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I Speci Materials Su PeounlerMY 55148-1000 aS February 20, 2008 Via Hand Delivery Docket AR-226 EPA East Building, Room 6428 1201 Constitution Ave. N.W. Washington, DC 20460 Phone: 202-564-8930 Attention: OPPT Docket No. AR-226 (Toni Krasnic - Room 4410L) Re: Information on Perfluorooctane Sulfonate, Perfluorooctanoic Acid, and Related Compounds Dear Mr. Krasnic: This continues 3M's voluntary submissionsofdata on perfluarooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), and related compounds. We are enclosing a CD which contains PDF copiesofthe following: BM. Elcombe, "4-Week Study to Investigate Perfluorooctane Sulfonate (PFOS)-Induced Hepatomegaly in Male Sprague Dawley Rats," CXR Biosciences, February 8, 2008. + Sump, et al. "An Oral (Gavage) Developmental Neurotoxicity and Thyroid Function StudyofMTDID 208 [PFOS] in Rats," WIL Research Laboratories, January 10, 2008. Krueger, et.al, "POS: A Survival and Growth Sediment Toxicity Test with Chironomus tentans using Spiked Sediment, Final Report," Wildlife Intemational Ltd., November 27, 2007, along with robust summaryofthe study. Lundin, Jessica and Bruce H. Alexander. "Mortalityof Employeesofan Ammonium Perfluorooctanoate Production Facility," Division of Environmental Health Sciences, University of Minnesota, August 22, 2007. February 20,2008 Page 202 In addition, 3M would like to note for the record that its May 23, 2000 submission incorrectly identified the test substance in the study at AR226-0379 as N-ethylperfluorooctane sulfonamidocthanol. The test substance is correctly identified as N-methylperiluorooctane Sulfonamidoethanol in the submission of the same study at AR226-1030a 075, Please feel free to contact me with any questions. Very truly yours, _ eB Jti ie7 fo / Michael A. Santoro Director of Environmental Health 3SaMfetCyenatenrd,RBeugiulldaitnogry23A6f-fa1iBr-s10 St. Paul, MN 55144 651-733-6374 (phone) 6E-5m1a-i7l3:3-m1a9s5a8n(tfoaxr)o@mmm.com Enclosures ce: Dr. Jennifer Seed (w/o attachments) Mr. Charles Auer (w/o attachments) Dr. Oscar Hemandez (w/o attachments)