceh thraaddesbeuesninlgontgheemstawbleisrheedli.mCituesd tcoommeprosuwndesre tshoatacscpuesctoifmicedintsotrutchteiounsse soefemtheed exuinsntiencg einssdaursyt,riaalndchseumchicalws arwnienreg lliambeitlesd astowetrhee ussterodngoenr HOGAN 611 aocfidcsouarnsde, atlhkeali1e9s,27anFdedeexrtarlemCeaupsotiicsonPso.isTonheArectwaenred, athenseumwbeerre cohfiesftlyatedipreocitseodn toandthephlaabrmelaincgy oafctsh,oubsuet thoowldardpatchkeagheas.zarIdn ofmoinsgt esctaiosens atnhdeyrelwieedresopleoliyntoend the word "POISON" to warn the user. useThoef eitxspapnrsoidounctosf btrhoeuginhdt ursetcryognanitdiontheofbtrhoeadenneeedd fsoterpsmionrethcisomdpirreechteionnsivceamlaebeinlin1g9. 34Onaendofcovtheeredeatrhlye purnoifdourcmt gprroeucpasutiuonndareyr alabseelriinegs ooff vsioxlunptraordyucatsgreoer manedntsthebeStwuregeenonthGeenmeraanlufoafcttuhreerUs noitfedthSestaetesp.roTdhuecstes wagerreeemdiesnctosntsienruveedd bay vtheeryUunsietefudl SptautrepsoPseubulinctiHl etahlethy dSuercvtsicewihnich195h2adb,ecianustehespemceifaicntilmabee,lsbefoenr tdheevseeloppreod purnodgerram thweereMcaonnusfiadcetruerdingmorCe heamppisrtosp' riaAtes.sociation's groAusp,cmheumliitciaplliepdroadnudctsg,rewespmecoiraellycominpletxh,e thoergnaeneidc bfoyr faurstuhrevreystepcosnbdeuccatmede ebvyidetnhte. TAhsissocwiaatsioenmpinhas1iz9e3d6 wofhiachprreinsuteltdedbionokdisttirtliebduti"oAn tCoointsfimdeenmtiablerReexpeocurttivoens AMdaenquufaatceturLearb."elinTgh--isItsreIpmorptortpaenrcsueadtoedthme aCnyhemcoicmal ppraongierasmtsooremtobaerxkpanudpotnhosteheailrreaodwynbewgaurnn.ing label ouWr oinrdldustWrya. rNIoIt ognrelyatldyidacecsetalebrlaistehdedthcoemgpraonwietsh eoxf pthaenyd dtheveeirlopperodduicntniounmeorfabwleell-nkenwowonnecsh. emMicaanlys, cbourt apsorcaotimonpsletferloymneowthecronsceegrmnse,ntbsegoafn incdhuesmtriyca, l asmawneull ofafctvuireew. Aonf dp--remcaousttioimnaproyrtalanbteloinfga--ll,thforuosmandthse opfoiinnt wdiovrikdeurasl bceogmapnantioes,oplaerrgaeteanpdrocsemssaelsl, uasnidngmcilhlieomniscaolsf Tenhteirenlyeefdorfeoirgna tcoomanpyrehoefnsthiveeirpproregvriaomus oefxepderuiceantcieosn. iinn t1h9e44saMfeChAancdolninsgideorfedchtehmeicparlosbwleams oabtviaousm. eEetairnlgy obfestitsmemthemodbetro erxeeaccuhtivtehs.e Imt awnasindetchiededshotphatusitnhge cahnedmitchael pforormduactitosnwaosf bay m"LeaabneslsofanindstrPurcetcioanutiloanbaelrsy, Information Committee" was accordingly authorized. calTlehde, LmAePt IfCoromthmeittfeires,t astimitehaosnsinMceaybe1e7n, p1o9p44u.laTrloy isnesleucrteedainbcrlouaddedvtiehwoseofwitthhe chperombilceaml,, mthedeicmal,emlebgearls, rtehsaetarcdha,tea, dmthiinsisthraastivbe,eeannda sacloesntibnauciknggrouanndds. aScitnivcee icnodmumstrityteea.ndThademiwnoisrtkratoofrs LoAf PhIealisth waenldl skanfeotwynproto gGruamidse tFhorroutghhe iPtsreppaurbaltiicoantioonf "WWaarrnniningg LLaabbeelsls--foAr HfearrzeadrdtoousasCthheem"iLcaAlsP.I" MTahnisualm,"anisuanlo,wfrienqutheentrlyevierew stitoagne,thwisithyeaar. Fifth Revision scheduled for publica neIetd mfoigrhptrebceauatsisounmareyd ltahbaetl,inhga,vitnhge wagrrietiendg uopfonlabtehles wisotuoldmabrek saimhpalzea.rdAoluls opnreodnuecetdPOdoIS, OyNouanwdoualddd stahye, dinovsolvaendd tdhoann'tst.haUt.nfortunately, the problem is more calWs hmaatyabree thhaermmfuealniinngas voafritehtey toefrmwsayuss.eAd? pCrohdemucit wshhoiuchld nmoaty bethlraebaetelend ythoeursamlifee assoloenlye tbhyat imngaeystkioilnl balysoabthseorpmtiaotnterthorioudgehgreteh.e Hskoiwn. sOhafllcowuersed,isttihnegrueisihs wbehtiwcheecnautshees cvyaapnoorsiso?rWgahsatwrheiaclhly aisspahy"xpioaitseosn"a?nTdhoenree ibsuttheaccduifrfaicteu.ltyThoefylamnguusatgeb.e Setaxtpermesesnetds imnustetrmbes btrhiaetf ostradteinmaeryntswhoreklpmeanvouidndaecrsctiadnendt.s, Nboutt oinflysumchusot cctuhre, afinrstinatiedrpsrheoteurl.d Innotthebecadseelayoefdtrwadheil-enasmoemdeocnheemhiucnatlss otor pthroeprdieotcatroyr cwohmopomunayds,bewhaastkeisd otuor trreesaptonpseibrsiolintys injured by them? folAloswainrgesuplrtinocfipthleessewaenrde madanoyptesdim. ilTahr eqsueesptiroinncs,iptlhees aLrAePsIetMfoanrtuhali.n detail in and comprise Part I of the lem1. Eanacdh mchuesmt ibcael tprreoadteudct inpdreivseidnutsallay diinstinthcte plrigohbt ohfaziatrsdsowonf achparroacdtuecritsticcasn.noCtonscalfueslyionbse rdergaawrdningeiththeer ifsrofmormtheed porropbyertaiensaloogfiesthebasmedateurpiaolns cfrhoemmicwalhiscthrucit pturroep.erMtieixstuthreast ovfarytwion okrindmoorre dcehgermeeicafrlosmmathyosheavoef tmhiextuinredsivisdhuoaulldcobme pboanseendts;onantyhewparronpinegrtielsaboefl tfhoer fpirnoispheertdiepsroadnudct.shIomupldurintioets bmeayovceornlotroikbeudte. hazardous bri2e.f,Aallccusrtaattee,maenndts exopnreswseadrniinngsimlapblee,lseassihlyouuldndebre stood terms. an3d. tPoretchaeuteioxnteanryt nlaebceeslisnagry.shTohueld labneguusaegde osnhloyulwdhebne opfraactipcraol,dunctotalobnaes,edbutupdoirnecttehde toiwnhaerdrenthte parvoopideartnicees ostforhagazearadss mreasyultrienagsonfraobmly sbuechanutsicei,pahteadn.dliTngh,e aunsde othfewuasrenionfgulnanbeeclesssfaorry rweloartdivselwyillhadremvleelsosp paroddiusrcetgsarodr ffoairlulraebetlos gainved addeefqeuatatethneoirticpeuropfohseazaarsdss.urely as will gu4a.geOtno ilanbdeiclsatoefthdieffsearmenet hparzoadrudcstsanudnisfaomrme idtyegirneeslaonf huanzdaerrdstainsdimngostthdroeusigrahblestanindarodridzeartiotno. gain greater sid5e.reTdheforfoilnlocwluisnigonsuobnjecat wmaranttienrg slhaboeull:d (ab)e nacomne ohfazaprrdo--duDcAt;NG(bE) Rs!i,gnaWl AwRoNrdINdGe!s,ignaotringCAdeUgTreIeONo!f m(c)eaAsuffriersmactoivveerisntagteamcteinotnsoftohabzeardfos;llo(wd)edproecrauavtiooindaerdy; a(ed)viIsnasbtlreu.ct(iNonOsTEin: cuansedeorfsocomnetalcatwosranextipdoostuesre awreherree qtiuonirsedforwthheenhathnedliwnogrdand"PsOtoIrSaOgeNo"f icsonutsaeidn.e)rsInshstoruulcd aislsoinfboermcaotniosinderreeldatifnogr itnoclcuhsaiorancteornistitchse olfabtehl.e Tcohnis tainer as well as those of its contents.* sku6.llTahned icnrcolsussbioonnesofonthae lwaboerld s"hPoOulIdSObeN"limanitdedthtoe those cases where the product is a poison according 612 SOCIAL AND LEGAL ASPECTS ptoresacrdibeefidnibtey tloaxwi.ciWty hsetnanudsaerdd, othriswlheegreendsuschhouulsde bies innotadtadkietiotnhe toplatchee oofthtehre lwaboerdl swDarAnNinGgsERa!n,dWsAhoRuNld IthNeGr!e, laatnivde CdeAgUreTeIOofNh!,azwarhdi/c)-h are designed to show sh7o.ulAd nnoontdebsecriupsteivde acsodtehedeosinglynatiidoenntoifrictartaidoen noafmea hshaozwarnd,outshechleambeilcals.hoIufldthecleacrolmy psletatete ntahmee tyipse nooft ch8e.mWicaalr--nien.gg., st"aCteomrreonstivs eshAocuildd", be"LgearodupCeodmtpooguenthde"r. pinrinatepdroimn ineaesnitlylolecgaitbiolen toynpethwehilcahbeils ainndcoshnotrualsdt bbye tteyrpoognratphhey,lablaeyl.ouTt,heorlacboellorshwouitlhd obtehearffixperdintfeirdmlmy atto anIdn inacacocrodnasnpciecuowuisthpltahcee opnrintchieplceosntjauisnter.stated the "uDsuAalNGwEaRrn!i"n,g"WlaAbeRl NiInNclGud"e,so:r ("aC) AaU"TsIigOnNal""--wtoorgdi--ve aa sgteanteemrael ntindoifcahtiaoznardof otrhehaszeavredrsi--tysuocfh haaszar"dV;ap(ob)r AExbtsroermbeedly THhraozuargdhouSsk",in""C; a(uc)sespreBcuaruntsio,"naoryr "mReaapsuidrelys --hesautchanads o"Dpeon nfoltamber,e"atohre "vAapvoorid," c"oKneteapct awwaityh fsrokmin ainndcaseeyeosf";acacnidden(td,)a,s w"hInerecasaepopfrocporniatatect, iimnsmtreudcitaitoenlys faltutsehntsioknin."or eyes for 15 minutes; for eyes get medical maUysirnegad:these or similar statements, a typical label DANGER! HAZAARNDILOIUNSE LIQUID AND VAPOR RAPIDLY ASKBISNORBED THROUGH ADvooindotbgreeatthiningeyevsa,poonr. skin, on clothing. UInsecoansely owf itchonatdaecqt,uaitme mveedntiialtaetliyon.remove all cflounshtamskiinnatoerd eycelosthwinitgh, pilnecnltuydionfgwsahtoeersf,oranadt clelaostht in15g mbienfuotrees;reg-eutsem. edical attention. Wash POISON t*iAonuthhoars's Naovateil:abTlhee aMtanitusfacotfufircien,g 1C8h2e5miCstos'nAnesscoticciuat Asevreiensueo,f Ni.nWdi.v, idWuaaslhiCnghteomnic9a,l DS.aCf.e,tyat DnaotmainSahleectosst,ona tlhinegparonpderutisees oafnd19escsheenmtiaiclailns,foMrmaantuioanls foonr sSatfaenhdaanrdds oafndspReceicfiocmcmonetnadinedersP,raacntdiceasn oonuttlhineeuosef raencdomhmanednldinedg gtaeinnercallaspsersecoafutcioonnstaifnoerrshainndtlhinegMaCnAd sLtAorPa1geMoafnucaerl. oTphmeseentdaotaf awpipllliscearbvlee apsheraxcseesllefnotr gcuoidnetasininerthheanddelvinelg and storage statements. finAduisthcroirm'sinNaotetley: iTnhtehewpoarsdt,"aPnOdISitOs Nm"eahnaisngbeheans bueseend rilelcodgenfiizneesd.poFiosornlianbgeslinbgy pthurrepeosemsodthese oMfCeAntrMy--anvuiza.l, ibnugtesltiimonit,s inuhsealaotfiotnh,e awnodrdabtosortphtoisoen ctahsreosuwghhersekinth--e ptoexriicenitcye hoars lbaebeonratdoermyoannsitmraatlesd,teestisth, etro beyxceheudmacenrtaeixn defined limits. huPnadrrtesdIIilalnudstrIaItIivoef tlhaebeLlsAPsuIcMh aansuatlhceonotnaien ssheovwernal. aTmhopslees iinnclPuadretd IaIreagreeneforarllyindfoursttrhiaolse cphreomdiuccatlss. mEoxst iambprooratdanrtancgoemomferhcaizaallryd,s.anTdh,easlabaewlshionleP, athrteyIIItakcoevienr sthecetiomnajwoaristyadodfedpefsotilcloidweisngsotlhde ipnaslsaarggee ovfotlhuemeF.edTehraisl TInhseectliactitdeer, rFeuqnugiriecsidea,deaqnudateRowdaernntiicnigdelaAbeclts ifnor19th47is. ihmavpeortthaentingfroorumpalofapcphroemvailcaolsf, tahnedUtnhietedMSCtAateslabDeels pInatretmrpernettatoiofnA1g8r,icRueltvuisreionan1d. are consistent with its expHeocwteds,ucthceessLfuAlPIisptrhinecipLlAesPIhaPvreogthraemb?roAasd msuapypobret o90f MpeCrA cemnetmobferst,hewhUo,.S.aspsrotadteudctioenarlioefr, irnedpurestsreinatl cahnedmiocualts. oIfn thfaect,Ascshoecmiaitcioaln, mfaunlluyfacstuupreprosr,tebdotthhesine panridnciisplessu.ppTohretedveeryxerftasctathpaetrsusuacsihvea foprrcoegraumponexitshtes mlabaenluinfagc.tuTrheer lwathtoer mknigohwts oththaet,rwsihsoeuldneghleectbe pcraolpleedr itnoadceoquurat teblyecaluasbeeleodf pcrlaoidmuecdts, inthjueryopbpyosionnge coofunsheisl swimouilldar scuormelpyetictiivtee pthroeduwctasr.ning statement used on CoWmimthititneemionnth19s44a,fteitrs tchheaiormrgaannizwaatisonasokfedthteo LseArPveI saesquaednvtilsyorbetcoamtehetheStfaitrest ooff sCevaelirfaolrnsitaat,eswtohicrehgusluabte BtheesidpersecCaaultiifoonrnariay, tlhabeeleinngsuinogf yheaazrasrdhoauvse csheeemn icsaimls. iOlarergorne,guHlaatiwonaisi, oIrllinloawiss, Taedxoapst,edNebwy JCerosnenye,ctNiceuwt, Yupoorkn SthtaeteMaCnAd NpreinwciYploersk. City. All have been based InsReecftiecriednec,e Fhuansgicaildreea,dyandbeeRnodmenatdiecidteo Athcte, Faneddertaol ttihoensfaiscstuetdhapt uLrsAuPanIt latobeilts. comply with the regula heAldt mineeGtinengesvoaf, thSewiItnzeterlrannadt,ionthael LMabCoAr'sOrpgraenciazuattiioonn, acoryntelanbt ealidnogptesydstfeomr uwltaismaetnedoursseedbyaInLdO mouncha woforlidts wiAde cboasmism. ittee of the International Association of aGnodveCrnamnaenditaaln Lsatabtoer, Oprfofivciinalcsi,alw, haicnhd cfoendseirsatsl oafdmUi.nS. ifsotrrmatoRrsu,lehsasanddevReleogpueldatiaon"sSureglgaetsintegd toDrtahfet fLoarbeUlinnig finogr USuseb,staHnacnedsliHnga,rmafnudl StotorthageeSoaffetCyoanntadineHrsealHtholodf Eanmdplowyaesest.h"e Tfhoiusnddartaioftn afdohrertehse tcourLreAnPt I repgruinlactiipolness in New Jersey and New York State and City. indInusttrhyispahritgichulylarrleyg,ualaretedsubejreac--tewd hteon maallnyofresutsr,icatinvde ilcaawlsinadnudstrreyguthlaattiointss--aditeqiusattoe tlhabeelcirnegdiptraocftitchees cbheegman alastioanvoolfunrteacryentpryoegarrasmhaasndbethenat itnhesulpabpeolritngoflegthise indFuusrttrhye'sr pervinidceipnlcees roafthethrethLanAPcIonCtroomvemrtiitntege'stheimn. fsltuaennticaellyis tihdeenftaicctalthawtitdhefitnhiatitonosffoirts"PmOaISnOuaNl " wsuebre swercittitceinde inAtcot athned rheagvuelatailosnos buenendersubthsetituFteedderianl tIhne KLEIN 613 fIonrtmerestratdeefCinoimtiomnerocfe "CColamsms iBss.ioPnoiRsoengsu."latAiognasin,foLr AthPeI ohfasthbeeewn oridnst"rfulmamenmtaabl lei"n boybtIaCinCingandtheothaecrcepptuabnlciec "aignefnlacmiesmaabsle.l"essItslikreelpyutatotionbe hamsisuexntdeenrdsteododsothfaanr tMhaatnufinactu1r9e5r3s, twhehicAhssiosciMatiCoAn'sofBriBtirsihtishcouCnhteermpiacratl, sthenetLrAePprIepsernotgartaivmesantdo stuhbisseqcuoeunntltyryadsoolpetleyd toonestpuadry allTelhinisg pitr.ogram is receiving additional impetus from oouthserintratdheeirasscoocoiapteiorantsi,onw. hiAcsh ahlarveeadbyeeinndmicoasttedg,entehre cLhAemPIicaolsb.jeWctihviele istheprpinricnicpiapllleys aarime egdeneartalliyndaucscterpiatl adbelteailtoforalldigffreoruepnst, stehgemirenatsp.pliAcatcioonmmmitatyee voarfy thine Cprheepmariceadl aSpmeocdiaelltielsawMfaonrutfhaectulraebreslinAgssoofcihaotiuosnehhoalds padroddituicotns. toDisrmecatlilonhsoufsoerhouslde paraeckuagsuesallayndanmiamypcoorntvaenyt pinrfeocramutaitoinoanryfosrtatpermoepnetrs. uSsiemiwlahrliych, thsuepAplmemereicnatsn tPhee ctraoulteiuomnarIynsltaitbuetles rfeocrenptleytropluebulmishepdroadumctasnuaasl doifstpinrcet pfrroinmcippleetsr.ochemicals. Both associations support I,API anTdheunciofmormmonlaabimelinogf alolfthtehsee ghroazuaprsdoisusthesuabdsetqanucaetes wfreheichflotwheyofprcoodmumcee.rcUe naifnodrmiimtypoisrtaenstsenintialedfuocratitnhge pinegosp.leThteo puunbdleicrsmtanudst btheelesdigntoifirceacnocgeniozfe ltahbaetl cwheamrni cqaulirperocdaurcetsinmahya,nodnlinogc,cajsuiosnt , abse ehxapzearrideonucse atnedachrees utosolsthaatndcarwe ithin ehlaecntdrilcinalg aisndnecmeesscahraynicwailthdeevdicgeesd. Uchnelmikiecaltshe wlailtltera, lwwahyisch rseeqlduoirme csaormrye wparrencinagutiloanbaelrsy, mlabineelidngb,ybevciasuusael tihnespirecptrioonp.erties can seldom be deter preIncauctoinocnlaursyionla,bIelisnhgoupldroglirkaemtobaesemdphuapsoizne tthheatprainny cciipalteiosnsectofuolrdthnboyt tbhee McoannsiudfearcetdurienxgpeCrihmemenitsat'ls. ATsshoe ctiomnec-epprtovoennwahnicdh ascuccehptaedpriongrsaimmilwaars pbraosgerdamhsasinbeteern ntaaktieonnaolluyt. iWnsuitrhanscuechona tphreogfruatmureyoouf yhoavuer pnrootduocntlsy, bfuuntdaymouenthaalveoblpirgoavtiiodnedtoawnaercnesosfartyheadhjeuanltcht hianzatrhdes pinrvoodluvcetds. in the use of either new or established I thank you! THE CARDIAC CASE IN WORKMEN'S COMPENSATION I rvin K l e in , M.D. Medical Director, Workmen's Compensation Board, State of New York thiIrtteiesntmhy Ignrteeartnaptlieoansaulre Ctoongbreesasbleonto Oacdcdurpesastiotnhaisl Hnoeanltahti.oIntalisbosiugnndifairciaenst, tahnadt tcoogmetmhoern wperobhlaevmessokungohwt r3e0myeedaierss. iInt disiffaeprepnatrecnotunthtraiet sthoifs tihse thweoroldnlyforsoouvnedr mofetahdodditiboynawl hsicighniwfiecanccaen tshoalvte wtheesaereprtohbulesmasb. leIt tios mseat ttearsgmooady ebxeamdipspleoseodf otfh. e way in which other casTehiisn wafoterrknmoeonn's wcoemapreensattoionc.onTsoidemr ertehley cdaisrmdiiascs ittalewnitthantdhe inwteavnetioonf othfethhisanodrgiasniuznatwioonr.thyA osfeatrhche ainntdo itmhepocratuansets. Tanhdereresiusltsa icnontthiinsuianrgeaanisd ngecroewssianryg iinntetrheestcoiunrsethoef ecmarpdliooyvmasecnutl.arReecpenistolydegsredaut rainttgentaionnd hcaassesbweehnichpahiadvetocomthee beinfocrreeasthinegwnorukmmbeenr's ocfomthpeesne sNaetiwonYobrokarSdtsatefoforr ethvealuyaetairosn19a4n7dtoad19ju57dicthateiofnig.urIens hthaevefirrsitsesnix mfroomnths16o7f c1o96m0puenpsatoted150cacsaessestowe5re45c.loFseodr wwiitthhdoruatwaawl aorfdcflaoirmm, aannyd rfeaailsuornes t(ofamilaukree otoutpraospercoupteer, cbaeseen atfhteer ctoriraoln).arTy haertemroiesst rferesquulteinngt iinnvoplvoestmocecnltushivaes anIgtinias, nfaoitlunree,cepsusalsrey iarrtegthuilsarittiimese, atondreivnifeawrctitohne. var iiosuist snkeicllesssianrvyoltvoedreviniewthethediangeneodstifcorprporcoepdeurrehsi,stnooryr and record keeping. We can safely assume that the tthraeisnee. dThpehreysirceimanainiss, thfuelrleyforaew, aornelyotfhethceonsniedeedratifoonr owfortkheloraedlatainodnshthipe opfrotpheer praethhaobloilgitiactiopnrocoefssthtoe pthae itnientth.eItcliosssuurgegeosftead cthoarotntahrey evxeascstelmaencdhanthices riensvuolltvaendt mmyuostcabrdeialfuritnhfearrctcioonncedaered nthoatt ftuhlely sculnerdoetrisctopordo.cesIst bpelagyisnsafaliarrlgyeeapralryt iinn atdhueltolcicfeurarenndcethiisn, iunndduosutrbyt.edly, is Iht irheads bfoerenhitsheabpilhiitlioessopahloyngthawtiththealwl oorfkinhgis mdaisn ianbciluimtiebse,nwt hueptohner thmeanpihfeyssticioarn htioddbeen.thIet ifsirstthetorefroerce oogfnitzheis thasis winell.inIdtusatrpyp.eaOrsthetors msehouthldat bneo codgenfeiznasnest caanny bdeegsereteupofonscltehreostihsotuhgehtcltihnaictailn eandgivreensuclatsewwouitlhd hthaivse tyopcecuorrfedreainsonaninyg elveeandts. Wnoewhmeruesst, rseicnocgenigzeenethraalt itzoatbioenpsrehpaavreed ltiottlteakevaaluneatitnitudtheiswhairceha.apIpt eairss rbeeast seoanchablceasteo oonrdiintsaryowannalmyseirsitsa.ndRebceogrneiatdioyn totharetviewwe dporecnloutdheauvse afrofmull derxapwlainngatiaoncoantcltuhsiisonti.me should not proIctesiss iims ptohretandtomtoinaknetep faicntormiwndhenthatthethecarldegiaacl bcaesceominesinidnuvsotlrvyedis idniscauscsaesde. Ttoooaofptoenintthebepyhoynsdicihains mofedanicaaldvsopchaetree.inAtthethpartocpeoeidnitnghsefoarttwaihnischthhee isstantuost trained, for which he is obviously ill prepared and 988 MAXIMUM ALLOWABLE CONCENTRATIONS dinailystawtionrgk wMitAhoCuteiinthteerrv)alspe(rwfohricmhinagre pnhoytscicoanlsidweorerdk w(ohric1h0:1r;eqluoiwreesr avvoeluramgee cmoiunludtebelucnognsvidoeluremde oonfly12fo:1r ewnatsireelvyidesnetdetnhtaatrya wwoorrkk)m. anFroambsortbhsis3.4caglcu(loartio2n.8 gi)t o85f0trmicghl(o7r0e0thymlge)neofintricehiglohrtacheotiucrsa,cidmoadnidfiesintiot 1in89to7 mgIt(1is41d2iffmicgu)ltoftotrsiacyhlohroewthagnreoal.t is the pharmacologic edfufeecttooftdhaeilyfacatdmthiantistirtatdiooens onfo3t gococfutrricinhlosruecthhydleonsees, iisntemreeddicpalerpraccatsiece.inIn tchaesespasotfyeaarnsgi1naml pweacstoardismionr nBeeuforarleghiaandn,.throigweemveinr,i,wefocuarn tsiumpepsosea adhayypnmoatixcimefufemc.t emsepdeciaiaryllypriof dwuectlaiknethinetomectoanbsoidliesrmatioofntrtihcahtlotrheethyinletenre icshlochrelothryallhenyedractoer.reTsphoendass,cearctcaoinrdeidngdatoilythdeosAemoefrictarin tMheACc,utrore4n.t3 ghyopfnochtiocradlhoysedraitse.1I-2t isg,waenlldkniot wins tahlsaot kvneroywnrartehaatndchirsonsiicmiilnatroxtoicacthioronniwc itihntocxhilcoartailoniswnitoht tricIthloisreathlsyolepnoes.sible to see to the effect of trichlor eetthhaynleonle, wanhdic,hinisouthr eoppirniinocnip, aitl ismpertiamboarliitley orefsptroicnhsilbolre tfhoart thpehasrmymacpotolomgsicolfitienrtaotxuirceatdioone.s Onowtinogftetno mtheentfiaocnt Nthaisrcosusibsstiasncaet,tawineedcanbycotmhipsarseubitstawnicthe tarfitberroma edthoasenool.f 3fo.5r-m5.s6 1g.9ign oaf mtraicnhlworeeitghhainnogl 7d0aiklyg.. In our case there thaIt ththinekAtmhaertictahneseMAcoCnsiisderraatthioenrstoroesuhlitghi.n Itfhiet fwaacst ctoreadteecdlafrreomthaetxpaenriimmaelnstsarweithnoatnismuiatlasb, leit iins ntercicehsslaorry- eluthnyglsenaendcahseasvebeecnatuisreelythedyiffhearveentgwreaayts doefsamtuertaatbioolnizs inbgy tricThhleoredtohsyelenreeq. uired by Swedish authors, 50 mg of otrniclyhlotoractheeticSoavciiedt MinAuCr--inteh,atcoisrr,e9sppopnmds atbheoourtet5i0c.ally ereFdromonloyurtripcrhelvoiroaucsetiecxpaecriidmeinnts,smwahlleerre pweercecnotnasgide, o1f6 tpreicrhlcoernetthwylaesnefouinndaitrha(tupintolowabeoructon40ce0ntjrragtiopnesr laicteidr--inthamtg itso, t7r5ichploprmet)hytlhenee riantiojugoifn t1ricIholofraaciertiics ianbgoucto1n:c2e.nTtrhaitsionratioof wtraischdleocrreetahsyilnegnew. itShevtehrealinocbresaesr voautriornescefnrot mexpprearcimticeentsberaersuwltistnetshsattothtehisratfiaoct.isFrtohme othreatticiatlliys n1o:1t p(oSsosuibielek-VtolagcihvoevAm,orBeaarctocnuiriaetke).dirIectthioinnks fporarcptircaaclticwe,ordkueantdo tthheusgrweaet cdainfficcuolnticelsudoeccuthrraitngthiins ratOion ltihese wbaisthisinofthleitermateunrteiondeadta vtahluaets a 1:g1reaotr p1a:r2t. oaflowngo-rtkimineg wpoerokplaet 5h0avmeg ohrea1l0th0 mdgisotufrbtrainchcelosracaeftteicr aspciodndinwiutrhine100petroJl2it0e0r jiwgeosfeetritchhalot reitthywloenueld incorarier. Tofhitsriccholnocreenthtraantoiolnininuariinrec.orresponds with 100-200 ^g vaFluoers tihnethpeurmpoosset iomfpsoorltvainntginthdeustqruiaelstpioonisoonfs MthAerCe omuagdhet otbosebrveatiaovnasilaibnlepraactgicreea. tItnuismablesor noefcecsasraerfyulltyo imnveteasbtioglaistem,,inanldabeolriamtoinryatieoxnpeorifmtehnetsse, sthuebstaabnscoersp.tiFoonr, macetudaicllayl tahbisnokribnegd idt osies. aEccxeppetraimbleentsto wciothnsidaenrimtahles adruecesduitcahbelmeicoanllysufbosrtanthcees.orientation of newly intro SCIENTIFIC BASIS FOR THE ESTABLISHMENT OF TOLERABLE LIMITS ADOPTED IN THE UNITED STATES FOR THE PRINCIPAL INDUSTRIAL TOXINS Ch a rles R. W illia m s, P h .D. Assistant Vice President, Liberty Mutual Insurance Company, Boston, Massachusetts limInits)thfeorUinnihteadlatSiotantesa,rehydgeievneilcopsetdanfdoarrdtshe(topluerrpaobslee etonxciec tmo aatecrcieaplst.abTlehuvsaluwees ffionrd esxupcohsutreersmstoaspo"tMenatixail soufrepsrotvoidtionxgicgmuiadteesriatols bine iunsdeudstfroyr. cTohnetsreollgiunigdeesxparoe mthuembrAoaldloewstabulesagCe;on"cMenatxraimtioanl ,"AcwcehpictahblceerCtaoinnlcyenthraas mdeapteenridaelsntthoenrethearebasleicveplshiloofsoepxhpyostuhreat wfohricmhocstansucbhe Stiotann,"darwdhsichAsshoasciabtieoenn Zu3ti7lizeCdombmy itttheee A(1m);eriacnand ttioolnersatteod thwiisthpohuitloasdovpehryseaereffetcht.osTehwe hpicrihncaiprealapexpclieepd "ATmherreischaonld CLonimfeirtencVealuoesf," GwohviecrhnmiesntaulsedIndbuystrtihael tkonocwanrcionfogtheenipcroacnedssessenofsitciazricnignomgeantiecriitaylsa. nSdoselintstlietizais iHmypgliiecnaitsitosn--(2)n.aAmlellyo,f tthheaste thteersmes vhaaluveesthaeresaamlleowbaabsliec ktinoonwnthactartchineogteenndicenacnydissetnositcizoinnsgidemr attehraitalslevsehlosulodf ofirneaclcinepetabbeltewoeernthtaotxitchearnedisnoanltiomxiict.wAhsicah mdeantotetersoaf btheenk,epist taos dcelvoeseloptoinzfeorromaatsiopnoswsihbilceh. Tcahne pprorovbidleema, fcaocntn, otthaetiounses.rs Tofhethepsreobtelermms risareolnyeacocfepstemthaentiimcsp.lieIdn vwahliidch bcaasnis bfeortoleesrtaatbeldishiningthelevineldsusotfriatloxeincvimroantmereianlts. A19n4n9uathl e CCoonmgrmesistteoenonOcCchuepmatiicoanlalAgHenetasltaht t(hUeni9tethd TERMINOLOGY Swtaastesm) urcehcommmoreenddeedsctrhipattivteheoftetrhme "aHcytugailenuictilGizuaitdioen" In order to avoid confusion it must be pointed out that there are differences in terminology with refer oInfduthsetrianlumHbyegrsie.neIn ASsseopcteiamtiboenr, b1e9g5a5n, pthuebliAshminegricaitns WILLIAMS 989 m"HenygdieednicMGaxuiimdeumSerAietsm" osupshinegric thCe ontecremntra"tiRoencom(8 h"Houyrgsi)e.n"icInSta1n9d5a6rdsSmfoyrthDa(i3l)y Ipnrohpaolasteidon.t"heForusseomoef tainmcee thoef wtrhieter c(o4)ncheapst beoefn u"Hrgyinggienthice gSetnaenrdalaradc"cepotr "mHoyregieanciccuraGteuliydet,h"e saicntcueal thpeusreposteermofs theexparepspslicmatuiochn of such criteria in the occupational health field. ORGANIZATIONS guIidnestheis Ucnaritreiedd Sotantesbythegroesutpasbliosfhmceonmt poeftenhtygiienndiic vuitdiluizailnsg oapvearialtaibnlge wteicthhninicael xiisntfionrgmaotrigoann.izTathioensAmanerd riceapnreseSntatinndgarAdsmeAriscsaonciaitniodnu,stray, phraisvabtee-enorsgpaonnizsoatriionng dfieevldelospinmceent19o4f1,stcahnidefalrydsthirnoutghhe oitcscuZp3a7tioCnoaml mheitatelteh. Tpuhrepsoese"Aamserwicealnl Sastangdeanredrsa"l inpchlyusdiceal-tchheemscicoaple aanndd atonxdicspamroppleinrtgiesa,n"dMaanxailmytailcaAl cmceeptthaobdles Canodncerenfterraetniocnes,". Sliisnhceed,thaenidr stthaert C1o9msmucithteestaisndcaordnstinhuaivneg btoeenbepuebx tCreommemlyitteaectivoepeirnatetsheisfiseeldt . fTorhthe binasistheoninwtrhoidcuhcttohriys sfotalltoewmse:nt provided with all of their standards, as "CTohnecenMtreaatnioinng" o(f1)Maximal Acceptable levIetlsisofgecnoenraclelnytrarteicoongnoizfedatmthoastphtehreicre coarne wtaimthionuant tskntoowwnhicilhl aeffpeecrtssonormdaiyscboemfeoxrpt.oseInd vuinecwonotafmtihneateidmpariarctiincambiolistty inodfusmtraiianltaeinnvinirg oabnlmeenctosn, cietntirsatinoencsessoafryattmo oespsthaebrliicsh coacnctaempt Tinhaenstes econncoceunnttrearteiodnsininindthuesmtrisaellveospedraotionnost. rreepprreesseenntt tahesccaolneceonftrarteiloantisveof tocxoinctiatym;intahnetys ebxeploewrienwcheidchbyilalnyefbfeucttshyapreersuunscliekpetliybletoindbie vidTuhaelss.e concentrations are usually based ufoplolonwidnagtaproobcteadiunreeds: by one or more of the ((12)) LLaabboorraattoorryy tteessttss uonsinagnimhuamlsan subjects (3) Etinovnsiroinnmpelnantatls and medical investiga thaAt ctohmemeoxnpefreiamtuernetalof exthpeosseurperocsehdalulrescoirs rsehsopuoldndb,etotakthene innotormcaolnswidoerrkatiopnattaelsrno.inThthies atipopnlicvaatliuoens. of maximal acceptable concentra meTnhtreoef tchreitseericaonhcaevnetrgaotivoenrsn:ed the establish ((12)) FOurngcatniiocnaolr ortehaecrtiotinsssuewchhiacnhgeshave no dbiustcecrnauibslee iumnptaoiwrmaredntse,ffescutcsh onas hiena-cltoh oacrdciidneantitosns and increased proneness to I(3n) tDhiossceomcafsoerst oinr wadhviecrhsethseenscoornyceenfftreacttisons hchaavnegebse,enit eisstalbolgiischaeldtoonastshuembeastihsatofreopregaatneidc exposure to concentrations significantly in eaxbclyesswoofuldthepraocdcuecpetabinlejurcyo.ncWenhterantiothne plreovbel htiaosnableecnhaensgtaebloisrheddiscoonmftohret, biatsisis olfogaicaful ntco gasresuatmlye etxhcaetedeinxgpotshuereacctoeptcaobnlceecnotrnactieonntrsatinoont wHoenuclde nitotispriomdpuocretamnat tetoriaullnydienrjsutarinodustheeffeccrtsi. taebrliea cuopnocnentwrahtiicohn ahnays bsuecehn mesataxbilmisahleda.ccept ceTnthroatuiognh tishetopumrpionsime iozef thheealatchcehpatzaabrldes,coints iemngmineedeiaritnegusperoicsedfourregsuitdoanpcreevienntesotabbjelicsthiionng atebrliealscofnrocmentrbaetiinognsproefsetnotxiicn othrenaoixriooufswmorak apnlaaclyess.es Cwoimthpartihsoosne coofnctehnetratrieosnusltsindoficataeisr aecxcteenptt,ablaendconudrigtieonncsy orofothcoernwtriosle tmheeasnuereeds,. Sbyamcpolminpgetaenndt panearslyosninseslhouusilndg baencaarcrcieepdtaobulet mofetehxopdoswurhei.ch will provide a reliable measure coAncirenatnraatliyosness ionf csouncjhuncattimonoswphitehricaccceopnttaabmle itinoannstssearsveareasenacmouenatseurreed oifn eixnpdoussutrriea--l noopteraas aDimagenaonssesosfhdoiualgdnobseisboasfedococnupaaticoonnasliddeirsaetaiosen. pohfyaslilcaflacetxoarsmiinnactliuodninags rweeslulltass ooff acliirnaicnaallyasnesd, mtheeanbsodoyf, asasnedssinag kanmoowulendtsgeofofmatotexriicaollsogiinc effIencts tohfe thaeppmliactaetriioanls ionf qutheestiosnta.ndards, it sho(1u)ldThbee kaecpcet pitnabmleincdontcheant:trations serve as (2) Tsthaenydarsdersveofagsooedngpinraecetriicneg. guides. De staiginninagnd aollpercaotinocnensthraotuioldnsaimbelaotwmatihne (3) Tachceeyptsahboleuldmabxeimapupmli.ed and interpreted buyndecrosmtapnedtienngt oinfdtihveidubaalssis wainthd laimfiutall stitoannsdaorfdthheasinbfeoernmadteiovnelofproemd. which the (4) Ictonissidaedrevdisedto thbaet gtuhiedsees sttoawndaarrddsgoaorde ainsdluesgtarliarlehqyugirieemneenatns.d are not intended (5) Tpohseurelevteols aaresinagpleplicsaubblsetanocnel.y Itno tehxe mcaasey obfe einxcproesausreed toor mdeicxrteuarseesd,, tahnedefcfoenct striotulsatisohno.uld be based on the specific triTalheHyAgmieenriisctsanbeCgoannfeirtesncweorokf inGotvheernsmtaenndtaarldsInfdiuelsd iwnith194v7a.luTehse,ywphuicbhlisthheaynncuaalllly"tharleissht oolfd thliemmitsa.t"eriTahlse, vcoalmuemsitwteheichof aqreuagliifvieend reexppreerstesntinthetheconoccecnuspuastioofnaal dhaetaeltheacfhieldy.eaTr.heTyhearme orsetvrieewceendt panudblisbhroeduglhistt udpatetdo t1o9x5i9c (d2u) sctso,ntfauimnsesv, aaluneds mfoirsts1;6911gamseisnearnadl dvuasptosr;s;an7d1 aphilliosstopohfy 2o1f stho-iscalgleroduptenistatsievte fovrathlueisn. pTahreagrbaapshics preceding its listing of values; "Threshold Limit Values for 1959" (2) inTthhreeschoonldtrollimoiftsheshaoltuhldhabzearudssedanads sghuoiduelds 990 MAXIMUM ALLOWABLE CONCENTRATIONS annodt dbaengreergoaurdsecdonacsenftirnaetiolnins.esThbeeytwreeepnresseanfet cnoenardliytioanlls wuonrkdeerrs mwahyichbe irtepiesatbeedlliyeveexdpotsheadt, dvaaylueasftleisrteddayr,efewritthoouttimaedvweersigehteefdfecat.veTrahgee caomnocuennttrabtiyonwshifcohr athenseormfigalurewsormk-adyayb.eTehxe cheeeadltehd dfoerpesnhdosrtuppoenriodas nwuimthboeurt oinf jufrayctotros swuhchethears vtehrye hniagthureconocfentthraetioncosnteavmeninafnot,r swhhoerttherpetrhieodesffepctrsodaurececuamcuultaetivpe,oitshoeninfrge, qanudencthye wdiuthratwiohnichofhsiugchh cpoenrcioednst.raAtilolnms uosctcubre, dtaekceisnioninatos tocownshidetehreatrioan hainzardaroruivsinsgituaattiona etoxisttsh.e Spaepcpilailcactioonnsidoefrattihoenseshvoaulludesbeingivthene ebvealausastoicoinateodf wthieth heexapltohsuhreazatordscowmhbiicnhatimoanys ofTthwroeshoroldmolirmeitssubasrteanbcaesse.d on the best avail afrbolme inefxopremriamtieonntalfrosmtudiinesd,usatrnida,l ewxhpeenrienpcoes, sviablluee,sfraorme baasceodmobninavtairoinousofctrhiteeritawoo. fTthoexsiec esfhfoeuctlsd onrotobne musaerdkeads adcisocmommfoonrt;detnhoums,intahteoyr othfetosxoilceityc,rinteorriosnhoiunld ptrhoevyinbge ocrondsiisdperroevdinags diaTghneosseis liomf itssusapreecteindteoncdceudpaftoiornaulsediisneastehse. efimelpdloyoefd inbdyusptreiraslonhsygtireanineedanidn sthhoisuldfielbde. Tfichaetyionarefornoutsei,ntienndtehde feovraluusaet,ioonr ofrorcomnotrdoil onfuiscaonmcems.unity air pollution or air-pollution CoTmhmesiettevealounes TahreresrhevoiledweLdimaintsnufaolrlychbayngtehse, rbeevciosmioenss, aovrailaadbdleit.ioTnsheasCfoumrtmheitrteienfowremlcaotmioens tthhee sluisgtgeasntidon aolsfosucbosmtamnceensts,torebfeereandcdeesd, otor reports of experience with these materials. IndInustaridadlitiHoyngietone thAessseocitawtioon grhoaus,pss,incthee 19A5m5,erbiceaenn phuavbelishbienegn thpeubHliysghieednicfoGrui9d7e Sseurbiessta.nTceos.daItne gmuiadneys roefspSemctysththiins hseisriersepiosrtsimtoilathretoA.tIh.He.Are.coinmmApenridlat1i9o5n6s. Ithneforrmecaotimonmeinsdpedrovmidaexdimfourmeaacthmomsaptheerriaicl rceolantcievnetrtao tthioenss;hsoervt-eerxitpyosoufrethetolhearaznacrdes; (abtmotohsphheearlitch caonndcefnirtera); ctihoenmsiciaml mperodpiaetretliyes.haInzaraddoduistiotno, ulinfed;er phthyesichaeladainndg ogfive"nIndasusttoriarlecHoyggniietinoen,Preavcatliucea,t"ionbrioeff estxapteomsuernests aanrde rheecaodminmgen"dSepdecifcicontPrroolcepdruorcees,d"urbesr.iefAdlseos,criupntidoenrs tahree gmivedenicaolf pfrirosctedauidr,esp. roFpinhaylllayc,tica mliesatsuorefs,reafnerdenscpeesciaisl gthiveehn.eaIdtinigs oaflso"RseicgonmifimcaenntdetdhaMt aixnimeuacmh Actamseo,spuhnedreicr oCfonthceenrtreactoiomnm,"enadasttiaotne.mTenhtisisapmparodaechas retopretsheentsbasbiys fparrobltehme omfoessttabdleissihrianbglehywgaieynicofstadnedaalrindgs. Mweitrhe litshtes iomf pnourmtabnetrsthleaatvealml uacvhailtaoblbee idnefsoirrmeda.tiIotnisreelxattrievme eltyo the establishment of the standard be included with it. BASES FOR HTYHGEIEENSITCABGLUIISDHEMS ENT OF inTthhee eUstnaibtelidshSmtaetnets oisf nbuasmedberpsrifmoarr"iltyoleornabtlweolimkinitdss" opferiiennfcoer.maTthioen:scaiennimtifaicl erexspeearricmhenwtshicahndprhoudumcaens tehxe sbiatiseics, dreasteaaricsh claarbroierdatoorinesb, yanpdrigvoavteerninmdeunsttaryl ,aguennicvieesr. Tmhaeny reUsunlittsedofStsautecsh teincvhensitciaglataionnds sacrieentpifuicblijsohuerdnalisn. niqInuesomofe acpaspelsy,inpgartiacnuallaorglyy nwewithchoetmheicralsw, etlhl-ekntoewchn cuhnetmil icvaallliyd sdiamtailahravmeatbeereianlsachcausmsuolmateetdim. es been used utiTlihzee aclolmamvaititleaebsleorpuobrlgiashneizdatiaonnds ruenfpeurrbeldishtoedabdoavtae ilnevealsrrivwihnigchatwitlhl eiprrojvuiddgemaentbsasaiss tfoor thseafekgiunadrsdinogf employee health. Animal Experiments phTyshieologtiecchrnesiqpuonesesofin eavnaimluaaltsingas atoxmiceoalnosgicof parned dagicetnintsg, oproossthibelre enefvfeircotsnmoefntatolxcicondmitaiotenrsialosn, mphaynsihcaasl floienldg. bIeifenspaiteroouftitnheis,tohoolwienvetrh,ethoecrceuphaatsionbaelenheliatlttlhe ainttveemstpigtatmivaedetetcohnpirqouveisdeina sitnadnudsatrrdiaizledtoxaipcporloogacyh. Itno mthaenyeffreecstpsecotfs athtiosxiisc fmorattuenriaatle,onfora inbiodloeagliicngsywsteitmh cliosnhseiddercarbitleeriafl.exUibsiuliatlylyisearrelqyuitreesdts inwiallppilnydinicgateestathbe cleotuhrasle doofsesfuarnthderthsetuedfyfe.ctsThoen dmifafgenreitnutdeorgoafnsacwuitlel iinmdpiocarttaencteheofsevvaerrioituys orofuttehse oafcuabtesorhpatzioanrd. Caonrdollathrye iannfdorpmoastsiiobnle rseylnaetirvgeistitcoefsfpeecctsiecsanvabreiaboiblittayi,nesdexa,t athgies, tfiomr ef.uAtulrleo, fmthoirse ienxftoernmsiavteiolnonwgi-ltlertmhenstupdroievsi.de a basis is Ingentheeralclayseaodfopnteewd sbuybstatonxciecso,lotghiestsfirsotr stienpduwsthriicahl luatbiloizraattoiorniesofinscrteheenindgetetersmtsinoantioenxpeorfimtoexnitcailtyaniismathlse. aTchuetsee efaferectsurseusaulllytingfofllroowmedsinbgyle dinejteacilteiodn,stiundgieesstioonf, oefrfecitnshoanlatsikoinn aenxdpeeryiemseanrtes. evIanluaateddd.ition, irritating forInan195e6xtaencsiovmeplseetreiescomofpimlataitoenriaolsf awcauste ptuobxliicsihtieeds u(5n).deTrhethpeurapuosspeiceosf tohfisthveoluAmeerowaMsetdoicbarlinLgabtoograettohreyr afovrailasbelveerdalataspoencie"sacuotef tocoxmicmityonolyf vaursioedus slaubbostraantocreys aisntirmataiolsn,asordeintehramlaitnieodn, boyf ofaratall odrospeas.r"enItnerathl eadinmtrino ddiutciotinosn intoflutehnicsinvgoltuhmee acthuete vtaorxioicuisty sifgonrifiacnaynt gcivoenn cthoemproautendofwaebresordpitsicouns,serdo.utTeheosfe adinmcliundisetratthioen,dossitee, oenf viinrojencmtieonnt,, atnedmpoetrhaetur rein,fluheanbcites,anindcltuodleinragncdei,seaestec,. cInhemadicdailtsiown,illitvawrayswpiothintsepdecioeustofthaantimthaels taonxdicistoymoef Wtimitehsinevtehne wsiatmhedsiftfrearienntthsetrationxsicoitfy thmeaysamdieffesrpewciietsh. age, weight, sex, and general condition of the animals. WILLIAMS 991 Btoecbaeuseceortfaianll tthheaste avllarieaxbpleesrimiteinstsviratruealclyonidmupcotesdsibilne fpirnedcisdeelytaitlheed sdaimsceuswsiaoyn. Ionf faalclt,suocnhly fraacrteolrys dionevsolvonede inFaonlloewxipnegrimaecnctu.mulation of data on acute effects, lionnhga-latitmioen, cfhereodniincg, eifnfejectcstioanr,e anthdenskisnt-uadbiseodrpttihornouegxh rpeesruimltsenotsf. eTahrleiernastcurreeenoinfgthteessets.isAdtetaercmoinnfeedrenbcye tohne Tinhe195T9ox(i6c)olVo.giKca.l RBoawsies aonfd ThhisreschoowlodrkLerismpitreVseanluteeds awnhicehxtehnasdivebeesnummmaadrey ovofer tahepekriinoddsofofmoobreserthvaatnion20s ysuemarsmabriyzedsevaenrdal tainbduulastteridalobgsreoruvpasti.onTshoisn dmisocrutassliitoyn, ofogoyd, minitcarkoep,atbhoodloygwy,eihgehmt,atoorlgoagny,wbeliogohdts,urgeraossniptraotgheonl, cclhionliicnaelsteurraisnee. analyses, central nervous system, and paTrtaibculelsarI-eIfVfecstsumwmeraeriozbinsgervtehde ufrnedqeurenvcayriowuisthciwrchuimch setraanlcebsiogliovgeicananidndibciaotciohnemoicfalthedestiegrnmifiincaatnicoenso.f Tsehve sTiganbilfeiscaIncaendofIIgraonwdththestusdigiensificaanndce cohfoltihneestleivraesreanind kinidnTeaybleins IaIlIl aonfdthIeVs.eTshtuediaeusthaorres w(6e)llpodienmt oonusttrathteadt kthinedres iosfinmcreeaassuinregmpernetsssuirne tfhoer mbioorceheamndicamloarendpretocixsie cologic fields as a means of establishing valid threshold leixmcietlsl.enTtheoybjepcotiivnet oauntd, hoonweevtoewr,atrhdatwwhihcihle atlhlisshisoualnd sutsreiveo,f itavisaileasbsleentimalantphoawt eorneanmdakfeuntdhse mtoosotbptarianctitchael mseot stfomrtehaniinngftuhlisinpfoaprmeratiaorne. Tthhoesecrwitheirciah wahreichmaorset wthiedelfyieldu.seTdhaendbecsterthaoinpley faocrceipntcerdeasbiyngallouwrofrkuenrds oinf kconmowelefdrgoem dthereivdedeveflroopmmenatniomfalnewexpteercihmneinqtuses maunsdt snteawte:criteria. In summary, the authors of this paper neIwn csrpitietreiaobfeitnhge dfeavcetlotpheadt atnhderetesaterde tmodaanyy, vthaeluedatoafprceesretnaitned ohferetihne emolpdhearsizcerittehreiah. igIht wthoouseldstsuedeimes ownhliychpreuxdpeernitenctoe hmaaskeshouwsen otof boenlymothstosperocdruitcetriivae.shTohwisindgoeas hniogth mdeeagnreethaotf epfofirctieedncyherieninthsehosuelrdiesbeofusiendv,esbtuigtatcioenrtsainrley ittoxsiucoggloegstiscalthasttudthyeydesshigonueldd btoe bdaestiecrmtoineanya threshold limit for repeated exposure. anOd nemoorteheratsteetntoiofncriatereria thwohsiech pihsysaitotlroagcitcingstumdoieres wInhicthhecasnymbepomsiaudme omneanntiiomnaelds aasbwoveell, asDro.n JhouhmnanAs.. Zphaypspi,oloJgr.ic (7o)bsedrisvcautisosneds stuhceh iams psoyrsttaonlicce anodf udtiialsitzoinligc FREQUENCY WITH Crieteffreicat of GHreomwatthology CCNlinSical urines Cholinesterase Table I WLHEIVCEHL AATPWARHTICICHULAANRY EEFFFFEECCTT WWAASS OOBBSSEERRVVEEDD A(6T) THE LOWEST DOSAGE Data from 1952-1959 Da2t2a-2f5roymearlsast Oral a % 64 (172) 1 (79) 371.3 41 ((170)9) 143.7 8 (10) 80 Vapor a % 161 ((3281)) 425 01 ((372) ) 03.1 All routes a % 1525 ((411700)) 37 2.9 52 ((14431) ) 43..56 8 (10) 80 Number of positive findings (number of observations) Table II FREQUENCY WITHDOWSAHGIECHLEAVELPAARTTIWCUHLICAHR AENFFYECETFFWECATSWTAHSE OSBOSLEERVEEFFDEC(6T) AT THE LOWEST Crietfefreicat of GHreomwatthology CCNlinSical urine Cholinesterase Data from 1952-1959 Oral a % Vapor a % 250 ((17792)) 105 21 ((3281)) 55 40 ((170) 9) 03.7 01 ((732) ) 03.1 4 (10) 40 D a2t2a-2f5roymearlsast All routes a % 441 ((411700)) 110.6 05 ((4134)1) 03.5 4 (10) 40 "Number of positive findings (number of observations) WILLIAMS 993 terms of the significance of such information in application to humans. Human Experience abWouhtilteheanpiomssailbldeatlaevpelrsovoifdetoxsoicmemabtaesriisalfsorwjhuidcghmmeanyt btoe uhsuemdasnasfelwy iitnh incdoumsptrlye,tethceoyncfiadnennocet.beThexetraupltoilmataetde cvrailtiedriitay omfusstuchcomcreiterfiraomis bhausmedanonextpheerieanmceo.untThoef epxepoeprlieencaend intimteermosf oefxpobsouthre, nounmbtehres mofetheoxdpsoseodf peveoalpulaet,ioanndoofnththee ecfofemctpsletoefnesthseoftotxhiec emvaaltueartiiaoln oonf eoxfpothsuesree lleevveellss inwitthhe heunmvairnonmexepnotsuarne.d Dcoartraelawtiiothn creofnetrreonlcleed toexhpuermimanentesffeactnsd ariendoubsttariianledenfvroirmonmboetnht exIpnosuthrees. case of irritants, for example, such factors aesxpoosduorre wdehtiecchtioanre, isrernitsaotriyng rteospeoynesse,,skainn,d anledveulsppeorf hreusmpiarnatsoruyndterarcct ohnatrvoellebdeecnonsdtuitdioiends. qIunangteintaetriavle,lysucihn sptluadnitesu, sceo, mpbroinveiddewainth aedxepqeuraietencbeasgiasinfeodr wesittahbliaschtuinagl oItr icsonmfuircmhinmgohreygdieifnfiicculsttatnodaprrdosvidfoer asuscohunsdubbsatasnisceosf. htiuvemlyanloenxgpepreireinocdes ofofr tismubestbaenfcoerse wprhoicdhucrineqgueirveidreenlcae oreflaitnivjuerlyy. rWaphidelryeaasntdhebyacsuimtepleeffepcrtoscecdanurebse, leovnaglu-taitmede dweotrakileerds asretudreieqsuiroefd ctoontprroolvleidde gardoeuqpusateofeviinddeuncsteriianl tchheronciacseinjoufry.those substances which may produce indTuhsetrikailndesxpoefriiennfcoermwaittihonvawrihoiucsh cahreemaivcaaillsabflaell frinotmo pthlareinetsbaassicsoccaiatteegdorgieesn.eOranlley owf itthhesteheissleinmsoitreyd rtedspcoonmse aofrfewctiitnhgmsokrien,seevyeerse, foorrmuspopferacruetsepiirrarittoartyiontrarceta.ctTiohnes soefcoexnpdoskeidndwoorfkmdaetna. Trehsueltthfirrodmisctlhineicraelsueltxaomf ihnuamtioann teosxtaicbolilsohgiincgohrygpiheynsiicolostgaincdastruddsiessu.chTomebdeicoafl vinaflouremian ttoionthme ucstonbceenctroartrieolnastedtowwithhicahdewquoarkteersdathaavreelabteineng exIpnosehdis. paper "Improved Communication. Hygienic S23ta8ndvaarldusesfofrromDailtyheIn1h9a5l6atiAonm"erSicmanythCo(3n)ferreevniceeweodf GhiosveinrntemrpenrelitdatiIonnduosftritahlesHeyvgaieluneisst.s Hliset, htaosgeatlhseor ewviathl huuatmedant.heAnnaatunarelysoifs tohfe tshueppfoorutringkinddasta--ofansoimuraclesanodf ehsutmabalinshdinagta hiyngdiiecnaitcessttahnedarordles oinf stuhceh UexnpiteerdienScteateisn. dOaftaa wtoetrael uotfili2z3e8d vinalu1e0s8*w,hdicishtriwbeurteedanaaslyfzoelldowhsu:man CCloirnrieclaalteEdxWamiitnhatTiohneiorfEWxpoorksumreen Was 34 ILnedssusQtruiaalntCitoamtivpelaiTnhtsanorCOlibnsicearvl aOtiobnsesrvations 33 HHuummaann TSeonxsiocroylogDiactaor Physiologic Data 4120 t*hOerfethwee1r1e91v1aludeuspldicisattreisbuwtehderieninthetheabosavme etabmualtaetrioianl awpepreeaarecdtuaullnyd1e0r8 tsweoparoartemsuobrestahnecaesdinagnsa;lyztehdu.s there maItnerisaulsch wahnichexteanresivesolisltittales tuhsisedthtehraet artehermeaniys snteagnldigairbdlse pienodpulset.riFalorexsupcehriemncaeteraivalasilarebllieantcoe aisssipstlacoeudr panriamloagryilyas ognuidaensiminalsetetxinpgerilmimeintsts. and the use of yeFarosr otfheexmpeorrieencceominmounsinignduthsetrmialhacshepmroicvaildsedmatnhye Sneuccehssaerxypebriaecnkcgeroiusndgenteoralvlyerifoyf aexinsteignagtivsetanndaaturdres.. Wcohrreerleateitdiswsiuthpploervteelds boyf celxinpiocsaulreo,r apshyisnioltohgeiccaalsedaotaf tchoelletaegnu-eysea(r10s)t,udthyeofinbfourtmylatailocnohiosl mbyosSt tseirgnneirficaanndt. his geSnuercahl mpheydsiiccaall pcroongdriatmiosn aorfe edmepsilgonyeeeds taonedvatoluiantceluthdee sppreocviifdice peahrylsyioelovgidicencteestsof winhjiuchry.mSatyudibees oexf ptehcitsedtyptoe ahryegiebnyicfasrtantdhaerdms.ost valuable for establishing valid SUMMARY AND CONCLUSIONS forIninshuamlamtiaorny, iint ctahne boeccsutaptaetdionthaalt hheyaglitehnifciesldtanindarthdes bUensittekdnoSwtantebsioacrheembiacsaeld, toonxicothloegica,ppplhicyastiioolnogioc,f atnhde pexaptheorileongcice. tIencvhensitqiguaetsiontso araenimcaarlrsiedanodn tboy hpurimvaatne ienrdnumsetrnyt,alunaigveenrcsiietise.s,Trheeseaarncahlysliasbooraftosruicehs, daantda gaonvd ibnytesrtparnedtaartidosngirnoutpesrmcsomopfohseydgieonficcosmtapnedtaerndtsscisiendtoisntes rfeiepldre.sTenhteingvaleivdeitryy offactehteseofsttahnedaordccsuipsatdioenmaolnshteraatlethd bUynittehde Slotawteso.ccVuepriaftiieodnaclasdeisseoafsesuactthaciknjuraryte airne tthhee resMulatnyof aepxpproosaucrheess faarreabboeviengthme aedsetabtolishtheed plirmoibtlse.m ohfeaelsthtabfliieslhdi.ngIthybgecieanmice sotabnvdioaursdssoinmethetimoeccuapgoatiothnaatl rinesesaormche cpaseeospluetiliinzinvgarvioaurysinpgartteschonfiquthees. wAosraldrewsuelrte, voardlueers offormasogmnietudsueb. stIanncaens adtitfefmerpbt ytoasgemt uscohmeasunani pfircoavtiiodne ina thmeecbhaasnicismapptrooacphertmoitthea pmroubclehm barnodadetor hexecahltahngewoorfkeinrsf,ormthaetioPneramndandenatta Ianmteornngatoiocncuapl atCioonmal tmoisssitoundyonthIinsdupsrtoriballemM.edTichiinse sSeutbucpomamSiuttbeceomhmelidtteae soyfmTpooxsiicumSubosntanMceasxiinmuImndusAtrllyowinabPleragCuoe,ncCeznetrcahtoioslnos Svaykmiap,osoiunmA, pwrilhic1h4-17a,pp1e9a5r9e.dThine Tforaunrsascetciotinosns,ofdtehael wThitihs gsteanteermalenatreoafs porfinacgipreleesmiesntanamimonpgorttahnet dfeirlsetgastteesp. ipnoretasntatblfiisehldin.gOinntethrneatbiaosnisal ocfotohpiserawtioornk iint itshihsopimed onfot aonlsyertiheast wofe ciannterlonoaktiofnoarwllyardatcocetphteabdleevehloypgmieennict swtaitnhdarerdgarvdalutoesgebnuetratlhaptrinacgirpeleems eanntdctaon mbeethoobdtsainanedd opfroscuecdhuresstanwdhaircdhs.wTillh ebepuretisleiznet dSiynmtphoesiuemsta, bwlishhicmhenits wthiell,seIcohnodpe,uncdryesrtatlhliezeaeuvspenicefsurothf etrhetheSutbhcionmkimngitteoef ethsotasbeliisnhinthge soocucnudpastitoannadlarhdesalttoh bfieeldusceodncienrnaesdsuwriinthg safe industrial environments. Index of Authors Adams, C. A., 93-98 Agranoff, Barbara, 351-353 Ahlmark, A., 201-203, 653-656 Albahary, C., 203-214 Anderson, William H., 656-661 Ashe, William F., 835-839 Ashman, George R., 351-353 Askey, E. Vincent, 62 Axelsson, Bengt, 201-203, 977-980 Balkanyi, N., 465-466 Bambino, C. F., 281-283 Barhad, Bernard, 661-663 Baselga-Monte, M., 663-668 Bauer, Louis H., 85-86 Baughn, William L., 668-672 Bayonet, Natalio, 214-217 Belding, H. S., 839-845 Belknap, Elston L., 217-226 Benitez, Julio Cesar, 531-532 Benoit, Joyce N., 266-270 Benton, Joseph G., 314-316 Berdan, C., 845-847 Bernath, Zoltn, 227-230 Bielecka, W., 795-798 Biggs, M. W., 147-150 Bissonnette, Grace, 230-232 Blatz, Hanson, 463-465 Block, Duane L., 678-679 Bloomfield, John J., 98-101 Bojin, S., 677-678 Bolis, L., 817-818 Bonjer, Frederik H., 672-675, 848-850 Bonnell, J. A., 93-98 Bordes, H. J., 850-857 Boudene, C., 209-214 Box, Arthur, 298-301 Brand, Morris, 603-605 Brandaleone, H., 937-939 Breitenecker, Leopold, 675-676 Brennan, Miriam C., 314-316 Brieger, Heirmeh, 720-725 Brinkman, Geoffrey L., 678-679 Bronstein, Lewis H., 232-237 Brouha, Lucien, 857-862 Brown, J. R., 862-864 Brownlow, James A., 605-607 Bruce, T., 653-656 Brykalski, D., 800-801 Burger, G. C. E., 864-869 Burney, L. E., 63-64, 101-104 Cadariu, Gh., 237-238, 676-678 Cancella, Lopo de Carvalho, 56 Cataldi, R., 181-182 Cavagna, G., 770-772 Cavigneaux, A., 203-209 Charsha, R. C., 580-585 Churchill, A. G., 281-283 Ciuhandu, Gh., 237-238, 676-677 Coates, E. Osborne, Jr., 678-679 Cobo de Bias, Eliseo, 238-240 Collins, S. K., 281-283 Colonna, Francis L, 241-242 Conrad, Reuben, 869-870 Cotabish, Harry N., 544-551 Cracuin, O., 679-681 Crisan, V., 237-238, 676-677 Cruickshank, W. H., 105-106 Dankner, A., 237-238, 676-678 Daw, H. T., 86-87, 106-110 Deichmann, William B., 871-872 Derville, P., 242-243 Desoille, H., 209-214 Didonna, Pietro, 110-114 Dinatale, Peter J., 244-245 Dinischiotu, G. T., 343-345, 679-681 Dohan, F. C., 182-184 D'Onofrio, Virgilio, 181-182, 958-959 Dossett, Burgin E., Jr., 656-661 Dror, K., 245-246 Duffner, Gerald J., 939-942 DDunsltaepr, ,MH. . J.,218114-2-19138 Durham, Thelma J., 246-249 Dutkiewicz, Tadeusz, 681-686, 795-798 [997] 998 Eckardt, Robert E., 7-10, 64-65 Eckhardt, W., 850-857 Elkins, Hervey B., 981-983 Erhardt, J. Th. G., 850-857 Estadella-Botha, S., 663-668 ' Fabre, Ren, 686-692 Felton, J. S., 413-426 Ference, Anne M., 12-14 Ferran, G. H., 486-503 Fiandaca, S., 353-359 Finulli, M., 770-772 Fischer, R., 872-876 Fisher, R. . W., 250-256 Folsom, Marion B., 72-82 Formnek, J., 714-721, 872-876 Fornells-Martinez, E., 663-668 Forssman, Sven, 68-72, 257-258 Fortuin, G. J., 258-259 Fournier, Et., 694-698 Frad, G., 259-260 Frantik, E., 714-721 Frantikov, D., 872-876 Friberg, Lars, 201-203, 977-980 Friedland, I. G., 692-694 Gabor, Sylvia, 465-466 Gasque, Mac Roy, 260-263 Gaultier, M., 694-698 Georgescu, A. M., 343-345 Ghosh, P. K,, 426-427 Gillquist, B., 257-258 Glorig, Aram, 699-700 Goldman, Rose, 314-316 Goldstein, Bernard, 263-266 Goldstein, David H., 266-270 Gorospe, Alfredo A., 636-639 Gradina, C., 700-702 Grant, Ellsworth S., 118-120 Greene, Katrine R. C., 314-316 Grimaldi, John V., 607-608 Grimlund, K., 703-707 Gross, Paul, 707-712 Gucciardi, G., 259-260 Guymer, R. F., 270-275 Guyotjeannin, Ch., 694-698 Gwozdz, B., 795-798 Hamilton, Gilbert L., 656-661 Hargreaves, Margaret S., 275-278 Harris, E. S., 281-283 Harris, William B., 466-472 HHaatycehs,, TW. aFy.,la8n3d9-J8.4,5Jr., 120-122 Hertig, B. A., 839-845 Hinchcliffe, R., 712-714 Hine, C. H., 281-283 INDEX OF AUTHORS Hinkle, Lawrence E., Jr., 283-288 Hipps, John G., 608-610 Hogan, Edward J., 610-613 Holden, F. R,, 281-283 Holm, A., 257-258 Holmquist, Carl-Eric, 122-126 Holstein, Ernst, 278-281 Holtz, John, 783-785 Horiuchi, Kazuya, 288-289 Horvath, M., 714-721, 872-876 Hueper, W. C,, 473-486 Hughes, James P., 879-882 Hyatt, E. C., 486-503 Inoue, Toshi, 289-290 International Labour Office, 721-724 International Symposium on Maximum Allowable Concentrations of Toxic Substances in Industry, 33-39 lorga, M., 341-343 Jensen, C. R., 486-503 Juin, Grard, 942-947 Jullien, Georges, 724-726 Kammer, A. G., 427-428 Kantor, M., 753-755 Kazantzis, G., 290-298 Keatinge, Gerald F., 298-301 Keenan, Robert G., 503-506, 783-785 Kehoe, Robert A., 126-129, 433-436 Kesy, Irena, 726-730 Killens, Richard, 783-785 King, E., 301-311 Kingston, James R., 911-917 Kitagawa, Tetsuzo, 506-512 Kiviluoto, Raimo, 311-312 Klein, Irvin, 613-615 Klutas, Edna May, 428-431 Kopp, John, 783-785 Kruger, Daniel H., 615-621 Krger, P. D., 971-973 Kubota, Juko, 313-314 LaBelle, Charles W,, 730-735 Lachnit, V., 947-950 Laham, Souheil, 686-692, 735-738 Lammers, B., 876-878 Landry, A. S., 512-519 Lavergne, Rafael, 214-217 Lehmann, Gunther, 878-879 Leoca-Radu, Mina, 349-351 Letavet, A. A., 431-433, 891-892, 83-87 Liber, Amour Fiscus, 738-740 Lieben, Jan, 316-319 Lienhard, Wendell F., 879-882 Lillis, R., 679-681 INDEX OF AUTHORS 999 Linch, A. L., 580-585 Lind, A. R., 882-887 Liniecki, J., 800-801 Littler, T. S., 712-714 Lubin, Isador, 621-622 Lund, O.-E., 740-741 Lundervold, Arne, 887-891 Lutier, J., 401-402 Lutz, Earl F., 184-186 McCallum, R. I., 741-745 McClintock, R. S., 879-882 McKerrow, C. B., 745-749 McNerney, James M., 707-712 Magnuson, Harold J., 129-131 Malysheva, A. E., 891-892 Manheimer, Robert H., 314-316 Matthews, James, 131-134 Matuoka, Syukiti, 893-902 Maxfield, Mary E,, 857-862 Meiklejohn, A., 134-138 Meila, I., 677-678 Metzner, Franz N., 316-319 MMiichhaoilna,, RL.,, 990042--990084 Mikaelian, Michel, 320-322 Mikisha, A., 714-721 Milijic, Bosko, 950-951 Miller, S. E., 937-939 Milox, M., 908-911 Minard, David, 911-917 Miskolczy, Wilhelm, 322-324 Mitchell, R. N., 486-503 Moise, Gh., 676-678 Molfino, F., 952 Monaco, Alfred, 749-753 Morris, George E., 324 Morrow, C. S., 753-755 Moscovici, B., 341-343 Moss, N. Henry, 182-184 Motley, Arthur W., 623-624 MMooyuenrt,aBinu, rJtoohnnJT., .5, 1798-35-27285 Muica, N,, 679-681 Murray, Robert, 139-145 Nadudvary, George, 465-466, 755-757 Nale, Thomas W., 625-628 NNaesmtobrae,sTcua,tsBu.j,i,67795-76-87158 Newnham, C. T,, 324-325 Niebroj, I., 795-798 Nixon, James, 699-700 Noro, Leo, 326-335 Norviit, Lembit, 952-957 Norwood, W. Daggett, 335-338 N y s t r o m , A ., 257-258, 653-656 ' Olloqui, Fernando Flores, 628-631 Oyanguren, Hernn, 227-230 Pafnote, Maria, 845-847 Paggi, Edoardo, 758-767 Pancheri, Giovanni, 145-146, 767-768 Parker, H. G., 147-150 Patrascu, M., 465-466 Payne, William W., 473-486 Pendergrass, Eugene P., 768-769 Pendergrass, Henry P., 768-769 Perales y Herrero, Narciso, 631-632 Pernis, B., 770-772, 817-818 Pesce, Giuseppe, 958-959 Petrescu, Leonid, 661-663 Pettinati, L., 348-349 Petrovic, Lj., 338-341, 368-371 Phillips, A. M., 553-556 Pietschmann, H., 947-950 Pilt, L,, 341-343, 679-681 Piotrowski, J., 780-782 Piscator, M., 201-203 Plumb, Carl S., 260-263 Plummer, Norman, 283-288 Poleti, D., 338-341, 368-371 Potter, A. Lloyd, 150-155 Powles, William E., 351-353 Pradel, J., 522-531 Preda, N., 343-345 Princi, Frank, 433-436 Puertas, Benito Nogales, 633-634 Quer-Brossa, S., 663-668 Quigley, J. A., 65 Radcliffe, J. C., 65-66 Rdulescu, L C., 343-345, 679-681 Rae, Stewart, 772-776 Rainsford, S. G,, 345-348 Rasetti, L., 348-349, 359-361 Raucher, Karl, 349-351 Reeve, A. Louise, 634-635 Renker, K., 917-921 Riedesel, M. L., 839-845 Riegrt, A. L., 819-825 Rigner, K. G., 257-258 Risquez-Iribarren, Rafael, 155-158 Rogan, John, 772-776 Ross, W. Donald, 351-353 RRoossssii,erM, Par.ioH,.,97670-69-67180 Rotta, C., 353-359 Rubino, G. F., 359-361 Rye, W. A., 361-364 Sakai, Yoshimichi, 158-162 Salmowa, J.,''780-782 Sands, Frederick W., 531-532 Santillan, Jose S., 636-639 Sarfeh, R,, 436-438 Saruta, Namio, 532-535 Savicevic, M., 338-341 Sawyer, William A., 438-441 Scansetti, G., 348-349 Scheel, Lester D., 783-785 > Schepers, G. W. H., 786-795 Schermerhorn, W., 850-858 Schiller, Hans, 961-962 Schindl, Karl, 364-365 Schmidt, Heinz-Giinther, 365-367 Schmidt, Marjorie D., 367-368 Schmidtke, H., 921-923 Schulte, H. F., 486-503 Schunck, Karl-Hans, 377-378 Schwartz, Louis, 639-642 Seles, L,, 237-238 Serati, A., 963-965 Sherrill, S. S., 281-283 Shipman, Thomas L., 642-645 Shoib, M. 0., 85, 162-166 Sick Absence Statistics Committee of nent Committee and International on Occupational Health, 40-55 Silverman, Leslie, 441-448 Simpson, H. Marjorie, 448-452 Simu, George, 755-757 Smith, Paul E., Jr., 857-862 Sodergren, David, 122-126 Sox, Ellis D., 281-283 Spett, K., 795-798 Spiers, F. W., 535-540 Spioch, F. M., 795-798 Stankovic, M., 338-341, 368-371 Staskiel, L. J., 753-755 Steele, Earl C., 371-373 Steele, Margaret L., 66-68 Steiner, S. D., 373-377 Stokinger, Herbert E., 540-544 Stopps, Gordon J., 857-862 Stowell, Thomas E. A., 186-191 Strange, John P., 544-551 Sumner, Philip, 314-316 Symanski, H.-J., 798-800 Szpakowa, T., 800-801 Szymczykiewicz, K., 801-805 the Perma Association Vacher, J., 401-402 Valentin, H., 810-817 Van der Velden, W., 850-857 Van Liew, Hugh D., 911-917 Van Valzah, H. J., 678-679 Vigan, C., 965-971 Vigliani, Enrico C., 87, 452-457, Viles, Frederick J., Jr., 556-563 Villarroel, Sergio, 227-230 Viola, P. Luigi, 818 Voelz, George L., 564-569 Vosburgh, B. L., 931-933 770-772, 817-818 Wade, Leo, 7, 61, 88 Wald, Neil, 569-572 WWaallkshe,r,RMicihldarrdedFL.,, 614657--614689 Warnock, Dorothy M., 402-404 Wassermann, M., 572-580 Weaver, Neill K., 381-387 Wechselberger, F., 191-194 Wells, R. Lomax, 170 Westrick, Marian L., 707-712 Wetherhold, J. M., 580-585 Wheatley, B. M., 585-587 Whipple, G. Hoyt, 171-178 Whitney, L. Holland, 283-288 Wiecek, E., 801-805 WWiiellliaanmds,,HC.,ha7r4l0e-s74R1., 988-994 Williams, Katherine, 587-590 Williams, May M., 194-197 Williams, N,, 819-825 Willman, Helvi, 404-405 Winter, Kurt, 405-410 Worth, G., 826-827 Wyndham, C., 924-931 Tabershaw, Irving R., 11-12 Taylor, Edmund W., Jr., 182-184 Teisinger, J., 987-988 Teso, G. A., 359-361 Thaxter, M. D., 147-150 Thom, W. F. J. M,, 379-381 Thoma, George E., 569-572 Thompson, A. R., 301-311 Thorpe, John J., 381-387 Tompkins, Paul C., 551-553 TTrroipissia,, FRoordtuicnaa, t8o0M6-8a1r0ia, 387-397 Truhaut, Ren, 33-34, 39, 209-214, Tucker, F. E,, 553-556 686-692 Yingling, Doris B., 457-459 Yoder, John D., 590-592 Yoshimi, S., 827-828 Yount, Hubert W., 649-650 Zahorski, Witold, 828-832 Zanetti, Ennio, 767-768 Zannini, D., 971 Zielinski, John F., 592-600 Zorn, 0., 971-973