Document dD902K5Xyxae4x0Rnb1X3Jznq

/ // ,a*$ .. ' ' , SYMPOSIUM ON - .... , 7 . /^M/V.w MM v' /.' ;. /yy ' -W ; V-;,; ? : ,' 1V. '7y7"ENVIRONMENTAL LEAD CONTAMINATION1^ V- 7 ` DECEMBER 13-15/ 1965 . - '. 7 -'y ~ :f * h i' PUBLICATION NO, 1440/: ; ;7.y ff.v . ' 'V;. _ /: /, 1 , ; Reference No. :" 7 7 -y M 1 1 17 ' 7`: ' s **? .' i/'.\*, '- s. .-.; ' - .; ;/-:' ' ; ' (. .... /. 7;/. - ' . ';r . ' W/h/M ' ^ ` ' .: Leo J, Gehrig. 9*1.D., Deoutv Sureeon General p, 2, "sizable base of scientific knowledge of . , > its physiologic and toxic effects" - .' Bov 0. KcCfildih. Ph.D.. PHS /'MM:'-. " ' 7. y . ' M/M-M 2. p. 10, "principal source of atmospheric lead /. is from combustion of leaded gasoline" / ; MIM W : 3. v p. 14, Chart on lead consumption 1926 to 1963. no increase. Keith H. Levis. PHS jij-.. 4- p. 13, "Diet is 907 of intake" Herbert E. Stokinger, PHS /./ 'p. A;., 5. p. 31, "Urinary lead levels" used as basis for determining lead exposure" MW-;/ ;`V 6. Dr. Robert A. Kehoe's address to oanel ?. 51-58 Dr. Robert A. Kehoe M'. ' 7. ivM-V1 Jiff P<` (H ;;r." ?* H'fc m/t-M Wyrv'ii-';-. IM ISVM' O# 9* p. 55, "30 meg. is not level above which one. may conclude that person is suffering, from lead poison ing but below vhich there is definitely no lead poisoning" Dr. Robert A. Kehoe p. 57, gives fatal dose of lead for humans. Lloyd B. Teooer, M.D. Bottom p. 60, "absorption of inorganic lead by direct contact is nil". --"Oral ingestion of materiel which has been applied to skin", --middle of p. 61, "lead oleate seems to be absorbable through the skin of rats, but the evidence for absorption by humans is negligible". / ( J, >i. . ,fi[i ; -t" : . V. ' V. ' i +?(& Yt^yX&\'''\e: \:';-:*.S>'. ^'-y, ' -v Ralph G/"Smith. PhiD., Wayne State University' *' ' A--.*.. ..*!' ' I vr>*^ ; r; 10. v Top of pi 66,- ,,lead.'i'..;?abou't which'acre is,perhaps ., - known ; today; than virtually1',any other toxic substance" ,;ll.\ 'A-W^P' ': i .V'v' ; < J. " A.i yi .13 yity- :;i'7 : -i-'` if J- r^l' ;*i"'. ` '.'-Vt/i Hf5i i.i' Ifi' . .y.te .14 ,15 .16 landjj^'tSTjfblood^vs. urine; i i V''*'' Ralph G. S-aith. Ph.D,, Vayne State,. University '! -V' - ': . . ; vk,- /.V . -- / '.' ' V- -' >*; - '' `H V-- " ;--M ' i r-v.. .. p, 63, "Our knowledge of norraal values of lead in man is virtually, unequalled for aty other substance". , ... "Sefe levels--------adequate". Harriet, L. Hardy, M.D. Bottom of p. 77, ^Crowing tissue is iiore vulnerable v+o iead'Hhsn.:6dult". This paper abounds with- biologi- cal?effects of lead. ', 1 Harriet' L.: Hsrdy .. H.t). : . ;':;i '%y J":'' p. 79, "cigarette snokers. have slightly elevated blood levels" "also beer drinkers". Harriet L. Herd/, M.D. p. 31, quotes Dr. Hill of Royal Society, (Pres.), "Ve need very strong evidence before we made people stop smoking cigarettes and eating fats and sugar.,..." , Melvin V, First. Harvard University p. 89, amount of lead lost to environment. :yp ; . Melviri V. First. Harvard University .' AKA ^'cyAy 17 p. 92, "90-95$ of ingested lead is eliminated promptly .". in feces". .V mtjjV : . Robert J. M. Horton. M.D., PHS '. 1 ,y: \ / K-!:' - .:13 p. 133-139> Sources of lead polution,.Air - Food - Veter ,' "(v'frVt.-i: , Hiif III' fipfely .19 .20 Robert J. M. Horton. M.D., ?KS . - ' * , p. 140, "Cigarettes represent a modest but common source of lead". . ,, Top of p. 146, Dr. Kehoe says lead burden-. ha.a actually gone down in recent years. Qoldvater' at VHO says ssiEsing similarity of the;levels for urine and blood over past two decades. V imm:A p-vxf KE' ^ -f. j U 1 O i Vi) Xf- p. I46, Cholak - remarkable similarity in findings in both their urine and blood lead content (1943-1962) Bottom p. 146, Dr. Lloyd Tgpoer1s - "extremely unlikely of systemic poisoning from entry of inorganic lead com pounds through the intact skin". Top p. 147, He considers lead tetraethyl and tetramethyl os absorbable through skin. Sr. Robert A. Kehoe Top of p. 150, "not the slightest suggestion of a pro gressive increase in the quantity of lead in body", 3 yrs. to -97 yrs. Dr. Robert A. Kehoe1s Summary, p, 155 "ingestion 0.12-0.35 mg./day normally Mid p. 155, urine vs. blood Bottom p. 155 "even vith added lead in diet to 0.53 mg,/day. -- "slight trend toward increase in urine and none in blood". p. 156, Gives amounts of lead that must be ingested to cause poisoning, "soluble lend", note insoluble is excreted in feces. Norton Kelson. N. Y. University Medical Center p. 16(0, "agreement on critical features of lead poisoning and blood and urine levels and thres holds" . Norton Kelson. N. I. University Medical Center Bottom p. 172, "by raeanp of atomic absorption the cost of time of lead in urine has been reduced ----.a minute or tvo at a very low cost". OTHER REFERENCES Cutis - p. 171-176, Vol. 1. No. 4, May 1965, Alexander A. Fisher, M.D. Paraphenylene..... Lead Industries Association, Inc., Facts about lead and Industrial Hygiene, p. 5. Trace Metals Research L&bor&toiy, November 1, 1966 Private communication.