Document em7Q11j7Dman3Xn0d4nX0qdYm

7,0 mo up omjm* *ud, rnou Klehard Hndirra SUBJECT 1ATtotfrd/ -i AT Maw Ira 1-1-5 date Juno 26, 1970 COPY TO m (2) InniTnsrt la a mu of a Isltar trm Hr. V. t. hoCoralck, of the B. f. Ooodrlob Canpoay* Inolndlwg ths procedure that Ooodrloh moot for oold lnoalt tooting ** pro-pi Trant toot for parsons who nay bo ooelgnort to <-g rosetors in polyvinyl ohlorldo ploato. If poo agroo that this in a soltable tMt, X suggest that poo My **& P it on to Or. Sqplllanto. Also onoleood with *. MoCorw&ok*o lottor In an abstract of a paper that woo presented at tho lhath International Cmoot Congress In Braton, TOzaa recently. I beliere that this should bo of groat ooneern to ao and will oontlano to try to find additional laforastlon on tho subject. KHiaph Inol. Richard Bondsraon WHT 8 0801THI% CObYT \W YOU MUfT fttTAIN ft, fPgCirY A Of FIMIT AfTlMTlOM O' OLI 2359 TMf O V 1 tttofctAJh CONCLUSIONS X* Laboratory animals vara exposed repeatedly to 100* 50 and 5 ppa of vlnylldene Ohioride vapor aavan hours a Car* flva days a vaak for a period of up to six and ona half months. 2. Toxic affabts vara aaan at all levels. However, at tha 5 ppa concentration# thaaa affaota vara oonsldarad minimal and probably of no practical significance. 3* Homans exposed to 50 ppa of this aubatanea vara unable to detect, the material. Tha coming properties of vinylidene chloride therefore are not sufficient to prevent exposure # likely to be harmful when repeated dally for prolonged periods* t. An industrial hygiene standard of less than 25 ppa is sug gested* In vlov of tha human experience vlthln Tha Dov chemical Con?any, vo believe there vlll be little chance of injury occur ring if exposures do not exceed 50 ppm and if tha average con centration (tlme-velghtod) to vhloh vorkmon are exposed is OLI 2360