Document dQvLvwZk2oKYdaKDxZ6wE87RQ

T73L. Worrell ril.SM. Brcrcm ^22./&.jSZz-a - November 2.6, 1968' J. A. ANTONELLI --------------------^ FABRICS & FINISHES DEPARTMENT MARSHALL LABORATORY ---,-- ' COST: -*__FOLYCRECHANE--J ENAMELS AND COMPETITIVE PRODUCTS Attached la the estlawte^l pro^sed~ydu.: It is .based on: (1) two, one-hour exposures per material,(2) six'rata^T>er exposure, (3) the assumption that all materials will"be-run ~sequentiallyi-'(4Xif.adtopsy of-^rats at -l, 7 and 14-daya po8t-e^bsure~with-rOTjbvaI^ndJi>ei8irlPS^o3diual-OgSanig~for: inhalation exposures,' (5> bistoimtfiaoglcTA^^ : system tissues only;- withrother^tissues-being-held^for^si^monthsi^and (6) there will be no unexpected difficuliies." If-we^n-intct-any^timerconsxmiLng.problems ( with any test material. we will get approval::from-ypu:before::p roceeding with it. .......... . He have nor yet decided on sprav concentrationB in the chamber, but this'decision and the-necessary-calculationsjtshould not talce -much-time. - ,--- fSivSijj RSW/jch Attachment RICHARD S. HARITZ ICHIEF, INHALATION TOXICOLOGY SECTION INHALATION COST ESTIMATE - MR-1172 First Material Additional Materials Report Writing & Supervisory Time Pathology $300.00 $150.00 each + 15% $360.00 per material \ DUP040000809 N 25669.01