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sn 1 Ae226-177) CANCER PREVALENCE IN SUBJECTS EXPOSED TO PERFLUOROOCTANONC ACID (PFOA) James Dahlgren \(p', Ayman B Ibrahim Mpa. Raphael Warshay,?, Harprest Taha, Mey? 1 UCLA School of Medicine, 5, Comprehensive Heap, Sereening 3 Dahigten Medical Group Services, Plezse address correspondence ro; James Dahlgren, vi 2811 Wilshire Biya, Santa Monica, CA 90403 Voice: 310-249.5525 ext, 206 FAX: 310.449.5576 Sehleren@envinmtonicology com ; SKeessyiowno:rdPse:rfplruoonr.ing7t0e5d,spuebasst,ancgge,sFH Eee, a ronmena expo, Moorochermcsis : LE 1306 Perfluoroociznonic Acid (PFOA) is a man-made perfluorooctaned chemical, which is also seferved 10.25 CS. PFOA is a key ingredient agent in the productionof Teflon 2nd other cfhlruoonriaccheexmpiocsss!repr1l0uPctFsOA2nodftishebiorpeesrisdiesnitesntnenard2 bpiloaancteuusmiunlgatPeFs.OTAhearned hoatshebrefelnuodroicnuatmeednted contaminans. pOouprulaaitaiosns(re0sidceonmtps)arteo tchaantcoefrthdiesribndeutsitorny scanndccearnrceegrispredvaalteancferoramceasnionc2euPpFiOoAn-kelxpeoxspeodsed rPeospiudleanttisolniavinndg fnienaalr2y PtoFtOheAguesnienrgalmapnoupfualcattiuornin(gSEplEaRn)t.oWpeerapteerdfboyrmDeudpo2rqsu,esCtainocnenarirreegiosntr$y99 aagiaeinsftoDmupthoentPFanOdAwDauspnoonttpwroervkioeursslwyamsadmeadaevaaivlaaibleabtloe tthherosucigehntdiifsiccocvoemrmyuinnipteyndfionrgrelviigeaw.tion The SEER data was used for comparison to the general population. +1 The overall cancer prevalence rae is higher in the PFOA-exposed population when compared to the general population. data, resident deta and Comparison of SEER is shown cancer prevalence in Table 1 rates for the industry cancer regisiry HOauvrefeilnedviantgesdicnadnicaetreptrheavtatlheencPeF(OTAabelxep1o)s.ePdrorsetsaitdeenctainalcepropinultahteiorensaidnedntPsFOwAa-sepxrpopoosretdiownoartekleyrs elevated among young the resident population age males. compared Cervix and uterine to the U.S. general cancer rates population. in women were also higher in tThheefdiinsdtirnigbsuotfioenloefvaciaendceprrsevianltehnecerersaitdeesntosfatnydpiwcoarlkecransciesrdsisffuecrhenats tNhoann-eHxopdegckteidn,'sQ,fLneoutkeemariea, and Multiple Myeloms. (Twhoirskdeartaansdtgrgeessitdsentthsa)t aenxdpomsauyrebteo aPnFiOmApTorntaaynatlrtiesrk cfaancctoerr dfiosrtarnibeuxtcioenssiosfecxapnocseerd cpaosepsu,lations : LE 1807 es i Ss i SH [He C