Document dnj23XbxvjjnvBwRpdKkdZEN9

Shanghai Benzene Health Study Questions & Responses 1. What are the ethical challenges? The consortium sponsoring this study recognized prior to committing to the project that doing an epidemiology study in China had ethical issues. An independent Ethics Review Panel was established. The members are Dr. Baruch Brody, chair, Baylor College of Medicine (US) and Dr. Xu Zong-Liang, Fudan University (China). This panel reviewed the study protocols, consent forms, questionnaires, and compensation using the UN WHO International Guidelines for Ethical review of Epidemiological Studies. Below is a list of the Scientific Review Panel and the Ethics Review Panel membership. Scientific Review Panel Area of Expertise I Name General Toxicology and Biochemistry Jerry M. Rice, PhD (Chair) for Research on Cancer Dr. Helmut Greim Epidemiology Dr. Nancy Mueller (Vice Chair) Dr. Harvey Checkoway Statistics Dr. Howard Rockette Pittsburgh Industrial Hygiene Dr. John Cherrie Dr. Robert F. Herrick Hematology Dr. Richard Larson Dr. Mark Minden Genetic Toxicology Dr. Li Guilan Richard Albertini, PhD I Affiliation I Chief, IARC Monographs Programme; International A~ ency I Technical University of Munich I Professor of Epidemiology Harvard School of Public H~alth I Professor of Epidemiology University Of Washington I Professor and Chair, Dept. of Biostatistics University ( f I Institute of Occupational Medicine Aberdeen Universit I Senior Lecturer Harvard School of Public Health I University of Chicago, School of Medicine I University of Toronto I Chinese Academy of Preventive Medicine I University of Vermont, College of Medicine Ethics Review Panel Name Affiliation Dr. Baruch Brody (Chair) Baylor College of Medicine Dr. Xu Zong-Liang Professor and Dean, Faculty of Humanities and Social SCiences, Fudan University, Shanghai, Chma 2. When was the country chair in China aware of the study? Shell recognized an opportunity to participate in the sponsorship of the study in 2000. Shell Chemicals CEC approved the project and it was kicked off 3Q01. The country chair in China was aware of the project in 2Q02. A process to assure that global chemical issues are notified to the appropriate country chair or MACP will be the responsibility of External Affairs. SH ELL-MCCLU RG-06S7S6 Scientific Review Panel Area of Expertise I Name General Toxicology and Biochemistry Jerry M. Rice, PhD (Chair) Dr. Helmut Greim Epidemiology Dr. Nancy Mueller (Vice Chair) Dr. Harvey Checkoway Statistics Dr. Howard Rockette Industrial Hygiene Dr. John Cherrie Dr. Robert F. Herrick Hematology Dr. Richard Larson Dr. Mark Minden Genetic Toxicology Dr. Li Guilan Richard Albertini, PhD Ethics Review Panel Name Dr. Baruch Brody (Chair) Dr. Xu Zong-Liang Dr. Juhanna Idanpaan-Heikkila Affiliation Chief, IARC Monographs Programme; International Agency for Research on Cancer Technical University of Munich Professor of Epidemiology Harvard School of Public Health Professor of Epidemiology University Of Washington Professor and Chair, Dept. of Biostatistics University Of Pittsburgh Institute of Occupational Medicine Aberdeen University Senior Lecturer Harvard School of Public Health University of Chicago, School of Medicine University of Toronto Chinese Academy of Preventive Medicine University of Vermont, College of Medicine Affiliation Baylor College of medicine Professor and Dean, Faculty of Humanities and Social Sciences, Fudan University, Shanghai, China World Health Organization in Geneva. SH ELL-MCCLU RG-06S7S7