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1954 ANNUAL
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dustrial Hygiene Digest
INDUSTRIAL HEALTH NEWS
LITERATURE ABSTRACTS
MEDICAL ENGINEERING CHEMICAL TOXICOLOGICAL LEGAL.. cUcinon* and trnd
*
TD^^a'tfiL
-iqii-SS
INDUSTRIAL HYGIENE FOUNDATION
MELLON INSTITUTE
4400 FIFTH AVENUE
PITTSBURGH 13. PA.
Industrial Hygiene Digest
January, 1954
months than after one month. With the middle grades then were two types of reaction, possibly due to agglomerations and discrete particles respec tively. The decrease in proliferation from the finest may be due either to elimination after solution or removal by microphages. Experiments are being continued.
71 Occupational Lung Damage in Ships1 Repairers. JL. Dun^er, M. Sanger, & D. T. J. Bagnall. Brit. J. Radiol. 26, 590-594 (Nov. 1953).
Occupational lung damage in ships' repairers ("boiler-makers"), due to inhaled dust and/or fumes has been described for the first time. Analysis of the materials and the dusts to which these men are exposed while at work revealed the presence of free silica and iron compounds. Two broad groups are described, namely those with definite radiological changes and those without. Each group may be subdivided into those with severe symptoms, especially dyspnea resulting In incapacity, and those without symptoms. Post-mortem findings of severe emphysema with slight pneumoconiosis are reported in two men belonging to the group, with extreme incapacity in the absence of radiological lesions.
- - Authors' summary
72 Asthma and Silicosis. Queries and Minor Notes, J, Am. Med, Assn. TsT: 1327 (Dec. 5, 1953).
Asthma occurring for the first time in a 52-year-old person can be aggravated by silicosis. The type of dyspnea caused primarily by silicosis is due to damage of the lung parenchyma and to emphysema. In some persons with silicosis, bronchospasm is induced secondarily. It should also be remembered that a 52-year-old man may have allergic infections or cardiac asthma for the first time. If the patient in question has true asthmatic episodes (relieved by epinephrine or aminophylline), a search for other causative factors should be made by a series of observa tions such as examination of the sputum for eosinophils and neutrophils, skin tests, and examination for hypertensive, coronary, or syphilitic heart disease.
73 Asbestosis Bodies and Pseudo-Asbestosis Bodies. J. Ruttner. Schweiz. Z, Allgem. Pathol, u. Bakteriol. 15, 628-631 (1952). German.
The literature on asbestosis bodies is reviewed. Similar products
were found by the author in a lung which only contained carborundum and
graphite; the bodies were formed around plates and needles of carborundum.
The protein and iron which form the bulk of the "bodies" must come from
the lung tissues and not from the mineral matter of the dust. Similar
bodies could also be produced in vitro but they have not so far been found
in animal experiments.
-- Bull. Hyg.
March, 1954
: :he eruption, especially whether it coincides with the work period; ...d 14) character of the eruption, with consideration of possible occupa-
jaal aggravation of a non-occupational dermatitis. The limitations of significance of patch tests are discussed. The problem of fungous
sections in relation to occupational dermatitis is considered. Some cases : dermatitis require study, even by an experienced dermatologist, before
etiological diagnosis can be made.
rcnaational Skin Disease. Public Health Service Publ. No. 306, . d. Dept, of Health, Education, and WeLfare, and Controlling Chemical .awards, Series No. 10. U. S. Dept. Labor, Bureau of Labor Standards. .5 pp. (1953). For sale by Supt. of Documents, U. S, Govt. Printing office, Washington 25, D, C. 10 cents.
This brief pamphlet presents the essentials about occupational skin .. iease--direct and indirect causes, and prevention and treatment on the
ire of the employer and the worker.
.^otfscos Warts and Other Dermatoses in Workers with Lagging Materials. Farris. Rass. med. ind. 22, 1-17 (Jan. - FetT. 1953), Italian,
The author has investigated cases of warts on the hands of 29 workers
.m lagging materials, including asbestos cord which is wound around pipes,
^nous asbestos-containing slabs, and mixtures of asbestos and cement
a be molded to the shape of the tank or other object to be insulated. One to
.ur warts were found in every case. They are due to asbestos fibers which
j.'cnetrate into the epidermis and become lodged in the corium or true skin.
The epidermis shows acanthosis (thickening of the prickle-cell layer) and
hyperkeratosis (increased horny tissue) and the corium shows a granulo
matous type of reaction with the appearance of giant cells in some cases.
Exudative dermatitis may also be present. This condition is attributed to
the combined action of the hygroscopic and alkaline cement and the irritating
asbestos fibers. The gross and microscopic appearances of the lesions are
illustrated.
-- Cond. from Bull. Hyg.
Dermatitis Due to Pancreas. S. Tara, G. Bouwens, A, Cavigneaux, and V, Deiplace, Arch, maladies profess. M_, 44-46 (1953). French,
Two cases are reported of workers employed ir a pharmacological laboratory who experienced skin trouble when they manipulated pancreas preparations. Erosion of the skin with bleeding is a feature of this form of dermatitis. Similarly to papaya latex and pineapple juice, enzymes from
` pancreas exert a solvent action on the skin. -- Cond. from Bull. Hyg.
tnaustrial Hygiene Digest
August. 1 954
upon the PH. From albumin solutions having a concentration comparable with olasma only about one-tenth of the available adsorption sites on a quartz surface are filled at PH 7.4, The adsorption of proteins upon the quartz surface is not considered to be an important aspect of the silicosis problem.
--Authors' conclusions
905 The Presence of Asbestos Fibers in Urine of Workers Exposed to Asbestos h'azard, V. Wyss. Rass. med. ind. IZ, 55-56 (1953). Italian.
In urinary sediment of two asbestos workers asbestos fibers were seen;
the same finding was detected in urine of two female patients suffering from as-
bestosis, who had left their work seven years before.
-- Biol. Absts.
PHYSICAL ASPECTS OF THE ENVIRONMENT ______________________________________________ _______________
'95 dome Practical Aspects of Industrial Noise Measurement. L. J, Proulx. Arch. Ind. Hyg. L Oec, Med. 9, 496-502 (June 1954).
Some of the instrumentation problems faced by an engineer who must evaluate industrial noise environments are discussed. An array of equipment which includes a sound level meter, octave band analyzer, tape recorder, dynamic microphone, audio oscillator, vacuum tube voltmeter, high-fidelity crystal head phones, cathode ray oscilloscope, and a good quality loudspeaker is described. The use of the tape recorder and oscilloscope for measuring impact noises is given particular attention. Various calibration checks are described.
The Locus of Short Duration Auditory Fatigue or 11 Adaptation.11 J. D. Harris and Anita L. Rawnsley. J. Exptl. Psychol. 46., 457-461 (1953).
Auditory adaptation, defined as a reversible shift in threshold following very mild acoustic stimulation, was distinguished from true auditory fatigue by four criteria: (1) the non-cumulative effect of stimulus duration; (2) the temporal course of return to normal threshold following stimulation; (3) the relative fre quency region of maximum threshold shift following pure tone stimulation; and (4) the shape of the curve of Loudness (recruitment.) This experiment sought to throw light upon where, in the auditory system, adaptation occurs. By the tech nique of simultaneous binaural loudness balancing between one normal ear under going a threshold shift of a preceding adapting stimulus, it was possible to demon-
an accelerated growth of recruitment in the adapted ear. The intimate
29.
St Hvgiene Digest
September, 1934
foremost in disabling silicosis, emphysema stands out as the cause. Emphysema atone w.th its shortness of breath may lead to a condition simulating asthma and ;-.ii no specific association with silicosis. In a silicotic patient with emphysema, a coexisting bronchitis may exaggerate the emphysema and thus further the total c.scur^ances. On" an organic basis, exposure to silica will not be more harmful to an asthmatic person than to any other worker. On a psychogenic basis, the asth matic person is prone to react unfavorably to any dust and therefore on an emotion al oasis may not get along well in the presence of silica dust. The correspondent .s referred to the report of the Third Symposium on Silicosis at Saranac Lake, '0j7 for a fuller discussion.
D.itrjbution of Mineral Particles and Fibers in the Lung after Exposure to Asbestos 2 J. F. Knox and J. Beattie, Arch, Ind. Hyg. & Occ. Med. 30-36 (J'.iiy 1954).
The particle-size distributions in the incombustible and acid-insoluble residues from the lungs of 27 persons who had been exposed to asbestos dust were determined. The number of particles with greatest lengths in excess of 26 microns ''as considerable up to the eighth year after the last exposure to asbestos dust and '...m. sharply fell. The number of particles within the size ranges of five microns `cb less and between five and 15 microns remained constant over a very long period 'rose cases which showed no sign of asbestosis or minimal fibrotic change. The -ases of severe asbestosis showed a significant rise in the numbers of such particles.
It is considered that the mechanism which is concerned with the production o: .'jir.an asbestosis is not the same as that which is responsible for the production of asoestotic changes in experimental animals exposed to high concentrations of asbes-os dust. The appearance of such changes seems to be related to the breakdown of asoesiosis bodies which may liberate some fibrogenic agent.
-- Authors' summary
Mineral Content of the Lungs after Exposure to Asbestos Dust. I. F. Knox and J, Beattie, Arch. Ind. Hyg. E*Occ. Med. 10, 23-29 (July 1954).
The mineral content of the lung parenchyma, the lung hilar region, and
'me tissues of the pleural and subpleural regions of the lung has been determined in
lungs from 27 workers in the asbestos - textile industry. The exposure time varied
from five to 33 years, and the time interval between the last exposure to dust and
death (survival time) was from less than one year to 21 years. There was an indica
tion that the mineral material found in the lungs increased in amount as the exposure
time lengthened. The amount so accumulated varied considerably from person to
person. As the survival time increased, the mineral content of the lung tended to
decline but again at a very variable rate. The severity of the asbestotic lesions
"1 the lungs found at death was related not to the mineral content but to the sum of
* exposure and survival times,
-- Authors' summary
1 iuatrial Hygiene Digest
December, 1954
ions on the surface irregularities produced by removal of alumina and other im
purities. The presence of these ions enables the silica surface to attract a greater
number of hydroxyl ions from the solvent medium, with the subsequent formation
of highly soluble silicic acid,
-- Cond, from authors' conclusions
;97 Physicochemical Studies on Dusts. 8, Some Sorption Properties of Siliceous Dusts, J. G. Gibb and P. D. Ritchie. J. Appl. Chem. 4^ 483-467 (Sept, 1954).
Rock crystal, Lochaline sand, and vitreous silica (Vitreosil) dusts alL
show reduced affinity for a dyestuff cation on removal of the disturbed outer layer
from the particle surfaces. This layer of amorphous silica is therefore more re
active than the .underlying core in sorption processes, just as in solution processes.
In the case of vitreous silica, there is probably a physical difference between the
outer amorphous layer and the nominally amorphous core, such as a more open
structure. Heat treatment and repeated acid extraction have the same effect in
both sorption and solution experiments. Alteration of the surface is probably
responsible in both cases.
-- Cond. from authors' conclusions
,1?8 The Effect of Quartz Dust and Aluminum Phosphate on Certain Enzymes. B, Helferich and Erika Schmitz. Beitr, Silikose-Forsch. No. 24, 1-20 (1953), German.
This paper describes initial results on the inhibition of enzyme reactions
by quartz dusts. It was found that potato phosphatase was adsorbed on quartz dust
to an extent depending on the specific surface of the quartz, but that in the adsorb
ed state the enzyme was still nearly 100% active. Aluminum phosphate and alum
inum silicate also adsorbed the enzyme. A search for phosphatase in a fresh sample
of silicotic lung tissue gave negative results. The work will be continued with other
enzymes.
-- Cond. from Bull. Hyg.
w**
I'^9 Early Diagnosis of Asbestosis by Enlarged Radiographs. J. Krausler and R. Seyss. Z. UnfaUmed. u. Berufskrankh, 47, 59-64 (Mar. 15, 1954). German.
After a brief description of asbestosis and the changes in the lung tissue
in the early stages, the authors describe a radiographic technique with a fine focus. Of 1 6 asbestos worners, with 1 to 18 year's exposure, eight showed changes in the lung tissue with the enlargement technique; two of these showed no change by
normal technique, and in the other six cases the degree of change shown was
minimal.
-- Cond. from Bull. Hyg.
* `^0 Pneumoconiosis in a Feldspar Worker. W. Rotter and H. Gartner.
Zentraibi, Arbeitsmed. u. Arbeitsschutz 4, 35-40 (Mar. 1954). German,
The authors describe a fatal case of lung disease in a feldspar worker, which they regard as modified silicosis. The dust contained 27. 1% potassium
j 31.
Industrial Hygiene Digest Index
1954
iracosis in smoky city
299
Anthrax bacteria, air-sampling prevention in tanneries
1074 828
Anticholinesterases action of phosphorus compounds poisoning and respiratory failure symposium (see also insecticid es, Cholinesterase )
88? 888
63 642 886
Antimony trioxide toxicity
511
Antiseptics, disinfectants. fungicides, and sterilization (bk. rev. )
356
Ars enic azard in mines
poisoning JBAL treatment and heart disease
613 755 1252 271
Arthritis, rheumatoid x-ray appearances
180, 181
Artificial respiration (see Resuscitation)
Atomic bomb attack burns psychological aspects 83, first aid radiologist's role (see also Civil defense)
319 1047
1159 87
Atomic power project, health center public health aspects
*
Autoradiography in radium detection
918 435
803
Bacteriological safety
28
BAL therapy
cobalt poisoning
874
lead poisoning 617, 1252, 1257
Baritosis
304
Barium chloride, poisoning
512
Benzene
'
data sheet
determination in air
metabolism
poisoning
blood coagulation 1271,
- lymphoid lesions in
serum lipase in
768 561 769
1272 1008
767
Asbestos
dust in lungs
`1021,
and mica pneumoconiosis
in urine
warts
1022 550 905 26 2
Asbestosis early diagnosis and pseudo-asbestosis bodies
1299 73
ospheric turbulence studies
934
Benzene hexachloride detection in vegetables determination in air determination in foods hazard in paint poisoning, chronic sensitivity to toxicity
674 1165 1133 1014
166 536 537
Benzidine
.
and derivatives, determiration564
test for hazard
1275
naphthylamines and tumors 772
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Industrial Krgiene Digest Decennial Index
1945-1^=4
A -?eric (cont. ) in :3*o air (1952] ! 1 34 lr: oxide
detoxication by fluoride* (19451 905
effect an rat tissue (1946] 417 exposure in industry (1953) 809 tolerance (rats) (1946) 416
A -sine m mnustry (1948) 977 mechanism of action (1947) 1173 poisoning (1947) 224, 858;
(1948) 84 1; (1950) 573, 574; (1952) 33, 35 from algae (1953) 1041 and BAL (1950) 1039 irom boiler cleaning (1951) 844,
! 984
\ easels) (1946) 637; (1950) 459, I 324. 325, 1232; (1951) 262 ( electrocardiographic changes ! (1951) 985 1 fatal case (1952) 34; (1953) 39 i prevention (1953) 1042 from scaling (1950) 458 ' smelting industry (1950) 1157, ; 1L5S ! toxicity (1947) 1114
' arterial oxvgen saturation ^termination (1952) 502
'= Arthritis ; ar.c compensation (1950) 1036
criteria for compensation claims . (1946) 1267
-0 industry (1952) 1176 . Marie 5 turn pel's (1950) 1037
osteo, from pressure (1949) 790, 791
rbeumetoid, and pneumoconiosis (1954) 180, 181
sequel of trauma wrist (1950) 40
Artificial circulation (1947) 1367 (see also Resuscitation)
A rtificial kidney sevelopment of (1949) 143
Artificial respiration (see also Re suscitation)
devices for (1945) 147
A sbestos ci.rucai study (1953) 284 corns (1945) 68 dust control (1947) 327 dust in lungs (1954) 1021, 1022
"feet on tissue cultures (1948) 77 "S cancer from (1953) 605 and mica pneumoconiosis
(1954) 550
A sbestos (cont.)
possible substitute (1945) 1239
and skin granuloma (1950) 1146
in urine (1954) 905
warts (1954) 262
Asbestosis (1948) 278; (1950) 357, 1053; (1952) 674
aluminum prophylaxis (animals) (1947) 234
bodies, electron microscopy (1951) 1142
and cancer (1945) 69; 1949) 867; (1952) 1009
cases (1953) 79 necropsied (1950) 36
control (1952) 83 diagnosis (1947) 1046: (1954) 1299 experimental (1945) 436; (1951) 192;
(1952) 219, 436 in fibro-cement industry (1952) 84 in Finland (1947) 1045 French report (1948) 148 pathology (1953) 78, 604 in pipe-covering operations
(1946) 353 pseudo-bodies (1952) 438; (1954) 73 and sarcoidosis (1947) 407 in Slovakia (1951)83 study of (1951) 598
miniature films (1953) 496 and tuberculosis (1948) 888
A spergillosis (1946) 142
Asphvxia (see also Resuscitation) treatment of (1946) 1259
A sohvxiation in a diving bell (1951) 580
Asthma in industry (19S2) 625 bronchial (1952) 958
Atabrine dermatitis (1947) 713 workers, "blue haleos" in
(1947) 1324
Athlete's loot (see also Dermatophytoses and Fungus diseases)
cotton hose as vehicle (1945) 762 prevention (1949) 1007 treatment (1946) 324, 505, 1036
Atmospheric conditions conducive to efficiency (1945) 621
Atmospheric contamination pollution (see Air pollution) symposium (1950) 391
.
Atmospheric diffusion measurement (1952) 1244
Atmospheric pollution (see Air pollution)
Atmospheric turbulence (bk, rev.)
(1951) 14
'
measurement (1953) 643 studies (1954) 934
Atomic energy (1946) 109.1, 1092; (see also Radiation)
biological applications (1946)570 chemical problems in (1951) 292 Commission medical program
(1949) 127 constructive use (bk, rev.)
(1950) 1027 economics (1948) 88 employee orientation (1952) 376 hazards (1946) 36, 988; (1947) 534,
995, 997; (1950) 612 control, automatic (1951) 750 control of (bk. rev.) (1950) 1027,
1028 radiation-(see Radiation) in industry (1947) 298, 883;
(1949) 128 insurance (1947) 1260;(1950) 1207,
1208 international control (bk. rev.)
(1947) 142 medical aspects (1946) 301;
(1947) 996, 1119 neutron health monitoring (1949) 34 1
(1950) 225 physiologic effects (1947) 297 project, health center (1954) 918 protection from radiation (1946) 607 public health aspects (1954) 435 safeguards (1947) 326 slow tissue activation by neutrons
(1946) 231 utilization of (1947) 1349 ventilation (1952) 227
Atomic research alleged injury to workers (1947) 999
Atomic warfare atomic bomb (bk. rev.) (1949) 809 biological aspects (1946) 1042,
1223 burns (1950) 968; (1951) 615;
(1952) 790: (1 954) 319 _ casualties care (1951) 384, 898;
(1953) 747 damage and protection (1950) 500 defense, civil (1951) 94
role of doctor (1950) 1065 disaster plan (1948) 689 effects (1947) 174, 994, 995, 1 119,
1120; (1948) 1101; (1949) 213, 339, 492, 494; (195 1) 98 on blood ( 1950) 2 16, 217 , 2 18. 219; (1953) 619
-7-
' '>* dustrial Hygiene Digest
INDUSTRIAL HEALTH NEWS
LITERATURE ABSTRACTS
MEDICAL ENGINEERING CHEMICAL TOXICOLOGICAL LEGAL.. decision* And ttvoda
~~J) - c 6 m w i ft L I//4 "/ _
-sS
INDUSTRIAL HYGIENE FOUNDATION
MELLON INSTITUTE
4400 FIFTH AVENUE
PITTSBURGH 13, PA.
Industrial Hygiene Digest
January, 1954
months than after one month. With the middle grades then were two types of reaction, possibly due to agglomerations and discrete particles respec tively. The decrease in proliferation from the finest may be due either to elimination after solution or removal by microphages. Experiments are being continued.
71 Occupational Lung Damage in Ships' Repairers. L. Dun^er, M. Sanger, & D. T. J. Bagnall. Brit. J. Radiol. 26, 590-594 (Nov. 1953).
Occupational lung damage in ships' repairers ("boiler-makers"), due to inhaled dust and/or fumes has been described for the first time. Analysis of the materials and the dusts to which these men are exposed while at work revealed the presence of free silica and iron compounds. Two broad groups are described, namely those with definite radiological changes and those without. Each group may be subdivided into those with severe symptoms, especially dyspnea resulting in incapacity, and those without symptoms. Post-mortem findings of severe emphysema with slight pneumoconiosis are reported in two men belonging to the group, with extreme incapacity in the absence of radiological lesions.
-- Authors' summary
72 Asthma and Silicosis, Queries and Minor Notes, J. Am. Med. Assn. 153, 1327 (Dec, 5, 1953).
Asthma occurring for the first time in a 52-year-old person can
be aggravated by silicosis. The type of dyspnea caused primarily by
silicosis is due to damage of the lung parenchyma and to emphysema. In
some persons with silicosis, bronchospasm is induced secondarily. It
should also be remembered that a 52-year-old man may have allergic
infections or cardiac asthma for the first time. If the patient in question
has true asthmatic episodes (relieved by epinephrine or aminophylline),
a search for other causative factors should be made by a series of observa
tions such as examination of the sputum for eosinophils and neutrophils,
skin tests, and examination for hypertensive, coronary, or syphilitic
heart disease.
'
73 Asbestosis Bodies and Pseudo-Asbestosis Bodies. J. Ruttner. Schweiz, Z. Allgem. Pathol, u. Bakteriol. 15, 628-631 (1952), German.
The literature on asbestosis bodies is reviewed. Similar products
were found by the author in a lung which only contained carborundum and
graphite; the bodies were formed around plates and needles of carborundum.
The protein and iron which form the bulk of the "bodies" must come from
the lung tissues and not from the mineral matter of the dust. Similar
bodies could also be produced in vitro but they have not so far been found
in animal experiments.
-- Bull. Hyg.
r'2, Hvgiene Digest
March, 1954
. the eruption, especially whether it coincides with the work period; ,..d (4) character of the eruption, with consideration of possible occupa,_>nal aggravation of a non-occupational dermatitis. The limitations of .-,e significance of patch tests are discussed. The problem of fungous .lections in relation to occupational dermatitis is considered. Some cases : dermatitis require study, even by an experienced dermatologist, before
etiological diagnosis can be made.
:cuaational Skin Disease, Public Health Service Publ, No, 306, . L Dept, of Health, Education, and Welfare, and Controlling Chemical .azards, Series No. 10. U. S, Dept. Labor, Bureau of Labor Standards. .5 pp. (1953). For sale by Supt, of Documents, U. S. Govt, Printing office, Washington 25, D. C. 10 cents.
This brief pamphlet presents the essentials about occupational skin . iease--direct and indirect causes, and prevention and treatment on the ire at the employer and the worker.
. ^oestos Warts and Other Dermatoses in Workers with Lagging Materials. "7 .''"arris,"" Rass. med, ind7 22, )Vi 7 (Jan. - Feb. 1953). Italian.
The author has investigated cases of warts on the hands of 29 workers
.'.a lagging materials, including asbestos cord which is wound around pipes,
jr.ous asbestos-containing slabs, and mixtures of asbestos and cement
j be molded to the shape of the tank or other object to be insulated. One to
,ur warts were found in every case. They are due to asbestos fibers which
penetrate into the epidermis and become lodged in the corium or true skin.
The epidermis shows acanthosis (thickening of the prickle-cell layer) and
hyperkeratosis (increased horny tissue) and the corium shows a granulo
matous type of reaction with the appearance of giant cells in some cases.
Exudative dermatitis may also be present. This condition is attributed to
the combined action of the hygroscopic and alkaline cement and the irritating
asbestos fibers. The gross and microscopic appearances of the lesions are
illustrated.
-- Cond. from Bull. Hyg.
Dermatitis Due to Pancreas. S, Tara, G. Bouwens, A. Cavigneaux, and V. Deiplace, Arch, maladies profess, 14, 44-46 (1953). French.
Two cases are reported of workers employed ir a pharmacological laboratory who experienced skin trouble when they manipulated pancreas preparations. Erosion of the skin with bleeding is a feature of this form of dermatitis. Similarly to papaya latex and pineapple juice, enzymes from
pancreas exert a solvent action on the skin. -- Cond. from Bull. Hyg.
Industria! Hygiene Digest
August, 1954
upon the PH. From albumin solutions having a concentration comparable with olasma only about one-tenth of the available adsorption sites on a quartz surface are filled at PH 7.4. The adsorption of proteins upon the quartz surface is not considered to be an important aspect of the silicosis problem.
-- Authors' conclusions
905 The Presence of Asbestos Fibers in Urine of Workers Exposed to Asbestos Hazard, V. Wyss. Rass. med. ind. 2, 55-56 (1953). Italian.
In urinary sediment of two asbestos workers asbestos fibers were seen;
the same finding was detected in urine of two female patients suffering from as-
bestosis, who had left their work seven years before.
-- Biol. Absts.
PHYSICAL ASPECTS OF THE ENVIRONMENT
'Oo dome Practical Aspects of Industrial Noise Measurement. L. J. Proulx. Arch. Ind. Hyg. & Occ. Med. _9, 496-502 (June 1954).
Some of the instrumentation problems faced by an engineer who must evaluate industrial noise environments are discussed. An array of equipment which includes a sound level meter, octave band analyzer, tape recorder, dynamic microphone, audio oscillator, vacuum tube voltmeter, high-fidelity crystal head phones, cathode ray oscilloscope, and a good quality loudspeaker is described. The use of the tape recorder and oscilloscope for measuring impact noises is given particular attention. Various calibration checks are described.
^07 The Locus of Short Duration Auditory Fatigue or "Adaptation." J, D. Harris and Anita L, Rawnsley. J. Expti. Psychol. 46^, 457-461 (1953).
Auditory adaptation, defined as a reversible shift in threshold following very mild acoustic stimulation, was distinguished from true auditory fatigue by four criteria; (1) the non-cumulative effect of stimulus duration; (2) the temporal course of return to normal threshold following stimulation; (3) the relative fre quency region of maximum threshold shift following pure tone stimulation; and (4) the shape of the curve of loudness (recruitment.) This experiment sought to throw light upon where, in the auditory system, adaptation occurs. By the tech nique of simultaneous binaural loudness balancing between one normal ear under going a threshold shift of a preceding adapting stimulus, it was possible to demon* s'rate an accelerated growth of recruitment in the adapted ear. The intimate
29.
sen: I H\'ietie Digest
September, 1954
foremost in disabling silicosis, emphysema stands out as the cause. Emphysema a,one w.th its shortness of breath may lead to a condition simulating asthma and -is no specific association with silicosis. In a silicotic patient with emphysema, o coexisting ^ronchitis may exaggerate the emphysema and thus further the total c.3tur_ances. On an organic basis, exposure to silica will not be more harmful to an asthmatic person than to any other worker. On a psychogenic basis, the asth matic person is prone to react unfavorably to any dust and therefore on an emotion al oasis may not get along well in the presence of silica dust. The correspondent is referred to the report of the Third Symposium on Silicosis at Saranac Lake, '37 for a fuller discussion.
D.itrlbution of Mineral Particles and Fibers in the Lung after Exposure to Asbestos C mt, J. F. Knox and J, Beattie. Arch. Ind. Hyg. & Occ. Med. U3, 30-36 (Ja.y 1954).
The particle-size distributions in the incombustible and acid-insoluble residues from the lungs of 27 persons who had been exposed to asbestos dust were cctermvned. The number of particles with greatest lengths in excess of 26 microns *'as considerable up to the eighth year after the last exposure to asbestos dust and `-..or. sharply fell. The number of particles within the size ranges of five microns ir.d less and between five and 15 microns remained constant over a very long period :: 'lose cases which showed no sign of asbestosis or minimal fibrotic change. The joaes of severe asbestosis showed a significant rise in the numbers of such particles.
It is considered that the mechanism which is concerned with the production o: r.uman asbestosis is not the same as that which is responsible for the production of ninestotic changes in experimental animals exposed to high concentrations of asbes os dust. The appearance of such changes seems to be related to the breakdown of asoestosis bodies which may liberate some fibrogenic agent.
- - Authors* summary
Mineral Content of the Lungs after Exposure to Asbestos Dust. J. F, Knox and J. Beattie. Arch. Ind, Hyg. & Occ. Med. _1_0, 23-29 (July 1954).
The mineral content of the lung parenchyma, the lung hilar region, and
"".e tissues of the pleural and subpleural regions of the lung has been determined in
lungs from 27 workers in the asbestos-textile industry. The exposure time varied
from five to 33 years, and the time interval between the last exposure to dust and
Heath (survival time) was from less than one year to 21 years. There was an indica-
I'On that the mineral material found in the lungs Increased in amount as the exposure
t-me lengthened. The amount so accumulated varied considerably from person to
person. As the survival time increased, the mineral content of the Lung tended to
decline but again at a very variable rate. The severity of the asbestotic lesions
the lungs found at death was related not to the mineral content but to the sum of
* exposure and survival times.
-- Authors' summary
H.dStrlal Hygiene Digest
December, 1954
ions on the surface Irregularities produced by removal of alumina and other im
purities. The presence of these ions enables the silica surface to attract a greater
number of hydroxyl ions from the solvent medium, with the subsequent formation
of highly soluble silicic acid.
-- Cond. from authors' conclusions
;97 Physicochemical Studies on Dusts. 8. Some Sorption Properties of Siliceous Dusts. J. G. Gibb and P. D. Ritchie. J. Appl. Chem. 4, 483-487 (Sept. 1954),
Rock crystal, Lochaline sand, and vitreous silica (Vitreosil) dusts all
show reduced affinity for a dyestuff cation on removal of the disturbed outer layer
from the particle surfaces. This layer of amorphous silica is therefore more re
active than the .underlying core in sorption processes, just as in solution processes.
In the case of vitreous silica, there is probably a physical difference between the
outer amorphous layer and the nominally amorphous core, such as a more open
structure. Heat treatment and repeated acid extraction have the same effect in
both sorption and solution experiments. Alteration of the surface is probably
responsible in both cases.
-- Cond. from authors' conclusions
198 The Effect of Quartz Dust and Aluminum Phosphate on Certain Enzymes.* * B, Helferich and Erika Schmitz. Beitr, Silikose-Forsch. No. 24, 1-20 (1953). German.
This paper describes initial results on the inhibition of enzyme reactions
by quartz dusts. It was found that potato phosphatase was adsorbed on quartz dust
to an extent depending on the specific surface of the quartz, but that in the adsorb
ed state the enzyme was still nearly 100% active. Aluminum phosphate and alum
inum silicate also adsorbed the enzyme. A search for phosphatase in a fresh sample
of silicotic lung tissue gave negative results. The work will be continued with other
enzymes.
-- Cond. from Bull. Hyg.
*99 Early Diagnosis of Asbestosis by Enlarged Radiographs. J. Krausler and R. beyss. Z. Unfalimed, u. Berufskrankh. 47, 59-64 (Mar. 15, 1954). German.
After a brief description of asbestosis and the changes in the lung tissue in the early stages, the authors describe a radiographic technique with a fine focus. Of 16 asbestos workers, with 1 to 18 year's exposure, eight showed changes
in the lung tissue with the enlargement technique; two of these showed no change by
normal technique, and in the other six cases the degree of change shown was
minimal.
-- Cond. from Bull. Hyg.
Pneumoconiosis in a Feldspar Worker. W. Rotter and H. Gartner. Zentralbi. Arbeitsmed. u, Arbeitsschutz 4, 35-40 (Mar. 1954). German,
The authors describe a fatal case of lung disease in a feldspar worker, which they regard as modified silicosis. The dust contained 27. 1% potassium
Industrial Hygiene Digest Index
1954
. iracosis in smoky city
299
Anthrax bacteria, air-sampling prevention in tanneries
1074 828
Anticholinesterases action of phosphorus compounds poisoning and respiratory failure symposium (see also Iasecticid es, Cholinesterase)
881888
63 642 886
Antimony trioxide toxicity
511
Antiseptics, disinfectants. fungicides, and sterilization (bk. rev. )
356
Arsenic azard in mines
poisoning BAL treatment and heart disease
613 755 1252 271
Arthritis, rheumatoid x-ray appearances
180,, 181
Artificial respiration (see Resuscitation)
Atomic bomb attack
burns
319
psychological aspects 83, 1047
first aid.
1159
radiologist's role
87
(see also Civil defense)
Atomic power project, health center public health aspects
918 435
Autoradiography in radium detection
803
Bacteriological safety
28
BAL therapy
cobalt poisoning
874
lead poisoning 617, 1252, 1257
Baritosis
304
Barium chloride, poisoning
512
Benzene
'
data sheet
determination in air
metabolism
- poisoning
blood coagulation 1271,
- lymphoid lesions in
serum lipase in
768 561 769
1272 1008
767
Asbestos
-
dust in lungs
`1021,
and mica pneumoconiosis
in urine
warts
1022 550 905 262
Asbestosis early diagnosis and pseudo-asbestosis bodies
1299 73
. ospheric turbulence studies
934
Benzene hexachloride detection in vegetables determination in air determination in foods hazard in paint poisoning, chronic sensitivity to toxicity
674 1165 1133 1014
166 536 537
Benzidine
.
and derivatives, determinations64
test for hazard
1275
naphthylamines and tumors 772
1
Industrial Hygiene Digest Decennial Index
:45-: ^4
A rservic (cont.) :n town air (1952) 1134 trioxide
detoxication by fluorides (1945) 905
effect on rat tissue (1946) 417 exposure in industry (1953) 809 tolerance (rats) (1946) 416
A - sine m industry (1948) 977 mechanism of action (1947) 1173 poisoning (1947) 224, 858:
(1948) 841; (1950) 573, 574; (1952) 33. 35 from algae (1953) 1041 and BAL (1950) 1039 from boiler cleaning (1951) 844, 984 easels) (1946) 637; (1950) 459, I 824, 825, 1282; (1951) 262 ( electrocardiographic changes i (1951) 985 < fatal case (1952) 34; (1953) 39 i prevention (1953) 1042 from sealing (1950) 458 * smelting industry (1950) 1157, ; 1158 ! toxicity (1947) 1114
' -rterial oxvgen saturation ^termination (1952) 502
: Arthritis : ar.s compensation (1950) 1036
criteria for compensation claims (1946) 1267
n industry (1952) 1176 j 'lane stum pel's (1950) 1037
osteo, from pressure (1949) 790, j 791 ' rheumetoid, and pneumoconiosis ' (1954) 180, 181 . sequel of trauma wrist (1950) 40
t Artificial circulation (1947) 1367 { (see also Resuscitation)
A rtifictal kidney development oi (1949) 143
Artificial respiration (see also Resuscitation)
devices for (1945) 147
A she sto s ci.nical study (1953) 284 eorns (1945) 68 ' 9ust control (1947) 327 dust in lungs (1954) 1021, 1022
"set on tissue cultures (1948) 77 ng cancer from (1953) 605 *hd mica pneumoconiosis
(1954) 550
Asbestos (cont.) possible substitute (1945) 1239 and skin granuloma (1950) 1146 in urine (1954) 905 warts (1954) 262
Asbestosis (1948) 278: (1950) 357, 1053; (1952) 674
aluminum prophylaxis (animals) (1947) 234
bodies, electron microscopy (1951) 1142
and cancer (1945) 69; (1949) 867; (1952) 1009
eases (1953) 79 necropsied (1950) 36
control (1952) 83 diagnosis (1947) 1046: (1954) 1299 experimental (1945) 436; (1951) 192;
(1952) 219. 436 in fibro-cement industry (1952) 84 in Finland (1947) 1045 French report (1948) 148 pathology (1953) 73, 604 in pipe>covering operations
(1946) 353 pseudo-bodies (1952) 438: (1954) 73 and sarcoidosis (1947) 407 in Slovakia (1951)88 study of (1951) 598
miniature film* (1953) 496 and tuberculosis (1948) 883
A soergillosis (1946) 142
Asphyxia (see also Resuscitation) treatment of (1946) 1259
A sohvxiation in a diving bell (1951) 580
Asthma in industry (19S2) 625 bronchial (1952) 953
Atabrine dermatitis (1947) 713 workers, "blue haleos" in
(1947) 1324
Athlete's foot (see also Dermatopeytoses and Fungus diseases)
cotton hose as vehicle (1945) 762 prevention (1949) 1007 treatment (1946) 324, 505, 1036
Atmospheric conditions conducive co efficiency (1945) 621
Atmospheric contamination pollution (see Air pollution) symposium (1950) 391
.
Atmospheric diffusion measurement (1952) 1244
Atmospheric pollution (see Air pollution)
Atmospheric turbulence (bk. rev.) (1951) 14
measurement (1953) 643 studies (1954) 9 34
Atomic energy (1946) 1091, 1092;
(see also Radiation)
biological applications (1946) 570
chemical problems in (1951) 292
Commission medical program
(1949)127
constructive use (bk. rev.)
(1950) 1027
economics (1948) 88
employee orientation (1952) 376
hazards (1946) 36, 988; (1947) 534,
995, 997; (1950) 612
control, automatic (1951) 750
control of (bk. rev.) (1950) 1027,
1023
radiation-(see Radiation)
in industry (1947) 298. 883;
' (1949) 123
insurance (1947) 1260; (1950) 1207,
1203
'
international control (bk. rev.)
(1947) 142
medical aspects (1946) 301;
(1947) 996, 1119
neutron health monitoring (1949) 341
(1950) 225
physiologic effects (1947) 297
project, health center (1954) 918
protection from radiation (1946) 607
public health ajpects (1954) 435
safeguards (1947) 326
slow tissue activation by neutrons
(1946) 231 utilization of (1947) 1349
ventilation (1952) 227
Atomic research alleged injury to workers (1947) 999
Atomic warfare atomic bomb (bk. rev.) (1949) 809 biological aspects (1946) 1042,
1223 burns (1950) 968; (1951) 615:
(1952) 790; (1 954) 319 _ casualties care (195 1) 384, 898;
(1953) 747 damage and protection (1950) 500 defense, civil (1951) 94
role of doctor (1950) 1065 disaster plan (1948) 639 effects (1947) 174, 994, 995, 1119,
1120; (1948) 1101; (1949) 2 13 , 339, 492, 494; (1951) 98 on blood (1950) 216, 217, 218, 219; ( 1953) 619