Document dY77dXoo53z1BOyKRyNzo6206

Monsanto/,. 7 ,r~ t'\ oA J . Colemaii Weber, G e n e r a l Offices, BjjSc September 27, 1972* . CHL0R0PHE1I0LS TOXIC BY-PRODUCTS T O : E. E.. Hendrikse, B 3 S C ce. L, G. Schai*pf, N I A D. P. Romn, NIA P. L. Wright, A 2 S A H. J. Horner, Kfummrich, 17I0 S. H. Vogel, Krummrich, 1740 D. K. Lynch, Krummrich, 1740 T-\0 Attached Is Jim Mieure's memo of September 26, 197^* on the analysis for 2, 3* 1> 8 Tetracblorodiben?o-p-Dioxin (TCDD) of seven samples from the Chlorophenol process. The results Indicate a potential problem with the Still Residue but not with, the refined products or the fraction feed for Penta (Dept, 236). The suggestion was made to run a biological test on the Still Residue. It may also be beneficial to run biological tests .on the other samples. I will discuss this with Paul Wright in Medical, Dan Roman and Lou Scharpf, and decide what' should be the next step. I will also touch base with Bill' Papageorge since he is concerned .about the safety of Penta. Until we have more data, I recommend that we do not take any action on WGK's proposed Investigation submitted in August. r* JCW:slv Enclosures J. Coleman Weber i - 1C n cv. \ 7J cp. C010 96 o? / o CHLOROPKENOLS DEPT. 2^.7 - WOK SAMPLE IDENTIFICATION JIM MIEURE'S MEMO 9/26/74 1. Still Residue from Dept. 237 Fractions for feed to Dept. 236 (Penta) 3. Chlorinated Batch (#G32) Department 237 sampled right after completion of chlorination step. , . / Refined Para Chlorophenol Lot "f Ko\ --K--D---5--0--8N3} (7/11/74) Refined Para Chlorophenol Lot No. KC 5118 (12/4/73) 2,4 - Dlchlorophenol Lot N o Q c D 1003^.(3/15/74) 1 J 2,4 - Dlchlorophenol Lot No. KC 81011 (Tank Car GATX 60233-8/24/73) t . --1' V * ,JIUo.l,s LJ / SANTOPHEN PRE-1979 Description Santophen Samples KE-03-15 KE-08-41 KI-02-;44 KI-04-79 KI-04-83 KI-04-84 KI-05-94 KI-05-104 KI-06-109 KI-06-124 KI-06.-124 KI-07-155 KI-07-159 6 Production Lots KK-08-107 KK-08-117 KK-09-127 KK-09-139 KK-10-151 KK-11-169 KK-11-182 KK--12--191 KK-12-201 Date TCDD Level-ppb Source Document 4/74 3/75 8/75 2/8/77 4/10/77 4/15/77 4/16/77 5/1/77 5/27/77 6/4/77 6/20/77 6/20/77 7/22/77 7/25/77 2/77 to 7/77 8/78 8/78 9/78 9/78 10/78 11/78 11/78 12/78 12/78 ND Deft1s 945 ND Plff's 1111 ND Plff1s 1111 ND Deft's 878 ND Deft1s 878 ND Deft's 878 ND Deft* s 878 ND Deft's 878 ND Deft's 878 Deft's 878 ND Deft's 878 48 '*W AKfACffiS - Plff's 1135 and 1138 ND Deft's 878 ND Deft's 878 ND Plff's 1122 14.2(0.5)*-) Plff's 1285? Deft1s 877 26.1 (ND)* Plff's 1285? Deft's 877 10.5 (0.5)* Plff's 1285; Deft's 877 38.6 (ND)* Plff's 1285? Deft*s -877 <8o 33.2 (1.4)* Plff's 1285? Deft's 877 124.3 (ND)* ras 18.6 (1.2)* 6.0 (2.2)* J)10.3 (2.9)* Plff's Plff's Plff's Plff*s 1285; 1285? 1285? 1285? Deft's Deft's Deft's Deft's 877 877 877 877 ( )* ND Number of total ppb of TCDD co-eluting with 2,3,7,8 TCDD standard. None detected at current level of detection or at level of interference. SANTOPHEN 1979 Description Date KL-01-06 - rauS-fs 1/79 KL-01-06 K L-01-14 1/79 1/30/79 KL-02-25 2/79 kl-oS-43--u/ijout'cawsHc 3/2/79 KL-03-43 -'T ulli r r t& c d 3/2/79 KL-03-67 3/30/79 , KL-04-69 4/79 I KL-04-74 4/13/79 KL-04-02 nab nrrsddh -mb-1391 tn VMB-740 >' 4/29/79 5/7/79 5/7/79 h crh jp rp ^ C^ ' M B" 741B ^ 5/7/79 KL-05-90 5/16/79 KL-05-103 5/79 KL-05-104 5/31/79 KL-06-110 6/79 KL-06-113 6/79 KL-06-114 6/79 KL-06-120 6/79 XL-06-121 6/79 KL-06-123 6/79 XL-07-129 7/79 KL-07-130 7/79 KL-07-134 7/79 KL-07-135 7/79 KL-08-1S3 8/79 KL-08-159 8/79 KL-09-161 9/79 KL-09-163 9/79 KL-10-184 10/79 KL-10-192 KL-11-204 10/79 11/79 KL-11-211 11/79 TCDD Level-ppb Source Document 33 m (ND)* Plff s 1135 and 1148 4 (2.3* 9.1 (7.1)* Plff *s 1285 P lff a 1285 1s.c5, <*0n.o5t* 2o m (ND)* Plff a 1285 //35 Plff a 1135 and 1148 12 (ND)* Plff a 1285 2.8 tl-83* Plff a 1285 2.0 (2.0 + 1.1)* Plff a 1285 .10.5 (4.0)* Plff a 1285 0.5 (0.5)* Plff a 1285 26 Plff a 1131 and 1135 6 Plff* a 1131 and 1135 36 (ND)* Plff* a 1131 and 1135 1.7 (1.2)* Plff* a 1285 ND Plff a 1131 and 1285 2.7 (2.2)* Plff a 1285 ND PI f f a 1131 ND Plff* a 1131 1.1 (1-1>* Plff* a 1285 ND Plff* a 1131 ND Plff* a 1131 and 1285 2.2 (1.7)* P lff a 1285 2.9 (ND)* Plff a 1285 1.2 (ND* Plff* a 1285 0.8 (ND)* Plff a 1285 1.6 (ND)* Plff* a 1285 ND Plff a 1285 2.8 (0.8)* Plff a 1285 ND Deft* a 877 ND Deft* a 877 co* Deft* a 877 ND Deft' a 877 ND Deft* a 877 ND Deft' a 877 C ) * ** Number of total ppb of TCDD co-eluting with 2*3,7,8 TCDD standard. ND None detected at current level of detection or at level of interference. Description KM-02-35 KM-10-174 Date 2/80 10/80 SANTOPHEN 1980 TCDD Level-ppb ND ND Source Document Deft's 877 Plff's 1173 ND None detected at current level of detection or at level of interference. Description S-l Molten 75% S-l Solution SANTOPHEN 1982 Date TCDD Level-ppb 11/12/82 11/12/82 ND ND Source Document Plff's 1377 Plff's 1377 ND = None detected at current level of detection or at level of interference. Description " Santophen 1 SANTOFHEN 1983 Date TCDD Level-ppb 4/19/83 ND Source Description Deft's 957 ND Nope detected at current level of detection or at level of interference.