Document evDeBrjR06MQEXRk17RqV5KYe

F. H. Jolwmnaen - General Offices - A280 July 31, 1975 0. L. Bratsch-B3*A 0. J. Lvlnska*-A2SC STATUS REPORT OF EPIDEMIOLOGICAL SURVEY 0. Rouh-A2SA For the pest Sevan davalop a statistical approach toward* further defining tha health sxparlencee of those persons eaployed (past and present) In Dapartgiant 246 - Aroolor of tha Kruaarleh plant. Tha following report covers tha progress we have made In that direction to data. Photocopies of service records of each aaployaa who has passed through the Kruaarleh plant personnel office froa approximately 1930 (the beginning of our records) to tha present nave bean coded and delivered to the Medical Department for review. Relevant epldealologlcal data have been abstracted froa these service records of those persona previously and presently eaployed In Departaent 246. This review yielded tha following lnforaatlon: (1) According to their work histories, a total of 317 parsons wars Identified as having worked In Departaent 246, (2) Approximately 33^ (120) of those on record as having worked In Departaent 246 were fired, resigned or ware otherwise lost to followup, (3) Approxlsately 45J< of those workers (l4l) listed as employed In Departaent 246 actually reaalned In that departaent longer than a total of six nonths throughout their working years at that plant, (4) Only 48 aortalltlee have been Identified froa that Initial population of 317. Omission of those aaployed In Departaent 246 for lead than six aonths, yielded a aortallty popula tion total of 24 persons out of a population of 137 employees having spent significant tlae In that section of the plant. Because of the small number of aortalltlee observed In > Departaent 246, Interpretation of any relationship between cause-and-effeet froa a disease-specific viewpoint can only be HONS 030778 0. Roush July 31, 1975 Page Two Interpreted by direct comparison using a statistical approach, such as a llfetable method of analysis. Recent efforts have yielded access to a magnetic tape containing a llfetable analysis program. Further evaluations are underway to determine whether this program Is accessable and applicable for use In the needed statistical study of the Department 246 population. While efforts thus far Indicate that the program we now have can be of use to us In the future, any attempts to make a full Interpretation of our data at this time would be only conjecture. Before a final epidemiological study can be conducted ln-house, age-speclflc, sex-speclflc and cause-specific death rates must be obtained from a comparison population (l.e., U. 3., Missouri, and/or St. Louis) similarly existing during the years 1950-1974. Information needed to develop these rates has been requested from the Bureau of Vital Statistics In Jefferson City, Missouri and will be forwarded at their earliest convenience. In summary. It should be mentioned that certain groundwork needs to be laid before any sophisticated statistical analysis of popu lations can be conducted ln-house. Such necessary Items as an adequate computer program and Information concerning a typical control population (for comparison of rates) must be obtained, evaluated, "debugged" and otherwise digested before beginning suoh a statistical endeavor. It should be recognised that those outside concerns already proficient in the area of epidemiological analysis have passed through this stage and are capable of pro ceeding directly Into an evaluation of our data. FRJtjea y7. R. Johannsen MONS 030779