Document evdz3g8253oR9e0Xv7mZ11ebq
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Russell White <whiter@api.org> Friday, November 17, 20062:32 PM (GMT) BenzConsort-OC@listserve.api.org; BenzConsort-TC@listserve.api.org Howard Feldman <Feldman@api.org>; John Wagner <Wagner@api.org>; Robin Tillery <tilleryr@api.org> Shanghai Health Study - REMINDER - Conference call November 17, 1:30 PM EST ole2.bmp; SHS Oversight Committee Call Nov 9 2006.doc; DRAFT Spreadsheet for proposed JCML budget 11-13-06.xls
Attached are two items for your review before the call; the minutes from the last call from Jennifer and a budget spreadsheet to help guide discussion of Dr. Irons' new proposal. Please note, we do not yet have estimates from Dr. Wong, Fudan University, and other contractors at this time. Included in the spreadsheets are Dr. Irons' proposed budgets and my unofficial estimates of other contracts.
Draft agenda;
1) Establish quorum and note taker - Patsy 2) Review antitrust guidelines - Mark 3) Dr. Irons' grant requests - Jennifer 4) Other contracts - Russ 5) Planning for the meeting in December - Patsy/Zach/Trisha
Meeting times - Agenda items - Dinner 6) Other business/next call - Patsy
Conference call: Toll Free Dial-In Number: (866) 443-0059 International Dial-In: (770) 765-9147 Enter this code at the prompt: 202 682 8344#
Operator-Assisted Service: Toll-Free Dial-In Number: (800) 572-9844 International Dial-In Number: (706) 643-1733 Call Participant Functions *0 Operator assistance
*6 Mute your own line
SHS Oversight Committee Call Nov 9 2006.doc DRAFT Spreadsheet for proposed JCML budget 11-13-06.xls
~ Picture (Metafile)
SH ELL-MCCLU RG-053625
AB
1
2
3 4 Cost Centers
Project #
5
6 Income
7
8 Cost Centers 9 UCHSC + JCML
X8105
10 Irons-Field Expense
X8106
11 Applied Health Sciences
X8107
12 Fudan University
X8108
13 Scientific & Ethics Panels X8109
14 Communications
X8103
15 Outside Legal Counsel
X8104
16 QAJQC Support
X8110
17 API Administrative
X8100
18 Exposure Assessment
x8111
19 Contingency
20
21 Total Expenses
22 23 Fund Balance
24
25
26
C Inception
Thru
December 2004
D
Actuals Jan - Dec
2005
Benzene Health Research Consortium Executive Summary
3Q06 Financial Report
E Original Projected
Jan - Dec 2006
F Original Projected
Jan - Dec 2007
G
$ 16,765,693 $ 5,206,657 $ 2,826,039 $ 1,535,748
H
Original 2007 EOY projection
26,401,122
10,137,850 788,486
1,391,014 124,090 181,713 294,161 64,529
-
856,208
-
104,473
3,624,030
262,000
548,720
4,007
76,176
-
33,706
-
170,475
-
51,918
4,000,000 262,000 547,953 94,472 92,549 1,946 31,244 16,667 163,500 40,000
-
570,889 100,942 502,311
80,704 96,726
1,946 31,242 16,667 225,450 69,000
-
13,778,460 990,282
18,332,769 1,413,428 2,989,998 303,273 447,165 298,053 160,721 33,333 1,415,633 109,000 156,391
$ 13,942,525 $ 4,771,033 $ 5,250,331 $ 1,695,877
$ 25,659,765
$ 2,823,169 $ 3,298,247 $ 873,955 $ 713,826
IJ
FINISH 2007
Jan - Dec
7,299,004
-
548,000 95,000 95,000
-
33,000
-
175,000 69,000
-
$ 8,314,004
All numbers in yellow are just my estimates - RDW
Page 1 of 19
&[DATE]
SH ELL-MCCLU RG-053626
K LM
N
1
2
FINISH
TRANSITION
3 2008 4 Jan - Dec
2007 Jan - Dec
5
6
7
8
9 - 8,539,004
10 -
-
11 503,000 12 65,000
548,000 95,000
13 95,000
95,000
14 -
-
15 35,000
33,000
16 -
-
17 180,000
175,000
18 -
69,000
19 -
-
20
21
$ 878,000
$ 9,554,004
22
23
24
25 26
Benzene Health Research Consortium Executive Summary
3Q06 Financial Report
0 P Q RS T UV
W
TRANSITION 2008
Jan - Dec
Original 2007 EOY projection
FINISH 2008 EOY projection
TRANSITION 2008 EOY projection
POST STUDY 2008-2009
26,401,122
170,000 $
-
503,000 65,000 95,000
-
35,000
-
180,000
-
878,000
18,332,769 1,413,428 2,989,998 303,273 447,165 298,053 160,721 33,333 1,415,633 109,000 156,391
$ 25,659,765
$-
25,060,884 1,312,486 3,538,687 382,569 540,439 296,107 197,479 16,667 1,545,183 109,000 156,391
$ 33,155,892
$ (7,496,127)
26,300,884 1,312,486 3,538,687 382,569 540,439 296,107 197,479 16,667 1,545,183 109,000 156,391
$ 34,395,892 $
$ (8,736,127)
600,000
-
600,000
-681466.0909
-794193.3636
Page 2 of 19
&[DATE]
SH ELL-MCCLU RG-053627
AB
1 2 Expenditures:
3 4 5 6 7
8 9 10 11 12 13 14 15 16 17 18
19 20 21 22 23 24 25 26 27
28 29 30 31
32 33 34 35 36 Total Expenditures: 37 Total Grant Funding:
38 39 Other Costs: 40
41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
Personnel:
Total Personnel: Operating Expenses
Total Operating Expenses: Sub Contracts:
Total Sub Contracts: Travel: Equipment: Total Equipment: Indirect Costs: Total Indirect Costs:
Field Expenses
C
D
E
FG
H
UCHSCGRANT Accumulative Actuals
to date 06/30/06
Projected for 07/01106 to 12/31106
Projected for 011112007 to 06/30/2007
Projected totals 07/0112007
Projected for 07/0112007 to
12/3112007
Personnel at UCHSC: $ Personnel at JCML $ Other: $ $
Expendable Supplies: $ Non-capital Equipment: $
Services $ Maintenance: $ ME feasibility Study $ Contingency: $
UCHSC Expenses JCML Expenses $
Fudan University (1) $ IPHSC (2) $
SMCDCP (3) $ EMBSI (5) $
Children's Hospital (Cincinnati) (6) $ Histology (7) $ $ $
Capital Equipment: $ Shippinglimportation
$
Overhead: Other:
$
$ $ $
$
2,402,457
-
3,900
2,406,357
$ $ $ $
1,353,110 156,787 212,557 51,288 8,160 43,330
$ $ $ $ $ $
1,825,231 $
5,121,580
170,077
153,004
2,515,754
336,834
-
8,297,250
9,218
$ $ $ $ $ $ $ $
1,383,491 1,383,491
$ $ $
1,129,984 $
1,129,984 $ 15,051,530 $ 15,761,880 $
1,181,486 $
245,804
-
245,804
$ $ $ $
-$ -$ -$ -$ -$ -$
$ $ 160,780 $
-
1,229,168
500
$ $ $ $ $ $ $ $
-$ -$ -$
105,842 $
105,842 $ 1,742,094 $ 2,000,000 $
235,083
664,320
-
899,403
$
-
49,500 2,066,750 2,116,250 $
252,000
-
730,550
48,562
3,000
1,034,112
-
$ $
-$
73,992
73,992 $ 4,123,757 $
570,889 $
131,000 $
100,942 $
$ $
3,551,564 $
$ $ $ $ $ $
$ $ 4,102,261 $
10,560,530 9,718
$ $ $ $ $ $ $ $
$ $ 1,383,491 $
1,309,818 20,917,381 18,332,769
$ $ $ $
1,413,428
246,837 664,320
911,157
-
60,000 1,345,200 1,405,200
-
730,550 48,562
-
779,112
-
-
79,778
-
79,778 3,175,247
&[DATE]
SH ELL-MCCLU RG-053628
I
Projected totals
1 12/3112007
2
3
4
5
6 7$
4,462,721
8
9
10
11
12
13
14
15
16
17
18 $
5,507,461
19
20
21
22
23
24
25 26 $
11,339,642
27 $
9,718
28
29
30
31 $
1,383,491
32
33
34
35 $
1,389,596
36 $
24,092,628
37 $
(5,759,859)
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
J
K L M N0
P
1570872 1047248
523624
3141744 2094496
523624 5759864
1909053.818 1272702.545 636351.2727
3818107.636 2545405.091 636351.2727
6999864
2072690.182 1381793.455 690896.7273
4145380.364 2763586.909 690896.7273
7599864
&[DAT
SH ELL-MCCLU RG-053629
QR
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
&[DATE]
SH ELL-MCCLU RG-053630
AB
1 2 Expenditures: 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 Total Expenditures: 38 Total Grant Funding: 39 40 Other Costs: 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59
Personnel:
Total Personnel: Operating Expenses
Total Operating Expenses: Sub Contracts:
Total Sub Contracts: Travel: Equipment: Total Equipment: Indirect Costs: Total Indirect Costs:
Field Expenses Post Study Work
C
D
E
FG
H
UCHSCGRANT Accumulative Actuals
to date 06/30/06
Projected for 07/01106 to 12/31106
Projected for 011112007 to 06/30/2007
Projected totals 07/0112007
Projected for 07/0112007 to
12/3112007
Personnel at UCHSC: $ Personnel at JCML $ Other: $ $
Expendable Supplies: $
Non-capital Equipment: $ Services $
Maintenance: $ ME feasibility Study $
Contingency: $
UCHSC Expenses JCML Expenses $
Fudan University (1) $ IPHSC (2) $
SMCDCP (3) $ EMBSI (5) $
Children's Hospital (Cincinnati) (6) $ Histology (7) $ $
$
Capital Equipment: $ Shippinglimportation
$
Overhead: Other:
$
$ $ $
$
2,402,457
-
3,900
2,406,357
$ $ $ $
1,353,110 156,787 212,557 51,288 8,160 43,330
$ $ $ $ $ $
1,825,231 $
5,121,580 170,077 153,004
2,515,754 336,834
-
8,297,250
$ $ $ $ $ $ $
9,218 $
1,383,491 1,383,491
$ $ $
1,129,984 $
1,129,984 $ 15,051,530 $ 15,761,880 $
1,181,486 $
245,804
-
245,804
$ $ $ $
-$ -$ -$ -$ -$ -$
$ $ 160,780 $
-
1,229,168
$ $ $ $ $ $ $
500 $
-$ -$ -$
105,842 $
105,842 $ 1,742,094 $ 2,000,000 $
235,083
664,320
-
899,403
$
-
49,500 2,066,750 2,116,250 $
252,000
-
730,550
48,562
3,000
1,034,112
$
-$
-$
73,992
73,992 4,123,757
570,889
$ $ $
131,000 :Ii
100,942 $
$ $
3,551,564 $
$ $ $ $ $ $
4,102,261
$ $ $
10,560,530
$ $ $ $ $ $ $
9,718 $
1,383,491
$ $ $
1,309,818 20,917,381 18,332,769
$ $ $ $
1,413,428
246,837 1,064,320
1,311,157
-
60,000 2,185,200 2,245,200
-
730,550 48,562
-
779,112
-
-
79,778
-
79,778 4,415,247
RrnATFl
SH ELL-MCCLU RG-053631
I
Projected totals
1 12/3112007
2
3
4
5
6 7$
4,862,721
8 9
10
11
12
13
14
15
16
17
18 $
6,347,461
19
20
21
22
23
24 25
26 $
11,339,642
27
28 $
9,718
29
30 31
32 $
1,383,491
33
34
35
36 $
1,389,596
37 $
25,332,628
38 $
(6,999,859)
39 40
41
42 $
600,000
43 $
(7,599,859)
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
J
K
L MN
0
P
RrnATFl
SH ELL-MCCLU RG-053632
Q
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59
RS
&[DATE]
SH ELL-MCCLU RG-053633
A
60
61 62 63 64 65 66 67 68 69 70
B
C
D
E
FG
H
&[DATE]
SH ELL-MCCLU RG-053634
I
60
61 62 63 64 65 66 67 68 69 70
J
K
L MN
0
p
&[DATE]
SH ELL-MCCLU RG-053635
A Bc DE FG H
J K LM No
2
3 able I. UC DHSC PI n A- Study Comple ion
4
5
,-,urr nI'y unae
ec-uti
6
7
8
9 Proposed Budget
I-:-:+-----!Siibco.10 Currently unde$ 11 .............j.t..r.a...d..s.....
$ 1 fO,780 $ 136, 35$ 1 fO,780$
un-
(@
150,000
ec- 'Ola,
{{--, { --@ ------
60,000 $ -$
v,
4L 1,515
I'17 roposea t::>~age
1 ~75$500$ ,,- "
- $ 500 - $ 11,775
-"
22 roposea t::;uagel
"", f tL,U"4 ,,' ,,j"L,btlf
23
24 (" g,
.. 1 n1 ,?7.
25
26
27 ... , n, 28
29
In n~lp
_nR
'n_n7
n, _n' Total
1--,;:-:~+-----!l~;~~~::X~IJ~~~t .. , <1<,< li>cici~;20 ,<~~~;i6i<1~2'~ci~61---+---f-----+-----t---+-----l
32<>,
36 PI"n A 'ot,,1 IUCD~lsc + JCML!I; 5,7~19,RS4 37
38
39 ,au,,, .....' "'L ',a" p - Lauv, "VI ,a, ""v..
40 In n Ie>
n7 n. n' Tnt",
41 Perso...jjjeV.:::.........
42IPr~~~;~cJElGdClet$4()ClC)OO $ 4Clb 000
43~p~nltlllg.
>' 1............................................. 1............ ................................ ..............................................:1>
46
47 Plan B Tota $ 1.2~lo.ooo
48
SH ELL-MCCLU RG-053636
A B C D E FG H I J K LM N0
r49 Subtotal UC HSC + Pia A + Plan $ 6,999,864
50
51 - 52 I.D. v_ "''' "UV"D' r--'''''-'"''''''Y . ",",".. DU '" VV""'" ,,,uuU-"U' '/
.pu, ,uuu
53
...54 "u._
'~' ,uU'
55
56
57 58 59 60 Bud el
Jan- ? Feb-O?
Mar-O?
Apr-O? May-O?
$ 258,85 $ 255,852 $ 129,852 $ 129,852 $ 129,852
Jun-O? 129,852
IT. ?nn7
Jul-O? Auq-O?
ep-O?
o l-O?
Nov-O? Oec-O Costs
129,852 $ 29,852 $12 ,852 $129, 52 $129,8 2 $ 129,852 $ 1,813, 225
61 Fu an $ 126,00 $ 126,000 $ $ $
$ $ $ $ $ $ 252,000
<no : : : : : : : '\ : :62
r; c," '0' : 'L
'\~~:
'\~~:
'L~:~~: '\~~:
'L~:~~: '\~~: I\~~:
,:~~:
h~: : 'L~:n(
'\~~~
'~~7: ~~~
63
Hislol oy $ 300 $
$
$
$
$ $ $ $ $ $ 3000
64
SH ELL-MCCLU RG-053637
A
1 2 Cases (WHO) & Questionnaire 3 4 5 6 7 CC study 8 9 10 11 Disease progression 12 13 14 15 16 Molecular Epi 17 18 19 20 21 Exposure Assessment 22 23
24 25 26 27 Tissue bank 28
BC
AML Lymphoid MDS AA BP
UCHSC GRANT Accumulative Actuals to date 06/30/06 519-? 520-? 379-? 132-? 32-?
Test data set Analytical approach
Study report
unacceptable not started not started
dose response molecular lesions
progmosis % follow up success
25
dose reponse biomarkers
polymorph isms metabolites
Questionnaires Factory visits
6000 50
Sector analysis IPHS review
Database translation and query
shoe making % complete
Supported
yes
D Projected for 07/01106 to
12/31106 87 87 63 22 5
painting, rubber, home remodeling
yes
E Projected for 011112007 to
06/30/2007 87 87 63 22 5
machine maintaince, printing
yes
F Projected for 07/0112007 to 12/3112007
0 87 0 0 0
complete
yes
SH ELL-MCCLU RG-053638
G
Projected totals
1 12/3112007 2? 3? 4? 5? 6? 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
24 25 26 27 28
SH ELL-MCCLU RG-053639
AB
1 2 Expenditures:
3 4 5 6
7 8 9 10 11 12 13 14
15 16 17 18 19 20 21 22 23 24
25 26 27 28
29 30 31 32 33 Total Expenditures: 34 Total Grant Funding:
35 36 Other Costs: 37
38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
Personnel: Total Personnel: Operating Expenses
Total Operating Expenses: Sub Contracts:
Total Sub Contracts: Travel: Equipment: Total Equipment: Indirect Costs: Total Indirect Costs:
Field Expenses
C DE FG
ul"n",1" ul'<A"
UCHSCGRANT
Projected for
Accumulative Actuals UCHSC GRANT Projected for
011112007 to
UCHSC GRANT ENDS
to date 06/30/06
07/01106 to 12/31106
06/30/2007
Projected totals 06/30/2007
Personnel at UCHSC: $ Other: $ $
Expendable Supplies: $ Non-capital Equipment: $
Services $ Maintenance: $ ME feasibility Study $ Contingency: $
$
Fudan University (1) $ IPHSC (2) $
SMCDCP (3) $ EMBSI (5) $
Children's Hospital (Cincinnati) (6) $ Histology (7) $ $
$
Capital Equipment: $ Shippinglimportation
$
Overhead: Other:
$
$ $
$
2,402,457 $ 3,900 $
2,406,357 $
1,353,110 156,787 212,557 51,288 8,160 43,330
1,825,231
$ $ $ $ $ $ $
5,121,580
170,077
153,004
2,515,754
336,834
-
8,297,250
$ $ $ $ $ $ $
9,218 $
1,383,491 1,383,491
$ $ $
1,129,984 $
1,129,984 $ 15,051,530 $ 15,761,880
1,181,486 $
278,515 $
-$
278,515 $
-
400,000
$ $ $ $ $ $ $
850,989
-
402,075
58,800
-
1,311,864
$ $ $ $ $ $ $
500 $
-$ -$ -$ -
176,544 $
-
1500000
131,000 :Ii
278,515
-
278,515 $
-
250,000 $
425,495
-
407,700
61,740
-
894,935
$
-$
-$
137,414 $ $
1070889 $
100,942 $
2,963,387
2,475,231
10,504,049 9,718
1,383,491 1,443,942 18,779,817 18,332,769 1,413,428
&[DATE]
SH ELL-MCCLU RG-053640
HI JK
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
L
M N0
&[DATE]
SH ELL-MCCLU RG-053641
P Q R ST
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 &[DATE]
SH ELL-MCCLU RG-053642
A 61 62 63 64 65 66 67
B
C DE FG
&[DATE]
SH ELL-MCCLU RG-053643
HI JK 61 62 63 64 65 66 67
L
M N0
&[DATE]
SH ELL-MCCLU RG-053644
SHS Oversight Committee Call
Date: Nov. 9, 2006
Attendees:
Trish
ExxonMobil
Brian Doll
ExxonMobil
Steve Bose
ExxonMobil
Michael Bird
ExxonMobil
Howard Feldman
API
Bruce Jarnot
API
Russ White
API
Patsy Clegg
Shell
Stuart Cagan
Shell
Mike Johnston
ConocoPhillips
Jennifer Galvin
ConocoPhillips
Mark Fitzsimmons
Steptoe&Johnson
Zack Wong
Chevron
Don Burnett
BP
Establish quorum and note taker - Patsy
DONE
Review antitrust guidelines - Mark
DONE
Update on Dr. Irons' budget request - Jennifer
o Decision: Budget Package Oust recd. minutes after the call started) would be
forwarded. DONE
o Decision: Bring company decision or strong indication of direction on recd.
budget to Dec. 13 mtg
o Decision: S. Cagan will receive Otto Wong's budget for extending the study until
2007.
Planning for the meeting in December - Zach
o Decision: The OC decided to stay in San Francisco at the St Francis on Union
Square.
o Decision: Trish will organize the location of Wed. night dinner
Update on University of Colorado financial review (cover letter attached) - Russ
o Decision: The OC acknowledged receipt of the Financial Review.
3Q financial report - Russ It has been sent out, all comments should be returned to
Russ.
Update on contract renewals - Russ In progress or waiting for signatures for:
o Herrick and Cherrie (10M) - signatures
o Applied Health Sciences - signature
o Fudan University - in progress
o Steptoe&Johnson - in progress
NOTE: Contracts expire 12/2007 between API and sponsoring companies. The committee reviewed and agreed to continue contracts with API (admin) and Steptoe&Johnson (legal) per prior agreement.
Other business/next call - Patsy o Next Call: Friday, Nov. 17, 2006, Russ to send out confirmatory email/call in numbers.
SH ELL-MCCLU RG-053645