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000365
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y PJ> CStMUSMEDUKU E. 1. du Pont de Nemours Si Company
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Spruance Plant
P.O. B ox 27001 Richmond. Virginia 23201
TEXTILE FIBERS DEPARTMENT
fi-R # & 6 -3 y-3 l
Beibruary 25, 1990
PKBSOH&L & CONFIBEKTIAL
TOi 6. L. WATTS
FROM: E. R. PURCHASE
P FC-143 FLUOBOSURFACTANT (Ref. s L e tte r, A. A. Wright to M. R. Werden, same subject, 10/29/79)
The reference le tte r reviews information on PC-143, a 3MCompany product, used a t Parkersburg in Teflon dispersion which in tu rn is vised in Teflon opera tions a t SpruSuce. Blood te sts on employees who work w ith PC-143 showed up to 70 ppm of organic flu o rin e in 3M employees and up to 22 ppa in Parkersburg em ployees compared to a general background level of le ss than 1 ppm. No adverse health, effect has been detected in any o f the exposed people. Tests a t Haskell Laboratory revealed th a t PC-143 readily penetrates th e skin of animals and causes liv e r damage and in heavy doses may cause death. In view of th is inform ation, a decision was made to analyse blood samples from a sm all group of Spruance employees with p o te n tia l PC-143 exposure In Spinning and Finishing and a control group.
The analyses o f blood samples were carried out a t Jackson Laboratory by the same group th a t analyzed samples from Parkersburg. The re su lts are shown below
Employee
Age
37 58 25 28
37 32 31 24 35
(1) N on-volatile (2) By difference
Area
Spin. Spin. Spin. Spin. Pin. Fin. Control Control Control
T otal (1)
0.34 0.41 0.18 0.23 0.35 0.18 0,21 0.18 0.18
Fluorine, nun
InoiBMlinlc Organic
0.21 0.13 0.12 0.29 0.11 0.07 0.15 0.08 0.15 0.20 0.18 0.00 0.20 0.01 0.14 0.04 0.15 0.03
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B ET TER T H IN G S F O R B ET TER LIVING , . - TH R O U G H CW EA U STW
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000366
G. L. WATTS
-2- February 25, 1980
These re s u lts Indicate th a t there is no sig n ific a n t exposure to FC-143. th is view is supported by personnel from Haskell Laboratory Jackson Laboratory and the Parkersburg plant who consider th at blood lev els of organic fluorine below 1 ppm are not significant Therefore, we plan no fu rth er an alysis of blood samples from Spruance employees .
To ensure continued protection o f personnel against exposure to EC-143, operating procedures w ill continue to be based on no skin contact w ith Teflon dispersion. Ko sp ecial precautions are required fo r yam handling. In routine periodic au d its o f operating area conditions and p ra c tice s, sp e c ia l atten tio n w ill be given to those factors which p ro tect employees against exposure to EC-143.
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RL001723
KL001723 000367