Document baX236mMnzegLGjqzMdZ46gRo

1022 CHAPTER 45 1956 Guide Table 1. Temperatures and Humidities Applicable to Industrial Air Process Temp. F PAINT application | R.H.% Lacquera: Oil Paints 70-90 180-300 60-90 75 60 60 aTM, booths to have 100 fpm face velocity. Make-up air must be preheated. Ovens must have air removed^to keep fumes below explosive concentration. Equipment must be explosion-proof throughout Room or Process Temp. F R.H.% pharmaceutical Powder storage (prior to mfg.).................................. Manufactured powder storage and packing areas.. Milling room. ........ ....................................................... Tablet compressing....................................................... Tablet coating room................................... .................. Effervescent tablets and powders............................. Hypodermic tablets..................................................... Colloids............................................................................ Cough syrups................................................................ Glandular products........................................... ......... Ampule manufacturing............................................... Gelatin capsules................................................... Capsule storage.............................................................. Micro-analysis........................................................... . Biological manufacturing.......................... ............... Liver extracts................................................................ Serums............................................................................. Animal rooms............................................................... Small animal rooms.................................................... 70 to 80 75 to 80 80 70 to 80 75 to 80 70 80 78 to 80 80 78 75 80 80 70 to 80 74 to 78 75 to 80 75 to 78 30 to 35 15 to 35 35 40 35 15 30 30 to 50 : 40 5 to 10 35 40 to 50 35 to 40 50 35 20 to 30 . 50 40 47 to 48 Gelatin capsules require varying relative humidities, depending upon size of capsule'. Moisture content should not exceed 0.25 gr per cu ft. Various kinds of gelatin require different temperatures. Penicillin incubation process requires holding temperature within 1 deg F, with temperatures and hu midity rigidly controlled during all manufacturing phases. ` Ampule filling requires a 20 percent relative humidity when especially fine powders are used. ' Unooated tablet manufacturing requires accurate oontrol of temperature and relative humidity, since low relative humidity causes formation of a hard outer layer, and high relative humidity retards drying at theLpirvoepreerxrtaratec.ts require a low relative humidity after they are dried. Temperatures higher than 80 F will cause the extracts to deteriorate. Tablet c-nating requires the control of the temperatures of all ingredients and the temperature of air in troduced to coating pans. Sterile conditions are essential in many pharmaceutical processes. Provide suitable air exhaust to re move surplus material from tablet compressing machine. Air filtration m generally required, with positive air filtration in some areas. Animal Rooms in Pharmaceutical Laboratories In the following tabulation each of the items mentioned is equivalent in metabolism to one i Quantity Animal Weight Each 672 110 73 70 21 16 16 5 White Mice Rats Rats Guinea Pigs Rabbits Cats Monkeys Dogs 21 g 200 g 400 g 410 g 2.6 kg 3.0 kg 3.0 kg 14.0 kg Dogs are generally the worst offenders as far as odor generation is concerned. Decontamination of exhaust air is recommended in populated, areas. For good air quality conditions the following space per animal and total air circulation (all outdoor or decontaminated in recirculation) should be provided: Animal Mice Rats Guinea Pigs Rabbits Hamsters Cats T~Wxni cCuU ft 3 4 6 10 8 35 IKft ccffmm 0.5 0.75 1.0 1.9 1.5 10.0 n Industrial Air Conditioning 1023 Table 1. Temperatures and Humidities Applicable to Industrial Air Conditioning--(Continued) Process Temp. F R.H. % Dressing Room.......................... Drying Room............................ Printing Room.......................... Setting Room............................ Developing Room.................... Storage Room............... PHOTO STUDIO ' T 7 :------------------- 45 print!"?- enlarging and drying prwMsses is removed through an independent < haust system, which also serves the lamp houses and dryer hoods. Dust control is essential, and absolute filtration is required in some areas. Process Drying................................... Cutting A Packing Film Base A Paper Storage... Coated Paper A Film Storage. Safety Base Film Storage.......... Nitrate Film Storage........... .. Temp. F PHOTO MATERIAL 70-75 70-75 40-50 R.H. % 40-80 40-60 45-50 tionSr^eWnuSmUat havtal^inhibitor. Positive dust control must be maintained and absolute filtra- In nitrate film area take proper precautions against fires. Recirculated air used for film drying is passed through activated carbon filters. Relative humidity for film storage should never exceed 60 percent with a minimum of 25 percent. Process Manufacturing areas: Thermo setting moulding wimrmnnHs Cellophane wraDDing............ PLASTICS Absolute filtration is required in some areas. Collection and removal of dust and fumes is essential. Temp. F 80 75 to 80 R.H.% 45 to 65 Process PLYWOOD Temp. F R.H. % POULTRY RAISING Incubator. Rrooder: 1st week......... 2nd week Battery room: Starting Growing k^gg storage... .......... .......... 30-60 76-75 50-60 ,, .------------------------------------------------------- made to m^tain a ?^?rtcra ?.una* the summer months, while an attempt is condensation on the eSffl? wImJ0 outdoor temperature during the winter, to minimise eusauoa on tne extenor walls. This applies to houses not having forced ventilation systems. Process Temp. F PRECISION MACHINING Spectrographic analysis matching & special assembly room.. Cement A glue storage.......... A l-wsion parts machining 75-80 75 R.H.% 45-60 45-60