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AR226-2828 E. I. du Font de Nemours and Company Haskell Laboratoi-y for Toxicology and Industrial Medicine HASKELL LABORATORY REPORT NO. 93-71 MR N0.1 Material Tested; Material Submitted by: Organic Chemicals Department, Jacksci Laboratory Haskell No.: Other Codes; 6869 ACUTE ORAL TEST Procedure: The test niaterial, as an aqueous suspension, was administ ered by intragastric intubation ChR-CD male rats in single doses. Survivors were sacrificed 14 days later. Results: Suspension (%) 40 40 40 40 40 12 12 Dose (me/ke) 17,0004: 11,000* 7,500 5,000 3,400 2,250 670 Mortality! D - 2 d. S - 14 d. S - 14 d. S - 14 d. S - 14 d. S - 14 d. S - 14 d. Clinical Signs Lethal Dose: Prostration on day of dosing; incoordination, weak hypothermia, pallor, prostration, and weight loss on day after dosing Nonlethal Doses: Pallor and hypothermia on day of dosing and weakness on day after dosing at 7500 ing/kg and above; incoordina on day of dosing at 5000 mg/kg and above; weight loss for L-3 da + D - ( ) d. = Found dead ( ) days after dosing; S * Given in divided doses ( ) d. Sacrificed ( ) days after doeing Company s^^-o'-"0'"""'"^0 - 2 - to younige a~o3Silt ChRR--C( D male rats in single dosesB; its Approximate Lethal Dose (ALD) is 17,000 mg/kg of Report by:. ^^f&UJ^LJ Laurel S. Wa Oral Toxicology NB 942, p. 78 LSW:pgh Date: April 6. 1971 Approved by: /^L/} ^ 4 ' -.^Kr Johif^/AA.. <feaappp D4irreeccttor -^>iol Company Sanit.Ksa.... Oe'2- !ot contain TSCA