Document e5aMnmGEQEQvK4OZRpakg9ZXm
IMPERIAL CHEMICAL INDUSTRIE# LIMITED
rustics DIVISION
LIVER Mglo*feo C* - (lkvlH Cc| 4 Ttbriury 1941)
r*|4 2i
10 12 13
15
COUNTRY AND
REFtitHCE
NO
NAME OK INITIALS
DATE OF URT1I
COMPANY
FACTORY
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
ACE AT DIAGNOSIS
TEARS OF EXPOSURE TO
DIACKJ3IS
YEARS Of EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
UVEL
OCCUPATION
OTHER CAREER HICKLIGHT3
OTHER CCMHP.HT2
YUC0SLAY1A 01
02 03
1 1 1 \
1 J ! 1 1 1 t 1 J l I 1 1
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Ipipir (Ena rtoAltli '*' IParipaetlvi 1Vo1 17, Ipp 149-m 11976
I I |`la hie lai [of 3 Oct V. tbr Solrtaa (NIOSK cHarti |thi atatue
(Ca 02 to
Iprtduttloi (employ*'**
|Dr (ptitii itleo notll:
| oav Can |ileo a VC
(production |vorRr
04 1 1.06.30
IS. 11.34 03.09.74
AS
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(Rosa Ramin
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I
TABLE 1
Page 24
Incidence of ASL Cases Per Annum
1955 6 7 8 9
1960 1 2 3 4 5 6 7 8 9
1970 1 2 3 4 5 6 7 8 9
1980
Total
By date of death
1 '0
\
0 0 0 1 1
0 1 0 1 1 5 3
2
3 5 7 6 n n 9 10 4
JPT $$
N.B.
1 Doea not include Itallan'01 but does include German 03.
2 Does not include Japanese suspect cases, Since post mortem examinations are rare events In Japan, confirmation of ASL Is a problem as Indeed la Its discovery,
3 .The 1977 total Includes US case 24 whictj Is a Cholanglosarcoma,
see
-1 1 0 6
Page 29
TABLE 6 ASL CASE NUMBERS BY ^EEAR OF DEATH AND GEOGRAPHICAL LOCATIONS (EXCLUDING ITOO
l'
l l
( \ | 1955
16 17
1 8 l9 I 1960
(1
12 J- l 3
I. 4 |5
t6 l ' '7
|Viola
18 19 I 1970
|Kaltoni
|Goodrich |
1.1 !2 13
l 4*
t 5(. 6
r 7* 18
t9 | 1980
1 l | Total
_!
WESTERN EUROPE
FI * G1 Swl G2 Ni;Sw2,UKl,It2 G3** G4,G5,UK3 F2,F3,G6>G7,G8,It3 Bl,F4,F5,F6,F7,Sw3 F8,S9,G10,CU,G12,Sv4. F10,F11,G9,G13,G15 016,017 F12,F13,OK4,UK5 UK6 r UK7
43
* Cholangiosarcotna. ** Aerosol Can Filler
FJST80061400,1-WPX7-2 .
1 |' ' NORTH AMERICA l l [ Cl 1 | C2 1.
| US8 | C3 l l US5
I
1 t REST OF WORLD 1 {
1 l 1 1 | 1
1 **- l
i Cz2
I C4fC5.USA.USI.USIO | US12,US16 1 US11 | C6,U2 I C7 l C8,US1,US3,US23 | C9,US13 1 US6,US9 ,0518,11526 t US19,0S2Q,US22r { 010,0521,0524* | US27,0528
| US17, US29
! 1
1 l I l Y1.Y2 l Czl [ Japl | Jap2,Y3
1 | 'Y4[
i I 1
1 36
" 18
see
1-1107
Page 30
TABLE 7
ASL CASE NUMBERS BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL LOCATION (EXCLUDING rroi)
lt
1 l WESTERN EUROPE
lI
1
I 1939 1
l 40 1 1 i Frll
*
2
13 l 4 UK1
I 5 Sw2 i 6 Frl,Fr3,Sw4 '
1
7 Sv3
.
1 8 Fr9
l 9 Frl2,Fr4
l 50 Fr7,Nl
1 1 Swl,UK5
1
1 _j
2 G3** 3 G15,Ic3 4 G7,G8,UK4
1 5 G11.G16 1 . 6 7R10,G1
1 T Fr8,G4,Ic2,G2 { 8 Fr6,B1
1 9 Fr2 . l 60 G5,G13 1 1 1 G9,G10,G12,G17 1 2 I* G6 ,tnc6 1 3 Frl3, UK7 l 41
5 Fr5`
1 6 UK3
( 71
*
1 8l
9
Viola 1 70 1
1 111 { | 2|
Maltoni 1
31
1{
l Tocalt 43
1
* Cholangiosarcoma ** Aerosol Can Filler
P JST80061400,2 WPX7-2
NORTH AMERICA
1 { US24* 1 { C3,US27 1 US13, US29 1 C2,US19 l Cl,C5 ,US5,US7,US28 1 C4,US3,US9 ( C7^C9,US8,US1X,US21 l C6,US22,US26 | US1 I US12 l US16 l US10 . | US4 |* CIO J US 18 1 US2fUSl7,US20
{ US23 I 1 1 C8 | US6-
1
l
1 1 [ (
1 36
l l REST- OF WORLD 1
1 i 1
1 1 1 l
(.-
1 -Y2" ! Cz2 1 l Japl.Yl 1 Y3 1 1 l Czl I Jap2,,Y4
1 1
1 1 1 1
1 |
1 18
l
l | | 1
1 l l
1 1 l
1 1
1 1
i
1 1 1 1 .( 1 1 1
I 1 l l ( l 1 l
see
1-1108
WESTERN EUROPE PVC PRODUCERS START-UP DATES vs ASL CASES (OMITTING C03)
-
|START-UP ( COUNTRY NAME | COMPANY NAME
YEAR |
(
1940 1United Kingdom (ICI
1941 1 France
(Rtrone-Poulenc
1944 (West Germany (BASF
| LOCATION
l iRillhouse (St Fons (Ludvigshafen
( ASL CASE
( NUMBER (01,04 (03,09,10,11
( YEAR OF
( Lst Exposure (44.54(46.48,56,41 .
(West Germany 1Wacker
1945 {Sweden
(Keaanord
|Burghausen
(04,07,11,15
(Sundsvall(Stockvik)(01 ,02,03,04
(57.54.55.53 !51.45 .47.46
|Switzerland 1946 (France
(Lonza
(Lalden (Visp)
(Rhone--Poulenc (Rouslllon
1 (01
l (46
1947 \Italy
(Montedison (Porto Karghera
(02
157
1948 (United Kingdom (BP Chera
(Barry
(03,05,06,07
(66,51,62,63
(West Germany (Huls
| Marl
(09,10
(61,61
1949- (Belgium
1Solvic
(Jemeppe
(01
' (58
1950 |France
(Puk
(Brignoud'
(02,04,05,06,12 (59,49,65,58.49
(France
I Rhone--P oul enc (St Auban
(07
(50
|Holland (Norway
(Shell (Norsk
(Pernis (Heroya
.1 (01
( 150
1951 (Italy
(Montedison . (Brindisi
1952 1953
(Italy 1 Austria 1 France (Italy (Spain
(Montedison (Halvic (Solvic (Solvic |Rlo Rodano
|.Terni (Hallein (Tavaux (Ferrara |Hernani
1
(08,13 103 (
i
(57,63 [53 |
(United Kingdom!BIP (West Germany (Hoechst
(Aycliffe (Gendorf
(-
(
1954- (West Germany {Dynamit
(Troisdorf
(01,02,08,12,16, (56,-57,54,61,55.
`l 1
1
(17 161
1955 (Spain
(Monsanto IberialMonzon
1956 (Spain
(Caiqsa
(Sablnanigo
l |Hispavic 1958 (West Germany |Solvay
(Torrelavega (Rheinberg
1960 1 Italy 1962 (.Portugal
lS C Ravenna (Cires
(Ravenna (Oporto
|,
[
(West Germany (Lonza
|Waldshut
(06,13
(62,60
1965 [France
1 Rhone--Poulenc j Montlucon
t
l
1Italy
IPozzi
(Ferrandina
(West Germany iWacker [ , 1966 ( West Germany ( Hoechst
(Cologne (KnapsackCFrankfurt)J05* '
(60
1967 (France
(ATO Chimie
(Balan
I Spain
(Rio Rodano
(Miranda de Ebro
(Greece
(Esso Pappas
(Dlavata Salonika
1968 (Belgium
(Badiphil
I Antwerp
1969 (United Kingdom!Vinatex
(Staveley
I Italy 1970 1 Italy
{Rumlanca (SIR
(Cagliari Sardina (Porto Torres Sar-
1 United Kingdom(lCI
(Runcorn
1971 (Italy 1 Spain
(S C Ravenna {Hispavic
lRavenna |Martorell
1
(
(Sweden
(Kemanord
(Stenungsund
(United Kingd'o m( BP Chem
(Baglau Bay
1972 lFinland
iPekema
(Svartback
l
1
(Holland
(DSM
[Beek Limburg
I
l
1976 (.France
(Soc Art D`vinyl|Mazingarbe
l
l
1977 [Spain
|Monsanto Iberia[Tarragona
* Laboratory worker in Research Department
PJST80061400,3-UPX7
SCC
1-1109
USA PVC PRODUCERS - START-UP DATES vs ASL CASES
(START-UE 1 COMPANY NAME
LOCATION
{ ASL CASE i YEAR OF
YEAR
I- NUMBER
| 1st EXPOSURE
1939? [*UCC
S Charleston
107,13,19,21,24,144, 42, 43, 46,
1940? | *BFG
Louisville
|27, 28, 29
|39, 41, 44. 42
101,02,03,04,05, (4 8,55,45 ,52,44,
l 106,09,16,17,22,162,45,50,55,47,
1946? i*ucc
Texas City
|26
(47
1947 | Goodyear
Niagara Falls
[08,10,11,20
146,51,46.55
1948 f Firestone
Pottstown
(12
|49
I Uniroyal 1950 1 Monsanto -
Painesville Springfield
(
(
1952 I Dow | BFG
Midland Avon Lake
(. {18
1 154-
1953 I Diamond 1954 1 General Tire
Deer Park Ashtabula
1
(
1956 [ Air Products
Pensacola
( Atlantic Refining Brooklyn
( Borden
Leominster
| Conoco
Rebronville
| BFG
Niagara
| Great American
Flitchburg
123
|58
1 Plastics
1 Hooker { Pantasote
Hicksville Passaic
t
1
1957 | Atlantic Tubing
Cranston
| Tenneco
Flemington NJ
1958 | Keysor Century 1960 [ BFG
Saugus, Cal Watson, Cal
i
|
l Air Products
Calvert City
(
|
( Borden
Illiopolis
1962 1 Tenneco
Flendngton NJ
1963 [ Conoco
Aberdeen, Miss
1 Stauffer
Long Beach, Cal
1965 | Conoco
Aseonet, Mass
1 Ethyl
Baton Rouge
1966 ( Diamond
Delaware City
jGeneral Tlre/Pantas Me Pleasant W Va
( BFG | Stauffer
Henry, 111 Delaware City
r
|'
1967 i Allied
Painesville, 0
| Hooker
Burlington NJ
1968 ( Firestone
Perryvtlle
1969 | BFG
Pedrickton NJ
1
.
| Goodyear
Plaquemine.
1 Olin
Assonet,'Mass
1971 | Conoco
Oklahoma City
1972 1 Nat Starch 1973 1 Borden
' Meredosia,- 111 Springfield
1 1
"1 r
1974
| Robintech | Atlantic Tubing ( Shintech
Painesville, 0 Cranston RI Freeport, Tex
1
t
1
l
1975 { Certain-teed
Lake Charles
l
i
I Georgia Pacific
Plaquemine, La
[ Tenneco
1 Pasadena, Tex
[
1
* My databank has no information on UCC before 1946 or BFG before 1950.
NB Some' of the plants in this list were closed down some have changed ownership over the years.
p r^TftnnAiiOO.4-WPX7/2
1 10
Page 33
TABLE 10
* CANADIAN PVC'PRODUCERS - START-UP DATES vs ASL CASES
|START-UP 1 l TEAR |
COMPANY NAME
l 1943 | Goodrich
(1941?) 1
1951
1
1 l Monsanto*
1957
1 l ( Goodrich
1966
t
l 1 Esso
1
* Terminated 1975
| LOCATION
i Shawinigan l
| La-Salle
1 l Welland 1 1 ( Sarnia 1
| ASL CASE | NUMBER
(01.02,03,04,05 (06,07,08,09,10 1 t
1
1 t 1 (
( YEAR OF 1 1st EXPOSURE . ( (44,43,41,45,44, 147,46,61,46,53 1
1 \ [ l ( t
see
1-1111
Page 34
TABLE 11 EASTERN BLOC-PVC FACTORIES - START-UP DATES vs ASL CASES
| START-UP | COUNTRY NAME [ COMPANY NAME
YEAR J_________=__ \
194 1 (Russia
(State Comps
X950 (Yugoslavia
[Jugo Vinil
1951 |Czechoslovakia IS cate Comps 1955 (Ease Germany (State-Comps
1 1956 t Rumania
1 |State Comps
1957 (Poland (Rumania
(State Comps (State Comps
1958 1959 1961 1963 1965 1967
1' (Rumania (Rung ary (Rumania (Yugoslavia (Bulgaria (Poland
\ (State Comps (State Comps (State Comps (Ohis (State Comps (State Comps
1969 (Russia
(State Comps
1970 1972
(Rumania (Russia (Yugoslavia
(State Comps (State Comps (Vinilplastika
1975 1976
(Czechoslovakia (State- Comos
(Russia
(State Comps
(Yugoslavia
(Hip
1977 (Rumania'
(State Comps.
( LOGATION
t
(Vladimir ec al (Split INovaky (Bitterfeldt |Schkopau |Icechim (OsMsicim (Dwory) |Tirnaveni (Turda (Risnov (Berente Borsod |Borzesti (Skople 1 Varna (Tamow (Dlerlinsk (Rimnicu Vilcea 1 Volgograd (Zadar (Neratovice (Kalush Area (Pancevo (Rimnicu Vilcea
PJST80061400,6'-WPX7
( ASL CASE ( NUMBER
I 01,02,03,04 (01,02 { ( 1 l [ I
l
I 1 1 [ 1 ( 1
[
1
l YEAR OF I 1st Exposure 1 (53,50,54.48 (57,51 ( \ 1 t J*
1
( 1 1 {
I
SCC
1-1112
TABLE 12
Page 35
JAPANESE PVC PRODUCERS - START-UP DATES vs ASL CASES
lSTART-UP T COMPANY NAME | TEAR | 1950 | Chisso Corp
[ Kanegafuchl Kag { Tekkosha 1 1951 I Mitsui Toatsu | 1952 |* Mitsubishi Mon | Sumitomo Kag | 1951 | Denki Kagaku 1 Nippon Zeon 1 Toa Gosel | 1955 ( Ryo-Nichi t 1956 | Nippon Zeotr | Nlsshin Kagaku 1 1957 ( Kureha. Kasei ( Shinetsu Kag I 1960 ( Denki Kagaku | Kanegafuchl Kag l 1964 I Chisso Corp I 1966 | Tokuyama Seksul l 1967 | San Arrow Kagak l Sumitomo Kag I 1968 1 Ryo--Nichi 1 Shinetsu Kag I 1970 ( Chisso Corp ( Denkl Kagaku | Kanegafuchl Kag l Kawasaki Yuki
fr Mitsui Toatsu | Nissan Kagaku | Shinetsu Kag l 1971 | Tekkosha I 1973 ( Asahl Glass | 1974 | Toyo Soda i'
I 1975
Central Kagaku
| Tovo Soda
I 1977 l Unknown
l LOCATION
1 | Minamata { Osaka | Sakata I Nagoya | Yokkaichi | Klkumoto | Shlbukawa { Kambara ( Tokushima t Uozu { Takoaka * 1 Takeo l Nishlki 1 Naoetsu t Ohmi | Takasago ( Chiba | Tokuyama | Tokuyama [ Chiba ( Mizushima | Tokuyama | Mizushima i Goi (Chiba) t Kashima [ Kawasaki [ Sakai [ Chiba { Kashima ( Yokkaichi { Rayatsuki | Sakata 1 Yokkaishi ( Kawasaki
i Yokkaichi 1 Kashima
P JST800,61400,7-WPX7/2
OJ
O O
1 ASL CASE l NUMBER
1 1
1 I
l ! 1
i
l
\ {. 1
1 1
\ YEAR OF
1
1 1st EXPOSURE
1
1
I 53, 58 l 1 l ! 1 l
\
1
1 I
1 11 l1 1
II 1
11 \
( 1
i . -
see
1-1113
TABLE 5
Page 28
Annual Incidence of ASL Cases (Date of Death) by Geographical Area
1955
7 1961
2
A 6
7 8 9 1970
1
2
3 A
5 6
7 8 9
1980
Western Europe
1
l
1 1
k
1 3 6 6 6 7 A 2 A3*
North Araerlca
1 1
1 l 1
5 2 '1 2 1 4 2 4 3 3 2
X3 . 36 37
| 1 [
{
( | | (
1 1 i
1 1
1 1
(
1 1
1 1
t
I
Rest of World
1
2 1 1
2 1 8
1 | Annual Total
1 i1
(1 (1 (1 |1
11 f1
I5
13
12
13
|5 |7
16
l 11
1 11
<9
1 10
14
J_____________ xx.
1 & se
`j
* Includes G03 aerosol can filler buc oiaitfi It 01 bag extruder
H*
see -1 1 1 4