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27-CV-10-28862
CENTRAL ANALYTICAL LABORATORY Report No.___ 33J ___________ Date____ Augusb. A +. -L9.Z8....
Filed in Fourth Judicial District Court 11/17/2017 6:30 PM
Hennepin County, MN
Subject: i r d c 137-092: FC-95/Monkey
Requestor: J-E.-Loag___
Dept. N a m e _JCOXicOlogy_.
R e q u e s t No. __^69507__ ....
Dated__ ______________ ___
Report:
Proj. No.91721100 04
Reference 137--087 by IRDC was a 90 day subacute Rhesus monkey toxicity
study of FC--95. Incorrect (too high) feeding levels were used and all .
animals died within the first few days. The feeding levels were lowered
and the study started again as 137-092. The serum and livers were each
individually submitted for analysis. Each group contained 4 monkeys.
2 male and 2 female as follows:
*
`
Group I
II III
IV
SERUM ANALYSIS
Dosage Level 0
0.5 mg/kg/day 1.5 mg/kg/day 4.5 mg/kg/day
Survival 4/4 4/4 4/4 0/4
Monkey Blank on Method
Dosage Level
-
FC-95 in Serum 2
7355M 7358M 7368F
0 40 0 20 0 15
7463M 7466F
746 2M 7500F
0.5 mg/kg/day
It
1.5 mg/kg/day 11
150 150
250 275
Our newly developed pyrolysis method was used, Precision is estimated to be 10 - 25%.
3M M N 02343995