Document dakbr3qyrNg7XYpMReKKed446

c data, presented la ttblv l, la bated upon completed observations and .... ,,iO * therefore differs slightly fron a preliminary roportl2)." Introduction of flno quarts Into Ttriout organa of tha guinea pig, rabbit, rat, aouao, eat, dog, ehlekan and even tadpola eventually vill produoe ailleotle no dules but at a dlffuront rate of development* Similar introduction of v. asbestos hat ra suited in a fibroua reaction In the lung and, to a loster extent, in the peritoneum but not In other organs of the guinoa pig, rabbit, oat and white rat. In our experience the lunge or the dog and white aouao failed to raapond with flbroals although Sohuotor(3) hao roported auch ohangoa In a dog that lived in an asbestos fabricating plant. This variation In apeeloa and In organ auiooptibllit/ ia yet to be accounted for(*)| It-le preauaed that in-tha-auaoeptlblo animals tho grtator reaction of tho lung to aabectoe, far exceeding the a reaction of other organ tleeuoa, la due principally to tho greater mobility of the lung* Pocullar Characteristics of Asbestos. Experience hae demonstrated that moot of tlie non-fibrous particulate dust inhaled into tho lungs of man and animal to 10 microns or leas in maximum dimension. Largor parti cles apparently do not gain aooeaa to tho lungs because of two roesonar first, large particles ssttle la air so rapidly that few remain suspended 1. Schuster, li.ll.i Pulmonary Aebeatoaia in a Uog. J. Path. /Tbaot. Sis .Part 2, 751, 1931. 4. Vorwald, A.J.t Varlatlono in Individual Susceptibility to Industrial ' Dusts Inhaled into tho Lungs. An. ttsv. Tubtro. 62i IB, 13, 1950, --6-- i